Impact of PEGylation and hyaluronan functionalization on lipoplex-mediated mRNA delivery to the canine retina by Tatyana Appelbaum, David A. Smith, Kei Takahashi, Jennifer C. Kwok, Hannah Sorenson, William A. Beltran

“…However, a marked reduction in eGFP levels was seen in other retinal layers, displaying a patchy pattern. Similarly, eGFP protein exhibited a patchy distribution across retinal layers outside the RPE. …”
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Subtyping Influenza A Viruses: Genomic Perspectives on Taxonomy by Dr Andrei Deviatkin, Miss Sofya Feoktistova, Mr Egor Degtyarev, Dr Pavel Volchkov

“…Conclusion: The canonical approach to identifying new IAV subtypes relies on serologic tests that detect antibodies against specific viral antigens. …”
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Three Year Prognosis of Patients with Myocardial Infarction Depending on the Body Weight Index: Data of the Kemerovo Acute Coronary Syndrome Registry by D. Yu. Sedykh, A. I. German, O. N. Hryachkova, V. V. Kashtalap, O. L. Barbarash

“…In patients with normal BMI compared with obese patients, fewer deaths from all causes were recorded within 3 years after MI. A similar pattern with respect to the group with normal BMI in terms of high overall mortality was obtained among patients with overweight who had a lower UA. …”
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Parent-of-Origin Effects of the APOB Gene on Adiposity in Young Adults. by Hagit Hochner, Catherine Allard, Einat Granot-Hershkovitz, Jinbo Chen, Colleen M Sitlani, Sandra Sazdovska, Thomas Lumley, Barbara McKnight, Kenneth Rice, Daniel A Enquobahrie, James B Meigs, Pui Kwok, Marie-France Hivert, Ingrid B Borecki, Felicia Gomez, Ting Wang, Cornelia van Duijn, Najaf Amin, Jerome I Rotter, John Stamatoyannopoulos, Vardiella Meiner, Orly Manor, Josée Dupuis, Yechiel Friedlander, David S Siscovick

“…Bioinformatic annotation for rs1367117 revealed a variety of regulatory functions in this region in liver and adipose tissues and a 50% methylation pattern in liver only, consistent with allelic-specific methylation, which may indicate tissue-specific POE. …”
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Application of multi-source remote sensing technologies in identification and evolution mechanism analysis of creep landslides: a case study of Shibatai landslide in Wenchuan earth... by Defu Wang, Li Liu, Li Liu, Chao Luo, Xuehu Wen, Yongxin Li, Dongyu Ren, Wei Tang

“…However, their subtle deformation patterns and complex internal structures present challenges for accurate identification and monitoring using conventional methods. …”
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Sodium glucose co-transporter 2 inhibitors (SGLT2i) for pediatric kidney disease: the future is near by Gilda M. Portalatin, Irene Hong-McAtee, Irene Hong-McAtee, Anna M. Burgner, Edward R. Gould, Tracy E. Hunley, Tracy E. Hunley

“…Regulatory guidance mandated adequately powered studies to detect increased cardiovascular risk from emerging hypoglycemic medications. …”
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Preliminary Investigation of the Spatial-Temporal Characteristics and Vertical Dynamics of Internal Solitary Waves in the South China Sea from SWOT Data by Zhikuan Pan, Zhenhe Zhai, Qi Li, Qianqian Li, Lin Wu, Lifeng Bao

“…This study investigated nonlinear internal solitary waves (ISWs) in the South China Sea using SSHa data from the SWOT satellite mission (Cycles 2 to 20). The distribution patterns and seasonal variations in ISWs were analyzed, revealing that ISWs are more frequently observed in summer while being rarely detected in winter. …”
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Interval Sentinel Lymph Nodes: An Unusual Localization in Patients with Cutaneous Melanoma by A. M. Manganoni, R. Farfaglia, E. Sereni, C. Farisoglio, C. Pizzocaro, D. Marocolo, F. Gavazzoni, L. Pavoni, P. Calzavara-Pinton

“…Knowledge of the unusual drainage patterns will help to ensure the accuracy and the completeness of sentinel nodes identification.…”
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Transcriptome atlases of rat brain regions and their adaptation to diabetes resolution following gastrectomy in the Goto-Kakizaki rat by François Brial, Aurélie Le Lay, Claude Rouch, Edouard Henrion, Mathieu Bourgey, Guillaume Bourque, Mark Lathrop, Christophe Magnan, Dominique Gauguier

“…Abstract Brain regions drive multiple physiological functions through specific gene expression patterns that adapt to environmental influences, drug treatments and disease conditions. …”
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Seeing the unseen in characterizing RNA editome during rice endosperm development by Ming Chen, Lin Xia, Xinyu Tan, Shenghan Gao, Sen Wang, Man Li, Yuansheng Zhang, Tianyi Xu, Yuanyuan Cheng, Yuan Chu, Songnian Hu, Shuangyang Wu, Zhang Zhang

“…Furthermore, we classify mitochondrial genes into three groups, presenting distinct patterns in terms of CDS-recoding events. Besides, we conduct genome-wide screening to detect pentatricopeptide repeat (PPR) proteins and construct PPR-RNA binding profiles, yielding candidate PPR editing factors related to rice endosperm development. …”
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Radiation therapy induced intestinal barrier damage and repair process - differences in salivary metabolites and monitoring of intestinal barrier function by Zhang Jingjing, Wang Kun, Qiao Yanyu, Zhang Mengjie, Chen Yunqing, Tian Yulong, Jiao Xuelong, Tan Xiaojie, Jiang Haitao, Hou Feng

“…This study was conducted to investigate the changes, repair patterns, and potential mechanisms in patients after radiotherapy.MethodsThis study detected inflammatory factors in postoperative intestinal mucosal tissue and serum, as well as metabolites in saliva samples, and collected hematoxylin-eosin (HE)-stained pathological images in CRC patients who had received and did not receive radiotherapy.ResultsThe results showed that after radiotherapy, there were significantly impaired intestinal mucosal tissue structure; obviously elevated inflammatory factors in intestinal mucosal tissue and blood; as well as upregulation/downregulation of metabolites in saliva samples.ConclusionIn conclusion, findings in this study may provide potential reference for predicting the recovery of intestinal mucosa and selecting the optimal timing for surgery after radiotherapy. …”
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Time Evolution of Bacterial Resistance Observed with Principal Component Analysis by Claudia P. Barrera Patiño, Mitchell Bonner, Andrew Ramos Borsatto, Jennifer M. Soares, Kate C. Blanco, Vanderlei S. Bagnato

“…<b>Results</b>: The processing and data analysis with machine learning algorithms performed on this FTIR spectral database allowed for the identification of patterns across minimum inhibitory concentration (MIC) values associated with different exposure times and both clusters from hierarchical classification and PCA. …”
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Artificial Intelligence in Chest Radiography—A Comparative Review of Human and Veterinary Medicine by Andrea Rubini, Roberto Di Via, Vito Paolo Pastore, Francesca Del Signore, Martina Rosto, Andrea De Bonis, Francesca Odone, Massimo Vignoli

“…Deep learning-based models assist radiologists by detecting patterns, generating probability maps, and predicting outcomes like heart failure. …”
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Near-Surface Geochemical Anomalies Integrated with Seismic and Well Data over the Contact of the Outer Carpathians and the Carpathian Foredeep (SE Poland) by Henryk Sechman, Adrianna Góra, Anna Twaróg, Piotr Guzy, Ewelina Górska-Mruk, Wojciech Górecki

“…The location and range of 13 anomalous zones are controlled by the patterns of both the Dębno and the Wojnicz slice-folds. …”
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Multivariate stochastic modeling for transcriptional dynamics with cell-specific latent time using SDEvelo by Xu Liao, Lican Kang, Yihao Peng, Xiaoran Chai, Peng Xie, Chengqi Lin, Hongkai Ji, Yuling Jiao, Jin Liu

“…Using both simulated and four scRNA-seq and spatial transcriptomics datasets, we show that SDEvelo can model the random dynamic patterns of mature-state cells while accurately detecting carcinogenesis. …”
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A riverbank erosion early warning system (EWS-RE) for braided river: a case of the Brahmaputra–Jamuna by Shampa, Hussain Muhammad Muktadir, Israt Jahan Nejhum, Md. Majurul Hussain, Anup Bhowmik, Nazmul Islam Ananto, Fardin Anam Aungon, Showvik Biswas, Mohammad Muddassir Islam

“…Model outputs and predicted erosion patterns were validated against actual riverbank changes observed in the year 2019. …”
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DNA barcoding highlights taxonomic uncertainties and cryptic lineages of São Francisco River basin fishes by Denis Bruno Santos Marques Nunes, Alany Itala Pontes, Leandro Ferreira dos Santos, Leonardo Luís Calado, Luciano Freitas Barros-Neto, Silvia Yasmin Lustosa-Costa, Sergio Maia Queiroz Lima, Uedson Pereira Jacobina

“…Analyses revealed distinct patterns of genetic divergence. The BOLD platform identified 111 bins, 75 as MATCH, 32 as SPLIT, two as MERGE and two MIXTURE. …”
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Metabolism-Related Genes SMOX and SUCLG2 as Immunological and Prognostic Biomarkers in Colorectal Cancer: A Pan-Cancer Analysis by Zuming Xiong, Yirong Lin, Yongjun Yang, Wenxin Li, Wei Huang, Sen Zhang

“…Expression patterns and underlying mechanisms of metabolism-related genes SMOX and SUCLG2 in pan-cancer remain unclear. …”
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Characterizing Surface Deformation of the Earthquake-Induced Daguangbao Landslide by Combining Satellite- and Ground-Based InSAR by Xiaomeng Wang, Wenjun Zhang, Jialun Cai, Xiaowen Wang, Zhouhang Wu, Jing Fan, Yitong Yao, Binlin Deng

“…The post-earthquake evolution of the DGBL has garnered significant attention in recent years; however, its deformation patterns remain poorly characterized owing to the complex local topography. …”
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Two decades of mass-balance observations on Aldegondabreen, Spitsbergen: interannual variability and sensitivity to climate change by Anton Terekhov, Uliana Prokhorova, Sergey Verkulich, Vasiliy Demidov, Olga Sidorova, Mikhail Anisimov, Kseniia Romashova

“…Therefore, the decadal periodicity of the Aldegondabreen mass balance follows general archipelago patterns that are determined by regional-scale factors. …”
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