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83701
Exploring the magnitude and predictors of the long-term psychological impact of COVID-19 on frontline healthcare workers in Vietnam: a multi-center, cross-sectional study
Published 2025-04-01“…As HCWs may overlook their mental health issues, a screening program with psychological support services should accompany them early in future pandemics. …”
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Protective Effect of Aerobic Training and Royal Jelly on Cellular senescence Markers of Cardiomyocytes in Obese Rats
Published 2022-06-01“…The supplement groups received 100 mg of royal jelly (per kg of body weight) diluted in distilled water orally during the intervention period. Aerobic exercise program including running on the treadmill with an intensity of 50-60% maximal oxygen consumption (VO2max), was performed five days a week for eight weeks. 48 hours after the last training session, rats were anesthetized with a combination ketamine and xylazine, and after extraction, the heart tissue was placed in a nitrogen tank and sent to the laboratory to measure p16 and p21 gene expression levels. …”
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83703
Impact of 16/8 time-restricted eating on body composition and lipolytic hormone regulation in female DanceSport dancers
Published 2025-12-01“…Objective The aim of this study was to investigate the effect of a 16/8 time-restricted eating (TRE) program over 6 weeks on body composition and lipolytic hormone levels in female DanceSport dancers. …”
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Standardising the administration of joint injections across the Wolverhampton NHS Trust: a service improvement project in rheumatology through the lens of medical education
Published 2025-06-01“…Four trained rheumatology doctors, supervised by a consultant, led a teaching program. Virtual meetings guided plan–do–study–act (PDSA) cycles and driver diagrams to ensure constructive alignment.The goal was to advance learners from the Dreyfus level of ‘Novice 1’ to 'Competent 1’. …”
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Circadian activity and sleep architecture in autism spectrum disorder mouse model with Chd8 mutation
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Endovascular treatment combined with eptifibatide in patients with acute ischemic stroke: a prospective, multicenter study
Published 2024-11-01“…Logistic regression analysis showed that an admission National Institutes of Health Stroke Scale (NIHSS) score of > 15 was a risk factor for poor prognosis in patients with acute ischemic stroke after EVT combined with eptifibatide (OR = 0.118, 95%CI: 0.046-0.307; P = 0.000), while an Alberta Stroke Program Early CT Score (ASPECTS) of ≥ 6 was a protective factor for good prognosis (OR = 5.871, 95%CI: 1.812-19.020; P = 0.003). …”
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A Descriptive Cross-Sectional Study of Manipulative Dexterity on Different Subtypes of Multiple Sclerosis
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A study of acute toxicity of newly synthesized compound on adult hydrobiont Danio rerio
Published 2021-03-01“…Statistical analysis of the results was performed using the program Statistica 6. Results. According to the obtained data, graphs of the dependence of the concentration on the fish mortality percentage were constructed. …”
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Copa do Mundo da FIFA e Jogos Olímpicos e Paralímpicos no Brasil: legados no município de Campinas-SP (FIFA World Cup and the Olympic and Paralympic Games in Brazil: Legacies in t...
Published 2021-04-01“…Semi-structured interviews with city stakeholders and in loco observations were used for data collection, then transcription content analysis was performed by Iramuteq software. The program identified four different categories: High Performance Sport Center (HPSC), Negative Legacies, Delegation Reception and Safety. …”
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Dupilumab and atopic march; Reduction of incident allergic events or Clinical control?
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PEG-Polymeric Nanocarriers Alleviate the Immunosuppressive Effects of Free 4-Thiazolidinone-Based Chemotherapeutics on T Lymphocyte Function and Cytokine Production
Published 2024-12-01“…Jana Tulinska,1,* Lesya Kobylinska,2,* Miroslava Lehotska Mikusova,1 Julia Babincova,3 Natalia Mitina,4 Eva Rollerova,1 Aurelia Liskova,1 Nikola Madrova,1 Radka Alacova,3 Alexander Zaichenko,4 Roman Lesyk,5 Mira Horvathova,1 Michaela Szabova,1 Norbert Lukan,1 Sandor Vari6 1Faculty of Medicine, Slovak Medical University, Bratislava, Slovakia; 2Department of Biochemistry, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine; 3Faculty of Public Health, Slovak Medical University, Bratislava, Slovakia; 4Department of Organic Chemistry, Lviv Polytechnic National University, Lviv, Ukraine; 5Department of Pharmaceutical, Organic and BioOrganic Chemistry Danylo Halytsky Lviv National Medical University, Lviv, Ukraine; 6International Research and Innovation in Medicine Program, Cedars - Sinai Medical Center, Los Angeles, CA, USA*These authors contributed equally to this workCorrespondence: Lesya Kobylinska, Department of Biochemistry, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine, Email KobylinskaLesya@meduniv.lviv.ua Norbert Lukan, Faculty of Medicine, Slovak Medical University, Bratislava, Slovakia, Email norbert.lukan@szu.skPurpose: Our study aimed to assess the effects of anticancer 4-thiazolidinone-based free water-insoluble therapeutics Les-3288 and Les-3833 and their waterborne complexes with branched PEG-containing polymeric carriers (A24-PEG550 and A24-PEG750) on immune response.Methods: Human peripheral blood was used to study in vitro lymphocyte proliferative function, leukocyte phagocytic activity and respiratory burst, and cytokine production.Results: The binding of the polymer to the anticancer drug Les-3288, which is intended to mitigate the immunosuppressive effects of the free drug on the proliferative activity of T lymphocytes and T-dependent B cells, demonstrated comparable efficacy for both A24-PEG750 and A24-PEG550 nanocarriers. …”
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Etlingera Elatior Inflorescence Extract Mitigates Acute Gastric Ulcers by Suppressing the Expression of Inducible Nitric Oxide Synthase in Ethanol-Induced Wistar Rats
Published 2025-06-01“…Deshanda Kurniawan Prayoga,1,* Diah Lia Aulifa,2,* Arif Budiman,3,* Jutti Levita,4,* Supat Jiranusornkul5,* 1Doctoral Program in Pharmacy, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java, Indonesia; 2Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Padjadjaran University, Sumedang, Indonesia; 3Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Padjadjaran University, Sumedang, Indonesia; 4Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Padjadjaran University, Sumedang, Indonesia; 5Department of Pharmaceutical Science, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand*These authors contributed equally to this workCorrespondence: Jutti Levita, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java, 46363, Indonesia, Email jutti.levita@unpad.ac.idBackground: Ethanol consumption by oral route can induce gastric cell necrosis and vascular damage due to excessive reactive oxygen species (ROS) production. …”
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