Preclinical efficacy of a modified gamma-globin lentivirus gene therapy in Berkeley sickle cell anemia mice and human xenograft models by Archana Shrestha, Devin M. Pillis, Sydney Felker, Mengna Chi, Kimberly Wagner, Oluwabukola T. Gbotosho, Joseph Sieling, Mohammad Shadid, Punam Malik

“…We also generated an insulated version of this LV, GbGMI, inserting a 36-bp insulator from the Foamy virus in the long terminal repeats of the LV. Preclinical batches of GbGM and GbGMI LV showed both were highly efficacious in correcting SCA in mice, with sustained gene transfer in primary transplanted SCA mice and high hematopoietic stem cell (HSC) transduction in colony-forming unit-spleen in secondary transplanted mice. …”
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Force Degradation of Intermaxillary Latex Elastics: Comparative In Vitro and In Vivo Study by Lucie Ptáčková, Barbora Ličková, Wanda Urbanová, David Sluka, Klaudia Portašíková, Soňa Chamlarová, Iva Voborná, Ivana Dubovská

“…Materials and Methods IE 3/16″ medium Dentaurum from five different batches of packaging were analyzed. The in vivo study involved 10 volunteers, of which 100 IE were examined. …”
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Study of the Biochemical Biodiversity of Camel Milk by Sara Bouhaddaoui, Rachida Chabir, Faouzi Errachidi, Lahsen El Ghadraoui, Bouchra El Khalfi, Meryem Benjelloun, Abdelaziz Soukri

“…To achieve this aim, three batches of samples of camel milk were collected from various regions (Dakhla, Errachida, and Fès-Meknes) undergoing physicochemical and biochemical analyses. …”
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One size does not fit all: revising traditional paradigms for assessing accuracy of QSAR models used for virtual screening by James Wellnitz, Sankalp Jain, Joshua E. Hochuli, Travis Maxfield, Eugene N. Muratov, Alexander Tropsha, Alexey V. Zakharov

“…Importantly, hit rates were estimated for top scoring compounds organized in batches of the size of plates (for instance, 128 molecules) used in the experimental high throughput screening. …”
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Assessing Risks and Innovating Traceability in Campania’s Illegal Mussel Sale: A One Health Perspective by Valeria Vuoso, Attilio Mondelli, Carlotta Ceniti, Iolanda Venuti, Giorgio Ciardella, Yolande Thérèse Rose Proroga, Bruna Nisci, Rosa Luisa Ambrosio, Aniello Anastasio

“…The illegal sale of mussels is a persistent problem for food safety and public health in the Campania region, where bivalve molluscs are often sold without traceability, evading regulatory controls. In this study, ten batches of mussels seized from unauthorized vendors were analyzed to evaluate their microbiological safety and trace their geographical origin. …”
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Buserelin shortens the estrus-to-ovulation interval and improves the pregnancy outcomes in gilts treated with a fixed-time artificial insemination by Zhicheng Shi, Zhicheng Shi, Zhicheng Shi, Zhicheng Shi, Zhicheng Shi, Zongyu Wang, Zongyu Wang, Zongyu Wang, Zongyu Wang, Zongyu Wang, Lei An, Lei An, Lei An, Lei An, Lei An, Zhi Li, Linghua Cheng, Yuan Yue, Min Guo, Xiaodong Wang, Haiqing Liu, Li Ren, Jianhui Tian, Jianhui Tian, Jianhui Tian, Jianhui Tian, Jianhui Tian, Qin Li, Qin Li, Qin Li, Qin Li, Qin Li, Shumin Wang, Shumin Wang, Shumin Wang, Shumin Wang, Shumin Wang

“…In the present study, we focused on the estrus-to-ovulation interval, a key component in fertility management programs, and directly compared the follicular dynamics and timing of ovulation, and the subsequent pregnancy outcomes between two well-established GnRH analogs buserelin and gonadorelin. 224 prepubertal Large White gilts, randomly divided into three independent batches, were allotted to this study. The administration of PMSG was aligned with the FTAI protocol, with gonadorelin or buserelin injections administered upon detection of estrus onset in gilts. …”
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Study on mechanical characteristics of cemented backfill under dynamic load by Beijing XIE, Xiaoxu LI, Tianyu LIANG, Mingjin CHEN, Siyu CHEN, Feiqi WU

“…To study the mechanical characteristics of cemented backfill with different batching ratio and mass fraction conditions under impact loading, a 50 mm rod diameter split Hopkinson pressure bar test device was used to carry out impact loading tests on the cemented backfill, and at the same time, according to the results of the SHPB experiments, the damage process of the cemented backfill and coal rock affected by the impact pressure in the underground backfill mining was simulated with the help of Holmquist-Johnson-Cook (HJC) model. …”
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Non-Destructive Detection Method of Apple Watercore: Optimization Using Optical Property Parameter Inversion and MobileNetV3 by Zihan Chen, Haoyun Wang, Jufei Wang, Huanliang Xu, Ni Mei, Sixu Zhang

“…To determine whether different batches of apples are suitable for long-term storage or long-distance transportation, and to classify the apples according to quality level to enhance the economic benefits of the apple industry, it is essential to conduct non-destructive testing for watercore. …”
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The IMproving treatment decisions for Patients with AortiC stenosis Through Shared Decision Making (IMPACT SDM) Study: study protocol for a cluster randomized stepped wedge trial by Karen Sepucha, Sammy Elmariah, K. D. Valentine, Matthew A. Cavender, Yuchiao Chang, Chandan M. Devireddy, Neal W. Dickert, Kristy D. Gama, Christopher E. Knoepke, Ethan Korngold, Dharam J. Kumbhani, Daniel D. Matlock, John C. Messenger, Susan Strong, Vinod H. Thourani, Ashwin Nathan, Nishath Quader, Alexander A. Brescia

“…Methods The study is a hybrid type II effectiveness-implementation study using a cluster randomized batched stepped wedge trial with 8 sites across the USA. …”
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Featuring the ovarian morphological of Cichla kelberi Kullander & Ferreira, 2006 introduced in a Basin adjacent to the Lençóis Maranhenses National Park, Northeastern Brazil by D. C. S. Mendes, K. S. Noleto, I. F. S. Carvalho, J. M. Andrade, A. V. Carvalho-Neta, J. R. S. Torres-Júnior, L. M. Costa-Junior

“…Females were classified as synchronous in multiple batches. Germ cells were featured as Primordial Follicles, Primary Development, Cortical Alveoli, Lipid Vitellogenesis, Lipid-Protein Vitellogenesis and Complete Vitellogenesis. …”
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Whey Protein Isolate Hydrogels Containing Cannabidiol Support the Proliferation of Pre-Osteoblasts by Daniel K. Baines, Varvara Platania, Nikoleta N. Tavernaraki, Karen Wright, Maria Chatzinikolaidou, Timothy E. L. Douglas

“…The results suggest that CBD was successfully incorporated into the hydrogels bound potentially through hydrophobic interactions formed between hydrophobic patches of the protein and the hydrophobic cannabinoid. …”
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Mapping stains on flat roofs using semantic segmentation based on deep learning by Lara Monalisa Alves dos Santos, Leonardo Rabero Lescano, Gabriel Toshio Hirokawa Higa, Vanda Alice Garcia Zanoni, Lenildo Santos da Silva, Cesar Ivan Alvarez, Hemerson Pistori

“…In this context, this experimental study aims to analyze deep learning-based semantic segmentation with images obtained from drones to map and monitor damp patches during automated building inspections of flat roof systems. …”
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Identification and characterization of fungi associated with leaf spot/blight and melting-out of turfgrass in Algeria by Nabahat BESSADAT, Bruno HAMON, Nelly BATAILLÉ-SIMONEAU, Nisserine HAMINI-KADAR, Mabrouk KIHAL, Philippe SIMONEAU

“…Symptoms of foliar blight were observed on turfgrass in Oran (Algeria), including yellow chlorotic patches on leaves during the 2020 summer (temperatures between 35 and 40°C). …”
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An amplification mechanism for weak ELF magnetic fields quantum-bio effects in cancer cells by Amirali Zandieh, Seyed Peyman Shariatpanahi, Amir Abas Ravassipour, Javad Azadipour, Maryam Sadat Nezamtaheri, Zahra Habibi-Kelishomi, Mojtaba Ghanizadeh, Ali Same-Majandeh, Keivan Majidzadeh-A, Amir Taheri, Alireza Madjid Ansari, Mohammad Amin Javidi, Mohammad Mehdi Pirnia, Bahram Goliaei

“…We suggest such a resonator can act in two modes for distinct states in cancer cells: (1) cells at the edge of mitochondrial oscillation and (2) cells with local oscillatory patches. When exposed to magnetic fields, the first group exhibits high-amplitude oscillations, while the second group synchronizes to reach a whole-cell oscillation. …”
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Publicly available datasets of breast histopathology H&E whole-slide images: A scoping review by Masoud Tafavvoghi, Lars Ailo Bongo, Nikita Shvetsov, Lill-Tove Rasmussen Busund, Kajsa Møllersen

“…In addition, we compiled 2 lists of breast H&E patches and private datasets as supplementary resources for researchers. …”
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Leveraging SARs and Advanced Deep Learning Techniques for Oil Spill Detection in UAE by M. Alkhalifa, A. Alowais, A. Manousakis, A. Manousakis

“…The system uses an automated Vision Transformer (ViT) as its base for the classification and segmentation of oil spills, which was trained on SAR patches falling under two classes. The step of automating the system involves receiving new data inputs and outputting image segments containing the oil slick without delay. …”
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Landscape Spatiotemporal Heterogeneity Decreased the Resistance of Alpine Grassland to Soil Droughts by Yuxin Wang, Hu Liu, Wenzhi Zhao, Jiachang Jiang, Zhibin He

“…These results underscore the critical role of landscape heterogeneity in modulating grassland responses to drought, suggesting that managing vegetation patches could enhance ecosystem resilience.…”
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The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice by Yingqun Zhou, Kan Chen, Lei He, Yujing Xia, Weiqi Dai, Fan Wang, Jingjing Li, Sainan Li, Tong Liu, Yuanyuan Zheng, Jianrong Wang, Wenxia Lu, Qin Yin, Yuqing Zhou, Jie Lu, Hongfei Teng, Chuanyong Guo

“…After ConA injection, the cytokines IL-2, IL-6, and TNF-α were increased, and Sonic hedgehog (Shh), Glioblastoma- (Gli-) 1, and Patched (Ptc) levels significantly increased. Pretreatment with resveratrol ameliorated the pathologic effects of ConA-induced autoimmune hepatitis and significantly inhibited IL-2, IL-6, TNF-α, Shh, Gli-1, and Ptc. …”
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Oxaliplatin-induced changes in microbiota, TLR4+ cells and enhanced HMGB1 expression in the murine colon. by Vanesa Stojanovska, Rachel M McQuade, Sarah Fraser, Monica Prakash, Shakuntla Gondalia, Rhian Stavely, Enzo Palombo, Vasso Apostolopoulos, Samy Sakkal, Kulmira Nurgali

“…We studied effects of oxaliplatin treatment on 1) TLR4 and high-mobility group box 1 expression within the colon; 2) gastrointestinal microbiota composition; 3) inflammation within the colon; 4) changes in Peyer's patches and mesenteric lymph nodes immune populations in mice. …”
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Domain Adaptation and Fine-Tuning of a Deep Learning Segmentation Model of Small Agricultural Burn Area Detection Using High-Resolution Sentinel-2 Observations: A Case Study of Pun... by Anamika Anand, Ryoichi Imasu, Surendra K. Dhaka, Prabir K. Patra

“…Subsequent fine-tuning using annotated data from Punjab improved the model’s ability to detect small burn patches, demonstrating higher accuracy than the baseline Normalized Burn Ratio (NBR) Index method. …”
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