Selective amino acid formulation enhances anion secretion and restores function in cystic fibrosis mutations by Astrid Grosche, Anusree Sasidharan, Matthias Salathe, Nathalie Baumlin, Damiano Angoli, Sreekala Prabhakaran, Xiaodong Xu, Sadasivan Vidyasagar

“…Benzamil-insensitive current was sequentially inhibited to determine the contributions of SLC26A9, CFTR, ANO1, and NKCC1. 36Cl unidirectional and net fluxes (JnetCl) validated chloride secretion. Whole-cell patch-clamp studies determined the current density with SAA in WT- and CF-HBEC. …”
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Parametric Rule-Based Intelligent System (PRISM) for Design and Analysis of High-Strength Separable Microneedles by Sanghwi Ju, Seung-hyun Im, Kyungsun Seo, Junhyeok Lee, Seokjae Kim, Tongil Park, Taeksu Lee, Byungjeon Kang, Jayoung Kim, Ryong Sung, Jong-Oh Park, Doyeon Bang

“…However, designing high-strength separable microneedles, which enable easy skin penetration and easy patch detachment, is challenging. Here, we present a Parametric Rule-based Intelligent System (PRISM), which generates the design of and analyzes high-strength separable microneedles. …”
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Persistent monitoring of insect-pests on sticky traps through hierarchical transfer learning and slicing-aided hyper inference by Fateme Fotouhi, Fateme Fotouhi, Kevin Menke, Aaron Prestholt, Ashish Gupta, Matthew E. Carroll, Hsin-Jung Yang, Edwin J. Skidmore, Matthew O’Neal, Nirav Merchant, Sajal K. Das, Peter Kyveryga, Baskar Ganapathysubramanian, Baskar Ganapathysubramanian, Asheesh K. Singh, Arti Singh, Soumik Sarkar, Soumik Sarkar

“…Moreover, slicing-aided hyper inference subdivides images into overlapping patches, conducting independent object detection on each patch before merging outcomes for precise, comprehensive results.ResultsThe outcomes underscore the substantial improvement achievable in detection results by integrating a diverse and expansive in-domain dataset within the HTL method, complemented by the utilization of SAHI.DiscussionWe also present a hardware and software infrastructure for deploying such models for real-life applications. …”
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The impact of Poyang Lake water level changes on the landscape pattern of wintering wading bird habitats by Feihong Yu, Jiancheng Zhai, Zhiqiang Huang, Jimei Chen, Fuqiang Han, Liaobo Wang

“…When 6.83 ≤WL→WLx m, wading bird habitats become increasingly fragmented, with habitat patch type diversity, evenness, and connectivity gradually improving. …”
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Multi-biosensing hairband for emergency health assessment by Ming Li, Ganghua Li, Tong Xu, Yiwen Wang, Ruidong Xu, Xinwei Zhang, Fuxing Chen, Ning Yu, Mingwei Tian

“…By integrating the multi-biosensors and a circuit patch into the textile substrate, a wireless hairband system is constructed for tracking human physiological dynamics. …”
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Abstract 284: Renal Contrast Excretion After Myelography: A Valuable Tool in The Diagnosis of Cerebrospinal‐Venous Fistulae by Firas Bounni, Neil V. Patel, Emanuele Orru

“…One fistula was treated via CT‐guided targeted blood patch and fibrin glue injection and the other via endovascular Onyx embolization of the tributary Intercostal veins. …”
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Xenograft of bio-3D printed scaffold-free cartilage constructs derived from human iPSCs to regenerate articular cartilage in immunodeficient pigs by Toshihiro Nonaka, Anna Nakamura, Daiki Murata, Hiromu Yoshizato, Shohei Kashimoto, Yukiko Nagaishi, Manabu Itoh, Denise Zujur, Chengzhu Zhao, Yoshiko Inada, Makoto Ikeya, Junya Toguchida, Masaaki Mawatari, Koichi Nakayama

“…The constructs were partially cut open to form a patch and implanted into osteochondral defects in the femoral trochlear groove of immunodeficient miniature pigs. …”
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Analysis of ecological network evolution in an ecological restoration area with the MSPA-MCR model: A case study from Ningwu County, China by Ziyan Guo, Chuxin Zhu, Xiang Fan, Muye Li, Nuo Xu, Yuan Yuan, Yanjun Guan, Chunjuan Lyu, Zhongke Bai

“…With the expansion of the area, the original 6 ecological source patches merged into 4 in 2010 and then 3 in 2020, and 1 new patch emerged in 2010 and 5 more patches in 2020. (2) The area of high ecological resistance showed a minor increase from 2000 (576.90 km2) to 2010 (592.31 km2), but then declined sharply by 38.53 % in 2020 (364.07 km2). (3) With the emergence of new ecological source patches, more corridors were needed to connect them. …”
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Single staged repair of an anastomotic tracheal fistula following Mckeown esophagectomy via cervical incision: a case report by Haoqian Zheng, Chenyang Guo, Yadi Zhang, Hang Gu, Yinzhi Zhao, Run Xiang, Wei Dai, Xing Wei, Tianpeng Xie, Qiang Li, Xiang Wang

“…Surgical repair methods for TEF include muscle or omental flap support, biologic patch repair, and sleeve resection. In recent years, there has been an increasing number of case reports on primary closure via a cervical incision, with a rising success rate and a lower incidence of postoperative complications. …”
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Robust Video List Decoding in Error-Prone Transmission Systems Using a Deep Learning Approach by Yujing Zhang, Stephane Coulombe, Francois-Xavier Coudoux, Alexis Guichemerre, Patrick Corlay

“…Three new components are defined and used in the Transformer-assisted image quality evaluation metric: neighborhood-based patch fidelity aggregation, discriminant color texture transformation and ranking-constrained penalty loss function. …”
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Landscape Analysis and Assessment of Ecosystem Stability Based on Land Use and Multitemporal Remote Sensing: A Case Study of the Zhungeer Open-Pit Coal Mining Area by Yinli Bi, Tao Liu, Yanru Pei, Xiao Wang, Xinpeng Du

“…Following rehabilitation efforts, the landscape patch density, landscape separation, and landscape fragmentation in the Zhungeer open-pit coal mining area exhibited a declining trend, leading to a more uniform distribution of landscape patches and improved structural balance. …”
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Utilizing Vision Transformers for Predicting Early Response of Brain Metastasis to Magnetic Resonance Imaging-Guided Stage Gamma Knife Radiosurgery Treatment by Simona Ruxandra Volovăț, Diana-Ioana Boboc, Mădălina-Raluca Ostafe, Călin Gheorghe Buzea, Maricel Agop, Lăcrămioara Ochiuz, Dragoș Ioan Rusu, Decebal Vasincu, Monica Iuliana Ungureanu, Cristian Constantin Volovăț

“…The vision transformer (ViT) model employed in this study processes MRIs as sequences of patches, enabling the capture of localized tumor features critical for early response prediction. …”
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Impact of landscape patterns on river water quality: Spatial-scale effects across an agricultural-urban interface by Kun Mei, Haonan Shi, Yupeng Wu, Randy A. Dahlgren, Xiaoliang Ji, Minmin Yang, Yueru Guan

“…Overall, the dynamic subwatershed scale showed the strongest explanatory power for water quality indicators, with 91.2 % for the rainy season and 83.2 % for the dry season. The largest patch index of agricultural land (A_LPI) and water bodies (W_LPI) were identified as the most critical landscape indices influencing water quality at the dynamic sub-watershed scale, with threshold values for these indices established as A_LPI < 10 % and W_LPI > 1.5 %. …”
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Kir6.1, a component of an ATP-sensitive potassium channel, regulates natural killer cell development by Natalie Samper, Lilja Hardardottir, Delphine M. Depierreux, Soomin C. Song, Ayano Nakazawa, Ivan Gando, Tomoe Y. Nakamura, Andrew M. Sharkey, Carla R. Nowosad, Stefan Feske, Francesco Colucci, William A. Coetzee, William A. Coetzee, William A. Coetzee

“…Kcnj8 expression is highest in the most mature subset of splenic NK cells (CD27-/CD11b+) and in NKG2A+ or Ly49C/I+ educated uterine NK cells. Using patch clamping, we show that a subset of NK cells expresses a current sensitive to the Kir6.1 blocker PNU-37883A. …”
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“Modified sandwich” technique in the surgery of acute type A aortic dissection by Jiajie Kong, Tong Liu, Shuqiang Xi, Zhaobin Li, Zeyue Jin, Fan Yang, Zhe Zhu, Lei Liu

“…This study aims to evaluate the efficacy of the modified “sandwich” technique using a synthetic vascular patch for aortic root reconstruction in acute type A aortic dissection surgery. …”
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An mRNA Vaccine for Herpes Zoster and Its Efficacy Evaluation in Naïve/Primed Murine Models by Linglei Jiang, Wenshuo Zhou, Fei Liu, Wenhui Li, Yan Xu, Zhenwei Liang, Man Cao, Li Hou, Pengxuan Liu, Feifei Wu, Aijun Shen, Zhiyuan Zhang, Xiaodi Zhang, Haibo Zhao, Xinping Pan, Tengjie Wu, William Jia, Yuntao Zhang

“…The manufactured and lyophilized patch of CVG206 demonstrated good thermal stability at 2–8 °C during 9 months of storage. …”
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MicroRNA: a clinician’s view of the state of the problem. Part 3: MicroRNA and approaches to the treatment of cardiovascular diseases by O. Iu. Mironova, M. V. Berdysheva, E. S. Deeva, E. M. Elfimova

“…For this purpose, a biocompatible patch with microneedles (MI) with antifibrotic activity based on microRNA can be used to prevent excessive  cardiac fibrosis after myocardial infarction. …”
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Zingerone alleviates inflammatory pain by reducing the intrinsic excitability of anterior cingulate cortex neurons in a mice model by Yuanyuan Wang, Yuanyuan Wang, Yuanyuan Wang, Lang Dong, Lang Dong, Shu Han, Yuehan You, Mingrui Zhang, Bingjing Sun, Bingjing Sun, Hong Ni, Hong Ni, Rongjing Ge, Rongjing Ge, Jianhong Liu, Jianhong Liu, Jiandong Yu, Jiandong Yu, Jiandong Yu

“…In vivo fiber photometry and whole-cell patch clamp techniques were employed to investigate the potential mechanisms.ResultsBoth acute and long-term treatment with zingerone resulted in a significant increase in mechanical and thermal pain thresholds in mice experiencing CFA-induced inflammatory pain. …”
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LRRC8A in endothelial cells contributes to the aberrant blood-brain barrier integrity in ischaemic stroke by Yan Wang, Yan Zhang, Chang Liu, Xiaoyu Zhang, Bo Wang, Yue Kong, Hailin Zhang, Yanfei Tian, Yupeng Zhao, Zhenghui Wu, Huaxing Zhang, Xiaona Du, Huiran Zhang

“…Primary mouse and human brain microvascular endothelial cells (m/hBMVECs) were subjected to oxygen-glucose deprivation (OGD) and re-oxygenation for varying durations. Patch-clamp recordings were performed to measure volume-regulated chloride currents. …”
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New Insights Concerning Phytophotodermatitis Induced by Phototoxic Plants by Cristina Grosu (Dumitrescu), Alex-Robert Jîjie, Horaţiu Cristian Manea, Elena-Alina Moacă, Andrada Iftode, Daliana Minda, Raul Chioibaş, Cristina-Adriana Dehelean, Cristian Sebastian Vlad

“…Moreover, the most used approaches and tests for accurate diagnosis such as patch testing, Wood’s lamp examination, or skin biopsy are presented. …”
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