Serum metabolomics in pulmonary sarcoidosis: metabolic signatures across prognoses by Dafu Zhu, Jianglong Chen, Li Zhang, Hongxu Li, Jingyi Wang, Jiacui Song, Dong Weng, Pengcheng Zhang, Qiuhong Li, Yuan Zhang, Mengmeng Zhao

“…Abstract Background Sarcoidosis is a systemic inflammatory disease, primarily affecting the lungs, with a prognosis that varies widely among patients. …”
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Osteocalcin deficiency attenuates neointima formation after vascular injury in rat by Ming Yi, Yan Li, Jinghao Sun, Jin Si, Huirong Liu, Jing Li

“…Conclusions OCN participates in the pathological processes of vascular neointima formation and promotes inflammatory response of VSMC to vascular injury, but deletion of OCN does not affect vascular integrity under physiological condition, suggesting that OCN may provide new insights into the mechanism of intima hyperplasia.…”
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Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor by Wenpeng Cai, Tao Fan, Chu Xiao, Ziqin Deng, Yixiao Liu, Chunxiang Li, Jie He

“…Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. …”
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Identification of lipid metabolism-related genes in myocardial infarction: implications for diagnosis and therapy by Qiang Wang, Xian Wu, Bo Yu

“…Lipids are critical underlying factors in cardiovascular disease. They influence inflammatory responses and modulate leukocyte, vascular cell and cardiac cell functions, affecting the vasculature and heart. …”
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Clinical-Laboratory Parallels in Patients with Demodectic Blepharitis at Cosmecevtic’s Use by I. B. Medvedev, L. S. Ogmrcjan, G. N. Neshchadim, S. N. Bagrov, N. N. Dergacheva

“…Alongside this, we conducted drug correction of the status of the tear film via artificial tears eyedrops and therapy of blepharitis or blepharoconjunctivitis withantibiotics, steroids or non-steroidal anti-inflammatory drugs. A controlled laboratory testing for the presence of the mite Demodex folliculorum was undertaken after the course of treatment with cream. …”
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Multidisciplinary approach to patients with post-stroke dysphagia to improve swallowing and quality of life by Xu Bu, Rong Xiangxia, Gan Yan, Wei Tao, Zhang Xiufang, Liu Jingjing, Zhang Jing, Wang Zilin

“…Introduction/Objective. Inflammatory bowel disease (IBD) is often diagnosed during patients’ sexually active years, and factors like disease severity, treatment, and surgery may impact sexual function. …”
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Muscle atrophy in polytraumatized patients – a longitudinal observational pilot study by Danjana Teves, Torsten Pastor, Torsten Pastor, Tatjana Pastor, Bergita Ganse, Bergita Ganse, Bergita Ganse

“…In a prospective longitudinal pilot study with 10 patients (Injury Severity Score (ISS) ≥16), hand grip strength and inflammatory blood parameters were assessed. Skeletal muscle thickness of the rectus femoris (RF), vastus lateralis (VL), and tibialis anterior (TA), and subcutaneous tissue thickness over these muscles were measured via ultrasound. …”
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Immunohistochemical study of uveal melanoma and its cellular microenvironment by S. V. Saakyan, L. A. Katargina, E. B. Myakoshina, G. P. Zakharova, I. P. Khoroshilova–Maslova, A. M. Maibogin

“…The immunohistochemical study of CD68+ and CD163+ antigens expressed by anti-inflammatory and pro-tumor macrophages showed that their absolute and relative content in the uveal melanoma tissue is almost the same with a slight predominance of CD163+ (p = 0.7). …”
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Influence of polyamines of bacterial origin on the production of key cytokines in the culture of human mononuclear leukocytes by A. P. Godovalov, T. I. Karpunina

“…In addition, the effects of polyamines upon monocytes present in culture can include their anti-inflammatory state, e.c., an increased IL-4 production. …”
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A novel, synthesized, amphiphilic ethylene glycol squalene derivative suppresses BBN-induced bladder carcinogenesis by Keisuke Sano, Masanobu Shiga, Farhana Ferdousi, Hiromichi Sakurai, Kazuki Hamada, Kozaburo Tanuma, Satoshi Nitta, Yoshiyuki Nagumo, Shuya Kandori, Akio Hoshi, Hiromitsu Negoro, Bryan J. Mathis, Jun Miyazaki, Tran Ngoc Linh, Takashi Arimura, Hiroko Isoda, Hiroyuki Nishiyama

“…Abstract Squalene, a natural triterpene with antioxidant, anti-inflammatory, and immunostimulatory properties, holds promise for cancer therapy. …”
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Optimizing the lithotripsy timing after drainage of the upper urinary tract in patients with urolithiasis and obstructive uropathy by A. I. Khotko, D. N. Khotko, V. M. Popkov, A. I. Tarasenk

“…Subsequently, percutaneous nephrolithotripsy (PNLT) was performed at various times after drainage. The level of inflammatory markers (IL-8) and profibrotic factor (MCP-1) in the urine was determined. …”
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Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth by Thomas Mathivet, Claire Bouleti, Matthias Van Woensel, Fabio Stanchi, Tina Verschuere, Li‐Kun Phng, Joost Dejaegher, Marly Balcer, Ken Matsumoto, Petya B Georgieva, Jochen Belmans, Raf Sciot, Christian Stockmann, Massimiliano Mazzone, Steven De Vleeschouwer, Holger Gerhardt

“…This vascular phenotype transition was accompanied by recruitment of predominantly pro‐inflammatory M1‐like macrophages in the early stages, followed by in situ repolarization to M2‐like macrophages, which produced VEGF‐A and relocate to perivascular areas. …”
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Impact of the COVID-19 Pandemic on Ophthalmic Practice. Historical Aspects and Clinical Examples by V. N. Trubilin, E. G. Poluninа, V. V. Kurenkov, D. V. Andzhelova, E. E. Kazaryan, E. Yu. Markova, K. V. Chinenova, Yu. V. Evstigneeva

“…This phenomenon can be explained by the fact that any inflammatory process occurring on the eye surface disrupts the process of lacrimation and leads to the emergence of dry eye syndrome. …”
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Post hoc analysis of the results of KOLIBRI comparative observational clinical study in patients with knee and small hand joints osteoarthritis by A. Yu. Feklistov, L. D. Vorobieva, O. G. Alekseeva, A. V. Sukhinina, I. A. Andrianova, I. V. Menshikova, V. N. Sorotskaya, E. G. Zotkin

“…In both groups, half of the patients managed to stop further use of non-steroidal anti-inflammatory drugs (NSAIDs) on a regular basis.Conclusion. …”
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Prognostic value and predictive model construction for patients undergoing laparoscopic radical prostatectomy based on the preoperative NPL-IRS score and prognostic nutritional ind... by Hao Wang, Pu-shen Yang, Yi-rui Wei, Da-wei Xie, Si-qi Wang, Wei-feng He, Wei Wang, Jian-wen Wang

“…The NPL-IRS score was inflammatory response system score based on the cut-off values NLR, PLR, LMR. …”
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Neuroprotective effect of Tozasertib in Streptozotocin-induced alzheimer’s mice model by Darshpreet Kaur, Amarjot Kaur Grewal, Suad Hamdan Almasoudi, Ahmad H Almehmadi, Bshra A. Alsfouk, Amit Kumar, Varinder Singh, Athanasios Alexiou, Marios Papadakis, Nermeen N. Welson, Thakur Gurjeet Singh, Gaber El-Saber Batiha

“…The results showed that administration of tozasertib improved memory, decreased levels of oxidative stress, inflammatory parameters, and apoptotic markers, and improved histological parameters in a dose-dependent manner. …”
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Modern possibilities of therapy of nonspecific pain in the lower back by D. H. Khaibullina, Yu. N. Maksimov

“…Some patients with severe pain continued to receive previously prescribed non-steroidal anti-inflammatory drugs (NSAIDs). After completing the course of treatment with Ambene® Bio, the overall effect of the therapy, changes in individual need for NSAIDs and the presence of adverse events were assessed.Results. …”
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Long-term multicenter observational study of the drug Alflutop in Russia: use in patients with knee osteoarthritis (report 4) by E. A. Taskina, L. I. Alekseeva, N. G. Kashevarova, A. M. Lila

“…The efficacy of the treatment was assessed by the dynamics of pain intensity using a visual analogue scale (VAS), patient's general health assessment (PHA) using VAS and quality of life using EQ-5D, and the need for non-steroidal anti-inflammatory drugs (NSAIDs). Results and discussion. …”
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Metastases of squamous cell carcinoma in the lymph nodes of the neck without the revealed primary focus by I. G. Komarov, D. A. Karseladze, A. I. Senderovich, A. I. Karseladze, K. V. Smirnova, M. A. Кrylovetskaya

“…To establish the localization of the primary focus, traditional diagnostic procedures are not always effective: in morphological analysis, the primary focus can be hidden behind inflammatory changes, in addition, the tumor lesion can be of a primary focus. …”
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Evaluation of safety and efficacy of Tirofiban injection for treating acute ischemic stroke beyond standard time window by Qian Yang, Qiaofeng He, Xinfa Mao, Weibing Fan, Xin Luo

“…No significant differences were observed between the two groups in inflammatory markers (hs-CRP and IL-6), intracranial hemorrhage, or mortality. …”
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