Optimizing oral 3-hydroxybutyrate dosage using pharmacokinetic model to improve cognitive function and mood in healthy subjects by Kentaro Nishioka, Kentaro Nishioka, Kentaro Nishioka, Takahiro Ishimoto, Mariko Sato, Ruki Yasuda, Yumi Nakamura, Hiroshi Watanabe, Toshihide Suzuki, Yudai Araragi, Yukio Kato, Ken-ichi Yoshida, Norihito Murayama

“…In the efficacy study, a randomized, double-blinded, and placebo-controlled crossover trial, the effects of 3-HB at the predicted doses on cognitive function and mood in healthy subjects were assessed by a serial arithmetic test (SAT), the cognitrax, the profile of mood states 2nd edition (POMS2), and fatigue visual analog scale (VAS).ResultsIn the pharmacokinetic study, a one-compartment model that includes saturable and non-saturable absorption pathways, constant biosynthesis, and the linear elimination of 3-HB after oral administration were constructed. …”
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Newly Isolated Priestia megaterium LAMA1607 for Enhanced Biological Phosphorus Removal: A Genomic and Functional Characterization by Maria Eduarda Castro do Nascimento, Letícia Coelho Montagna, Laíza Manfroi, Yan de Oliveira Laaf, Luigi Ferrazza Maiochi, Marcus Adonai Castro da Silva, André Oliveira de Souza Lima

“…Meanwhile, tests on the effluent demonstrated significant phosphorus removal. …”
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Kidney function is associated with plasma ATN biomarkers among Hispanics/Latinos: SOL-INCA and HCHS/SOL results by Natasha Z. Anita, Wassim Tarraf, Sayaka Kuwayama, Freddie Márquez, Charles DeCarli, Bharat Thyagarajan, Nora Franceschini, James P. Lash, Tanya Johns, Kevin A. González, Martha Daviglus, Haibo Zhou, Ariana M. Stickel, Frank J. Penedo, Tatjana Rundek, Doug Galasko, Hector M. González

“…Abstract Background Plasma amyloid-tau-neurodegeneration (ATN) biomarker levels may be influenced by non-brain systems, such as kidney function, which could impact the interpretation of ATN biomarker results, particularly in groups like Hispanic/Latino individuals with higher rates of cardiometabolic health issues. …”
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Markers of placental function correlate with prevalence and quantity of nucleated fetal cells in maternal circulation in normotensive term pregnancies by Heidi E. Fjeldstad, Daniel P. Jacobsen, Guro M. Johnsen, Meryam Sugulle, Angel Chae, Sami B. Kanaan, Hilary S. Gammill, Anne Cathrine Staff

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Pragmatic questionnaire-based evaluation of auditory function in individuals with major neurocognitive disorders and hearing loss in diverse contexts by Panagiotis Alexopoulos, Panagiotis Alexopoulos, Panagiotis Alexopoulos, Panagiotis Alexopoulos, Antonios Alexandros Demertzis, Panagiotis Biris, Polychronis Economou, Eric Frison, Piers Dawes, Iracema Leroi

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Monitoring of the Effectiveness of Intensive Care and Rehabilitation by Evaluating the Functional Activity of the Autonomic Nervous System in Patients with Brain Damage by Yu. Yu. Kiryachkov, A. V. Grechko, D. L. Kolesov, A. A. Loginov, M. V. Petrova, M. Rubanes, I. V. Pryanikov

“…Purpose: evaluation of the clinical significance of parametric monitoring of the effectiveness of intensive care and rehabilitation based on the analysis of the functional state of the autonomous nervous system in patients with brain damage of different genesis.Materials and methods. …”
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Effects of maternal blood beta-hydroxybutyrate on brown adipose tissue functions and thermogenic and metabolic health in neonatal calves by Yang Gai, Guiling Ma, Shuyan Yang, Zhiyong Hu, Yulin Ma, Rui He, Yu Zhang, Shilong Huang, Hossam H. Azzaz, Zhaobing Gu, Shengyong Mao, Morteza H. Ghaffari, Yanting Chen

“…ABSTRACT: Maternal metabolic health, particularly during late pregnancy, plays a crucial role in fetal development and postnatal metabolic function. Elevated levels of BHB in dry cows, commonly observed in late gestation, may affect offspring development, but the effects on brown adipose tissue (BAT) and metabolic health remain unclear. …”
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Function of B8N6S4 in Regulating the Growth and Aflatoxin B1 Biosynthesis of Aspergillus flavus by Xinze ZHANG, Ruisi PU, Jinlu NIU, Wenjie HUANG, Shijuan YAN, Wenyang ZHANG, Shaowen WU

“…【Objective】The objective of this study is to examine the function of Zn(Ⅱ)2Cys6 transcription factor B8N6S4 in Aspergillus flavus, and to analyze the role of B8N6S4 in the growth, development, and Aflatoxin B1 (AFB1) biosynthesis of A. flavus.…”
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Estimating the Parameters of Exponential-Rayleigh Distribution under Type-I Censored Data by Rihaam N Shatti, Iden H. Al-Kinani

“…And the number of patients who survived during the study period was (n-m=697), then utilized one of the most important non-parametric tests which is the Chi-square test to determine if the sample (data) corresponded with the Exponential-Rayleigh distribution (ER). then, after estimating the parameters of ER distribution for singly type-I censoring data, compute the survival function, hazard function, and probability density function. …”
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White Matter Microstructure Alterations in Older Adults With Dyslipidemia Associated With Cognitive and Locomotor Dysfunction Evaluated Using Neurite Orientation Dispersion and Den... by Zaimire Mahemuti, Christina Andica, Koji Kamagata, Kaito Takabayashi, Wataru Uchida, Sen Guo, Takashi Arai, Hiroki Tabata, Hitoshi Naito, Yoshifumi Tamura, Ryuzo Kawamori, Hirotaka Watada, Shigeki Aoki

“…Particularly, NODDI indicates a lower intra‐axonal volume, which may suggest axonal loss associated with dyslipidemia, and correlates with cognitive and locomotor function decline.…”
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Exercise‐Induced Cardiac Troponin I Elevation Is Associated With Regional Alterations in Left Ventricular Strain in High‐Troponin Responders by Christine Bjørkvik Erevik, Øyunn Kleiven, Vidar Frøysa, Magnus Bjørkavoll‐Bergseth, Monica Chivulescu, Lars Gunnar Klæboe, Lars Dejgaard, Bjørn Auestad, Øyvind Skadberg, Tor Melberg, Stig Urheim, Kristina Haugaa, Thor Edvardsen, Stein Ørn

“…This study aimed to determine if individuals with a high exercise‐induced cardiac troponin I (cTnI) response have alterations in myocardial function following high‐intensity endurance exercise compared with normal‐cTnI responders. …”
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Assessment of garden cress (Lepidium sativum) seeds supplementation on Gilthead seabream (Sparus aurata) growth, general health, immunity, histopathology, and heat stress tolerance by Mohamed M. Toutou, Mohamed M. Hebalah, Manal I. El-Barbary, Ehab El-Haroun, Norhan E. Saleh

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Relative hand grip strength and functional fitness among older adults with type II diabetes in Egypt: A cross-sectional study by Mohammed Youssef Elhamrawy, Ali Mohammed Hassan, Jobby George, Sami Ahmed Zaher Basha, Mohammed Ali Mohammed Sarhan, Zeinab M Abdelrehim, Mohamed T. Said, Saher Lotfy Elgayar

“…Participants were assessed for relative handgrip strength (rHGS) using a hand dynamometer, and for functional fitness using the Timed Up and Go test (TUG), the 30-second chair stand, and the 2-minute walk test (2-MWT), all during the same visit. …”
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DIFFERENCES OF PEAK EXPIRATION FLOW RATE (PEFR) BETWEEN BRISK WALKING AND HIGH INTENSITY INTERVAL TRAINING (HIIT) IN YOUNG ADULTS by Vania Nazhara Fitriana, Yosef Purwoko, Sumardi Widodo, Tanjung Ayu Sumekar

“…The aim of this research is to determine the difference of PEFR between HIIT and brisk walking, that could depict lung function. Method : This research used quasi experimental with pre-test and post-test comparison group design. …”
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A machine learning model for automated contact tracing during disease outbreaks by Zeyad Aklah, Amean Al-Safi, Marwa H. Abdali, Khalid Al-jabery

“…The model employs logistic functions to quantify the influence of each parameter on the overall ROI. …”
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Effect of a Four-week Core Stability Training Program on the Kinetic Parameters in Athletes With Functional Ankle Instability During Single-leg Drop Landing by Narges Pirmohammadi, Elham Shirzad, Hooman Minounejad

“…Introduction: This study aimed to investigate the effect of a 4-week core stability training program on landing kinetic parameters in athletes with functional ankle instability during a single-leg drop landing exercise. …”
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The effect of warm saltwater and warm water baths on pain, fatigue, sleep quality, and functional capacity in patients with rheumatoid arthritis: a randomized controlled study✰ by Okşan Aktaş, Ayşe Arikan Dönmez, Sevgisun Kapucu, Muhammet Çinar

“…Abstract Background Pain, fatigue, poor sleep quality and functional capacity are the most common symptoms in patients with rheumatoid arthritis. …”
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Effect of combined bioprocessing on antioxidant activity, chemical, functional, and microstructural properties of malted and fermented pearl millet (Pennisetum glaucum) and sorghum... by Gbeminiyi Olamiti, Thakhani Kennedy Takalani, Daniso Beswa, Afam Israel Obiefuna Jideani

“…The study investigated the impact of malting and fermentation durations on the antioxidant activity, chemical, functional, and microstructural attributes of pearl millet cultivars (Agrigreen and Babala) and sorghum flour. …”
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Hepatitis D virus antibodies and liver function profile among patients with chronic hepatitis B infection in Abuja, Nigeria by Lukman O Abdulkareem, Dennis A Ndububa, Augustine O Uhunmwangho, Thahir Yunusa

“…This study aimed at determining the prevalence rate of HDV antibodies among individuals with chronic hepatitis B (CHB) infection and comparing the liver function test (LFT) and disease severity among the anti-HDV positive (anti-HDV+) and anti-HDV negative (anti-HDV-) individuals. …”
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Selection of the Best Copula Function in Bivariate Analysis of Water Resources Components (Case study: Siminehrood River Basin, Iran) by Fahimeh Sharifan, Yousef Ramezani, Mahdi Amirabadizadeh, Carlo De Michele

“…Using the Kolmogorov-Smirnov and Anderson-Darling tests, statistical distribution functions for precipitation, river discharge, river salinity and groundwater level were obtained Lognormal, Gamma, Burr and Lognormal distributions, respectively. …”
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