Social Media Suicide Watch by Katherine Prothro

“…AI can be used to retrospectively analyze posts from individuals who died by suicide to identify patterns imperceptible to the human eye. These algorithms could then be applied to current users to more accurately identify at-risks populations. …”
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18F-MK-6240 tau PET in patients at-risk for chronic traumatic encephalopathy by Michael L. Alosco, Jhony Mejía Pérez, Julia E. Culhane, Ranjani Shankar, Christopher J. Nowinski, Samantha Bureau, Nidhi Mundada, Karen Smith, Alinda Amuiri, Breton Asken, Jenna R. Groh, Annalise Miner, Erika Pettway, Sydney Mosaheb, Yorghos Tripodis, Charles Windon, Gustavo Mercier, Robert A. Stern, Lea T. Grinberg, David N. Soleimani-Meigooni, Bradley T. Christian, Tobey J. Betthauser, Thor D. Stein, Ann C. McKee, Chester A. Mathis, Eric E. Abrahamson, Milos D. Ikonomovic, Sterling C. Johnson, Jesse Mez, Renaud La Joie, Daniel Schonhaut, Gil D. Rabinovici

“…Two had Thal Phase 1 for Aβ; one showed a laminar pattern of 3H-MK-6240 autoradiography binding in the superior temporal cortex and less so in the dorsolateral frontal cortex, corresponding to tau-immunoreactive lesions detected using the AT8 antibody (pSer202/pThr205 tau) in adjacent tissue sections. …”
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Dynamic changes of aroma substances during fruit development of six sweet cherry varieties in Qinghai by HAO Shuaiqi, GUO Qingyun, LI Linhao, YUAN Huaning

“…[Conclusion] The six sweet cherry varieties exhibited distinct patterns in aroma compound changes during fruit development. …”
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Mental Health in the Age of Hyperconnectivity: A Crisis Hidden in Plain Sight by Sitara Ejaz, Hafiz Muhammad Haseeb Khaliq

“…Exposure to screens before bedtime reduces melatonin production by 55% (±20.1%), according to sleep specialists, which causes sleep disturbances that negatively affect both mental function and mood patterns 9.  The mental health challenges faced by young people exist far above other population groups. …”
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Experimental Research on Progressive Damage Mechanism for Water Immersed Coal Under Cyclic Loading and Unloading by WANG Fangtian, TANG Tiankuo, ZHANG Cun, DOU Fengjin, WEI Xueqian, SUN Nuan, CHENG Jiazhang

“…The strength of the coal samples decreased with the increase in water content and the number of cycles.ConclusionsThis study reveals the damage and failure mechanisms of coal subjected to hierarchical cyclic loading conditions by analyzing the acoustic emission characteristics and pore evolution patterns of coal samples with different water contents under cyclic loading…”
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Risk of developing drug abuse in administration of a new hexaazaisowurtzitane derivative-based analgesic (experimental study) by S. G. Krylova, T. N. Pove’teva, K. A. Lopatina, Yu. V. Nesterova, E. P. Zueva, O. G. Afanas’eva, P. V. Kulpin, E. A. Kiseleva, N. I. Suslov, D. A. Kulagina, S. V. Sysolyatin, V. V. Zhdanov

“…Two hours after the naloxone injection, the number of mice with negative body weight gain was determined. 24 hours after discontinuation of test compound administration, the open-field test was used to determine the impact on animal behavioral patterns (horizontal and vertical motor and exploratory activity, emotionality and its vegetative manifestations). …”
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Immunoreactivity Analysis of MHC-I Epitopes Derived from the Nucleocapsid Protein of SARS-CoV-2 via Computation and Vaccination by Dongbo Jiang, Zilu Ma, Junqi Zhang, Yubo Sun, Tianyuan Bai, Ruibo Liu, Yongkai Wang, Liang Guan, Shuaishuai Fu, Yuanjie Sun, Yuanzhe Li, Bingquan Zhou, Yulin Yang, Shuya Yang, Yuanhang Chang, Baozeng Sun, Kun Yang

“…<b>Conclusions</b>: our study revealed the general patterns among multiple haplotypes within the humans and mice superfamily, providing a comprehensive assessment of the pan-MHC-I immunoreactivity of SARS-CoV-2 NP. …”
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TWO CASES OF PRIMARY AMYLOIDOSIS PRESENTING WITH VERTEBRAL AMYLOIDOMA by Ebru Kavak Yavuz, Vehbi Demircan, Abdullah Karakus, Orhan Ayyildiz

“…It can occur in many areas of the body and is hard and fixed. This pattern of involvement is very aggressive and can cause destruction and fractures in the bone. …”
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Spectral Hardening Reveals Afterglow Emergence in Long-duration Fast X-Ray Transients: A Case Study of GRB 250404A/EP250404a by Yi-Han Iris Yin, Yuan Fang, Bin-Bin Zhang, Chen Deng, Jun Yang, Run-Chao Chen, Yuan Liu, Yehao Cheng, Dong Xu, Xiaofeng Wang, Rongfeng Shen, Rui-Zhi Li, Jirong Mao, Wen-Xiong Li, Alberto Javier Castro-Tirado, Weihua Lei, Shao-Yu Fu, Yuan-Pei Yang, Shuai-Qing Jiang, Jie An, Chun Chen, Zhong-Nan Dong, Guowang Du, Ali Esamdin, Zhou Fan, Haicheng Feng, Lu Feng, Emilio Fernández-García, Xing Gao, Maria Gritsevich, Wei-Jian Guo, Jingwei Hu, You-Dong Hu, Yanlong Hua, Abdusamatjan Iskandar, Junjie Jin, Niu Li, Xia Li, Ziwei Li, Jia-Qi Lin, Dezi Liu, Jinzhong Liu, Qichun Liu, Xiaowei Liu, Xing Liu, Daniele B. Malesani, Ignacio Pérez-García, Hui Sun, Xue-Feng Wu, Yun-Ao Xiao, Ding-Rong Xiong, Shengyu Yan, Beibei Zhang, Jinghua Zhang, Haichang Zhu, Zipei Zhu, Hu Zou, Weimin Yuan, Bing Zhang

“…This well-tracked soft–hard–flat spectral pattern provides a clear indication of afterglow emergence from the fading prompt emission and offers a practical criterion for identifying a distinct population of GRBs among fast X-ray transients, even when the detection of the gamma-ray counterpart or obvious temporal break is absent.…”
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Disrupted synaptic gene expression in Fabry disease: Findings from RNA sequencing by Laura López-Valverde, María E. Vázquez-Mosquera, Cristóbal Colón-Mejeras, J. Víctor Álvarez, Beatriz Martín López-Pardo, Lluis Lis López, Rosario Sánchez-Martínez, Manuel López-Mendoza, Mónica López-Rodríguez, Eduardo Villacorta-Argüelles, María A. Goicoechea-Diezhandino, Francisco J. Guerrero-Márquez, Saida Ortolano, Elisa Leao-Teles, Álvaro Hermida-Ameijeiras, María L. Couce

“…The objective was to identify gene expression patterns and investigate secondary cellular pathways affected by lysosomal dysfunction. …”
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Role of body anthropometry in severe asthmatic patients: Evidences from the Severe Asthma Network in Italy (SANI) registry by Erminia Ridolo, PhD, Martina Ottoni, MD, Francesca Nicoletta, MD, Francesca Locatelli, MD, Luigi Martinelli, MD, Matteo Maule, MD, Naila Arif Cheema, MD, Francesco Blasi, PhD, Pierluigi Paggiaro, MD, Enrico Heffler, PhD, Luisa Brussino, PhD, Giorgio Walter Canonica, MD, Gianenrico Senna, MD, Marco Caminati, MD, Diego Bagnasco, PhD, Cecilia Calabrese, PhD, Gianna Camiciottoli, MD, Giovanna Elisiana Carpagnano, PhD, Cristiano Caruso, MD, Angelo Guido Corsico, PhD, Maria Teresa Costantino, MD, Claudia Crimi, PhD, Alice D'Adda, MD, Simona D’Alò, MD, Maria D'Amato, PhD, Corrado D'Andria, MD, Stefano Del Giacco, MD, Fabiano Di Marco, PhD, Nicola Cosimo Facciolongo, MD, Alessandro Farsi, MD, Manuela Latorre, PhD, Manlio Milanese, PhD, Michele Mondoni, MD, Eustachio Nettis, MD, Girolamo Pelaia, MD, Laura Pini, MD, Luisa Ricciardi, PhD, Fabio Luigi Massimo Ricciardolo, PhD, Luca Richeldi, PhD, Pierachille Santus, PhD, Nicola Scichilone, PhD, Giulia Scioscia, PhD, Giuseppe Spadaro, MD, Antonio Spanevello, MD, Paolo Tarsia, MD, Mona Rita Yacoub, PhD

“…The aim of this study was to detect parameters associated with obesity in patients with severe asthma in order to check different pattern of inflammation in obese asthmatics. …”
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Improving outcomes for people with autism spectrum disorders by reducing mental health problems: the IAMHealth research programme including one RCT by Emily Simonoff, Gillian Baird, Bryony Beresford, Tony Charman, Martin Knapp, Andrew Pickles, Carol Povey, Tom Purser, Paramala Santosh, Vicky Slonims, Stephen Scott

“…Design Work package 1: we developed and validated a new instrument to provide improved detection of mental health and behavioural problems in autistic people from childhood through to adult life. …”
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Physiological and Gene Expression Responses of Crassostrea ariakensis to Salinity Stress by Miaomiao YANG, Sudong XIA, Zhihong LIU, Xiujun SUN, Liqing ZHOU, Peizhen MA, Zhuanzhuan LI, Biao WU

“…The three genes (CarHsp70, CarHyou1, and CarDANJC2) are essential for physiological functions in different shellfish tissues and may exhibit synergistic effects in response to environmental stress. Their expression patterns provide insights into the mechanisms underlying the adaptation of organisms to environmental changes. …”
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Human Action Recognition Method Based on Multi-channel Fusion by Zhiyong TAO, Xijun GUO, Xiaokui REN, Ying LIU, Zemin WANG

“…In healthcare, real-time action recognition enhances patient care, detects potential falls, and assists elderly individuals. …”
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Evaluating the effectiveness of the Drink Less smartphone app for reducing alcohol consumption compared with usual digital care: a comprehensive synopsis from a 6-month follow-up R... by Claire Garnett, Melissa Oldham, Gemma Loebenberg, Larisa Dinu, Emma Beard, Colin Angus, Robyn Burton, Matt Field, Felix Greaves, Matthew Hickman, Eileen Kaner, Susan Michie, Marcus Munafò, Elena Pizzo, Jamie Brown

“…Multiple imputation was recommended by the independent Data Monitoring Committee based on the pattern of missing data. Conclusions Drink Less appears effective for reducing alcohol consumption among increasing-and-higher-risk drinkers compared with the National Health Service alcohol advice web page in the United Kingdom, and may be cost saving if widely used in the population. …”
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A protein-based classifier for differentiating follicular thyroid adenoma and carcinoma by Yaoting Sun, He Wang, Lu Li, Jianbiao Wang, Wanyuan Chen, Li Peng, Pingping Hu, Jing Yu, Xue Cai, Nan Yao, Yan Zhou, Jiatong Wang, Yingrui Wang, Liqin Qian, Weigang Ge, Mengni Chen, Feng Yang, Zhiqiang Gui, Wei Sun, Zhihong Wang, Minghua Ge, Yi He, Guangzhi Wang, Yongfu Zhao, Huanjie Chen, Xiaohong Wu, Yuxin Du, Wenjun Wei, Fan Wu, Dingcun Luo, Xiangfeng Lin, Haitao Zheng, Xin Zhu, Bei Wei, Jiafei Shen, Jincao Yao, Zhennan Yuan, Tong Liu, Jun Pan, Yifeng Zhang, Yangfan Lv, Qiaonan Guo, Qijun Wu, Tingting Gong, Ting Chen, Shu Zheng, Jingqiang Zhu, Hanqing Liu, Chuang Chen, Hong Han, Sathiyamoorthy Selvarajan, Michael Mingzhao Xing, Kennichi Kakudo, Erik K Alexander, Yijun Wu, Yu Wang, Dong Xu, Hao Zhang, Xiu Nie, Oi Lian Kon, N Gopalakrishna Iyer, Zhiyan Liu, Yi Zhu, Haixia Guan, Tiannan Guo, We-TEC Investigators

“…Next-generation sequencing of a 66-gene panel revealed 41 (62.1%) detectable genes, while 25 were not, showing similar alteration patterns with differing mutation frequencies. …”
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Identification of genetic regulatory loci for anthocyanins in wine grape skins by WANG Shanglin, ZHANG Huimin, SUN Qi, PAN Qiuhong, DONG Zhigang, DUAN Changqing, HE Fei

“…[Results] A total of 20 anthocyanins were detected in the F1 progeny population of the CS 685 and X 100, and all anthocyanins showed a broad and continuous distribution in the cross progeny population with very high broad-sense heritability. …”
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Regional Design by Verena Balz

“…In addition, the analysis identifies patterns in the institutionalisation of regional design by the repetition of practices, adoption in formal policies and enshrinement in dedicated organisations. …”
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Eradication of Helicobacter pylori for prevention of aspirin-associated peptic ulcer bleeding in adults over 65 years: the HEAT RCT by CJ Hawkey, Anthony J Avery, Carol AC Coupland, Colin J Crooks, Jennifer S Dumbleton, FD Richard Hobbs, Denise Kendrick, Michael Moore, Clive Morris, Gregory Rubin, Murray Smith, Diane Stevenson

“…Nevertheless, the trial was able to detect a biphasic pattern of results during follow-up. …”
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Predictors of uveitic macular edema and functional prognostic outcomes: real-life data from the international AIDA Network uveitis registry by Jurgen Sota, Germán Mejía-Salgado, Silvana Guerriero, Gaafar Ragab, Gaafar Ragab, Stefania Costi, Maria Pia Paroli, Andrea Hinojosa-Azaola, Giuseppe Lopalco, Luciana Breda, Henrique Ayres Mayrink Giardini, Alex Fonollosa, Maria Sole Chimenti, Antonio Vitale, Carla Gaggiano, Blanca Aguilar-Barrera, Laura Daniela Rodríguez-Camelo, Guillermo Arturo Guaracha-Basañez, Mohamed Tharwat Hegazy, Mohamed Tharwat Hegazy, Rosanna Dammacco, Valeria Albano, Eduardo Martín-Nares, Santiago Espinosa-Lugo, Mahmoud Ghanema, Maria Morrone, Saverio La Bella, Rafael Alves Cordeiro, Francesco Carubbi, Alessandro Conforti, Piero Ruscitti, Ibrahim AlMaglouth, Rosaria Talarico, Stefano Gentileschi, Petros P. Sfikakis, Valeria Caggiano, Matteo Piga, Adele Civino, Francesca Ricci, Maissa Thabet, Marcello Govoni, Abdurrahman Tufan, Francesca Crisafulli, Jessica Sbalchiero, Sulaiman M. Al-Mayouf, Angela Mauro, Angela Mauro, Soad Hashad, Soad Hashad, Francesca Minoia, Alma Nunzia Olivieri, Samar Tharwat, Samar Tharwat, Maria Cristina Maggio, Abdelhfeez Moshrif, Gian Domenico Sebastiani, Daniela Opris-Belinski, Gülen Hatemi, Gülen Hatemi, Haner Direskeneli, Fatma Alibaz-Öner, Lampros Fotis, José Hernández-Rodríguez, Giovanni Conti, Piercarlo Sarzi Puttini, Ombretta Viapiana, Annarita Giardina, Patrizia Barone, Kalpana Babu, Rana Hussein Amin, Perla Ayumi Kawakami-Campos, Vishali Gupta, Annamaria Iagnocco, Ali Şahin, Antonella Insalaco, Andrés González-García, Ezgi Deniz Batu, Ester Carreño, Emanuela Del Giudice, Cecilia Beatrice Chighizola, Cecilia Beatrice Chighizola, Fabrizio Conti, Alberto Balistreri, Bruno Frediani, Luca Cantarini, Alejandra de-la-Torre, Claudia Fabiani

“…ObjectivesTo detect factors capable of predicting the development of macular edema (ME) throughout the disease course in patients affected by non-infectious uveitis (NIU).MethodsPredictive factors leading to the development of ME were analyzed through regression analysis. …”
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