Effects of autophagy in the process of diabetic nephropathy by LIU Nan, ZHONG Liang-bao, ZHANG Rui-cheng, LIANG Hai-qin, DING Li-li

“…Objective To investigate the expression of autophagy in glomerular cells of rats with diabetic nephropathy,observe the effects of insulin on the autophagy of podocytes in rats with diabetic nephropathy,and clarify the role of autophagy in the pathogenesis of diabetic nephropathy.Methods Fifty healthy male Wistar rats were adaptively fed for 1 week and randomly divided into two groups.There were 10 rats in the control group A.In the remaining 40 rats,diabetes mellitus models were established by intraperitoneal injection of streptozotocin.After induction of DM,the 40 rats were divided into group B(n = 20) given citrate buffer solution,and group C(n = 20) given subcutaneous injection of insulin by 1.5 U/kg 24 h for 4 weeks.After 4 weeks,we collected the urine and blood samples for determination of urea nitrogen,creatinine,and blood glucose.We observed the pathological changes by PAS stain of the kidney tissues,the changes of podocyte processes by transmission electron microscope(TEM),and the LC3I/II expression was analyzed by Western blotting.Results As compared with group A,the urinary albumin and blood glucose in groups B and C were increased significantly(P<0.01),the glomerular basement membrane(GBM) thickened,mesangial region widened,the matrix increased,the podocyte processes widened and fused,and LC3- Ⅱ /LC3-Ⅰ reduced significantly(P<0.01).As compared with group B,pathological changes in group C were alleviated,and the LC3-Ⅱ /LC3-Ⅰexpression was up-regulated(P<0.01).Conclusions Autophagy is hampered within the kidney of diabetic rats.Insulin can alleviate the pathological changes of glomerulus cells and the damage to podocytes,which might be contributed to the autophagy of podocytes.To maintain a balanced podocyte autophagy could be an effective measure in slowing the progression of diabetic nephropathy.…”
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GRAPHICAL MODELS OF THE AIRCRAFT MAINTENANCE PROCESS by S. V. Daletskiy, S. S. Daletskiy

“…The aircraft maintenance is realized by a rapid sequence of maintenance organizational and technical states, its research and analysis are carried out by statistical methods. The maintenance process concludes aircraft technical states connected with the objective patterns of technical qualities changes of the aircraft as a maintenance object and organizational states which determine the subjective organization and planning process of aircraft using. …”
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PRODUCTION PROCESS IN ECONOMIC RELATION SYSTEM by A. I. Vankevich

“…Production is considered as a process, where people, being interconnected by some certain production relations, create material benefits in the form of means of production and personal items that are necessary for people existence. …”
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The health organizations and the management learning process by Adriano Antonio Marques de Almeida

“…It is imperative that, in addition to an environment turned to learning, there are the involvement and the commitment of the leaders in these organizations, so that the employees are stimulated and invited to participate in this development process. This paper proposed identifying the organizational learning processes adopted in private hospitals from the theoretical background about organizational learning and culture. …”
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On the question of applying discounts in the marketing process by A. Yu. Yanchenko, M. M. Repilova

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Process of cartographic generalization in maps digitalization by Minashkina Natalia, Valieva Albina, Ibraimova Aziza, Rakhimbabayeva Marhamat, Islamova Zulfiya

“…The initial map compiler refers to the original map developed through this compilation process, on which the content elements are applied in accordance with the requirements of the editorial documents.…”
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Solder Paste Process of Hybrid Circuits by Kazuo Tazuke, Youichiro Ohnishi, Kohei Adachi, Hayato Takasago

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Analytical Modeling of Particle Scratching Process by Shouhong Chen, Mingjun Sun, Yuantao Fan, Fangchen Yin, Jixiang Huang, Shengui Huang

“…This study develops a new physical and analytical model for the particle scratching process, where a particle is modeled as a sphere. …”
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Process empowerment for robust intrinsic motivation by Stas Tiomkin, Christoph Salge, Daniel Polani

Subjects: “…information processing in dynamical control systems…”
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Antioxidant Activity of Culinary-Processed Food by Monika Sejbuk, Anna Zinkow, Małgorzata Kuczyńska, Monika Cyuńczyk, Iwona Mirończuk-Chodakowska, Anna M. Witkowska

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Understanding Typical Emotions In The Design Process by Amic G. Ho

Subjects: “…Design Process…”
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Surface Energy in the Processes of Disintegration of Solids by V. T. Fedorov, M. N. Kokoev

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Newt Opportunities for Understanding the Dedifferentiation Process by Ziad Y. Chaar, Catherine Tsilfidis

“…Urodele amphibians, such as the newt Notophthalmus viridescens, have the unique ability to regenerate limbs, spinal cord, eye structures, and many vital organs through a process called epimorphic regeneration. Although the cellular basis of regeneration has been studied in detail, we know relatively little about the molecular controls of the process. …”
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IMPACT OF GLOBALIZATION PROCESSES ON RUSSIAN ECONOMY by Inessa Penkova, Ovsanna Dzhavadova

“…The article aims at revealing the degree and power of the worldwide globalization processes influence on Russian national economy. In the process of research, the tasks were settled to define and analyze the key indicators characterizing the principal effects of globalization. …”
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The Influence of the Cancer Microenvironment on the Process of Metastasis by Andra R. Frost, Douglas R. Hurst, Lalita A. Shevde, Rajeev S. Samant

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On the Stationary Measure for Markov Branching Processes by Anthony G. Pakes

Subjects: “…Markov branching process…”
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СOMPANY BALANCING PROCESS MODELING by B. Odintsov, A. Romanov

“…Resource balancing at a company is seen as a static stage in the balance acquisition process between the development stage and the stabilization stage. …”
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SHIFT OPERATOR FOR PERIODICALLY CORRELATED PROCESSES

“…The existence of shift for periodically correlated processes and its boundedness are investigated. Spectral criteria for these non-stationary processes to have such shifts are obtained.…”
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CALCULATION AND OPTIMIZATION OF DIE FORGING PROCESSES by Yu.N. REZNIKOV, A.V. VOVCHENKO

“…The review of methods of calculation and optimization of die forging processes is submitted. The scheme of direct and inverse mathematical simulation of metal forming and methods realization of calculation are considered. …”
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Federalism and constituting of an order: Decision or process? by Kovačević Bojan

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