Spatio-Temporal Evolution of Net Ecosystem Productivity and Its Influencing Factors in Northwest China, 1982–2022 by Weijie Zhang, Zhichao Xu, Haobo Yuan, Yingying Wang, Kai Feng, Yanbin Li, Fei Wang, Zezhong Zhang

“…The carbon cycle in terrestrial ecosystems is a crucial component of the global carbon cycle, and drought is increasingly recognized as a significant stressor impacting their carbon sink function. Net ecosystem productivity (NEP), which is a key indicator of carbon sink capacity, is closely related to vegetation Net Primary Productivity (NPP), derived using the Carnegie-Ames-Stanford Approach (CASA) model. …”
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Discovery of natural CdnP inhibitors through structure-based virtual screening and molecular dynamics simulations by Xiaoxia Gu, Chaohu Xiong, Xinyu Wang, Hucheng Zhu, Weiguang Sun, Yan He, Jinwen Zhang

“…ABSTRACT Tuberculosis, caused by Mycobacterium tuberculosis, remains one of the most lethal infectious diseases both historically and in the post-coronavirus disease 2019 era. CdnP (Rv2837c) functions as a bifunctional oligoribonuclease and 3′(2′)-phosphoadenosine 5′-phosphate-phosphatase that impedes host immune responses by recognizing bacterial cyclic dinucleotides such as c-di-AMP, which serve as pathogen-associated molecular patterns. …”
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Optimal Coordinated Flood Control Scheduling of Three Gorges and Qingjiang Cascade Reservoirs by ZHAO Hui, ZHU Yu-xin, LIU Yuan, HUANG Bin, PANG Shu-sen, HUANG Di

“…The coordinated scheduling scheme ensured that Qingjiang reservoir reached its highest water level before mid-July and maintained high-water-level operation until the flood season ended in the Yangtze River Basin, thereby fully achieving its flood peak shaving and detention functions. [Conclusion] This study proposes innovative strategies for activating flood control capacity in the Three Gorges and Qingjiang cascade reservoirs, specifically tailored to different regional flood compositions, thereby providing decision-makers with diversified scheduling schemes. …”
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Emerging Diagnostic Approaches for Musculoskeletal Disorders: Advances in Imaging, Biomarkers, and Clinical Assessment by Rahul Kumar, Kiran Marla, Kyle Sporn, Phani Paladugu, Akshay Khanna, Chirag Gowda, Alex Ngo, Ethan Waisberg, Ram Jagadeesan, Alireza Tavakkoli

“…Point-of-care ultrasound and portable diagnostic devices have expanded real-time imaging and functional assessment capabilities across diverse clinical settings. …”
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Effect of Alternate day fasting over Metabolic dysfunction-associated steatohepatitis in adult offspring of dams exposed to cafeteria diet during pregnancy and lactation. by Martín G. García-Juárez, Tania G. Heredia-Torres, Daniel Arellanos-Soto, Blanca E. Álvarez-Salas, Alberto Camacho-Morales, Ana María G. Rivas-Estilla

“…At the end of the fasting protocol, plasma samples were taken and beta-hydroxybutyrate (BHB) concentration was measured; in addition, samples of the left lateral lobe of the liver were taken at slaughter to evaluate by qPCR the effect of intermittent fasting on the expression of metabolic function markers involved during MASH: fibrosis (TGFβ, Col1a1), steatosis (PLIN2, ApoB100, Mylcd, PPARPα) and inflammation (Mcp-1). …”
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Mapping the Λ_sCDM Scenario to <i>f</i>(<i>T</i>) Modified Gravity: Effects on Structure Growth Rate by Mateus S. Souza, Ana M. Barcelos, Rafael C. Nunes, Özgür Akarsu, Suresh Kumar

“…However, when considered within general relativity, this scenario does not predict any effects on the evolution of the matter density contrast beyond modifications to the background functions. In this work, we propose a new gravitational model in which the background dynamics predicted by the <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi mathvariant="sans-serif">Λ</mi><mi mathvariant="normal">s</mi></msub></semantics></math></inline-formula>CDM framework are mapped into <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>f</mi><mo>(</mo><mi>T</mi><mo>)</mo></mrow></semantics></math></inline-formula> gravity, dubbed <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>f</mi><mrow><mo>(</mo><mi>T</mi><mo>)</mo></mrow><mtext>-</mtext><msub><mi mathvariant="sans-serif">Λ</mi><mi mathvariant="normal">s</mi></msub></mrow></semantics></math></inline-formula>CDM, rendering the models indistinguishable at the background level. …”
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The Impact of Radiation Dose on CT‐Based Body Composition Analysis: A Large‐Animal Study by Luca Salhöfer, Gregor Jost, Mathias Meetschen, Daniel vanLandeghem, Michael Forsting, Denise Bos, Christian Bojahr, Rene Hosch, Felix Nensa, Hubertus Pietsch, Johannes Haubold

“…Typically, the segmentation of muscle and fat compartments is performed with a thresholding‐based subsegmentation, which might be influenced by the image noise as a function of radiation dose. This study was performed to investigate the impact of the radiation dose on a fully automated, volumetric CT‐based BCA. …”
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Incidence of Delirium Tremens in Acute Poisoning by Psychopharmacological Drugs or Corrosive Substances and Its Prevention Using Intestinal Lavage: on the Pathogenesis of Delirium... by V. A. Matkevich, M. M. Potskhveriya, A. G. Vorobyeva, V. S. Shukshin

“…The observed phenomenon of decreased risk of delirium tremens development in patients who underwent intestinal lavage suggests that the pathogenesis of delirium tremens is associated with morphological and functional disorders of the gastrointestinal tract, the key link of which is the excess proliferation of microflora, for the vital activity of which ethanol is necessary. …”
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Establishment of patient-derived 3D in vitro models of sarcomas: literature review and guidelines on behalf of the FORTRESS working group by Lore De Cock, Ieva Palubeckaitė, Francesca Bersani, Tobias Faehling, Sandro Pasquali, Sam Umbaugh, Michael Torsten Meister, Molly R. Danks, Piotr Manasterski, Richard Miallot, Manuela Krumbholz, Siyer Roohani, Dominique Heymann, Florencia Cidre-Aranaz, Agnieszka Wozniak, Patrick Schöffski, Judith V.M.G. Bovée, Alessandra Merlini, Sanne Venneker

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Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject ‘cold’ tumors by Laetitia Fend, Eric Quemeneur, Monika Semmrich, Jean-Baptiste Marchand, Matilda Rehn, Nathalie Silvestre, Linda Mårtensson, Johann Foloppe, Ingrid Teige, Björn Frendeus, Petra Holmkvist, Carolin Svensson, Christelle Remy, Patricia Kleinpeter, Jules Deforges, Fred Junghus, Kirstie L Cleary, Mimoza Bodén

“…Here we assess and identify spatially restricted exposure to a novel strongly Treg-depleting, checkpoint-blocking, vectorized αCTLA-4, as a highly efficacious and potentially safe strategy to target CTLA-4.Methods A novel human IgG1 CTLA-4 antibody (4-E03) was identified using function-first screening for monoclonal antibodies (mAbs) and targets associated with superior Treg-depleting activity. …”
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Alte und neue Wege in der Rheometrie der Polymer-Schmelzen by Joachim Meissner

“…Capillary rheometry is the standard method for the determination of the viscosity function up to high shear rates. In capillary flow, the melt elasticity leads to extrudate swell, and the melt fracture phenomenon terminates the range of stable, laminar flow. …”
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Cryo-EM reveals a double oligomeric ring scaffold of the CHIKV nsP3 peptide in complex with the NTF2L domain of host G3BP1 by Yuanzhi Liu, Jie Wang, Yinze Han, Xiaoyan Xia, Rui Zeng, Xinyu Fan, Bo Zhang, Kaituo Wang, Jian Lei

“…Overall, our findings present the structural and functional mechanisms on CHIKV nsP3 modulating host G3BP1 and provide a potential antiviral target based on the protein–protein interaction interface.IMPORTANCEChikungunya virus (CHIKV) is an arbovirus responsible for causing fever, headache, and severe joint pain in humans, with widespread outbreaks affecting millions worldwide. …”
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Exposure of broiler chickens to deoxynivalenol and Campylobacter jejuni induces substantial changes in intestinal gene expression by Wageha A. Awad, Daniel Ruhnau, Barbara Doupovec, Claudia Hess, Dian Schatzmayr, Michael Hess, Bertrand Grenier

“…The actual study also demonstrated that co-exposure of broiler chickens to DON and C. jejuni resulted in a decreased barrier function via downregulation of OCLD mRNA expression. …”
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Percepciones de futuros maestros sobre motricidad en educación infantil: un estudio exploratorio en estudiantes de último curso (Perceptions of future teachers on motricity in ear... by Josué Prieto Prieto, David Cerro Herrero

“…Conscious of the role of motor function in the integral development of individuals, motricity is presented as a topic of undoubted relevance within schools. …”
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Correlation between interleukins in aqueous humor and vitreous humor of vitreoretinal lymphoma patients by Yurun Liu, Xinyi Zhou, Kaiyu Zhang, Shixue Liu, Ruiwen Li, Yifan Gong, Zhujian Wang, Tingting Jiang, Ting Zhang, Gezhi Xu, Junxiang Gu, Qing Chang

“…For both IL-10 and IL-6, the AqH concentrations were positively correlated with VH concentrations in the form of power functions (P < 0.001 and P < 0.001, respectively). …”
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Preparation of future teachers for innovative activities in pedagogical and technological educational environment by N. I. Naumkin, N. N. Shekshaeva, V. F. Kupryashkin, E. V. Zabrodina

“…The environment includes conceptually-targeted, infrastructural, content-based, psychological-didactic, methodological-technological and relaxation-diagnostic components, its features are the following: 1) focus on innovative training of technology teachers as directly related to the material objects of the innovative economy of the country; 2) universality in the form of the possibility of using it to solve other educational tasks; 3) graphical visualisation of the environment model with an indication of the hierarchy and interrelation of components, its scale, combinatoricity and functional sufficiency; 4) compliance of the environment with all the requirements of regulatory documents on educational activities at the university; 5) possibility of full-scale implementation of modern approaches to learning (innovative, personalised, environmental, project, etc.); 6) possibility of constant monitoring and control of the implementation of the environment within its relaxation and diagnostic component; 7) use of modern educational technologies, including digital; 8) possibility of obtaining specialised knowledge and studying other disciplines within the framework of using network learning; 9) innovativeness of the environment, determined by the novelty of the approach to teaching the teachers innovation technology and its effectiveness.To teach innovation activity in this environment, a model of a methodological system for the formation of competence in innovation activity among future technology teachers has been created, combining conceptually-targeted, meaningful, instrumental-activity and reflexive-evaluative components. …”
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Noise exposure, hearing loss and cognitive impairment: a cross-sectional study based on an occupational health surveillance cohort in China by Lei Huang, Linjuan Li, Juan Wang, Shushan Zhang, Huiyi Wu, Yajia Lan, Junying Li, Yang Zhang, Yang Zhang

“…The Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) were used to assess cognitive function. Structural equation modeling (SEM) was used to analyze the potential pathways and specific effect sizes of CNE, hearing loss and cognitive impairment.ResultsThe mean age of the research subjects was 34.3 (SD, 9.89). …”
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The Impact of Hotspot-Targeted Interventions on Malaria Transmission in Rachuonyo South District in the Western Kenyan Highlands: A Cluster-Randomized Controlled Trial. by Teun Bousema, Gillian Stresman, Amrish Y Baidjoe, John Bradley, Philip Knight, William Stone, Victor Osoti, Euniah Makori, Chrispin Owaga, Wycliffe Odongo, Pauline China, Shehu Shagari, Ogobara K Doumbo, Robert W Sauerwein, Simon Kariuki, Chris Drakeley, Jennifer Stevenson, Jonathan Cox

“…Secondary outcome measures were parasite prevalence inside hotpots, parasite prevalence in the evaluation zone as a function of distance from the hotspot boundary, Anopheles mosquito density, mosquito breeding site productivity, malaria incidence by passive case detection, and the safety and acceptability of the interventions. …”
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MAGICAL REALISM IN THE CONTEXT OF POSTMODERN AESTHETICS: HERMANN KASACK’S “THE CITY BEYOND THE RIVER” AND MAX KIDRUK’S “DON’T LOOK BACK AND STAY QUIET” INTER- TEXTUAL CONNECTIONS... by Tetiana V. Bykova, Nina D. Osmak

“…The principle of intertextuality is key to the artistic construction of both works and is manifested across several levels in both novels: 1) existential themes and issues, particularly in exploration of death, understanding the problems of experiencing one’s way of being and the problems of cognition / self-knowledge; 2) at the level of the plot, where the key to both novels is the transformation of the myth about Orpheus and Eurydice with a reinterpreting of the motif of breaking the taboo; 3) at the motif level, through the meaning-making and plot-shaping functions of the motifs of numbers, journeys, and mirrors; 4) at the chronotopic level, through the symbolic representation of time and space in magical realism; 5) at character level, through the creation of a new type of hero who possesses sacred knowledge; 6) finally, at the level of ideological transformation and the external return to oneself, through the exploration of the problem of life and death, and the idea of inability of scientific knowledge for the complete understanding of both the human being and the world. …”
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From colorless to pink: Structural insights into vitamin B12-induced color change in monoclonal antibodies by Kai-feng He, Hao-dong Cui, Wen-hui Deng, Na Xing, Guo-jian Liu, Abdallah Iddy Chaurembo, Li-dan Fu, Yuan Li, Xin-yue Tong, Han-bin Lin, Chun-he Wang

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