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6741
The Prevalence and Characteristics of IgA Antibodies to β2-Spectrin and CBX3 in Immunoglobulin A Nephropathy
Published 2025-05-01“…The study also assessed the surface expression of the autoantigens on human mesangial cells and the pattern of O-glycosylation of serum anti-SPTBN1 and anti-CBX3 IgA antibodies. …”
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6742
Diversity of questing ticks and prevalence of tick-associated pathogens in Khao Kheow-Khao Chomphu Wildlife Sanctuary, Chon Buri, Thailand
Published 2024-01-01“…Phylogenetic analysis grouped the newly generated sequences in the clades of Anaplasma bovis, Babesia gibsoni, Theileria cervi, Bartonella henselae, and Rickettsia montanensis. A seasonal pattern of pathogen appearance was detected during November to February, the cool season in Thailand. …”
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6743
Introduction of a Divergent Canine Parvovirus Type 2b Strain with a Dog in Sicily, Southern Italy, Through the Mediterranean Sea Route to Europe
Published 2025-01-01“…It is at least suggestive that the inferred spreading pattern overlaps with the routes often followed by migrants travelling from Asia and Middle East to Europe, passing through Africa. …”
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6744
Proteomic Diversity of the Sea Anemone <i>Actinia fragacea</i>: Comparative Analysis of Nematocyst Venom, Mucus, and Tissue-Specific Profiles
Published 2025-02-01“…Several other bioactive compounds with distinctive defense functions were also detected, including enzymes, pattern recognition proteins (PRPs), and neuropeptides. …”
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6745
Technical and Analytical Approach for Breast Reconstruction With IMAP Propeller Flap
Published 2024-12-01“…In the selected patients, a Wise skin-pattern reduction was designed to allow elevation of a transversely oriented flap including both inferior poles. …”
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6746
Metabolomic Signatures Highlight Fiber-Degrading Bacteroides Species in Mediterranean Diet Response Among Ulcerative Colitis
Published 2025-01-01“…Background and Aims: The Mediterranean diet pattern (MDP) is associated with health-associated gut microbes and metabolites. …”
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6747
Mapping autoantibody targets of full-length C-reactive protein in systemic lupus erythematosus: importance for neutrophil function and classical complement activation
Published 2025-05-01“…C-reactive protein (CRP) is an important pattern recognition molecule of innate immunity. Autoantibodies targeting CRP are common in patients with systemic lupus erythematosus (SLE) and the levels correlate with disease activity. …”
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6748
Hsa-miR-21-5p is induced by interleukin-6 and affects multiple pathogenic factors associated with fibroblast-like synoviocytes in rheumatoid arthritis
Published 2025-06-01“…Next-generation sequencing (small RNA-seq) was performed on primary cultured FLS derived from patients with RA to analyze the mature miRNA expression pattern. To assess inflammation-induced changes in miRNA levels, FLS were cultured with cytokines and evaluated by RT-qPCR. …”
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6749
Correlation between digestive system development and feedback regulation of cholecystokinin and trypsin in Megalobrama pellegrini larvae and juveniles
Published 2025-07-01“…A negative feedback regulation was identified between CCK content and trypsin activity; however, the secretion pattern was oscillated by the development of the digestive system structure. …”
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6750
Fluorescein-distribution in confocal laser endomicroscopy allows for discrimination between primary brain tumours and metastases
Published 2025-04-01“…The staining characteristics of SF yet remain unclear.MethodsIn order to understand the dyeing behaviour of SF, we initiated a pilot study, comparing the staining pattern when incubating established tumour cell lines with SF in vitro to the distribution of intravenously applied SF in situ—examined with CLE ex vivo as well in vivo.ResultsIn vitro, the cell lines showed a hyperbolic, time-dependent cellular accumulation of SF. …”
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6751
Cardiac muscle organization revealed in 3-D by imaging whole-mount mouse hearts using two-photon fluorescence and confocal microscopy
Published 2015-11-01“…Using 2-D and 3-D morphometric analysis, we found that the t/t heart had anomalous ventricular shape, volume, and wall thickness, as well as a disrupted sarcomere pattern. We further validated our approach using decellularized hearts that had been cultured with 3T3 fibroblasts, which were tracked using a nuclear label. …”
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6752
A complex spatial inventory of land degradation and desertification in Romania
Published 2025-07-01“…By using multiple geospatial datasets, analyzed individually and combined into a Land Multi-degradation Index, a complex spatial pattern of land degradation and desertification was revealed across the country. …”
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6753
Adenosine Receptor 3 in Liver Cancer: Expression Variability, Epigenetic Modulation, and Enhanced Histone Deacetylase Inhibitor Effects
Published 2025-01-01“…However, further data are required to clarify ADORA3 expression patterns in liver cancer, mechanisms of action, and the potential for combination therapies to inform patient selection for future clinical trials. …”
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6754
Predicting lymph node metastasis of clinical T1 non-small cell lung cancer: a brief review of possible methodologies and controversies
Published 2024-12-01“…However, the preoperative lymph node staging and intraoperative lymph node dissection patterns of operable clinical T1 NSCLC are still subject to much disagreement, as well as the heterogeneity between primary tumors and metastatic lymph nodes poses a challenge in designing effective treatment strategies. …”
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6755
Spatiotemporal Changes of Reference Evapotranspiration in Mongolia during 1980–2006
Published 2016-01-01“…The changing trends and magnitude of RET were detected by the Mann-Kendall test and Theil-Sen’s slope methods. …”
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6756
Role of inflammasomes in cancer immunity: mechanisms and therapeutic potential
Published 2025-03-01“…Abstract Inflammasomes are multi-protein complexes that detect pathogenic and damage-associated molecular patterns, activating caspase-1, pyroptosis, and the maturation of pro-inflammatory cytokines such as IL-1β and IL-18Within the tumor microenvironment, inflammasomes like NLRP3 play critical roles in cancer initiation, promotion, and progression. …”
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6757
An eight-year study of Shigella species in Beijing, China: serodiversity, virulence genes, and antimicrobial resistance
Published 2014-07-01“…Introduction: This study was conducted to determine the prevalence of serotypes, virulence factors, and antimicrobial resistance patterns of Shigella spp. in Beijing, China, from 2004 to 2011. …”
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6758
Spatially Resolved River Monitoring by UAV-Borne 4D-Imaging Radar: Experiments and Preliminary Validation
Published 2025-01-01“…The final output, a georeferenced composite image derived from multiple UAV acquired radar images, provides detailed insights into complex, nonlaminar water flow patterns.…”
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6759
Characterization of Salmonella Enteritidis isolated from foods and patients in northern Morocco
Published 2009-10-01“…Enteritidis was genotyped and showed four different patterns by PFGE and six by ERIC-PCR. Accordingly, high genetic similarity and limited genetic diversity were found for these strains from north of Morocco. …”
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6760
Metabolic syndrome and pancreatic lesions
Published 2013-05-01“…Direct CT signs of SP include decrease in pancreatic density score (<30 HU), lobulated pattern of the gland with pronounced fatty layers. …”
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