An active post-marketing surveillance study to evaluate the safety and immunogenicity of Zyvac TCV in healthy participants by Sanjay Vasant Mankar, Chintan Patel, Abhishek Chavan, Ravi Modi, Lisa Sarangi, Virendra Nath Tripathi, Dillip Kumar Dash, Jai Prakash Narayan, Sunil Bandgar, N. Ravi Kumar, Vinay Kumar Gill, Munish Kumar Kakkar, Monjori Mitra, Pavankumar Daultani, Ravindra Mittal, Kapil Maithal, Kevinkumar Kansagra, Deven V. Parmar, Trayambak Dutta, Manish Mahajan, Samir Desai

“…Immunogenicity results demonstrated a seroconversion rate of 94.7% and a significant increase in geometric mean titers from 4.5 U/mL at baseline to 1787.8 U/mL at Day 28. A post-hoc batch analysis showed consistent immunogenicity across three commercial vaccine batches. …”
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Integrated Metabolomics and Lipidomics Analysis Reveals the Mechanism Behind the Action of Chiglitazar on the Protection Against Sepsis-Induced Acute Lung Injury by Liu-Liu Lu, Yu-Li Cao, Zhen-Chen Lu, Han Wu, Shan-Song Hu, Bing-Qing Ye, Jin-Zhi He, Lei Di, Xu-Lin Chen, Zhi-Cheng Liu

“…To validate the mechanism by which chiglitazar protected against SALI, the SIRT1 inhibitor EX-527 was applied to human normal lung epithelial (BEAS-2B) cells and another batch of rats to observe its reverse effect against chiglitazar’s action. …”
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Consolidation and Heavy Metal Adsorption-Desorption Characteristics of Soils with Different Clay Contents by WU Ya-jun, YUE Hao-fan, ZANG Xue-ke, ZHANG Xu-dong, ZHANG Chang-song, WU Jin-hong

“…First, the basic physical properties of soil samples were analyzed, followed by consolidation tests to investigate the porosity ratios, compression characteristics, permeability, and consolidation behaviors of soils with different clay contents, as well as their microscopic characteristics under scanning electron microscope (SEM). Through batch oscillation-centrifugation experiments, the adsorption of heavy metals (Cu and Zn) by the soil samples and their desorption characteristics during heavy metal removal using citric acid were studied, with analysis incorporating pH values and particle size variations. …”
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Identification of QTL for Pre-harvest Sprouting Resistance by Using Chromosome Segment Substitution Lines of Dongxiang Common Wild Rice by Jiaxiao HU, Jin LIU, Xiaoding MA, Hang TU, Huiying ZHOU, Bingxin MENG, Di CUI, Maomao LI, Longzhi HAN, Liqin YU

“…These QTLs formed four QTL clusters (qPHSRC1, qPHSRC2, qPHSRC8 and qPHSRC9), among which qPHSRC2 and qPHSRC9 had higher LOD values, phenotypic contribution rate (%) and additive effect, and qPHSRC2 was a newly discovered major QTL cluster.【Conclusion】A batch of PHS resistant germplasms were screened and 14 QTLs were mapped, four QTL clusters were repeatedly identified, and a new major QTL cluster qPHSRC2 controlling the PHSR was discovered.…”
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The risk of contaminated ultrasound gels in the intensive care unit: lessons from an outbreak of Burkholderia cenocepacia by Beevifatimah Ahamed Sha, Paul Anantharajah Tambyah, Shi Poh Li, Sarathamani Rethenam, Lilibeth Silagan Alenton, Ling Chee Poh, Yuan Sun Yong, Peng Sii Yong, Gabriel Yan Zherong, Lasantha Ratnayake, Michelle Ang, Gerald Chua, Surinder Kaur Pada

“…Immediate actions were taken, including a recall of ultrasound gel batches and the use of sterile gel sachets for high-risk procedures. …”
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Comprehensive genomic study of Plasmodium falciparum in Sierra leone: genetic variation and resistance patterns by Xin-jie Zhan, Shen-Bo Chen, Tian-yu Wang, Yi-wen Duan, Hai-Mo Shen, Jun-Hu Chen, Jing-jing Xie

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Single-cell transcriptome and multi-omics integration reveal ferroptosis-driven immune microenvironment remodeling in knee osteoarthritis by Yushun Wu, Jing Liu, Wenying Yu, Xiaoding Wang, Jian Li, Weiquan Zeng

“…Single-cell data were processed via Seurat (QC: mitochondrial genes >3 MAD; normalization: LogNormalize; batch correction: Harmony) and annotated using CellMarker/PanglaoDB. …”
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Production and characterization of magnetic Biochar derived from pyrolysis of waste areca nut husk for removal of methylene blue dye from wastewater by Syeda Minnat Chistie, Sneha Ullhas Naik, Pragathi Rajendra, Apeksha, Ranjeet Kumar Mishra, Gadah Albasher, Sampath Chinnam, Gautham P. Jeppu, Zeenat Arif, Javaria Hameed

“…The biochar and biomass were characterised via proximate analysis, ultimate analysis, bulk density, heating value, extractive content, biochemical analysis, thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FTIR), SEM, BET surface area, pH, water holding capacity (WHC) and X-ray diffraction (XRD). A semi-batch reactor was used to produce biochar (ANHB) at 600 and 800 oC at 10 oC min− 1 heating rate and 45 min holding time in an inert atmosphere. …”
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Enhanced Erythromycin Elimination from Erythromycin Fermentation Residue via Anaerobic Volatile Fatty Acid Production Under Mesophilic Conditions by Jianjun Ren, Xilong Xia, Honggang Mao, Lixia Zhu, Mohammad J. Taherzadeh, Yiliang Chen, Dongze Niu, Chunyu Li, Rui Tang, Xiancheng Qi, Chuanyang Xu, Dongmin Yin

“…Different parameters were applied to evaluate the effects on energy recovery of VFA together with erythromycin elimination from EFR through batch assays under mesophilic conditions. Results demonstrated that anaerobic digestion technology for VFA production can significantly enhance erythromycin elimination in EFR. …”
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Nitrificação de efluente de abatedouro de tilápia em função da aeração e tempo de reação Nitrification of tilapia slugtherhouse effluent according to the aeration conditions and re... by Dilcemara C. Zenatti, Simone D. Gomes, Ajadir Fazolo, Ricardo N. Costanzi, Salah D. M. Hasan, André L. Gentelini

“…The present study had as its objective the evaluation of the effects of the reaction time (TR) and of the aeration on the removal efficiency of the ammoniacal nitrogen and on the conversion of the ammoniacal nitrogen to nitrate in a nitrification process of the tilapia slaughterhouse effluent in sequential batch reactor with biofilm. The experiment was performed using two reaction times (6 and 12 h) and two levels of air flow (3 and 6 L min-1), four treatments, starting from the combination of these two variables, were evaluated in an experimental planning of the factorial 2² type: being: T4 (QAr = 3 L min-1 and TR = 6); T2 (QAr = 6 L min-1 and TR = 6), T3 (QAr = 3 L min-1 and TR = 12) and T1 (QAr = 6 L min-1 and TR = 12), and four repetitions. …”
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Hetero-Disubstituted Sugarcane Bagasse as an Efficient Bioadsorbent for Cationic Dyes by Megg Madonyk Cota Elias Carvalho, Liliane Catone Soares, Oscar Fernando Herrera Adarme, Gabriel Max Dias Ferreira, Ranylson Marcello Leal Savedra, Melissa Fabíola Siqueira, Eduardo Ribeiro de Azevedo, Leandro Vinícius Alves Gurgel

“…A hetero-disubstituted sugarcane bagasse (HDSB) was prepared by simultaneous one-pot chemical modification of sugarcane bagasse with succinic and phthalic anhydrides. HDSB was used in batch mode for the removal of the cationic dyes auramine-O (AO) and safranin-T (ST) from spiked aqueous solutions. …”
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Mercury capture using functionalized metal-organic framework encapsulated in dual hydrogel layers of β-cyclodextrin and polyethylenimine: Synthesis, characterization, adsorption, t... by Asma O. Obaid, Amnah S. Al Zbedy, Kamelah S. Alrashdi, Meshari M. Aljohani, Sara A. Alqarni, Ameena M. Al-Bonayan, Hana M. Abumelha, Nashwa M. El-Metwaly

“…The synthesis and characterization of the material showed a surface area of 434.42 m²/g, a pore volume of 0.526 cc/g, and an average pore radius of 1.88 nm. Batch experiments analyzed key adsorption parameters: temperature, Hg(II) concentration, adsorbent amount, and contact duration. …”
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Herpes Murine Model as a Biological Assay to Test Dialyzable Leukocyte Extracts Activity by Nohemí Salinas-Jazmín, Sergio Estrada-Parra, Miguel Angel Becerril-García, Alberto Yairh Limón-Flores, Said Vázquez-Leyva, Emilio Medina-Rivero, Lenin Pavón, Marco Antonio Velasco-Velázquez, Sonia Mayra Pérez-Tapia

“…Using this model, we evaluated the activity of 27 Transferon batches. All batches improved the survival of HSV-1-infected mice, wherein average survival rose from 20.9% in control mice to 59.6% in Transferon-treated mice. …”
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Integrative Single-Cell Analysis of Cardiomyopathy Identifies Differences in Cell Stemness and Transcriptional Regulatory Networks among Fibroblast Subpopulations by Wenyang Nie, Zhijie Zhao, Yuhang Liu, Youcao Wang, Jingwen Zhang, Ying Hu, Yang Liu, Yong Wang, Zhen Wang

“…Additionally, the Python package SCENIC was utilized to assess enrichment of transcription factors and activity of regulators within cardiac fibroblast subpopulations in cardiomyopathy. Results. Following batch effect correction, 179,927 cells were clustered into 32 clusters, designated as T_NK cells, endothelial cells, myeloid cells, fibroblasts, pericytes, SMCs, CMs, proliferating cells, EndoCs, and EPCs. …”
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TSPAN4+ fibroblasts coordinate metastatic niche assembly through migrasome-driven metabolic reprogramming and stromal-immune crosstalk in pancreatic adenocarcinoma by Qingwen Hu, Qingwen Hu, Jiali Chen, Yang Liu, Yang Liu, Haiqing Chen, Haotian Lai, Lai Jiang, Xuancheng Zhou, Shengke Zhang, Jinbang Huang, Hao Chi, Bo Li, Xiaolin Zhong

“…Data from the GEO and TCGA databases were integrated and processed using batch correction techniques. Single-cell data were analyzed with Seurat and Monocle for dimensionality reduction and pseudotime trajectory analysis. …”
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A Cross-Sectional Exploratory Study of Rat Sarcoid (Ras) Activation in Women with and Without Polycystic Ovary Syndrome by Sara Anjum Niinuma, Haniya Habib, Ashleigh Suzu-Nishio Takemoto, Priya Das, Thozhukat Sathyapalan, Stephen L. Atkin, Alexandra E. Butler

“…<b>Methods</b>: In a well-validated PCOS database of 147 PCOS and 97 control women, plasma was batch analyzed using Somascan proteomic analysis for circulating KRas, Ras GTPase-activating protein-1 (RASA1), and 45 growth factor-related proteins. …”
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Optimization of the Canopy Three-Dimensional Reconstruction Method for Intercropped Soybeans and Early Yield Prediction by Xiuni Li, Menggen Chen, Shuyuan He, Xiangyao Xu, Panxia Shao, Yahan Su, Lingxiao He, Jia Qiao, Mei Xu, Yao Zhao, Wenyu Yang, Wouter H. Maes, Weiguo Liu

“…The optimized pipeline enabled batch extraction of 23 canopy structural parameters, achieving high accuracy, with linear fitting R² values of 0.990 for plant height and 0.950 for plant width. …”
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Associations of absolute risk of osteoporotic fractures (FRAX®) and total cardiovascular risk (SCORE) in urban population of the Russian Federation by M. A. Myagkova, I. A. Skripnikova, O. V. Kosmatova, S. A. Shalnova, V. A. Vygodin

“…Over the next 10 years, OPF AR was calculated on the basis of the Russian FRAX® model without taking into account the bone mineral density using batch processing. To assess the total CVR, the SCORE scale was used for countries with a high risk of cardiovascular disease in people &lt;65 years of age. …”
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Identification of cellular signatures associated with chinese hamster ovary cell adaptation for secretion of antibodies by Ying Bai, Ivan Domenech Mercadé, Ramy Elgendy, Giulia Lambiase, Sew Peak-Chew, Catarina Franco, Steven W. Wingett, Tim J. Stevens, Luigi Grassi, Noah Hitchcock, Cristina Sayago Ferreira, Diane Hatton, Elizabeth A. Miller, Rajesh K. Mistry

“…Gene and protein expression profiles of CHO cell pools and clones producing a panel of different monoclonal and bispecific antibodies were analysed during fed-batch production. Antibody-expressing CHO cell pools were heterogeneous, resulting in few discernible genetic signatures. …”
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Changes in DNA methylation are associated with systemic lupus erythematosus flare remission and clinical subtypes by Mary K. Horton, Joanne Nititham, Kimberly E. Taylor, Patricia Katz, Chun Jimmie Ye, Jinoos Yazdany, Maria Dall’Era, Charlotte Hurabielle, Lisa F. Barcellos, Lindsey A. Criswell, Cristina M. Lanata

“…We identified sites where methylation change between visits was associated with remission at the follow-up visit using limma package and a time x remission interaction term. Models adjusted for batch, age at diagnosis, time between visits, age at flare, sex, medications, and cell-type proportions. …”
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