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Suggested Topics within your search.
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241
The role of amniotic epithelial cells in preterm birth: mechanisms and clinical implications
Published 2025-08-01Subjects: Get full text
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242
NONSTEROIDAL ANTI-INFLAMMATORY DRUGS: A DIFFICULT CHOICE OF ANESTHESIA DURING JOINT SURGERY
Published 2017-10-01“…NSAIDs have comprehensive analgesic, antiinflammatory, and antipyretic effects associated with blockade of the enzyme cyclooxygenase-2 and suppression of the synthesis of prostaglandins, one of the main mediators of pain and inflammation, which are synthesized in response to surgical tissue injury. …”
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243
Tumor Necrosis Factor-a In Emergency Department Patients with Systemic Inflammation as a Predictor of Severity and Outcome of Sepsis
Published 2008-10-01“…A retrospective observational study was performed on a sample of one hundred adult subjects presenting to the ED with systemic inflammatory response syndrome of 2 etiologies: presumed (and later confirmed in the ICU and/or operating room) severe acute pancreatitis or generalized peritonitis. …”
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244
Effect of isoniazid and its compositions with oxidized dextran on the activity of inflammation and destruction processes in the liver of mice with BCG granulomatosis
Published 2025-07-01“…This suggests that LFD helps modulate the inflammatory response in tissues and reduces damage, likely due to the systemic anti-inflammatory effect of oxidized dextran in the LFD.…”
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245
Phantom tumour: inflammatory pseudotumour of the liver: a rare case report and review of literature
Published 2025-07-01“…Histopathology confirmed a diagnosis of inflammatory pseudotumor with xanthogranulomatous inflammation (Fig 2). …”
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246
Stellate ganglion irradiation alleviates airway inflammation in asthmatic mice via activating SIRT1 signaling pathway
Published 2025-08-01“…Silent information regulator 1 (SIRT1), an NAD+-dependent histone deacetylase, plays a key role in regulating cellular inflammatory responses by inhibiting NF-κB and other inflammatory signaling pathways. …”
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247
Anti-Inflammatory Pathways Modulated by Microbial Polysaccharides from Euganean Thermal Muds in Zebrafish
Published 2025-07-01“…Our findings revealed that M-PS treatment down-regulated the expression of key genes involved in several inflammatory pathways. Gene Set Enrichment Analysis identified eleven up-regulated pathways (e.g., TNF-α signalling via NFκB, IL6–JAK–STAT signalling, p53 pathway, apoptosis, and interferon response) with components reduced in number and expression level in M-PS-treated larvae compared to the inflamed ones. …”
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248
From inflammation to malignancy: ginsenosides as a bridge between traditional healing and modern therapies for periodontitis and oral cancer
Published 2025-08-01“…These saponins possess anti-inflammatory, antioxidant, and anticancer properties, and recent studies indicate they can modulate immune responses, inhibit tumor growth, and lower inflammatory markers in periodontitis by suppressing pro-inflammatory cytokines like IL-6 and TNF-α. …”
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249
Ursolic Acid Regulates Intestinal Microbiota and Inflammatory Cell Infiltration to Prevent Ulcerative Colitis
Published 2021-01-01“…UA could significantly reduce the richness of intestinal flora to avoid the inflammatory response due to the destruction of the intestinal epithelial barrier. …”
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250
Relationship between inflammatory markers and long-term prognosis in ICU patients with acute non-ST-segment elevation myocardial infarction
Published 2025-08-01“…Multivariable Cox proportional hazards model analysis revealed that, in contrast to the low-level group (Q1), higher levels of neutrophil-to-lymphocyte ratio(NLR), neutrophil-to-lymphocyte-platelet ratio (NLPR), red blood cell distribution width (RDW), systemic immune-inflammation index (SII), and systemic inflammation response index (SIRI) were positively associated with ACM within 180 days and 360 days (all P < 0.05). …”
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251
A mouse model of overexpression of human IL-6 by tissue-resident macrophages in the context of LPS-induced inflammation
Published 2024-09-01“…One experimental approach in addressing such models in mice relies on the induction of systemic acute inflammation in response to lipopolysaccharide (LPS) administration. …”
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252
Galcanezumab-induced psoriasis-like lesions of the eyebrows: A case report and review of CGRP's role in cutaneous inflammation
Published 2025-08-01“…However, their systemic side effects, particularly on the skin, where CGRP plays a key role in regulating inflammation and immune responses, are not fully understood. …”
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253
Bioactive Properties of Enzymatically Hydrolyzed Mulberry Leaf Proteins: Antioxidant and Anti-Inflammatory Effects
Published 2025-06-01“…Oxidative stress and inflammatory responses often occur concomitantly, and they are key causative factors in various human and animal diseases. …”
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254
Trends in precision diagnosis and monitoring of inflammatory bowel diseases: the potential of proteomic and metabolomic biomarkers
Published 2025-07-01“…Omics technologies, including proteomics and metabolomics approaches, provide promising opportunities to improve the accuracy of diagnosis and monitoring of the course of inflammatory bowel disease (IBD). Integration of these advanced research areas into clinical medicine not only allows for a more in-depth assessment of the pathogenesis of IBD, but also opens avenues for innovative therapeutic strategies adapted to individual patient profiles and patient cohorts.The lecture analyzes trends in the identification of biomarkers with high sensitivity and specificity that can be used both for diagnosis and prognosis of the course of IBD subtypes, and for predicting the response to therapy, which, ultimately, will contribute not only to improved treatment outcomes, but also to an increase in the quality of life of patients.The authors conducted a non-systematic, descriptive review of the literature with a search depth of 10 years, aimed at systematizing data on the achievements of proteomics and metabolomics approaches for the diagnosis, monitoring of the IBD course, and personalization of therapeutic strategies. …”
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255
Topical steroids as alternative to systemic hormonal treatment for inflammatory bowel diseases in pediatric practice
Published 2011-05-01“…Anti-inflammatory treatment aimed to destruction of «vicious circle» of inflammatory responses occupies the main place in the treatment of IBD. …”
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256
Protective effects of folic acid on ischemia‒reperfusion injury in rat uterus: reduces inflammation damage and apoptotic death
Published 2025-07-01“…Immunohistochemical analysis revealed that caspase-3 activity, a marker of apoptosis, increased in response to IR. However, folic acid treatment attenuated this activity, and uterine inflammation also reduced. …”
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257
Prediction of in-hospital mortality in patients with myocardial infarction and type 2 diabetes: the role of cellular indices of systemic inflammation
Published 2024-08-01“…In the groups of deceased and surviving patients, cellular indices of systemic inflammation were calculated and compared (neutrophil-lymphocyte ratio (NLR), neutrophil-monocyte ratio (NMR), monocyte-lymphocyte ratio (MLR), platelet-lymphocyte ratio (PLR), systemic inflammation index (SII), systemic inflammation response index (SIRI)) and average hsCRP levels). …”
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258
Prostaglandin E𝟐 and the Suppression of Phagocyte Innate Immune Responses in Different Organs
Published 2012-01-01“…Here, we discuss the production of PGE2 and the actions of this prostanoid in phagocytes from different tissues, the relative contribution of PGE2 to the modulation of innate immune responses, and the novel therapeutic opportunities that can be used to control inflammatory responses.…”
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259
Anti-Fibrotic Effect of Tacrolimus on Preventing Adhesion after Achilles Tendon Surgery in a Murine Model
Published 2025-08-01“…Histopathological changes and recruitment of inflammatory cells to the tendon tissue sections were attenuated in the tacrolimus-treated group (P=0.001) in comparison with the positive control group. …”
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260