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81
REM sleep is associated with white matter integrity in cognitively healthy, older adults.
Published 2020-01-01“…There is increasing awareness that self-reported sleep abnormalities are negatively associated with brain structure and function in older adults. …”
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82
Alteration of fractional anisotropy in preterm-born individuals: a systematic review and meta-analysis
Published 2024-12-01“…Diffusion tensor imaging (DTI) studies using tract-based spatial statistics (TBSS) effectively detect microstructural white matter (WM) abnormalities in the brain. …”
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83
Large-scale EM data reveals myelinated axonal changes and altered connectivity in the corpus callosum of an autism mouse model
Published 2025-04-01“…Notably, these ultrastructural alterations were widespread across the corpus callosum, suggesting a global disruption of myelinated axon integrity.DiscussionThis study provides novel insights into the microstructural abnormalities of the corpus callosum in ASD mouse, supporting the hypothesis that myelination deficits contribute to ASD-related communication impairments between brain hemispheres. …”
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84
Clinical Findings of Melanoma-Associated Retinopathy with anti-TRPM1 Antibody
Published 2021-01-01“…Anti-TRPM1 autoantibodies were detected in a patient diagnosed with MAR who had negative flash ERG and retinal microstructural abnormalities, and the impairment did not recover during the follow-up period. …”
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85
Harmonization of multi-center diffusion tensor tractography in neonates with congenital heart disease: Optimizing post-processing and application of ComBat
Published 2022-09-01“…Few harmonization techniques have been developed for neonatal brain microstructural (diffusion tensor) analysis. The work presented here aims to remedy two common problems that exist with the current state of the art approaches: 1) variance in scanner and protocol in data collection can limit the researcher's ability to harmonize data acquired under different conditions or using different clinical populations. 2) The general lack of objective guidelines for dealing with anatomically abnormal anatomy and pathology. …”
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86
Association of bone mineral density and trabecular bone score with cardiovascular disease
Published 2020-01-01“…One explanation is that bone microstructural remodeling becomes more active during early coronary calcification. …”
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87
Fiber tract integrity in patients with brain injury and chronic health symptoms
Published 2021-12-01“…Patients with traumatic brain injuries (TBI), especially those with chronic health symptoms, often experience behavioral impairments attributable to white matter (WM) microstructural degeneration. Diffusion tensor imaging (DTI) is sensitive to these WM abnormalities, which are frequently a consequence of diffuse axonal injuries precipitated by the original trauma. …”
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88
Role of Optical Coherence Tomography on Corneal Surface Laser Ablation
Published 2012-01-01“…OCT is an optical imaging modality that uses low-coherence interferometry to provide noninvasive cross-sectional imaging of tissue microstructure in vivo. There are two types of OCTs, each with transverse and axial spatial resolutions of a few micrometers: the time-domain and the fourier-domain OCTs. …”
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89
Macroscopic brain region and network changes in a central-arterial-stiffness rat model
Published 2025-09-01“…Ex vivo diffusion tensor imaging revealed microstructural changes in the limbic region, including the hippocampus. …”
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90
Clinical approaches to osteoporosis in patients with chronic kidney disease: A comprehensive review
Published 2025-08-01“…This condition is compounded by disruption of bone metabolic turnover, abnormalities in bone microstructure and collagen cross-linking, and compromised bone quality, all of which contribute to increased bone fragility. …”
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91
Investigating the role of structural connectivity in the individuals with moderate hearing loss
Published 2024-12-01“…Previous studies have found white matter abnormalities in individuals with hearing loss, but the structural connectivity and microstructural properties of white matter in individuals with moderate hearing loss remain unclear.To examine the integrity of white matter, identify vulnerable structural connectivity, and assess network topology, we examined major white matter tracts in elderly individuals with moderate hearing loss (MHL) (>30 dB) and compared them to age-matched controls with good hearing (GH).We observed that the fractional anisotropy of the right corticospinal tract and left superior longitudinal fasciculus – parietal was higher in subjects with MHL. …”
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92
Psychoradiologic white matter alterations in pediatric Type I bipolar disorder: a diffusion tensor imaging (DTI) study
Published 2025-07-01“…Conclusion Combining FA, MD, and RD parameters provided a comprehensive assessment of microstructural white matter changes in pediatric Type I BD, demonstrating DTI’s potential as a diagnostic tool.…”
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93
Efficacy of Pluchea dioscoridis leaf extract against pathogenic Candida albicans
Published 2017-04-01“…Microscopic observations using scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were made to determine the major alterations in the microstructure of C. albicans. Quantitative changes in phospholipase, hemolysin, and secreted aspartyl proteinase (SAP1 and SAP10) genes expression as virulence factors were analyzed using real-time polymerase chain reaction (RT-PCR). …”
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94
The multimodality neuroimage findings in individuals with Tourette syndrome
Published 2020-10-01“…Therefore, special neuroimaging techniques may be needed to investigate the possible microstructural or functional changes in the brain. Previous structural studies, such as those using diffusion tensor imaging, and volumetric MRI studies, revealed the main abnormalities to be located in the cortico-striatal-thalamo-cortical circuit and to be related to brain regions such as basal ganglion, thalamus, frontal cortex, and motor cortex. …”
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95
Epimedin B protects against bone loss and inflammation in diabetic osteoporosis rats by regulating OPG/RANKL pathway
Published 2025-04-01“…EB promoted the formation of bone trabeculae and altered several bone microstructure parameters in DOP rats. EB ameliorated improved bone structure, restored histological abnormalities of femoral bone, and reduced the number of bone marrow adipocytes in DOP rats. …”
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96
Magnetization transfer MRI of third trimester fetal brain: a pilot of gestational myelin imaging
Published 2025-05-01“…BackgroundMagnetic resonance imaging (MRI) is commonly used as a tool for confirming a fetal brain abnormality suspected on ultrasound. Common clinical MRI sequences typically only reveal changes in the brain once there are gross abnormalities. …”
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97
Impact of glucose metabolism on myocardial fibrosis and inflammation in hypertrophic cardiomyopathy: a cardiac MR study
Published 2025-08-01“…This retrospective study aimed to evaluate myocardial microstructural alterations, particularly fibrosis and subclinical inflammation, in HCM patients across glycemic statuses using multiparametric cardiac magnetic resonance (CMR). …”
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98
Microvascular heterogeneity exploration in core and invasive zones of orthotopic rat glioblastoma via ultrasound localization microscopy
Published 2025-03-01“…ULM demonstrated higher microstructural resolution compared to micro-CT and a nonsignificant difference compared to scanning electron microscopy. …”
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99
Structural and functional changes of Post-Stroke Depression: A multimodal magnetic resonance imaging study
Published 2025-01-01“…This study investigated changes in gray matter volume (GMV), white matter microstructure, and spontaneous brain activity in post-stroke depression (PSD) using multiple MRI techniques, including neurite orientation dispersion and density imaging (NODDI). …”
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100
Altered functional brain connectivity in Dyt1 knock-in mouse models
Published 2025-02-01“…We employed functional magnetic resonance imaging (fMRI) to assess resting-state and sensory-evoked brain connectivity and activation, along with diffusion MRI (dMRI) to evaluate microstructural changes. We hypothesized that dGAG mice would exhibit widespread network disruptions compared to the cortex-specific EMX mice, due to broader TorsinA dysfunction across the basal ganglia and cerebellum. …”
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