Features of neuroglia at the epicenter of spinal cord contusion injury and at distant areas in mini-pigs by R. R. Garifulin, A. A. Izmailov, V. A. Markosyan, I. S. Minyazeva, V. V. Valiullin, R. R. Islamov

“…The results of the study revealed a similar pattern of macro- and microglial cell distribution both in the  SCI region and in remote areas. …”
Get full text

Structural and functional correlations in the pre-perimetric and the initial stages of glaucomatous optic neuropathy by M. O. Kirillova, A. N. Zhuravleva, M. V. Zueva, I. V. Tsapenko

“…Results.In patients with suspected glaucoma, changes in the parameters of transient pattern-ERG correlated with RNFL thinning in the macular region, inner plexiform layer (IPL), and ganglion cell layer(GCL) in the parafoveal area. …”
Get full text

Single-cell spatial transcriptomics unravels cell states and ecosystems associated with clinical response to immunotherapy by Sjoerd H van der Burg, Ziena Abdulrahman, Mariette I E van Poelgeest, Roderick C Slieker, Marij J P Welters, Daniel McGuire

“…Findings were validated against public single-cell transcriptomic data sets to assess their broader relevance across tumor types.Results Profound heterogeneity within the TME was detected across the response groups. CR lesions exhibited a higher ratio of immune-supportive to immune-suppressive cells—a pattern mirrored in other solid tumors following neoadjuvant checkpoint blockade. …”
Get full text

Soft-tissue modification in Class III non-growing patients treated with clear aligners: a prospective clinical trial by R. Lione, C. Pavoni, F. Gazzani, F. C. De Razza, F. C. De Razza, L. Lugli, P. Cozza

“…A mild better projection of the upper lip was detected at the end of treatment, mainly due to the extensive use of Class III elastics.…”
Get full text

Post-Marketing Pharmacovigilance of Canakinumab from the FDA Adverse Event Reporting System (FAERS) by Weidong Zhang, Yunzhou Chen, Zeyu Yao, Mengling Ouyang, Minghui Sun, Shupeng Zou

“…All positive signals followed an early failure pattern, with the incidence of canakinumab-associated AEs decreasing over time. …”
Get full text

Capture—Incubate—Release: An Animal‐Friendly Approach to Assess Local Aquatic Macroinvertebrate Species Diversity Through Environmental DNA Metabarcoding by Mandy Sander, Arne J. Beermann, Dominik Buchner, Martina Weiss, Marie‐Thérése Werner, Florian Leese

“…However, the experiment showed a species‐specific eDNA release pattern that was not directly linked to body sclerotization nor biomass. …”
Get full text

Distinct neural representations of different linguistic components following sign language learning by Yael Coldham, Neta Haluts, Eden Elbaz, Tamar Ben-David, Nell Racabi, Shachar Gal, Michal Bernstein-Eliav, Naama Friedmann, Ido Tavor

“…Activation patterns while processing different linguistic components post-learning were spatially distinct, suggesting a unique neural representation for each component. …”
Get full text

Assessment of cigarette butt pollution and its Spatial distribution in Northeastern Iran by Narges Babaei, Fateme Kabirinia, Ali Asghar Nahafpoor, Ziaeddin Bonyadi

“…Severe pollution (CBPI > 10) was detected in 33.33% of the studied areas. The results revealed that factors such as population density, land use patterns, ground surface quality, annual rainfall, and groundwater proximity significantly influenced CB distribution. …”
Get full text

Associations between the genotypes of the calpain and cal-pastatin genes and performance, carcass parameters and meat quality in Nelore cattle by Claudiana Esteves Couto, Kalynka Gabriella do Livramento, Luciano Vilela Paiva, Ana Paula Peconick, César Augusto Pospissil Garbossa, Melissa Siqueira Martins, Peter Bitencourt Faria

“…For molecular analysis, genomic DNA was extracted from the muscle tissue of the animals, and the polymerase chain reaction–single-strand conformation polymorphism (PCR–SSCP) technique was used to detect and identify the following polymorphisms: three genotypes of the CAPN9 gene (exon 9), eight patterns in the CAPN14 gene (exon 14) and four genotypes of the CAST5 gene (exon 5). …”
Get full text

Interplay between oxidative stress, neuroinflammatory cytokines and melatonin in Alzheimer's disease: Insights from cerebrospinal fluid analysis by Francisco Artime-Naveda, David Hevia, Rebeca Alonso-Arias, Carmen Martínez, Isabel Quirós-González, Rafael Cernuda-Cernuda, Alejando Alvarez-Artime, Iván Menéndez-Valle, Rosa M. Sainz, Juan C. Mayo

“…On the contrary, AFMK showed the opposite pattern, with higher levels in samples from patients displaying high T-tau and P-tau levels. …”
Get full text

Uncovering Surgical Dynamics and Trends in Early Breast Cancer Stage at Diagnosis: Key Insights From a Two-Decade Argentine Database Analysis by Pablo Mandó, Verónica Fabiano, Soledad Gomez Guasch, Giuliana Colucci, Rodrigo Sánchez-Bayona, Federico Coló, Martín Loza, Francisco Von Stecher, Mora Amat, Máximo de la Vega, Maria Victoria Costanzo, Adrian Nervo, Jorge Nadal, Reinaldo Chacón, Florencia Perazzo

“…The Argentine Society of Mastology has maintained a comprehensive Breast Cancer Registry that provides valuable data for analyzing these trends.MATERIALS AND METHODSThis retrospective analysis of the Breast Cancer Registry database evaluated changes in stages at the time of surgery, patterns of surgical care, and factors associated with higher stage diagnoses in patients with breast cancer in Argentina from January 2000 to December 2019.RESULTSOverall, 13,239 patients met the inclusion criteria. …”
Get full text

The role of fMRI in the mind decoding process in adults: a systematic review by Sahal Alotaibi, Maher Mohammed Alotaibi, Faisal Saleh Alghamdi, Mishaal Abdullah Alshehri, Khaled Majed Bamusa, Ziyad Faiz Almalki, Sultan Alamri, Ahmad Joman Alghamdi, Mohammed Alhazmi, Hamid Osman, Mayeen U. Khandaker

“…Studies were selected based on strict inclusion and exclusion criteria: peer-reviewed; published between 2000 and 2024 (in English); focused on adults; investigated mind-reading (mental state decoding, brain-computer interfaces) or related processes; and employed various mind-reading techniques (pattern classification, multivariate analysis, decoding algorithms). …”
Get full text

Small RNA deep sequencing reveals full-length genome of Citrus yellow vein clearing virus in Chongqing, China by Yun-qi YU, Qiong WU, Hua-nan SU, Xue-feng WANG, Meng-ji CAO, Chang-yong ZHOU

“…Mapping analysis of viral-derived siRNA (vsiRNA) profiles revealed an uneven distribution pattern of their generations along both positive and negative genome strands, and 22- and 21-nt vsiRNAs ranked the majority. …”
Get full text

An optimization method for hemi-diaphragm measurement of dynamic chest X-ray radiography during respiration based on graphics and diaphragm motion consistency criterion by Yingjian Yang, Jie Zheng, Peng Guo, Tianqi Wu, Qi Gao, Yong Li, Chengcheng Liu, Yang Liu, Yingwei Guo, Huai Chen

“…Lastly, these abnormal hemi-diaphragms are optimized based on the consistency criterion of diaphragm motion.ResultsResults show that the proposed optimization method can effectively measure the hemi-diaphragm, even in the presence of the inapparent cardiophrenic angle caused by abnormal deformations of the lung field morphology during respiration, reducing the mean error by 49.050 pixels (49.050 × 417 μm = 20,453.85 μm).DiscussionTherefore, the proposed optimization method may become an effective tool for precision healthcare to find the pattern of diaphragm movement during respiratory interventions.…”
Get full text

Cytokines in cerebrospinal fluid in the case of meningitis in children by L. A. Alekseyeva, E. M. Mazayeva, N. V. Skripchenko, N. E. Monakhova, T. V. Bessonova

“…The decrease of cytokine level was detected in the period of reconvalescence.Conclusion: the cytokine concentration increase in the cerebrospinal fluid in the acute stage of bacterial purulent and serous meningitis indicates both the presence of common patterns of neuroinfectious process and the features caused by the agent, and their increase in the stage of reconvalescense demonstrates the remaining intrathecal inflammation.…”
Get full text

Biflavonoid Profiling of <i>Juniperus</i> Species: The Influence of Plant Part and Growing Location by Barbara Medvedec, Iva Jurčević Šangut, Armin Macanović, Erna Karalija, Dunja Šamec

“…Biflavonoids are an important group of flavonoids found in <i>Juniperus</i> species, yet their distribution and accumulation patterns remain insufficiently explored. In this study, we applied a method for the simultaneous quantification of seven biflavonoids to analyze different plant parts of <i>J. communis</i>, <i>J. communis</i> subsp. …”
Get full text

Study on the distribution characteristics of α-Solanine in different parts of Solanum nigrum based on infrared spectroscopy by Yan Liu, Jiankang Zhao, Minzhen Si

“…This study employs Fourier Transform Infrared Spectroscopy (FTIR) to quantitatively analyze the distribution patterns and metabolic roles of α-solanine across different organs (roots, stems, leaves, flowers, and fruits) of Solanum nigrum. …”
Get full text

Simultaneous Instance and Attribute Selection for Noise Filtering by Yenny Villuendas-Rey, Claudia C. Tusell-Rey, Oscar Camacho-Nieto

“…Removing or reducing noise can help classification algorithms focus on relevant patterns, preventing them from being affected by irrelevant or incorrect information. …”
Get full text

Health Care Seeking Behavior of Persons with Acute Chagas Disease in Rural Argentina: A Qualitative View by Ignacio Llovet, Graciela Dinardi, Cecilia Canevari, Nahal Torabi

“…Narratives of 25 in-depth interviews carried out in 2005 and 2006 are analyzed identifying patterns of health care seeking behavior followed by acute cases. …”
Get full text

GENETIC DIVERSITY OF DRUG RESISTANT STRAINS OF MYCOBACTERIUM TUBERCULOSIS IN OMSK REGION by O. A. Pаsechnik, M. A. Dymovа, V. L. Stаsenko, M. P. Tаtаrintsevа, I. P. Kolesnikovа, E. S. Lyapinа

“…Drug resistance was detected in 48.0% of new cases. Among drug resistance patterns, MDR made 57%, and extensive drug resistance (XDR) increased from 2.5 to 7.0%. …”
Get full text