A 3D Clinical Face Phenotype Space of Genetic Syndromes Using a Triplet-Based Singular Geometric Autoencoder by Soha S. Mahdi, Eduarda Caldeira, Harold Matthews, Michiel Vanneste, Nele Nauwelaers, Meng Yuan, Giorgos Bouritsas, Gareth S. Baynam, Peter Hammond, Richard Spritz, Ophir D. Klein, Michael Bronstein, Benedikt Hallgrimsson, Hilde Peeters, Peter Claes

“…Experiments are designed to illustrate the following properties of CFPSs that can aid clinicians in narrowing down their search space: a CFPS can 1) classify syndromes accurately, 2) generalize to novel syndromes, and 3) preserve the relatedness of genetic diseases, meaning that clusters of phenotypically similar disorders reflect functional relationships between genes. The proposed model consists of three main components: an encoder based on GDL optimizing distances between groups of individuals in the CFPS, a decoder enhancing classification by reconstructing faces, and a singular value decomposition layer maintaining orthogonality and optimal variance distribution across dimensions. …”
Get full text

Pathophysiological Significance of Urea in Glomerular Filtration Dysregulation in Hepatorenal Syndrome: An Integrative Review by Anatoliy Gozhenko, Walery Zukow, Olena Gozhenko, Olga Kvasnytska

“…Future research should focus on elucidating molecular mechanisms of urea’s regulatory functions, defining optimal concentration ranges in pathology, and developing targeted therapeutic strategies based on these concepts.…”
Get full text

Patient Perspectives of Center-Specific Reporting in Kidney Failure Care: An Australian Qualitative Study by Emily Duncanson, Christopher E. Davies, Shyamsundar Muthuramalingam, Effie Johns, Kate McColm, Matty Hempstalk, Zoran Tasevski, Nicholas A. Gray, Stephen P. McDonald

“…Results: Patients from all Australian states and territories participated, with 22 (81%) having a functioning kidney transplant and 22 (81%) having current or previous experience of dialysis. …”
Get full text

Interlacing biology and engineering: An introduction to textiles and their application in tissue engineering by S. Scholpp, L.A. Hoffmann, E. Schätzlein, T. Gries, C. Emonts, A. Blaeser

“…With in-depth knowledge, textiles can be tailored to obtain specific mechanical properties as accurately as possible and aid the formation of functional tissue. However, as textile structures inherently differ from biological tissues, careful optimization is required to enhance cell behavior, mechanical performance, and clinical applicability.This review is intended for TE experts interested in using textiles as scaffolds and provides a detailed analysis of the available options, their characteristics and known applications. …”
Get full text

Effectiveness of eHealth for Medication Adherence in Renal Transplant Recipients: Systematic Review and Meta-Analysis by Lili Zhou, Ke Cheng, Linbin Chen, Xinyi Hou, Jingjing Wan

“… BackgroundAs the optimal treatment for end-stage renal disease, kidney transplantation has proven instrumental in enhancing patient survival and quality of life. …”
Get full text

ANALYSIS OF HEART RATE VARIABILITY IN PATIENTS WITH PERSISTENT ATRIAL FIBRILLATION by M. I. Fushtey, O. V. Soloviov, E. V. Sid’

“…The analysis of HRV allows you to make a more precise choice of drug and find it more optimal dose. Given the lack of uniform standards of HRV in patients with coronary artery disease should be analyzed the dynamics of these parameters during treatment compared with baseline data. …”
Get full text

Laboratory Study on a New Composite Plugging Material with High Bearing Strength and High-Temperature Resistance by Xiaoming Su, Zhanghua Lian, Hanqiao Xiong, Yuan Yuan, Junwei Fang

“…The reservoir in the Central Tarim Basin is a typical high-pressure fracture-vuggy carbonate reservoir with high temperatures, which easily leads to drilling fluid losses and the high-temperature carbonate. The conventional lost circulation materials (LCMs) cannot meet the reservoir. …”
Get full text

Orthokeratology for myopia control: a three-year longitudinal study on axial length modulation influenced by baseline age and spherical equivalent by Xiaoxue Hu, Zixun Wang, Boxuan Sun, Xiang Wan, Feng Chang, Weiping Lin, Ruihua Wei

Get full text

Novel deep learning for multi-class classification of Alzheimer’s in disability using MRI datasets by Sumaiya Binte Shahid, Maleeha Kaikaus, Md. Hasanul Kabir, Mohammad Abu Yousuf, A. K. M. Azad, A. S. Al-Moisheer, Naif Alotaibi, Salem A. Alyami, Touhid Bhuiyan, Mohammad Ali Moni, Mohammad Ali Moni, Mohammad Ali Moni

“…IntroductionAlzheimer’s disease (AD) is one of the most common neurodegenerative disabilities that often leads to memory loss, confusion, difficulty in language and trouble with motor coordination. …”
Get full text

Approach to shoulder instability: a randomized, controlled trial by Julien Caron, MD FRCSC, Kellen Walsh, MD FRCSC, Tinghua Zhang, MSc, Rashed AlAhmed, MBChB MSc FRCSC, Peter B. MacDonald, MD FRCSC, Cristina Bassi, MD, J Whitcomb Pollock, MD FRCSC MSc, Katie McIlquham, BSc, Peter Lapner, MD FRCSC

“…The instability severity index Score (ISI score) is a point-based algorithm that may be used to assist clinicians in selecting the optimal treatment approach, but its efficacy compared with a traditional treatment algorithm has not been previously validated. …”
Get full text

Gradient hydrogels based on photo-initiated polymerization-induced self-assembly by Yingchu Zhou, Ziqi Liu, Yi Zeng, Li Luo, Jie Chen, Diyuan Zheng, Zhao Wu, Chao Lang

Get full text

Effects of nitrogen, phosphorous, and potassium fertilization on rapeseed yield under freeze stress by Shishi Liu, Linxin Xiong, Wen Fang, Kunkun Wang, Xin Cui, Chen Liu, Tao Ren, Jianwei Lu

“…In 2023–2024, a severe freeze event caused yield losses ranging from 13.4% to 63.3%, depending on nutrient fertilizer rates and sites. …”
Get full text

Flow-based Text Style Transfer Model by Zihan ZHANG, Jinqiao DAI, Pin YANG

“…Minimizing textual information loss during the transfer process remains critical to resolving content-style matching issues and preserving core semantics.Method This study introduces a flow-based text style transfer model. …”
Get full text

Mild water deficit during maturity reduces cracking rate of greenhouse muskmelon while improving fruit quality by Qimin Xue, Hao Li, Taisheng Du

“…The comprehensive quality score based on principal component analysis and membership function method revealed that severe DI applied at entire reproductive period had optimal comprehensive quality score. …”
Get full text

Nanoscaffold Ba0.6Sr0.4TiO3:Nd2O3 ferroelectric memristors crossbar array for neuromorphic computing and secure encryption by Weifeng Zhang, Jikang Xu, Yongrui Wang, Yinxing Zhang, Yu Wang, Pengfei Li, Yongqing Jia, Zhen Zhao, Changliang Li, Biao Yang, Yue Hou, Zhenqiang Guo, Zeze Huang, Yincheng Qi, Xiaobing Yan

“…Here, we introduce a silicon-based integrated (Ba0.6Sr0.4TiO3)0.5(Nd2O3)0.5 (BSTN) nanoscaffolded ferroelectric thin film memristor with a vertically self-assembled nanocomposite structure (VSNs) optimally oriented on La0.67Sr0.33MnO3/SrTiO3/PSi substrates. …”
Get full text

Analysis of the patients' quality of life after radical cystectomy with the orthotopic neobladder or ileal conduit formation by S. V. Kotov, A. L. Khachatryan, D. P. Kotova, A. K. Zhuravleva, Sh. M. Sargsyan, D. M. Magomedov

“…Orthotopic neobladder or ileal conduit are the most optimal and common methods of intestinal urine diversion. …”
Get full text

Effect of Diet Supplementation with Two Yeast Cultures on Rumen Fermentation Parameters and Microbiota of Fattening Sheep In Vitro by Gulinizier Nueraihemaiti, Xiangdong Huo, Huiying Zhang, Honglin Shi, Yan Gao, Jun Zeng, Qing Lin, Kai Lou

“…Notably, YC significantly increased the relative abundance of functional microbial communities compared to XP. These findings provide a theoretical and practical foundation for optimizing the large-scale breeding of Hu sheep.…”
Get full text

Mitigating enteric methane emissions: An overview of methanogenesis, inhibitors and future prospects by Xin Xie, Yurong Cao, Qiushuang Li, Qi Li, Xingze Yang, Rong Wang, Xiumin Zhang, Zhiliang Tan, Bo Lin, Min Wang

“…Methanogenesis inhibitors, when used in conjunction with nutritional and breeding management strategies, are widely regarded as effective additives for optimizing rumen function, enhancing nutrient utilization and reducing enteric methane emissions. …”
Get full text

COMPARATIVE CHARACTERISTICS OF THE EFFECTIVENESS OF DIRECT AND INDIRECT RESTORATIONS ON TEETH WITH DISCOLORATION by I.V. Zhyvotovskyi, Yu.I. Sylenko, M.V. Khrebor

“…The total number of complications was 17%, which indicates the need to find the optimization approaches to treatment with these structures. …”
Get full text

Regulation of land use conflicts at indigenous peoples lands based on blockchain platform, russian arctic case study by A. V. Evseev, T. M. Krasovskaya, V. S. Tikunov, I. N. Tikunova

“…Blockchain solution presented here may promote sustainable pattern of the Arctic zone pioneer economic development regarding indigenous population well-being and ensure optimal use of its nature capital via public-private collaboration.…”
Get full text