Noradrenaline for progressive supranuclear palsy syndromes (NORAPS): a randomised, double-blind, placebo-controlled, crossover Phase IIb clinical trial evaluating the efficacy and... by Robert Durcan, Christopher Kobylecki, Lee Shepstone, James B Rowe, Alistair Church, Duncan Street, Vicky Marshall, Charlotte Russell, Luca Passamonti, Juliet High, Christopher T Rodgers, Boyd C P Ghosh, Kelly Grant, Natalia Igosheva, Hugo Paula, Colin McAlister, Simon P Jones, Rong Ye, Chrystalina Antoniades

“…Apathy and impulsivity are very common, often coexistent in PSP, and negatively predict survival. In preclinical models and other diseases, apathy and impulsivity are associated with noradrenergic deficits, which can be severe in PSP.Methods and analysis Noradrenaline for Progressive Supranuclear Palsy Syndromes trial is a randomised, double-blind, placebo-controlled, crossover design, Phase IIb clinical trial to evaluate the efficacy and safety of oral atomoxetine for the treatment of cognitive and behavioural changes in PSP. …”
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Cervical cancer cell–derived angiopoietins promote tumor progression by Ping Yang, Na Chen, Dongyun Yang, Janet Crane, Bangxing Huang, Ruiqing Dong, Xiaoqing Yi, Jing Guo, Jing Cai, Zehua Wang

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DeepExtremeCubes: Earth system spatio-temporal data for assessing compound heatwave and drought impacts by Chaonan Ji, Tonio Fincke, Vitus Benson, Gustau Camps-Valls, Miguel-Ángel Fernández-Torres, Fabian Gans, Guido Kraemer, Francesco Martinuzzi, David Montero, Karin Mora, Oscar J. Pellicer-Valero, Claire Robin, Maximilian Söchting, Mélanie Weynants, Miguel D. Mahecha

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Uncovering Hippo pathway-related biomarkers in acute myocardial infarction via scRNA-seq binding transcriptomics by Xingda Li, Xueqi He, Yu Zhang, Xinyuan Hao, Anqi Xiong, Jiayu Huang, Biying Jiang, Zaiyu Tong, Haiyan Huang, Lian Yi, Wenjia Chen

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The platelet to high-density lipoprotein cholesterol ratio is associated with thyroid hormone abnormalities based on NHANES 2007 to 2012 data by Wu Li, Peng Wu

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Mass Spectrometric Based Metabolomics of the Saudi Cultivar of Fenugreek (<i>Trigonella foenum-graecum</i> L.): A Combined GC-MS, Antimicrobial and Computational Approach by Nujud A. M. Almuzaini, Abdel Moneim E. Sulieman, Naimah A. Alanazi, Riadh Badraoui, Emad M. Abdallah

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Genetic Insights Into Craniosynostosis: Identification of Novel IL11RA Variants in Chinese Pediatric Patients by Ziwei Liu, Ding Zhou, Chunli Wang, Bixia Zheng, Qing Yan, Wei Zhou, Gang Wang

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Research Progress in Artificial Intelligence for Central Serous Chorioretinopathy: A Systematic Review by Ping Zhang, Qing Zhang, Xinya Hu, Wei Chi, Weihua Yang

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The impact of artificial intelligence on medical diagnostics: A letter to the editor by Sahar Imtiaz, Sheikh Abdul Qadir Jillani

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Influence of weekly physical exercises on indicators of biological age of student's youth by Stanislav Prysiazhniuk, Oleksandr Pryimakov, Sergii Iermakov, Dmytro Oleniev, Jerzy Eider, Natalija Mazurok

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Examining Individuals’ Use of the Internet for Health Care Activities Over Time: Results from the US National Health Interview Survey by Zachary Junkins, Nusrath Zahan, David Neyens

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Decoding Global Palates: Unveiling Cross-Cultural Flavor Preferences Through Online Recipes by Qing Zhang, David Elsweiler, Christoph Trattner

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Biomechanical Analysis of Different Pacifiers and Their Effects on the Upper Jaw and Tongue by Luca Levrini, Luigi Paracchini, Luigia Ricci, Maria Sparaco, Stefano Saran, Giulia Mulè

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Adherence to COVID-19 policy measures: Behavioral insights from The Netherlands and Belgium. by Eline van den Broek-Altenburg, Adam Atherly

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Systemic inflammation markers (SII and SIRI) as predictors of cognitive performance: evidence from NHANES 2011–2014 by Xiaoyue Wang, Qinghua Wen, Yujie Li, Huanhuan Zhu, Fengyin Zhang, Simin Li, Lin Zhan, Lin Zhan, Juan Li

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Correlation between the body roundness index and chronic obstructive pulmonary disease: a cross-sectional analysis by Longqian Li, Mingzhi Lin, ZhuoLin Qin, Yan Liu, Xiangji Dang, Cheng Wang

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Multiclass leukemia cell classification using hybrid deep learning and machine learning with CNN-based feature extraction by Sazzli Kasim, Sorayya Malek, JunJie Tang, Xue Ning Kiew, Song Cheen, Bryan Liew, Norashikin Saidon, Raja Ezman, Raja Shariff

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Tuberculosis Trends in the Post‐COVID‐19 Era: Is It Going to be a Global Concern? by Soroush Khojasteh‐Kaffash, Adrina Habibzadeh, Sina Moghaddam, Fatemeh Afra, Noosha Samieefar, Abolfazl Fateh

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Relationship between albumin-corrected anion gap and non-alcoholic fatty liver disease: a cross-sectional analysis of NHANES 2017–2018 by Ning Bai, Ting Ying, Dejian Li, Aiguo Liu, Aiguo Liu

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A Survey of Machine Learning in Edge Computing: Techniques, Frameworks, Applications, Issues, and Research Directions by Oumayma Jouini, Kaouthar Sethom, Abdallah Namoun, Nasser Aljohani, Meshari Huwaytim Alanazi, Mohammad N. Alanazi

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