Feasibility of GPT-3.5 versus Machine Learning for Automated Surgical Decision-Making Determination: A Multicenter Study on Suspected Appendicitis by Sebastian Sanduleanu, Koray Ersahin, Johannes Bremm, Narmin Talibova, Tim Damer, Merve Erdogan, Jonathan Kottlors, Lukas Goertz, Christiane Bruns, David Maintz, Nuran Abdullayev

“…Developed by OpenAI, the Generative Pre-trained Transformer 3.5 model (GPT-3) may provide enhanced decision support for surgeons in less certain appendicitis cases or those posing a higher risk for (relative) operative contra-indications. …”
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Integrating polygenic risk scores in the prediction of type 2 diabetes risk and subtypes in British Pakistanis and Bangladeshis: A population-based cohort study. by Sam Hodgson, Qin Qin Huang, Neneh Sallah, Genes & Health Research Team, Chris J Griffiths, William G Newman, Richard C Trembath, John Wright, R Thomas Lumbers, Karoline Kuchenbaecker, David A van Heel, Rohini Mathur, Hilary C Martin, Sarah Finer

“…We show that a T2D PRS optimised for this high-risk BPB population has potential clinical application in BPB, improving the identification of T2D risk (especially in the young) on top of an established clinical risk algorithm and aiding identification of subgroups at diagnosis, which may help future efforts to stratify care and treatment of the disease.…”
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Cost-effectiveness of different tuberculosis diagnostic approaches in Nigeria based on decision analytical modelling by Muktar H Aliyu, Hafsat U Ibrahim, Rayyan M Garba, Jameel I Ahmad, Kabiru Abdulsalam, Yasir N Jibril, Faisal S Dankishiya, Abdullahi Ibrahim, Ibrahim U Garzali, Aisha A Galadanci, Abdullahi K Suleiman, Abdulgafar L Olawumi, Umar F Abdullahi, Fatima M Mahmud, Amina A Umar, Olive Asafu- Adjaye, Lukman F Owolabi, Baba M Musa

“…However, the Xpert MTB/RIF Ultra may provide additional value in settings with sufficient infrastructure and funding. …”
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Massive Acquisition of Ultraviolet Color Excess Information from GALEX and UVOT Bands by Dongliang Yang, Mingxu Sun, Biwei Jiang, Wenyuan Cui, Ruoyi Zhang, Luyao Shi, Jiachen Wei

“…This suggests that a single-parameter R _V extinction law may not be sufficient to simultaneously characterize the extinction behavior across infrared, optical, and ultraviolet bands.…”
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Multiomics profiles of genome-wide alterations in H3K27ac in different lung lobes after acute graft-versus-host disease with MSCs treatment by Zixuan Lu, Yuming Zhou, Yuming Zhou, Chengyu Li, A. M. Abd El-Aty, A. M. Abd El-Aty, Chengxia Liu, Xiying Luan, Bin Wang, Guoyan Wang, Guoyan Wang

“…The subset with high expression levels of these genes tended to present anti-inflammatory effects and reduced cytotoxic activity. Our study may provide new insights into the development of potential therapeutic drugs that target H3K27ac to assist in MSC treatment.…”
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Evaluating the expected effects of disclosure of patient safety incidents using hypothetical cases in Korea. by Minsu Ock, Eun Young Choi, Min-Woo Jo, Sang-Il Lee

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Blocking the interaction between S100A9 protein and RAGE V domain using S100A12 protein. by Revansiddha Katte, Chin Yu

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The value of habitat analysis based on 18F-PSMA-1007 PET/CT images for prostate cancer risk grading by Yang Wang, Hongyue Zhao, Zhehao Lyu, Linhan Zhang, Wei Han, Zeyu Wang, Jiafu Wang, Xinyue Zhang, Shibo Guo, Peng Fu, Changjiu Zhao

“…The whole prostate was manually contoured on PET and CT images as the volume of interest (VOI). Using the Otsu algorithm, the VOI was divided into four habitat subregions. …”
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Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma by Di Lian, Chenye Lin, Meiling Xie, JianXing Wei, Xueling Huang, Ke Lian, Qiuyu Tang

“…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses showed that PRDEGs were primarily enriched in biological processes related to the immune response, cell disassembly, and inflammatory pathways.ResultsImmune cell infiltration analysis using the CIBERSORT algorithm revealed significant differences between the CA and control groups, with increased macrophages M0, activated mast cells, and γδ T cells and decreased resting natural killer cells in the CA group. …”
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Assessing tafenoquine implementation in Brazil: a qualitative evaluation of perceptions of healthcare providers and Plasmodium vivax patients (QualiTRuST Study) by Alicia P. C. Santos, Marcelo A. M. Brito, Ana P. S. Oliveira, Rafaela N. Dávila, Hiran S. S. Gama, Evellyn A. R. T. Silva, Hélio A. Amazonas Jr., Patrícia C. S. Balieiro, Rosilene Rufatto, Penny Grewal Daumerie, Cássio R. L. Peterka, Dhélio Batista Pereira, Marcus V. G. Lacerda, Felipe L. G. Murta

“…Positive perceptions of the medication may aid in improving patient adherence to malaria treatment, thereby reducing malaria recurrences. …”
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Allosteric binding sites in Rab11 for potential drug candidates. by Ammu Prasanna Kumar, Suryani Lukman

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The use of informal care by people with vision impairment. by Ana Patricia Marques, Antonio Filipe Macedo, Laura Hernandez-Moreno, Pedro Lima Ramos, Thomas Butt, Gary Rubin, Rui Santana, Portuguese visual impairment study group (PORVIS-group)

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Calcium and cAMP directly modulate the speed of the Drosophila circadian clock. by Angelina Palacios-Muñoz, John Ewer

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Modelling the effect of bednet coverage on malaria transmission in South Sudan. by Abdulaziz Y A Mukhtar, Justin B Munyakazi, Rachid Ouifki, Allan E Clark

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Analysis of factors influencing clinical pregnancy rates in frozen-thawed embryo transfer cycles by Junqiang Wang, Zexing Yang, Ying Chen, Ying Chen, Fengchen Gao, Wenxiu Zhao, Shuxuan Cao, Yixi Li, Limei He, Limei He

“…Baseline characteristics were compared between groups. A random forest algorithm was applied to rank the importance of variables, followed by dimensionality reduction using a sliding window sequential forward selection (SWSFS) method. …”
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The Fetal Region-specific Optimized Growth Standard (FROGS)-A fetal and birthweight centile calculator validated in a national population. by Natasha L Pritchard, Stephen Tong, Teresa MacDonald, Elizabeth McCarthy, Lisa Hui, Michael Bethune, Hannah G Gordon, Roxanne Hastie, Emerson Keenan, Michael Permezel, Susan P Walker, Anthea C Lindquist

“…This study is limited in that it retrospectively assesses birthweight, which may have different implications to a prospective evaluation of estimated fetal weight.…”
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Application of Intravoxel Incoherent Motion in the Prediction of Intra-Tumoral Tertiary Lymphoid Structures in Hepatocellular Carcinoma by Ma L, Liao S, Zhang X, Zhou F, Geng Z, Hu J, Zhang Y, Zhang C, Meng T, Wang S, Xie C

“…The logistic regression algorithm was used to construct the prediction model based on the combination of these features. …”
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Prediction of lung overdistension during mechanical ventilation using micro-RNA and gene expression by Cecilia López-Martínez, Paula Martín-Vicente, Laura Amado-Rodríguez, Inés López-Alonso, Margarita Fernández-Rodríguez, Adrián González-López, Pablo Martínez-Camblor, Juan Gómez, Andrew J. Boyle, Cecilia M. O’Kane, Daniel F. McAuley, James N. Tsoporis, Claudia dos Santos, Guillermo M. Albaiceta

“…Abstract Background Overstretching of lung parenchyma may lead to injury, especially during mechanical ventilation. …”
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Notch signaling and taxis mechanisms regulate early stage angiogenesis: A mathematical and computational model. by Rocío Vega, Manuel Carretero, Rui D M Travasso, Luis L Bonilla

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QTc interval prolongation in critically ill patients: Prevalence, risk factors and associated medications. by Flávia Medeiros Fernandes, Eliane Pereira Silva, Rand Randall Martins, Antonio Gouveia Oliveira

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