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    Development and recalibration of a multivariable type 1 diabetes prediction model for type 1 diabetes across multiple screening studies by Erin L. Templeman, Lauric A. Ferrat, Hemang M. Parikh, Lu You, Taylor M. Triolo, Andrea K. Steck, William A. Hagopian, Kendra Vehik, Suna Onengut-Gumuscu, Peter A. Gottlieb, Stephen S. Rich, Jeffery P. Krischer, Maria J. Redondo, Richard A. Oram, the Type 1 diabetes TrialNet Study Group

    Published 2025-07-01
    “…A web calculator was developed to visualise individual risk estimates ( https://t1dpredictor.diabetesgenes.org ). Conclusions A stratified model incorporating the type 1 diabetes genetic risk score, family history, age, and autoantibody status can predict type 1 diabetes risk with improved accuracy, but may need recalibration depending on the screening strategy.…”
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    HERGAI: an artificial intelligence tool for structure-based prediction of hERG inhibitors by Viet-Khoa Tran-Nguyen, Ulrick Fineddie Randriharimanamizara, Olivier Taboureau

    Published 2025-07-01
    “…It also demonstrated superior screening power compared to virtual screening schemes that used existing scoring functions. This model, named “HERGAI,” along with relevant input/output data and user-friendly source code, is available in our GitHub repository ( https://github.com/vktrannguyen/HERGAI ) and can be used to predict drug-induced hERG blockade, even on large data sets.…”
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