Global insights into the genome dynamics of Clostridioides difficile associated with antimicrobial resistance, virulence, and genomic adaptations among clonal lineages by Mohammad Sholeh, Mohammad Sholeh, Masoumeh Beig, Masoumeh Beig, Ebrahim Kouhsari, Mahdi Rohani, Mohammad Katouli, Farzad Badmasti

“…Antibiotic resistance genes, virulence factors, and toxins were detected using the CARD and VFDB databases, and the ABRicate software. …”
Get full text

Cross-language orthographic neighborhood density effects in Dutch–English and Spanish–English bilinguals by Britta Biedermann, Britta Biedermann, Elisabeth Beyersmann, Mara Blosfelds, Christella Macapagal, Ashleigh Rosevear, Welber Marinovic

“…Instead, we found a significant interaction between English (L2) and Spanish (L1) ND. Reaction time patterns were confirmed by the non-parametric analysis, although with only a marginally significant interaction. …”
Get full text

Single nucleotide polymorphisms, gene expression and evaluation of immunological, antioxidant, and pathological parameters associated with bacterial pneumonia in Barki sheep by Ahmed El Sayed, Amani Hafez, Ahmed Ateya, Asmaa Darwish, Amin Tahoun

“…Conclusions This study revealed the significant presence of various pathogens and virulence factors in infected sheep, along with distinct immunological and antioxidant gene expression patterns. The altered serum profile and gene regulation in pneumonia-affected ewes underscore the complex immune response and potential biomarkers for disease susceptibility and resistance.…”
Get full text

Genomic Characterization and Antimicrobial Resistance of ESBL-Producing, Escherichia coli Isolates in Suzhou, China by Wang C, Zhang H, Zhao R, Tsui CKM, Deng S

“…In addition, genes associated with resistance to fluoroquinolone, aminoglycosides, and sulfonamides were also detected.Conclusion: Our findings highlighted the prevalence of globally circulating ESBL-producing E. coli clones, such as ST131 and ST1193, in Suzhou, China. …”
Get full text

Expression of degenerative markers in intervertebral discs of young and elderly asymptomatic individuals. by Josemberg S Baptista, Vincent C Traynelis, Edson A Liberti, Ricardo B V Fontes

“…Expression of remodeling enzymes and inflammatory mediators is relatively similar across different vertebral segments and disc regions leading to a common degenerated pattern, while neurotrophins have slightly higher expression in cervical discs. …”
Get full text

Real-time intestinal perfusion assessment for anastomotic site selection using laser speckle contrast imaging: Verification in a porcine model by Danique J.I. Heuvelings, Mahdi Al-Taher, Joost Calon, Manish Chand, Laurents P.S. Stassen, Tim Lubbers, Kevin P. Wevers, Luigi Boni, Nicole D. Bouvy, Wido Heeman

“…The questionnaire revealed that the senior surgeons were satisfied with the perfusion imager, particularly in terms of minimal latency, ease of use and set up, and ability to accurately represent blood flow patterns as these questions showed a (very) strong agreement in 80 %. …”
Get full text

Genotype-dependent response to water deficit: increases in maize cell wall digestibility occurs through reducing both p-coumaric acid and lignification of the rind by Ana López-Malvar, Ana López-Malvar, Oscar Main, Oscar Main, Sophie Guillaume, Marie-Pierre Jacquemot, Florence Meunier, Pedro Revilla, Rogelio Santiago, Valerie Mechin, Valerie Mechin, Matthieu Reymond

“…In terms of in vitro cell wall digestibility (IVCWRD), significant increases were detected in response to water deficit. Additionally, genotype-dependent response patterns were evident, revealing two distinct behavioural groups. …”
Get full text

The arrow of time in Parkinson’s disease by Fatemeh Sadeghi, Elvira del Agua Banyeres, Alessandra Pizzuti, Abdullah Okar, Kai Grimm, Christian Gerloff, Morten L. Kringelbach, Rainer Goebel, Simone Zittel, Gustavo Deco

“…Results: We found that PD is characterized by disrupted equilibrium regimes, marked by distinct effective connectivity patterns, particularly within the motor networks. Additionally, we observed a flatter hierarchical organization in PD, with the cerebellum and thalamus exerting increased influence. …”
Get full text

Uncovering the breeding contribution of transposable elements from landraces to improved varieties through pan-genome-wide analysis in rice by Xiaoxia Li, Xiaoxia Li, Xiaofan Dai, Xiaofan Dai, Huiying He, Wu Chen, Qian Qian, Qian Qian, Lianguang Shang, Lianguang Shang, Longbiao Guo, Wenchuang He

“…Comparing landraces and improved varieties, 4,334 selective TEs were detected within or near 3,070 genes that were enriched in basic metabolism and development and stress resistance. …”
Get full text

Epidemiological insights into canine rabies in Chennai: Trends, forecasting and One Health implications by Viswanathan Naveenkumar, Mangalanathan Vijaya Bharathi, Porteen Kannan, B.S. Pradeep Nag, Sureshkannan Sundaram, Nithya Quintoil Mohanadasse, Raghavendra G. Amachawadi, Muskan Dubey, Charley A. Cull, Chandan Shivamallu, Shiva Prasad Kollur, Ravindra P. Veeranna

“…This study provides epidemiological insights into canine rabies in Chennai, analyzing nine years of surveillance data (n = 428, March 2010 – February 2019) to assess trends, seasonality and predictive patterns. Change point and time series analyses were conducted and forecasting models were evaluated using Root Mean Squared Error (RMSE), Mean Absolute Error (MAE), Mean Absolute Percentage Error (MAPE) and Mean Absolute Scaled Error (MASE) metrics. …”
Get full text

Whole Genome Sequencing of Carbapenem-Resistant Pseudomonas aeruginosa from Clinical and Screening Samples in Indonesia by Selvi N. Shahab, Anneloes Van Veen, Corné H.W. Klaasen, Jeff Gauthier, Irena Kukavica Ibrulj, Marianne Potvin, Guillaume Q.H. Nguyen, Yulia R. Saharman, Anis Karuniawati, Margreet Vos, Roger C. Lévesque, Juliëtte A. Severin

“…Antimicrobial susceptibility patterns were diverse, with high rates of resistance to multiple antibiotics (Table 1-2). …”
Get full text

An AI recognition method for children's clinical operative pain by skin potential (SP) signal by Mingxuan Huang, Cangcang Fu, Linbo Chui, Jiadong He, Xiaozhi Wang, Jikui Luo, Bin Wu, Yonggang Chen, Shaohua Hu, Jihua Zhu, Yubo Li

“…Objective and rationale: Children's clinical pain phenotypes are complex, and there is a lack of objective biological diagnostic markers and cognitive patterns. Detecting physiological signals through wearable devices simplifies disease diagnosis and holds the potential for remote medical applications. …”
Get full text

Correlation between abnormal posture, screen time, physical activity, and suspected scoliosis: a cross-sectional study by Hongxin Chen, Liyang Wu, Yi Zhang, Jinyi Liu, Rui Huang, Jinyang Xie, Zhenfeng Guo, Tao Huang, Cuiling Chen, Kaimin Yang, Yuying Bai, Xuanxuan Huang, Zhuopeng Zhang, Ruike Zhang

“…Moreover, a marked correlation exists between distinct activity patterns, particularly extended usage of electronic devices and television, and the incidence of suspected scoliosis. …”
Get full text

Exposure assessment for air-to-skin uptake of traditional and emerging organophosphate flame retardants by Yujuan Fan, Ran Qi, Sicong Dong, Jing Zhang, Shiyu Shi, Youhua Zhao, Pengkun Wei, Guangxuan Yan, Ke Cheng, Huanjia Liu, Dan Yao, Chen Chen, Zhiguo Cao

“…Removal of the OPFRs with consecutive tape strips demonstrated that OPFRs diffusion through the skin exhibited declining concentration patterns with depth. A diffusion model was applied to the surface skin to simulate the OPFR concentration profiles and was compared with measured concentrations. …”
Get full text

Fine Structures of Radio Bursts from Flare Star AD Leo with FAST Observations by Jiale Zhang, Hui Tian, Philippe Zarka, Corentin K. Louis, Hongpeng Lu, Dongyang Gao, Xiaohui Sun, Sijie Yu, Bin Chen, Xin Cheng, Ke Wang

“…Sub-bursts on the second day, however, reveal a different blob-like shape with random occurrence patterns and are akin to solar radio spikes. The new observational results suggest that the intense emission from AD Leo is driven by electron cyclotron maser instability, which may be related to stellar flares or interactions with a planetary companion.…”
Get full text

Vestibular Atelectasis: A Narrative Review and Our Experience by Andrea Tozzi, Andrea Castellucci, Salvatore Martellucci, Pasquale Malara, Michael Eliezer, Giuseppe Ferrulli, Rosanna Rita Ruberto, Pasquale Brizzi, Enrico Armato, Alessio Marchetti, Daniele Marchioni, Angelo Ghidini, Claudio Moratti

“…While specific radiological patterns consistent with VA have been described on contrast-enhanced MRI with delayed acquisitions, an impairment of the blood–labyrinthine barrier (BLB) could be detected in several disorders leading to vestibular loss. …”
Get full text

The diagnostic utility of lung ultrasound in the assessment of interstitial lung disease associated with rheumatoid arthritis by Shaoyu Zheng, Zexuan Zhou, Guangzhou Du, Qingzi Chen, Shaoqi Chen, Jianqun Lin, Shijian Hu, Weijin Zhang, Kedi Zheng, Jinghua Zhuang, Meigan Huang, Barbara Ruaro, Cosimo Bruni, Anna-Maria Hoffmann-Vold, Marco Matucci-Cerinic, Daniel E. Furst, Yukai Wang

“…A positive judgement was given on LUS when the B-lines score exceeded 10. The presence and patterns of ILD were defined by HRCT findings. ROC curve analysis was used to calculate the accuracy of LUS to detect ILD. …”
Get full text

Pathological and clinical insights into DICER1 hotspot mutated Sertoli-Leydig cell tumors: a comparative analysis by Zhuoyao Lyu, Yilin Liu, Jingci Chen, Pengyan Wang, Zhaohui Lu, Xiaoyan Chang, Xianlong Chen, Heng Ma, Shengwei Mo, Shuangni Yu, Jie Chen

“…DICER1 RNase IIIb hotspot mutations were detected by the Sanger sequence. Clinical information, such as patients' symptoms, tumor staging, prognosis, and pathological features, such as tumor differentiation and growth patterns, were collected. …”
Get full text

Emaciated enigma: Decline in body conditions of common dolphins in the Celtic Seas ecoregion by Sofia Albrecht, Cóilín Minto, Emer Rogan, Rob Deaville, Jim O'Donovan, Mags Daly, Stephanie Levesque, Simon Berrow, Andrew Brownlow, Nicholas J. Davison, Orla Slattery, Luca Mirimin, Sinéad Murphy

“…Both significant temporal and seasonal patterns in VBT were identified, with poorer body conditions observed during the autumn and better body conditions observed during the spring, as well as an overall decline detected in VBT during the study period. …”
Get full text

Development and validation of hierarchical signature for precision individualized therapy based on the landscape associated with necroptosis in clear cell renal cell carcinoma by Gao-Sheng Yao, Jun-Shang Dai, Jun-Shang Dai, Liang-Min Fu, Liang-Min Fu, Juan Lin, Zhi-Ping Tan, Lei Dai, Wei Chen, Jun-Hang Luo, Jun-Hang Luo, Jin-Huan Wei

“…Here, we systematically evaluate the role of necroptosis in clear cell renal cell carcinoma (ccRCC) and analyze its regulatory patterns.MethodsFirst, we evaluated the expression and enrichment of necroptotic factors in ccRCC using gene set enrichment analysis (GSEA) and survival analysis in the expression profile from The Cancer Genome Atlas (TCGA) to demonstrate the overall mutation of necroptotic pathway genes. …”
Get full text