Palmitoleic acid sensitizes vancomycin-resistant Staphylococcus aureus to vancomycin by outpacing the expression of resistance genes by Zajeba Tabashsum, Michelle Angeles-Solano, Ashelyn E. Sidders, Joshua B. Parsons, Sarah E. Rowe

“…We previously showed that palmitoleic acid, a host-produced monounsaturated fatty acid, combined with vancomycin led to an accumulation of large fluid patches in the bacterial membrane, resulting in membrane destabilization and cell death. …”
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An unmanned surface vehicle for acoustic telemetry surveys of coastal fishes: range testing, real world performance, and comparison with a stationary tracking array by Eric Reyier, Joseph Iafrate, Bonnie Ahr, Stephanie Watwood, Douglas Scheidt, Jacob Levenson, Chris Schumann

“…While single gliders cannot replace stationary arrays in most situations, they are realistic solutions for relocating animals in remote locations, monitoring dispersal across discrete habitat patches (e.g., reefs, wind turbines), and providing highly localized habitat context.…”
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A Multiband Dual Linear-to-Circular Polarization Conversion Reflective Metasurface Design Based on Liquid Crystal for X-Band Applications by Xinju Wang, Lihan Tong, Peng Chen, Lu Liu, Yutong Yin, Haowei Zhang

“…The polarization conversion (PC) structure employs an orthogonal anisotropic design, utilizing logarithmic functions to create two pairs of bowtie microstrip patches for linear-to-circular polarization conversion (LCPC). …”
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Potentially Inappropriate Use of Transdermal Fentanyl in Working-Age and Older Adult Populations with Non-Cancer Pain: Nationwide Cross-Sectional Study by Seunghyun Cheon, Seo-Yong Choi, Kyu Ri Kim, Han-Gon Choi, Jee-Eun Chung

“… Abstract BackgroundAs a potent opioid analgesic, fentanyl transdermal patches (FTDs) have been widely used in patients with moderate to severe pain. …”
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Decreased GZMB, NRP1, ITPR1, and SERPINB9 Transcripts Lead to Reduced Regulatory T Cells Suppressive Capacity in Generalized Vitiligo Patients by Prashant S. Giri, Ankit H. Bharti, Mitesh Dwivedi

“…Generalized vitiligo (GV) is an autoimmune skin disease characterized by bilateral white patches over the entire body. Regulatory T cells (Tregs) maintain peripheral tolerance; however, they are found to be reduced in numbers and function in vitiligo patients. …”
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CONTEXTUAL APPROACH TO LITERARY CRITICISM: DOSTOEVSKY AND PSYCHOANALYSIS by V. G. Kalashnikov

“…Accordingly, in this paper on the basis of later research context is understood as a psychological mechanism of semantic, objectified in external forms of test patches, social and communicative situations, etc. …”
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Riparian habitat quality and seasonality drives spatiotemporal habitat ecology of sympatric Asian otters in southern Western Ghats by Ankit Moun, Tharmalingam Ramesh, Tharmalingam Ramesh, Riddhika Kalle, Riddhika Kalle

“…The long-term persistence of sympatric Asian otters in the Bhavani-Noyyal river basin would depend on the availability of high-quality riparian habitat patches. Our findings emphasize the need to develop comprehensive riparian habitat management plans in the southern Western Ghats which involves restoration of fragmented riparian zones and maintenance of riparian habitat heterogeneity to facilitate freshwater connectivity and movements of sympatric otters.…”
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In vivo antiviral efficacy of LCTG-002, a pooled, purified human milk secretory IgA product, against SARS-CoV-2 in a murine model of COVID-19 by Viraj Mane, Rikin Mehta, Nadine Alvarez, Vijeta Sharma, Steven Park, Alisa Fox, Claire DeCarlo, Xiaoqi Yang, David S. Perlin, Rebecca L. R. Powell

“…Western blot demonstrated that all batches consisted predominantly of sIgA. Compared to control IgA, LCTG-002 demonstrated significantly higher Spike binding (mean endpoint of 0.87 versus 5.87). …”
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Biphasic effects of Callicarpa nudiflora water extract on rumen fermentation in vitro and microbial communities in sheep by Wanqin Yang, Wanqin Yang, Runhang Li, Wenxi Wang, Kunna Li, Yiying Huang, Ying Ying, Yuning Liu, Hongxin Wu

“…Each treatment was replicated in duplicate across three independent batches, resulting in a total of six biological replicates per treatment. …”
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Study of the immunological efficacy and safety of a candidate vaccine against Lassa hemorrhagic fever by O. Popova, O. V. Zubkova, T. A. Ozharovskaia, D. I. Zrelkin, D. V. Voronina, P. P. Goldovskaya, V. Yu. Kan, I. V. Dolzhikova, A. V. Kovyrshina, D. M. Grousova, I. A. Ermolova, D. V. Shcheblyakov, D. Yu. Logunov, A. L. Gintsburg

“…Both recombinant vectors contain the codon-optimized sequence of Lassa virus glycoprotein. Two experimental batches of the candidate vaccine were produced under GMP-conditions and analyzed. …”
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Landscape as a Shared Space for Badgers and Cattle: Insights Into Indirect Contact and Bovine Tuberculosis Transmission Risk by Emma L. Holmes, Maria J. H. O’Hagan, Fraser D. Menzies, Andrew W. Byrne, Kathryn R. McBride, Charles M. McCormick, David M. Scantlebury, Neil Reid

“…Delaying grazing of fodder fields after (silage) harvest until sward length has increased, restricting grazing to improved pastures, keeping calves with cows longer, or ensuring all batches of cattle have at least some calves present and not grazing fields with badger setts (or fencing around setts to prevent cattle access) may provide simple, cost‐effective strategies to reduce indirect badger–cattle contact, thus potentially lowering bTB transmission risk.…”
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Development and validation of the immune signature to predict distant metastasis in patients with nasopharyngeal carcinoma by Ze-Xian Liu, Rui Sun, Jian-Ming Li, Sai-Lan Liu, Li-Juan Bian, Qiu-Yan Chen, Xue-Song Sun, Dong-Hua Luo, Xiao-Yun Li, Bei-Bei Xiao, Jin-Jie Yan, Zi-Jian Lu, Shu-Mei Yan, Li Yuan, Lin-Quan Tang, Hai-Qiang Mai

“…The immune signature consisting of four immune markers (PD-L1+ CD163+, CXCR5, CD117) in intratumor was adopted to classify patients into high and low risk in the training cohort and it showed a high level of reproducibility between different batches of samples (r=0.988 for intratumor; p<0.0001). …”
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Improvements in the land surface configuration to better simulate seasonal snow cover in the European Alps with the CNRM-AROME (cycle 46) convection-permitting regional climate mod... by D. Monteiro, C. Caillaud, M. Lafaysse, A. Napoly, M. Fructus, A. Alias, S. Morin

“…More specifically, the study tests the influence of various changes in the land surface configuration, such as the use of multi-layer soil and snow schemes, the division of the energy balance calculation by surface type within a grid cell (multiple patches), and new physiographic databases and parameter adjustments. …”
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Dissecting the Impact of Genetic Background on Oncogenic Response to Radiation Exposure in the <i>Ptch1</i>^+/− Mouse Model by Barbara Tanno, Emiliano Fratini, Simona Leonardi, Flavia Novelli, Valentina Pisano, Mariateresa Mancuso, Simonetta Pazzaglia

“…The sonic hedgehog (SHH) pathway is indispensable for the normal development of the cerebellum, and MB is often caused by persistent SHH activation owing to mutations in pathway components. Patched1 (<i>PTCH1</i>) is the primary receptor for the SHH ligand and a negative regulator of the SHH signal transduction pathway. …”
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Machine learning analysis of pathological images to predict 1-year progression-free survival of immunotherapy in patients with small-cell lung cancer by Hirotaka Matsumoto, Hiroaki Akamatsu, Nobuyuki Yamamoto, Yuki Sato, Daichi Fujimoto, Yoshihiko Taniguchi, Motohiro Tamiya, Yasuhiro Koh, Junya Fukuoka, Hisashi Tanaka, Naoki Furuya, Ryota Shibaki, Tsukasa Nozawa, Akira Sano, Yuka Kitamura, Takashi Kijima, Toshihide Yokoyama, Satoru Miura, Akito Hata, Jun Sugisaka

“…The primary outcome was the mean area under the curve (AUC) of machine learning models in predicting the 1-year PFS.Results We analyzed 100,544 patches of pathological images from 78 patients. The mean AUC values of patient information, pathological image, and combined models were 0.789 (range 0.571–0.982), 0.782 (range 0.750–0.911), and 0.868 (range 0.786–0.929), respectively. …”
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Identification of subgroups of early-stage mycosis fungoides patients with increased itch and impaired quality of life by Julia Nenonen, Anna H. Winther, Anna H. Winther, Pontus Jonsson, Pontus Jonsson, Lina U. Ivert, Lina U. Ivert, Hanna Brauner, Hanna Brauner

“…Early MF patients with plaques vs only patches reported impaired EQ-5D index (median 0.725 vs 0.848, p = 0.0032) and increased itch (median VAS 3.27 vs 0.43, p = 0.0006). …”
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Exploration of the ecology and ex-situ conservation of Betula utilis D. Don: Insights from topography, edaphic factors, and nursery management practices by P.A. Sofi, T.H. Masoodi, Nazir A. Pala, Muhammad Waheed, Saud Alamri, Shaista Khan, Khaled A. Alakeel, Shiekh Marifatul Haq, Rainer W. Bussmann

“…The satellite data observations on resource mapping showed the scattered distribution of B. utilis dominated forests at higher elevations within the Sindh Forest division in patches. B. utilis dominated forests are distributed over an area of 2746.58 ha (1.67 %) of the total 164,236.82 ha) geographical area of the division which makes its conservation highly significant. …”
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High-Gain Miniaturized Multi-Band MIMO SSPP LWA for Vehicular Communications by Tale Saeidi, Sahar Saleh, Nick Timmons, Christopher McDaid, Ahmed Jamal Abdullah Al-Gburi, Faroq Razzaz, Saeid Karamzadeh

“…The proposed antenna addresses key challenges in 5G low- and high-frequency bands, including millimeter-wave communication, by integrating innovative features such as a periodic Spoof Surface Plasmon Polariton Transmission Line (SSPP-TL) and logarithmic-spiral-like semi-circular strip patches parasitically fed via orthogonal ports. These design elements facilitate stable impedance matching and wide impedance bandwidths across operating bands, which is essential for vehicular networks. …”
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Analysis on High Temperature Corrosion of Water-Wall in a 440 t/h Boiler Under Low-NOx Combustion Mode by Yibin WANG, Sicong ZHANG, Houzhang TAN, Guohui LIN, Meng WANG, Xuchao LU, Hao YANG

“…The cracks were first formulated at the corroded layer adjacent to iron matrix and then as the cracks developed, it started to break into small patches. Various kinds of pyrrhotite with different crystal sizes would be generated and some gaseous sulfur would be released as the pyrite migrated toward the outer layer, which suggests that gaseous sulfur may play an important role in corrosive process. …”
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The Coral Reefs and Fishes of St. Brandon, Indian Ocean Archipelago: Implications for Sustainable Fisheries by Melanie Ricot, Sruti Jeetun, Shakeel Yavan Jogee, Deepeeka Kaullysing, Nawsheen Taleb-Hossenkhan, Maina Joseph Mbui, Beatriz Estela Casareto, Yoshimi Suzuki, Diah Permata Wijayanti, Ranjeet Bhagooli

“…The benthic composition exhibited clusters, revealing the distinct separation of Chaloupe which predominantly featured sand (75.26%) interspersed with sporadic coral patches characterized by live and dead corals and rubble. …”
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