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188261
Recommendations for All-Round Newborns and Infants Hearing Screening in Russian Federation
Published 2021-06-01“…The availability and correct function of hearing research equipment, specialists’ qualifications, study technique and conditions, documents and results transmitting accuracy were estimated. 2) Updating the list of risk factors of hearing loss. …”
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188262
Assessment of right ventricle–to–pulmonary artery coupling by three-dimensional echocardiography in pre-capillary pulmonary hypertension: comparison with tricuspid annular plane sy...
Published 2025-04-01“…Abstract Background The tricuspid annular plane systolic excursion/systolic pulmonary artery pressure ratio (TAPSE/sPAP) has limitations in evaluating right ventricle–to–pulmonary artery (RV-PA) coupling, particularly when pulmonary artery pressure cannot be accurately estimated by tricuspid regurgitation or when TAPSE cannot accurately reflect right ventricular systolic function in certain scenarios. Therefore, this study aimed to explore the value of three-dimensional echocardiography (3DE) coupling parameters in assessing RV-PA coupling in patients with pre-capillary pulmonary hypertension (PH). …”
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188263
Anti-RBD immunoglobulin levels and their predictive value for SARS-CoV-2 neutralization
Published 2025-05-01“…In other words, very similar anti-RBD levels can show very different functional activity. This finding has implications for determining possible future correlates of protection.IMPORTANCEThroughout the SARS-CoV-2 pandemic, neutralizing antibody levels have been central to predict a protective immune response. …”
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188265
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188266
Abnormally high expression of CHI3L1 in peripheral blood mononuclear cells and serum and their potential diagnosis and prediction from lymphoma patients
Published 2025-04-01“…These genes were enriched in functional pathways such as mineral uptake and the Toll-like receptor signaling pathway. …”
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188267
ON POTENTIAL REPRESENTATIONS OF THE DISTRIBUTION LAW OF RARE STRONGEST EARTHQUAKES
Published 2015-09-01“…Assessment of long-term seismic hazard is critically dependent on the behavior of tail of the distribution function of rare strongest earthquakes. Analyses of empirical data cannot however yield the credible solution of this problem because the instrumental catalogs of earthquake are available only for a rather short time intervals, and the uncertainty in estimations of magnitude of paleoearthquakes is high. …”
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188268
Relationship between mucin gene polymorphisms and different types of gallbladder stones
Published 2025-01-01“…The development of gallstones is linked to abnormal cholesterol and bilirubin metabolism, reduced gallbladder function, insulin resistance, biliary infections, and genetic factors. …”
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188269
Fc-competent TIGITx4-1BB bispecific antibody exerts potent long-lasting antitumor activity by potentiating CD8+ T cell activity and Fcγ receptor-mediated modulation of the tumor mi...
Published 2025-02-01“…This study investigated whether ABL112, an Fc-competent bispecific antibody targeting TIGIT and 4-1BB (TIGITx4-1BB), would enhance antitumor activity via Fcγ receptor (FcγR)-mediated macrophage activation and antibody-dependent cell-mediated functions.Methods TIGIT-dependent 4-1BB activation and TIGIT-blocking activity were assessed using reporter Jurkat T cell lines expressing 4-1BB and TIGIT, respectively. …”
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188270
A novel telomere-associated genes signature for the prediction of prognosis and treatment responsiveness of hepatocellular carcinoma
Published 2025-02-01“…The expression and functional significance of ASF1A in HCC cell lines were investigated through colony formation assays, Transwell migration assays, and wound healing experiments. …”
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188271
Reflections and trajectories for interdisciplinary research on the energy transition
Published 2024-06-01“…We have clarified the meaning of the term ‘innovability’©®, formerly in use in the economic and social sciences, which is attributed to a renewed driving force for a new paradigm of development that expresses one of the most crucial challenges of our time and the need for a ‘solidary’ convergence between the two inescapable instances of ‘innovation’ and ‘sustainability’, as if they were opposites and contrasts: beyond the term used, in a historical moment characterised by environmental, social and economic emergencies, Humanity promotes one of its prerogatives, the use of the ‘things’ that nature makes available to us to do something other than their primary function (innovation), aware that those resources are not inexhaustible (sustainability). …”
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188273
Quercetin modulates transcription of the apoptotic and CatSper genes and optimises post thaw viability and kinematics of buck spermatozoa
Published 2025-07-01“…Abstract Oxidative stress during semen processing affects sperm membrane integrity, leading to compromised sperm membrane functions and kinematics, often resulting in reproductive losses. …”
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188274
The Bottleneck in the Scalar Dissipation Rate Spectra: Dependence on the Schmidt Number
Published 2024-12-01“…To comprehend the flow structures responsible for the bottleneck, visualizations of <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>θ</mi><msup><mo>∇</mo><mn>2</mn></msup><mi>θ</mi></mrow></semantics></math></inline-formula> and probability density functions at various <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>S</mi><mi>c</mi></mrow></semantics></math></inline-formula> values are presented and compared with those of <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>u</mi><mi>i</mi></msub><msup><mo>∇</mo><mn>2</mn></msup><msub><mi>u</mi><mi>i</mi></msub></mrow></semantics></math></inline-formula>. …”
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188275
Immunoexpression of tumor suppressor genes p53, p21WAF1/CIP1 and p27KIP1 in humam astrocystic tumors Imuno-expressão dos genes supressores tumorais p53, p21WAF1/CIP1 e p27KIP1 em t...
Published 2007-12-01“…These results indicated the p53 mutation as an initial, relevant and potentially predictor of tumor progression event in astrocytomas, with the detection of p21 protein as an important resource for the deduction of functional situation of this gene. Moreover, the activation of p27KIP1 was preserved in the astrocytic tumors and its cytoplasmic manifestation seems to be resultant of its nuclear expression, not demonstrating a direct impact in astrocytomas tumorigenesis.…”
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188276
Single-cell and machine learning approaches uncover intrinsic immune-evasion genes in the prognosis of hepatocellular carcinoma
Published 2024-12-01“…Various tools, including the Human Protein Atlas, cBioPortal, single-cell analysis, machine learning, and Kaplan-Meier plot, were used to analyze IIEGs. Functional enrichment analysis was conducted to explore potential mechanisms. …”
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188277
Landscape Planning and Design of Urban Rivers with Environmental Approach (Case Study: Farahzad River Valley in Tehran)
Published 2022-12-01“…At the present time, structure and function of these valuable elements have been ruined due to non-planning growth and regardless to environmental subjects in municipal management and landscape planning that they have been converted to the runoff canal network or effluent. …”
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188278
Genome-Wide Identification, Exogenous Hormone Response, Gene Structure, and Conserved Motif Analysis of the <i>GRF</i> Gene Family in <i>Cerasus humilis</i>
Published 2025-06-01“…The results laid the foundation for further research on the biological functions of the <i>GRF</i> genes in <i>C. humilis</i>.…”
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188279
Three-compartment, two-parameter concentration-driven model for uptake of excess atmospheric CO<sub>2</sub> by the global ocean
Published 2025-06-01“…Although the concentration-driven model developed here cannot be used prognostically (to assess model skill in replicating atmospheric CO<span class="inline-formula"><sub>2</sub></span> over the industrial period or to examine response to changes in emissions), the model is useful diagnostically to examine the disposition of excess carbon into pertinent global compartments as a function of time over the Anthropocene. More importantly, the model and the parameters developed here can be used with confidence to represent ocean uptake of excess CO<span class="inline-formula"><sub>2</sub></span> in emissions-driven models.…”
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188280
ASSESSMENT OF THE PARAMETERS OF THE INTEROCCLUSION RELATIONSHIP IN THE PROCESS OF MESIALIZATION OF THE LOWER MOLARS WITH THE USE OF T-SCAN
Published 2020-06-01“…The use of the T-scan apparatus is an accurate and informative tool for analyzing the distribution of functional occlusal force load within the dentition. …”
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