Multidisciplinary Delphi consensus on challenges and key factors for an optimal care model in chronic kidney disease by José Luis Górriz, Roberto Alcázar Arroyo, Patricia Arribas, Sara Artola, Sergio Cinza-Sanjurjo, Rafael de la Espriella, Javier Escalada, Lisardo García-Matarín, Luis Martínez, Juan Carlos Julián, José Pablo Miramontes-González, Félix Rubial, Mercedes Salgueira, María José Soler, José Luis Trillo

“…The purpose of this study was to analyse the care patterns for these patients and to reach a consensus on the key factors that should be implemented for an optimal care model in CKD, through a multidisciplinary and integrative vision. …”
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Hemodialysis Procedure–Associated Autonomic Imbalance and Cardiac Arrhythmias: Insights From Continuous 14‐Day ECG Monitoring by Nichole M. Rogovoy, Stacey J. Howell, Tiffany L. Lee, Christopher Hamilton, Erick A. Perez‐Alday, Muammar M. Kabir, Yanwei Zhang, Esther D. Kim, Jessica Fitzpatrick, Jose M. Monroy‐Trujillo, Michelle M. Estrella, Stephen M. Sozio, Bernard G. Jaar, Rulan S. Parekh, Larisa G. Tereshchenko

“…During every‐other‐day dialysis, root mean square of the successive normal‐to‐normal intervals had a significant circadian pattern (Mesor 10.6 [ 95% CI 0.9–11.2] ms; amplitude 1.5 [95% CI 1.0–3.1] ms; peak at 02:01 [95% CI 20:22–03:16] am; P<0.0001), which was replaced by a steady worsening on the second day without dialysis (root mean square of the successive normal‐to‐normal intervals −1.41 [95% CI −1.67 to −1.15] ms/24 h; P<0.0001). …”
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Systemic immune inflammation index and systemic inflammation response index predict frailty progression in older patients undergoing elective orthopedic surgery by Guanghan Gao, Zitian Zheng, Fei Wang, Yaonan Zhang, Lei Shi, Lin Wang, Hongyu Wang, Qingyun Xue

“…The linear trend between SII–SIRI pattern/SII/SIRI levels and frailty progression was statistically significant. …”
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Outcomes of Suprapatellar Intramedullary Nail Fixation of Tibial Shaft Fractures in Skeletally Immature Patients by Carlos D. Pargas-Colina, MD, Tori J. Coble, DO, Sara E. Davis, BS, David D. Spence, MD, Jonathan K. Rowland, BS, Derek M. Kelly, MD, Benjamin W. Sheffer, MD

“…The most common (57%) fracture pattern was OA42A1-3. Fracture union occurred by 9 weeks in 79% of cases. …”
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RECIST 1.1 AND irRC FOR RESPONSE ASSESMENT IN PATIENTS WITH DISSEMINATED CUTANEOUS MELANOMA TREATED WITH IPILIMUMAB OR DENDRITIC CELL VACCINE by A. V. Novik, E. V. Yaremenko, E. M. Anokhina, T. L. Nehaeva, A. I. Semenova, D. Kh. Latipova, S. A. Protsenko, I. A. Baldueva

“…In the DCV group the same pattern wasn’t found. Thus, both the RECIST 1.1 system and the irRC system are good surrogate markers for the overall survival. …”
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PHENOTYPIC FEATURES OF ENDOMETRIAL CANCER AND MSI IN COLON AND BLOOD SERUM by S. M. Kartashov, E. M. Oleshko

“…Analysis of MSI occurrence frequency in case of EC showed that MSI is significantly more frequently observed in blood serum (10.8 % of cases) than in the colonic tissue (mucosal lining) (6.1 %). A similar pattern was observed also in cases with MSI+ tumour phenotype (MSI frequency in colonic mucosal lining made 12.2 %, whereas in blood serum – 29.6 %, p <0.01). …”
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Bounce effect or local recurrence after low-dose-rate brachytherapy of the prostate? When prostate-specific membrane antigen positron emission tomography–computed tomography is fal... by Tamas Rozsos, Daniel S. Engeler, Hans-Peter Schmid, Christoph Schwab

“…However, a routine prostate-specific antigen screening before initiating salvage radiotherapy revealed a decrease to 3.75 µg/l with an additional reduction to 2.68 µg/l at 2 months later. The pattern of transient prostate-specific antigen elevation strongly suggested a bounce phenomenon rather than a recurrence, allowing any unnecessary treatment to be avoided. …”
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Coevolution of the Ile1,016 and Cys1,534 Mutations in the Voltage Gated Sodium Channel Gene of Aedes aegypti in Mexico. by Farah Z Vera-Maloof, Karla Saavedra-Rodriguez, Armando E Elizondo-Quiroga, Saul Lozano-Fuentes, William C Black Iv

“…Ile1,016 in S6 of domain II then arose from the Val1,016/Cys1,534 haplotype and was rapidly selected because double mutants confer higher pyrethroid resistance. This pattern suggests that knowledge of the frequencies of mutations in both S6 in domains II and III are important to predict the potential of a population to evolve kdr. …”
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CARDIOVASCULAR DISEASES OF THE LENINGRAD SIEGE SURVIVORS - NEW RISK FACTORS RESEARCH by M. P. Rotar, E. V. Moguchaya, E. P. Kolesova, M. A. Boyarinova, A. M. Erina, E. A. Dudorova, M. A. Ilyina, V. N. Solntsev, A. O. Konradi

“…In the control group were 46 patients with similar gender and age pattern — 31 (67%) females and 15 (33%) males, mean age was 71,3 years. …”
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A case report of a spherical mass in the right atrium: myxoma or thrombus? by Yulian Wu, Xidan Wang, Daoling Yang, Xiaoying Tao

“…A spherical mass was incidentally detected in the right atrium during a routine examination. …”
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Comprehensive overview of genotype distribution and prevalence of human papillomavirus in cervical lesions by Yang Liu, Chengquan Zhao, Tiannan Wang, Yuhong Ye, Terrel Jones, Xianxu Zeng

“…Women with atypical glandular cell (AGC) Pap test results showed a specific HPV genotyping pattern and extended HPV genotyping may be helpful for the clinical management of AGCs. …”
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Meta-analysis of acupuncture combined therapies for amblyopia: efficacy and safety insights by Kang Tan, Kang Tan, Yunfeng Yu, Pei Liu, Pengfei Jiang, Yi Liu, Bidan Lou, Qinghua Peng

“…The meta-analysis demonstrated that, compared with to the conventional treatment, the acupuncture combined with conventional treatment significantly improved the clinical efficacy rate (relative risk [RR] 1.31, 95% confidence interval [CI] 1.21–1.43, P &lt; 0.00001, GRADE: low), the best-corrected visual acuity (BCVA) [mean difference (MD) 0.08, 95% CI 0.01–0.15, P = 0.03, GRADE: very low], and the amplitude of pattern visual evoked potential (P-VEP) P100 wave (MD 3.24, 95% CI 1.42–5.05, P = 0.0005, GRADE: low), while reduced the stereoacuity (MD −3.59, 95% CI −5.97 to 1.20, P = 0.003, GRADE: very low) and the latency of P-VEP P100 wave (MD −7.44, 95% CI −11.71 to −3.18, P = 0.0006, GRADE: very low). …”
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LEVELS I–VII FOLLOWING THYROIDECTOMY FOR PAPILLARY THYROID CANCER by V. S. Parshin, A. A. Veselova, V. S. Medvedev, S. A. Ivanov, A. D. Kaprin

“…The predominant metastatic pattern was solitary. There was an essential difference in metastatic spread to cervical lymph nodes between postthyroidectomy patients and patients who were first diagnosed with papillary thyroid cancer.…”
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Canopy Chlorophyll Content Inversion of Mountainous Heterogeneous Grasslands Based on the Synergy of Ground Hyperspectral and Sentinel-2 Data: A New Vegetation Index Approach by Yi Zheng, Yao Wang, Tayir Aziz, Ali Mamtimin, Yang Li, Yan Liu

“…The results indicated the following: (1) DRECAVI demonstrated the highest accuracy in CCC retrieval for mountainous vegetation (R² = 0.74, RMSE = 16.79, MAE = 12.50) compared to other VIs and hybrid methods, effectively mitigating saturation effects in high biomass areas and capturing a weak bimodal distribution pattern of CCC in the montane meadow. (2) The blue band B1 enhances atmospheric correction robustness by suppressing aerosol scattering, and the red-edge band B7 overcomes the sensitivity limitations of conventional red-edge indices (such as NDVI705, CIred-edge, and NDRE), demonstrating the potential application of the synergy mechanism between the blue band and the red-edge band. (3) Although the S2BP achieved high accuracy (R² = 0.73, RMSE = 19.83, MAE = 14.71) without saturation effects and detected a bimodal distribution of CCC in the montane meadow of the study area, its algorithmic complexity hindered large-scale operational applications. …”
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Distribution of cold and temperate ice in glaciers on the Nordenskiold Land, Spitsbergen, from ground-based radio-echo sounding by Yu. Ya. Macheret, A. F. Glazovsky, I. I. Lavrentiev, I. O. Marchuk

“…Data presented in this paper demonstrate more sophisticated pattern of the cold and temperate ice distribution within the glaciers than it was earlier known that should be taken into consideration when modeling and forecasting dynamics of the polythermal glaciers and investigating internal processes of the temperate ice formation in such glaciers.…”
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Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants. by Catherine Riou, Jinal N Bhiman, Yashica Ganga, Shobna Sawry, Frances Ayres, Richard Baguma, Sashkia R Balla, Ntombi Benede, Mallory Bernstein, Asiphe S Besethi, Sandile Cele, Carol Crowther, Mrinmayee Dhar, Sohair Geyer, Katherine Gill, Alba Grifoni, Tandile Hermanus, Haajira Kaldine, Roanne S Keeton, Prudence Kgagudi, Khadija Khan, Erica Lazarus, Jean Le Roux, Gila Lustig, Mashudu Madzivhandila, Siyabulela F J Magugu, Zanele Makhado, Nelia P Manamela, Qiniso Mkhize, Paballo Mosala, Thopisang P Motlou, Hygon Mutavhatsindi, Nonkululeko B Mzindle, Anusha Nana, Rofhiwa Nesamari, Amkele Ngomti, Anathi A Nkayi, Thandeka P Nkosi, Millicent A Omondi, Ravindre Panchia, Faeezah Patel, Alessandro Sette, Upasna Singh, Strauss van Graan, Elizabeth M Venter, Avril Walters, Thandeka Moyo-Gwete, Simone I Richardson, Nigel Garrett, Helen Rees, Linda-Gail Bekker, Glenda Gray, Wendy A Burgers, Alex Sigal, Penny L Moore, Lee Fairlie

“…T-cell responses followed a similar pattern to neutralizing antibodies. Six months post-boost, antibody and T-cell responses had waned to baseline levels. …”
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High expression of DGKA indicates poor overall survival of nasopharyngeal carcinoma by Hao Chen, Runduan Lin, Qi Yuan, Xiaohang Gao, Lin Zhang, Rong Zhang

“…The aim of this study is to investigate the expression patterns and prognostic value of DGKA in NPC. Methods The mRNA expression of DGKA was analyzed from the dataset of The Cancer Genome Atlas (TCGA). …”
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High genetic diversity yet weak population genetic structure in European common terns by Veronika Lončar, Jelena Kralj, Astrid Vik Stronen, Marija Grgurević, Željko Pavlinec, Luka Jurinović, Ida Svetličić, Elena Buzan, Simon Piro, Christof Herrmann, Iztok Škornik, Davorin Tome, Gyula Kovács, Bálint Preiszner, Péter Szinai, Stefano Volponi, Sunčica Stipoljev, Ana Galov

“…The low genetic differentiation is likely influenced by distinct migration patterns, particularly between Southern Inland and Marine groups. …”
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Comparative analysis of galectin-1, galectin-3, and galectin-8 signatures in normal and choriocarcinoma trophoblast cell lines by Jovanović Krivokuća Milica, Legner Janko, Ćujić Danica, Vilotić Aleksandra, Grubiša Ivana, Vićovac Ljiljana, Bojić-Trbojević Žanka

“…These findings highlight variations in the expression, staining patterns, and subcellular distribution of galectins -1, -3, and -8, suggesting their potential involvement in the pathology of choriocarcinoma.…”
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Discovery of candidate functional non-coding mutations in acute myeloid leukemia using single-cell chromatin accessibility sequencing by Ming Zhu, Jiali Zhu, Zhijuan Zhu, Yiding Yang, Jinxian Dai, Hua Li, Nainong Li, Jialiang Huang

“…Additionally, we develop eMut, an integrated computational pipeline for detecting, imputing, and functionally characterizing non-coding mutations in CREs at the single-cell level. …”
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