Using iDNA to determine impacts of Amazonian deforestation on Leishmania hosts, vectors, and their interactions. by Aimee L Massey, David José Ferreira da Silva, Carla Julia da Silva Pessoa Vieira, Jennifer M Allen, Gustavo Rodrigues Canale, Christine Steiner São Bernardo, Roberta Vieira de Morais Bronzoni, Carlos A Peres, Taal Levi

“…We collected sandflies and carrion flies at forest sites across a deforestation gradient in the southern Amazon 'Arc of Deforestation', which exemplifies global patterns of deforestation due to agricultural expansion. …”
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Restricted mean survival time approach versus time-varying coefficient Cox model for quantifying treatment effect when hazards are non-proportional by Tianyuan Gu, Zhaojin Chen, Yu Yang Soon, Joseph Wee, Bee-Choo Tai

“…The survival time t was assumed to follow the Piecewise Exponential distribution with various censoring patterns generated from the Uniform distribution. Both methods were evaluated via a randomised clinical trial of nasopharyngeal cancer exhibiting increasing treatment benefit. …”
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Characterisation of the wildlife reservoir community for human and animal trypanosomiasis in the Luangwa Valley, Zambia. by Neil E Anderson, Joseph Mubanga, Eric M Fevre, Kim Picozzi, Mark C Eisler, Robert Thomas, Susan C Welburn

“…Consistent land use patterns over the last century have resulted in epidemiological stability, but this may be threatened by the recent influx of people and domesticated livestock into the mid-Luangwa Valley.…”
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Molecular mechanism of DdSOC1 gene regulating flower bud initiation in Diospyros deyangensis by WAN Jianqi, DING Yu, REN Han, LI Wenxia, YANG Yong, HUANG Jinmeng, GUAN Changfei

“…The function of the DdSOC1 gene in controlling flower bud initiation in D. deyangensis was investigated, along with its sequence characterization and expression pattern. [Methods] Plant materials were obtained from Nicotiana tabacum and 1-and 2-year-old persimmon (D. deyangensis) seedlings cultivated in the orchard at Northwest A&F University under natural conditions. …”
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The impact of hypercortisolism beyond metabolic syndrome on left ventricular performance: a myocardial work analysis by Floran Sahiti, Mario Detomas, Vladimir Cejka, Kristina Hoffmann, Götz Gelbrich, Stefan Frantz, Mathias Kroiss, Peter U. Heuschmann, Stefanie Hahner, Martin Fassnacht, Timo Deutschbein, Stefan Störk, Caroline Morbach

“…Both CS patient groups exhibited a CV risk pattern and metabolic profile worse than healthy subjects but better than individuals with metabolic syndrome. …”
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CAP1: a novel extracellular vesicle marker linked to endothelial senescence in atherosclerosis by Ignacio Hernandez, Laura Botana, Javier Diez-Mata, Laura Tesoro, Beatriz Jimenez-Guirado, Claudia Gonzalez-Cucharero, Nunzio Alcharani, Jose Luis Zamorano, Marta Saura, Carlos Zaragoza

“…Abstract Endothelial senescence (ES) contributes to aging-related disorders and triggers a senescence-associated secretory-pattern (SASP), releasing Extracellular Vesicles (EVs), potentially impacting atherosclerosis. …”
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Unraveling progressive verbal memory deficits in Huntington’s disease: insights from the LASSI-L by Luis A. Sierra, Japleen Kaur, Samuel A. Frank, Samuel A. Frank, Mark A. Halko, Mark A. Halko, Rosie E. Curiel Cid, David A. Loewenstein, Jody Corey-Bloom, Simon Laganiere, Simon Laganiere

“…Furthermore, 88% of participants adhered to the full sequential decline pattern, progressing from deficits in PSI, to frPSI, and then to RSI.DiscussionThe LASSI-L appears to be a useful tool for detecting early and progressive cognitive changes in Huntington’s disease, particularly by capturing the sequential nature of verbal memory deficits, including early vulnerability to interference. …”
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Raet1e Polymorphisms Are Associated with Increased Risk of Developing Premature Coronary Artery Disease and with Some Cardiometabolic Parameters: The GEA Mexican Study by Rosalinda Posadas-Sánchez, Bladimir Roque-Ramírez, José Manuel Rodríguez-Pérez, Nonanzit Pérez-Hernández, José Manuel Fragoso, Teresa Villarreal-Molina, Ramón Coral-Vázquez, Maria Elizabeth Tejero-Barrera, Carlos Posadas-Romero, Gilberto Vargas-Alarcón

“…In healthy controls, associations with a decrease in LDL pattern B, aspartate aminotransaminase, and hypo-α-lipoproteinemia were detected. …”
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Correlation between A3243G and G9053A mtDNA mutations and ATP levels in diabetes mellitus patients using qPCR and electrochemical aptasensors by Iman Permana Maksum, Rahmaniar Mulyani, Yeni Wahyuni Hartati, Irkham, Fanny Rizki Rahmadanthi, Serly Zuliska, Toto Subroto

“…Although no statistically significant differences in ATP levels were observed between groups, descriptive ranges showed lower ATP concentrations in the T2DM + MD group (314 to 919 µM) compared to the T2DM group (746 to 1130 µM), both below the physiological range (1.500 to 1.900 µM). A similar pattern was found for A3243G mutation levels, while G9053A levels overlapped between groups. …”
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Genetic Diversity and Connectivity of Reef-Building <i>Halimeda macroloba</i> in the Indo-Pacific Region by Xiaohan Song, Jianting Yao, Michael Y. Roleda, Yanshuo Liang, Rui Xu, Yude Lin, Shienna Mae C. Gonzaga, Yuqun Du, Delin Duan

“…We suggest that the southwestward ocean currents under the influence of northeast monsoon in the Indo-Pacific region are the main factor in shaping the present genetic structure, and the asexual reproduction of <i>H. macroloba</i> also plays an important role of the low genetic diversity pattern; in addition, the divergence between genetic clusters might be related to the historical isolation led by the paleoclimate oscillation in the Pleistocene. …”
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Tumor-Infiltrating Immune Cells and PD-L1 as Prognostic Biomarkers in Primary Esophageal Small Cell Carcinoma by Xiao Wu, Xiurong Ke, Yangpeng Ni, Liping Kuang, Fan Zhang, Yusheng Lin, Wan Lin, Xiao Xiong, Haihua Huang, Xianjie Lin, Hao Zhang

“…We found that PD-L1 expression was detected in 33.33% (27/81) of all the patients, mostly exhibiting a stroma-only pattern and that it was positively associated with tumor-infiltrating immune cells (CD4+, CD8+, and CD163+). …”
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Malaria vector diversity, transmission and insecticide resistance in Island communities along the Volta lake in Southern Ghana by Abena Ahema Ebuako, Christopher Mfum Owusu-Asenso, Anisa Abdulai, Abdul Rahim Mohammed Sabtiu, Isaac Kwame Sraku, Yaw Akuamoah-Boateng, Cornelia Appiah-Kwarteng, Akua Obeng Forson, Patrick Ferdinand Ayeh-Kumi, Yaw Asare Afrane

“…Blood meal analysis revealed a strong anthropophilic feeding pattern (HBI = 80%). Annual EIRs ranged from 37.40 (ib/m/y) to 100.08 (ib/m/y). …”
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High interleukin-35 expression is associated with the severity of rheumatic mitral stenosis by Ping Wang, Yaxiong Li, Li Zhao, Bin Liu, Zhibin Cai, Peng Zhang, Peng Li, Xuezhen Gao, Yong Zhan

“…Co-localization of p35 and EBI3 was seen in MV tissues of RMS patients in a predominantly perivascular pattern.ConclusionWe show for the first time an increase of IL-35 level in the blood and MV tissues of RMS patients, which is strongly correlated with the severity of RMS. …”
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Reconstructing real-space geometries of polyatomic molecules undergoing strong field laser-induced Coulomb explosion by Aydin Ashrafi-Belgabad, Reza Karimi, Mohammad Monfared, Kaili Tian, Parviz Parvin, Benji Wales, Éric Bisson, Samuel Beaulieu, Mathieu Giguère, Jean-Claude Kieffer, Philippe Lassonde, François Légaré, Heide Ibrahim, Joseph H. Sanderson

“…We reproduce the energy release and the Newton plot momentum patterns of an experiment in which OCS is ionized to the 6+ charge state. …”
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Understanding acoustic indices as multi-taxa biodiversity and habitat quality indicators by Saskia Dröge, Thio Rosin Fulgence, Kristina Osen, Anjaharinony Andry Ny Aina Rakotomalala, Estelle Raveloaritiana, Dominik Schwab, Marie Rolande Soazafy, Annemarie Wurz, Holger Kreft, Dominic Andreas Martin

“…Acoustic monitoring captures the sound of nature, revealing biodiversity patterns and underlying drivers. Acoustic indices are increasingly used to analyse obtained recordings, but studies show inconsistent performance of acoustic indices as biodiversity indicators. …”
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Non-coding RNAs as key regulators in hepatitis B virus-related hepatocellular carcinoma by Prasanna Srinivasan Ramalingam, Liming Zhang, Md Sadique Hussain, Md Sadique Hussain, Gyas Khan, Wedad Mawkili, Ali Hanbashi, Gaurav Gupta, Gaurav Gupta, Purushothaman Balakrishnan, Sivakumar Arumugam

“…Notably, their stability, detectability in bodily fluids, and disease-specific expression patterns render these ncRNAs as highly promising diagnostic and prognostic biomarkers for HBV-HCC. …”
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GUBIC: The global urban biological invasions compendium for plants by Daijiang Li, Luke J. Potgieter, Myla F. J. Aronson, Irena Axmanová, Benjamin Baiser, Marta Carboni, Laura Celesti‐Grapow, Sonja Knapp, Ingolf Kühn, Ana Carolina Lacerda de Matos, Zdeňka Lososová, Flavia A. Montaño‐Centellas, Petr Pyšek, David M. Richardson, Lauren B. Trotta, Rafael D. Zenni, Sarel S. Cilliers, Bruce D. Clarkson, Amy J. S. Davis, Rebecca W. Dolan, Marcin K. Dyderski, Franz Essl, Orou G. Gaoue, Joanne Gui, Charly Géron, Gustavo Heringer, Cang Hui, Anzar A. Khuroo, Stefan Klotz, Peter M. Kotanen, Holger Kreft, Frank A. La Sorte, Jonas J. Lembrechts, Bernd Lenzner, Christopher A. Lepczyk, Scott MacIvor, Cristina Martínez‐Garza, Akira S. Mori, Charles Nilon, Jan Pergl, Stefan J. Siebert, Alyona S. Tretyakova, Toby P. N. Tsang, Kei Uchida, Mark vanKleunen, Montserrat Vilà, Hua‐Feng Wang, Patrick Weigelt, Peter Werner, Nicholas S. G. Williams, Marten Winter, Marc W. Cadotte

“…We hope this dataset will stimulate future research in invasion ecology related to the diversity and distributional patterns of non‐native flora across urban centres worldwide. …”
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Mapping heat-related risks in Swiss cities under different urban tree scenarios by Myke Koopmans, Jonas Schwaab, Ana M. Vicedo-Cabrera, Edouard L. Davin

“…This underscores the positive role of urban trees in mitigating the urban heat effect.The risk mapping approach revealed a distinct spatial pattern for each city and high risk areas were identified.Generally, the high-risk areas in the analyzed cities cover the city centers and areas with high vulnerability.The ‘NoTree’ scenario showed higher risks compared to the baseline situation, illustrating that urban trees currently mitigate heat related risks in Swiss cities. …”
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Gray Matter Differences in Adolescent Psychiatric Inpatients: A Machine Learning Study of Bipolar Disorder and Other Psychopathologies by Renata Rozovsky, Maria Wolfe, Halimah Abdul‐waalee, Mariah Chobany, Greeshma Malgireddy, Jonathan A. Hart, Brianna Lepore, Farzan Vahedifard, Mary L. Phillips, Boris Birmaher, Alex Skeba, Rasim S. Diler, Michele A. Bertocci

“…Conclusions These findings indicate that pattern recognition models focusing on GMVs in regions associated with movement, sensory processing, and cognitive control can effectively distinguish well‐characterized BD‐I/II from other forms of psychopathology, including other specified BD, in a pediatric population. …”
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Novel Differentially Expressed LncRNAs Regulate Artemisinin Biosynthesis in <i>Artemisia annua</i> by Tingyu Ma, Tianyuan Zhang, Jingyuan Song, Xiaofeng Shen, Li Xiang, Yuhua Shi

“…In contrast, <i>BAS</i> (beta-amyrin synthase), which is involved in the artemisinin competing pathway, was strongly down-regulated in HAP compared to LAP, in line with the expression pattern of the linked lncRNA MSTRG.30396.1. By identifying and characterizing lncRNAs that are potentially linked to the regulation of key biosynthetic genes, this work provides new insights into the complex regulatory networks governing artemisinin production in <i>A. annua</i>. …”
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