Young-Onset Amyotrophic Lateral Sclerosis: Genetic Structure and Phenotypic Features by Denis V. Shevchuk, Natalya Yu. Abramycheva, Arina R. Protsenko, Darya A. Grishinа, Angelina G. Makarova, Maria N. Zakharova

“…Early identification of both sporadic and familial forms of yALS and determination of their molecular genetic patterns is critical for timely genetic counseling and identification of potentially treatable etiologies.…”
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Depth Gradient and Radon Activity Concentration in Soil Gas in the Zone of a Potentially Active Fault by Timofey Leshukov, Konstantin Legoshchin, Kirill Avdeev, Elizaveta Baranova, Aleksey Larionov

“…Radon activity concentration was measured in 0.6 m, 1 m and 1.5 m boreholes, and the depth gradient was also calculated. Spatial patterns were estimated using an autocorrelation index. …”
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Antimicrobial resistance and virulence in Klebsiella pneumoniae: a four-month study in Osogbo, Nigeria by Taofikat Olatundun Akintoyese, Jude Oluwapelumi Alao, Elijah Kolawole Oladipo, Omolanke Temitope Oyedemi, Olubukola Monisola Oyawoye

“…Molecular characterization revealed the presence of virulence genes K1, K2, and mrkD in 15 isolates, while other tested virulence genes (fimH, ramA, traT, K3, and K5) were not detected. Significant associations were identified between resistance patterns and demographic factors, including age and sex, highlighting potential vulnerabilities in specific populations. …”
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PROGNOSTIC SIGNIFICANCE OF nm23 PROTEIN IN THE TUMORS OF PATIENTS WITH COLORECTAL CANCER by D. A. Golovkov, I. P. Moshurov, V. V. Delektorskaya, D. V. Sukhoverkov, M. B. Bykovtsev, R. I. Moshurov, L. O. Petrov

“…In nmtastasis of CRC the main patterns of expression of a marker characteristic of the corresponding primary tumors was preserved. …”
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Mineral Content of Four Mexican Edible Flowers Growing in Natural Conditions and Backyards from Indigenous Communities by Rubí Marcos-Gómez, Araceli M. Vera-Guzmán, Mónica L. Pérez-Ochoa, Laura Martínez-Martínez, Sanjuana Hernández-Delgado, David Martínez-Sánchez, José L. Chávez-Servia

“…The macro- and microelement patterns range from highest to lowest concentrations were as follows: K > Ca ≥ P > Mg > S > Na and Si > Fe ≥ Zn > Mn > Cu > Mo. …”
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Epitranscriptomic analysis reveals clinical and molecular signatures in glioblastoma by Glaucia Maria de Mendonça Fernandes, Wesley Wang, Saman Seyed Ahmadian, Daniel Jones, Jing Peng, Pierre Giglio, Monica Venere, José Javier Otero

“…Novel differences in N6-Methyladenosine (m6A) RNA methylation patterns between these groups are identified in the first biopsy. …”
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Integration of Machine Learning and Wavelet Algorithms for Processing Probing Signals: An Example of Oil Wells by Zukhra Abdiakhmetova, Zhanerke Temirbekova

“…By integrating wavelet-based feature extraction with machine learning-driven analysis, this approach enhances the ability to detect complex wave propagation patterns, leading to more precise subsurface modeling. …”
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Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry. by Michael J Kluk, Todd Ashworth, Hongfang Wang, Birgit Knoechel, Emily F Mason, Elizabeth A Morgan, David Dorfman, Geraldine Pinkus, Oliver Weigert, Jason L Hornick, Lucian R Chirieac, Michelle Hirsch, David J Oh, Andrew P South, Irene M Leigh, Celine Pourreyron, Andrew J Cassidy, Daniel J Deangelo, David M Weinstock, Ian E Krop, Deborah Dillon, Jane E Brock, Alexander J F Lazar, Myron Peto, Raymond J Cho, Alexander Stoeck, Brian B Haines, Sriram Sathayanrayanan, Scott Rodig, Jon C Aster

“…Following validation using xenografted cancers and normal tissues with known patterns of NOTCH1 activation, we applied this test to tumors linked to dysregulated Notch signaling by mutational studies. …”
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Long-term β-cells autoimmune destruction markers persistence and residual C-peptide secretion in type 1 diabetes mellitus by M. R. Ragimov, O. S. Derevyanko, N. M. Malysheva, Z. T. Zuraeva, L. V. Nikankina, T. V. Nikonova

“…Ab to glutamic acid decarboxylase (GADA), tyrosine phosphatase-like IA-2 (IA2) and zinc T8 (ZnT8A) were detected by Enzyme Immunoassay. Also detected C-peptide levels and retrospectively HbA1с.Results: Antibodies to antigens of β-cell components were detected in 26 (37%) patients in group A, in 17 patients (33%) in group B, in 15 (29%) in group C and in 14 (23%) — G.In the control group (n = 19), an increased level of antibodies was not revealed. …”
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Correlation Between Pathological and MRI Radiological Tumor Responses to Neoadjuvant Chemotherapy in Non‐Luminal Breast Cancer: A Single Institution Experience by Wesal M. Eldehna, Fawzy Elbarbry, Abdul Hameed Hassan, Rafat Abu Shakra, Ahmed Elaryan, Ola Mousa Abdelfattah Elnady, Elshaimaa Mohamed Mohamed

“…So, the high correlation between measurements of residual disease detected by MRI and those detected by pathological assessment supports the use of MRI for imaging assessment during NACT. …”
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Functional analysis of heterozygous variants in the SALL1 gene in 2 children with Townes-Brocks syndrome with FSGS by Rong Liang, Bixia Zheng, Chunli Wang, Sanlong Zhao, Wei Zhou, Ying Chen, Ruochen Che

“…Immunofluorescence analysis revealed aberrant localization patterns for both SALL1 variants within podocytes. …”
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Combined semiquantitative nail-enthesis complex ultrasonography and capillaroscopy in psoriasis and psoriatic arthritis by Giacomo Cafaro, Roberto Bursi, Valentina Valentini, Katharina Hansel, Carlo Perricone, Vincenzo Venerito, Onelia Bistoni, Manuela Sebastiano, Fabiana Topini, Luca Stingeni, Roberto Gerli, Elena Bartoloni

“…Unsupervised clustering models and factor analysis were employed to identify patterns and interrelationships between US and NVC parameters. …”
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Factors affecting survival of adult female white‐tailed deer after coyote establishment in south Carolina by John C. Kilgo, Mark Vukovich, Michael J. Conroy, H. Scott Ray, Charles Ruth

“…The best model describing survival patterns included only month, with survival being lowest during November–December, which coincided with hunting season. …”
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Analysis of meteorological drought using satellite-based rainfall products over southern Ethiopia by T. M. Weldegerima, T. B. Gebresilassie, T. B. Gebresilassie

“…Hence, the CHIRPS-based satellite rainfall product was used to assess the spatio-temporal patterns of meteorological drought based on the 3-month and 12-month standardized precipitation index (SPI). …”
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Synchronous field measurement of high energy sand saltation on typical desert surfaces, Alxa plateau by Yu Gu, Yong Liu, Peijun Shi, Guoming Zhang, Yanyan Yang, Guangpeng Wang, Ziying Hu, Lianyou Liu

“…Abstract Investigating aeolian saltation over typical desert surfaces is crucial for understanding aeolian patterns and geomorphic development in arid and semi-arid regions. …”
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Novel Crushing Technique for Measuring δ18O and δ2H Values of Fluid Inclusions (H2O) in Quartz Mineral Veins Using Cavity Ring-Down Spectroscopy by Akbar Aydin Oglu Huseynov, H. J. L. van der Lubbe (Jeroen), S. J. A. Verdegaal-Warmerdam, Onno Postma, Julian Schröder, Hubert Vonhof

“…The results from single and sequential mechanical crushing, together with interlaboratory comparisons, exhibit reliable and consistent isotopic patterns across locations with high precision (for δ18O: 1σ SD<0.8‰; for δ2H: 1σ SD<1.5‰). …”
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Spatial Gap-Filling of Himawari-8 Hourly AOD Products Using Machine Learning with Model-Based AOD and Meteorological Data: A Focus on the Korean Peninsula by Youjeong Youn, Seoyeon Kim, Seung Hee Kim, Yangwon Lee

“…Furthermore, the gap-filled dataset successfully captured seasonal AOD patterns, with values ranging from 0.245–0.300 in winter to 0.381–0.391 in summer, providing a comprehensive view of aerosol dynamics across South Korea.…”
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Assessment of Oculomotor Functions as a Biomarker in Mild Traumatic Brain Injury by Ekaterina Lunkova, Jen-Kai Chen, Rajeet Singh Saluja, Alain Ptito

“…Key findings include the following: (1) oculomotor deficits in concussed subjects compared with controls, (2) abnormal activation patterns in areas related to the regulation and control of oculomotor movements, suggesting concussion-induced disruptions, and (3) the potential of oculomotor assessment as a promising approach for mTBI biomarkers, with anti-saccades and OKN identified as the most sensitive tasks.…”
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Cardiac Magnetic Resonance Imaging Findings in Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitides: A Systematic Review by Ioannis Karageorgiou, Unnati Bhatia, Hazem Alakhras, Berk Celik, Alexandra Halalau

“…Conclusion This systematic review reveals a high prevalence of myocardial fibrosis detected by cMRI in patients with AAV, even during remission. …”
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RNA Splicing Aberrations in Hereditary Cancer: Insights from Turkish Patients by Seda Kilic, Ozge Sukruoglu Erdogan, Seref Bugra Tuncer, Betul Celik Demirbas, Zubeyde Yalniz Kayim, Hulya Yazici

“…Through functional studies, this study sought to examine the potential impact of seven variants within six inherited cancer-related genes on RNA splicing patterns in Turkish cancer patients. Upon detecting variants using Next-Generation Sequencing (NGS), we used Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) and Sanger sequencing to elucidate the effects of these variants on splicing. …”
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