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  1. 84761

    Evolution of Innovative Surgical Techniques Using the Example of Selective Splenorenal Anastomosis Surgery by A. Yu. Anisimov, F. B. Mavlonov, D. E. Erkinova, A. I. Andreev, R. A. Ibragimov, E. Yu. Mandryka

    Published 2025-01-01
    “…RELEVANCE Despite the obvious successes of transjugular intrahepatic portosystemic shunt and orthotopic liver transplantation in some high-tech centers of the Russian Federation, the relevance of substantiating the use of selective splenorenal anastomoses in the treatment plan for portal hypertension, when hundreds of patients return to emergency surgery departments every year after conservative treatment with new episodes of bleeding, liver failure and high mortality rates, is beyond doubt.AIM OF THE STUDY To substantiate the viability of the selective splenorenal anastomosis operation by improving the technique of performing the intraoperative vascular maneuver exposure and venous reconstruction through the use of original modern innovative approaches.MATERIAL AND METHODS A retrospective controlled clinical study included 56 patients with intrahepatic portal hypertension with relatively preserved liver function, in whose complex treatment program for secondary prevention of bleeding, various options for selective splenorenal bypass surgery were used. …”
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  2. 84762
  3. 84763
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  6. 84766
  7. 84767
  8. 84768

    Contributory factors to partial implementation of prevention of mother to child transmission policy in South Africa by Hermina Manjekana Dyeshana, Sibusiso Memory Zuma

    Published 2025-07-01
    “…Conclusion The study ascertained PMTCT policy implementation gaps that still exist as a result of non- compliance to interventions advocated for by the PMTCT policy Poor adherence and non -adherence to PMTCT policy may have an impact on the ultimate objectives of the whole program and derail the country to achieve eMTCT by 2030.…”
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  9. 84769
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  11. 84771
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  15. 84775

    INVESTIGATION OF THE OPTICAL BONE DENSITY OF THE ALVEOLAR PROCESSES IN THE AREA OF DEFECTS OF DENTITION by S.A. German

    Published 2018-03-01
    “…HU) , and studied its changes depending on the time of tooth extraction using free program "OneVolumeViewer". As a result of our research determined the optical density of bone tissue of alveolar processes of jaws in the region of defects of the dentition, which varies from 420,445±5,264 до 2829,754±3,535 HU. …”
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  16. 84776
  17. 84777

    TERAPIA COM CÉLULAS CAR-T NO TRATAMENTO DE LEUCEMIA LINFOBLÁSTICA AGUDA by MARIA CLARA DE LIMA PIRES, Yasmin Ribeiro MACHADO, Maria Eduarda Monteiro DA SILVA

    Published 2025-05-01
    “…Para isso, foi realizada uma abordagem metodológica de caráter descritivo, por meio da revisão integrativa da literatura sobre publicações nacionais e internacionais indexadas em bancos de dados virtual, como o PubMed, Scielo, Instituto Nacional do Câncer (INCA), Instituto Butantã, American Cancer Society, Surveillance Research Program (SEER), Food and Drug Administration (FDA) e Novartis, dentro do período delimitado para esta pesquisa, nos anos de 1990 a 2024. …”
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  18. 84778

    Serum Osteopontin Enhances Hepatocellular Carcinoma Diagnosis and Predicts Anti-PD-L1 Immunotherapy Benefit by Wu M, Zou F, He S, Pi Y, Song Y, Chen S, Li L

    Published 2025-04-01
    “…Miantao Wu,1,2,* Fei Zou,3,* Suyin He,4,* Yingqi Pi,5 Yiling Song,1,2 Shulin Chen,1,2 Linfang Li1,2 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China; 2Department of Laboratory Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China; 3Department of Oncology, The First Affiliated Hospital of Chongqing Medical and Pharmaceutical College, Chongqing Key Laboratory of Prevention and Treatment for Occupational Diseases and Poisoning, Chongqing, People’s Republic of China; 4State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, People’s Republic of China; 5Department of Clinical Laboratory, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, People’s Republic of China*These authors contributed equally to this workCorrespondence: Linfang Li, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, People’s Republic of China, Email lilf@sysucc.org.cn Shulin Chen, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, People’s Republic of China, Email chenshl@sysucc.org.cnBackground: Osteopontin (OPN), a phosphorylated glycoprotein encoded by SPP1, critical in hepatic inflammation and fibrosis, requires further investigation for its role on hepatocellular carcinoma (HCC) and predictive value for anti-programmed cell death ligand 1 (anti-PD-L1) immunotherapy responses.Methods: Publicly available datasets were utilized to explore OPN expression in HCC. …”
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