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6441
An In Vitro RNA Editing-Based Reporter Assay for Transcriptional Activity of Therapeutic Gene in Gene Therapy Products
Published 2024-11-01“…Of note, all sensors that targeted different regions, including the gene of interest, tag sequence, and 3′ untranslated region, showed a dose-dependent response pattern. The sensor reporter assay, which was used for quantifying the transcriptional activity of recombinant adeno-associated virus-based gene therapy products, revealed excellent performance in terms of assay specificity, precision (inter-assay relative standard deviation < 15%), accuracy (90–115% recovery), and linearity (R<sup>2</sup> > 0.99). …”
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6442
The adeH and adeS Efflux Pump Genes in Imipenem and Colistin-Resistant Acinetobacter baumannii Clinical Isolates
Published 2022-12-01“…The antibiotic susceptibility pattern was examined using the broth microdilution MIC method according to Clinical and Laboratory Standards Institute (CLSI) guidelines. …”
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6443
Dingo movement depends on sex, social status and litter size
Published 2025-07-01“…In common with other carnivores, these results suggest that ranging patterns depend on the sex and breeding status of the individual and potentially on levels of competition. …”
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6444
β-1,3-Glucan Recognition Protein Can Inhibit the Proliferation of <i>Bombyx mori</i> Cytoplasmic Polyhedrosis Virus
Published 2025-04-01“…Insects detect pathogens through their germ-line encoded pattern recognition receptors (PRRs). …”
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6445
Determination of Levels of Organochlorine, Organophosphorus, and Pyrethroid Pesticide Residues in Vegetables from Markets in Dar es Salaam by GC-MS
Published 2017-01-01“…The most frequently detected compounds were p,p′-DDD and chlorpyrifos. …”
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6446
Pathogenic Menace of MDR Bacteria in Stool and Throat Swab Surveillance Cultures of Hematopoietic Stem Cell Recipients and Evaluation of Post-Transplant Bloodstream Infections: A C...
Published 2025-01-01“…We have conducted this study to determine the profile of organisms isolated from stool and throat swab cultures, their susceptibility pattern, and the presence of MDRO to detect post-transplant bloodstream infections in this tertiary care teaching hospital in Kolkata. …”
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6447
Spatial and Temporal Variation in the Occurrence and Abundance of the Freshwater Turtles in Water Bodies of a Peri-Urban Area in the Midwestern Brazil
Published 2025-08-01“…Despite the syntopic occurrence of Phrynops geoffroanus and Mesoclemmys vanderhaegei, the occurrence of the former influenced the occurrence and abundance of the latter species, thus presenting different patterns over time and space. …”
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6448
Skating efficiency and technique during roller speed skate using innovative piezoelectric smart socks: an exploratory study
Published 2025-07-01“…Comparative analysis of a high level competitive and a novice skater highlighted the ability of the system to detect different motor patterns while skating. The high level competitive exhibited different types of strides, with different utilization of foot areas and subsequent accelerometric values. …”
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6449
AI-driven fusion of multimodal data for Alzheimer’s disease biomarker assessment
Published 2025-08-01“…Abstract Alzheimer’s disease (AD) diagnosis hinges on detecting amyloid beta (Aβ) plaques and neurofibrillary tau (τ) tangles, typically assessed using PET imaging. …”
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6450
Positioning and Mitigating Mining-Induced Phase Gradients for InSAR Phase Unwrapping
Published 2025-01-01“…Second, we model the nonlinear phase gradients by means of generalized Gaussian distribution, followed by minimizing the angular deviation between observed and modelled phase patterns in each detected interferometric patch. After defringing mining-induced phase gradients, we evaluate the impact of nonlinear high phase gradients on phase unwrapping, using synthetic data and Sentinel-1 dataset over Datong mining area, Shanxi Province. …”
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6451
Electron Paramagnetic Resonance in Lignocellulosic Biomass Pyrolysis Mechanism: Advancements, Applications, and Prospects
Published 2025-03-01“…By providing a comprehensive review of radical evolutionary patterns during biomass pyrolysis using EPR, we conclude with limitations and prospects, which may offer a new perspective on the mechanism of biomass pyrolysis and the optimization of pyrolysis conditions.…”
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6452
Systems Biology of Recombinant 2G12 and 353/11 mAb Production in CHO-K1 Cell Lines at Phosphoproteome Level
Published 2025-02-01“…Furthermore, a substantial number of changes in the phosphorylation pattern related to tunicamycin treatment have been detected. …”
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6453
A comprehensive machine learning for high throughput Tuberculosis sequence analysis, functional annotation, and visualization
Published 2025-07-01“…Imaging scans leverage pattern recognition to predict outcomes, diagnose disorders, and suggest treatments. …”
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6454
Uptake, accumulation and gene response of Sb(Ⅴ) in Arabidopsis thaliana
Published 2024-12-01“…This study revealed the pattern of Sb(V) uptake by plants and elucidated the mechanism of Sb(V) uptake by plants from the perspectives of kinetics, physiology, and genetics.…”
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6455
Retinoic and ascorbic acids induce osteoblast differentiation from human dental pulp mesenchymal stem cells
Published 2021-04-01“…Morphologically, the cells treated with RA and RA + AA were larger and more elongated than the control cells. A mesh pattern was observed in cells treated with AA. Numerous calcified nodules were present in cells treated with RA, AA, and RA + AA. …”
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6456
Using optimization tools to explore stratospheric aerosol injection strategies
Published 2025-08-01“…Nonetheless, these strategies still do not fully compensate for the pattern of climate changes caused by increased greenhouse gas concentrations, creating a novel climate state. …”
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6457
2023 activity of Nyamulagira volcano monitored by SAR interferometric coherence
Published 2025-12-01“…In addition, the time needed for the lava to solidify is tentatively estimated by studying the statistical behavior of the coherence pattern ascribable to a lava flow. Experimental results show a significant lava effusion inside Nyamulagira caldera from the beginning of March, while in mid-May the increase of the activity induced an overflowing from the caldera, with a lava flow observed along the NW flank of the volcano. …”
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6458
Mapping seasonal soil deformation in expansive clay using synthetic aperture radar interferometry: A case study in Diamniadio, Senegal
Published 2025-09-01“…Results reveal a clear pattern of seasonal uplift during the wet season (July–October) and subsidence during the dry season (October–June), with vertical deformation amplitudes ranging from 0.5 to 5 mm. …”
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6459
Pathological Changes and Sodium Rhodizonate Test as Tools for Investigating Gunshot Wounds in Veterinary Forensic Pathology
Published 2024-10-01“…However, the number of positive cases and the pattern of lead distribution varied with the shooting range. …”
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6460
A lightweight transformer based multi task learning model with dynamic weight allocation for improved vulnerability prediction
Published 2025-08-01“…Traditional methods, such as single-task learning and ensemble approaches, often struggle with these challenges, particularly in detecting rare but critical vulnerabilities. To address this, we propose the MTLPT: Multi-Task Learning with Position Encoding and Lightweight Transformer for Vulnerability Prediction, a novel multi-task learning framework that leverages custom lightweight Transformer blocks and position encoding layers to effectively capture long-range dependencies and complex patterns in source code. …”
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