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3541
Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models
Published 2017-01-01“…Further, surgical placement of stem cell-derived grafts (RPE, retinal progenitors, and photoreceptor precursors) into the vitreous cavity or subretinal space has been well established. For preclinical tests, assessments of stem cell-derived graft survival and functionality are conducted in animal models by various noninvasive approaches and imaging modalities. …”
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3542
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3543
Structural and Functional Disorders in Glaucoma: Prospects for Preclinical Diagnosis. Part 2. Electrophysiological Markers of Early Neuroplastic Events
Published 2020-11-01“…Analysis of the literature on the problem of structural and functional relationships in the development and progression of glaucomatous optical neuropathy (GON) shows that the search for a single primary factor may lead to an erroneous exaggeration of its role in the pathogenesis of GON. …”
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3544
Antidiabetic, antioxidant, and therapeutic effects of Salvia balansae leaf and stem extracts on sexual function in diabetic male rats
Published 2025-01-01“…This work demonstrates the therapeutic potential of S. balansae leaf and stem extracts in improving reproductive function in diabetic rats, potentially through its antioxidant, antihyperglycemic and aphrodisiac properties.…”
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3545
CLINICAL AND FUNCTIONAL CHARACTERISTICS OF PATIENTS AFTER Q-WAVE MYOCARDIAL INFARCTION DEPENDING ON THE METABOLIC SYNDROME PRESENCE OR ABSENCE
Published 2015-09-01“…To study the clinical and functional parameters of patients after acute Q-wave myocardial infarction (Q-MI) depending on the concomitant metabolic syndrome (MS). …”
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3546
Development of a Measure of Family Functioning for Hispanic Sexual Minority Adolescents: A Study Protocol for Measure Development
Published 2025-03-01“…Currently, there are no empirically tested measures of family-functioning specifically developed for HSMY. …”
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3547
Influence of combined therapy with prospidin and methotrexate on radiological progression, functional status and quality of life in pts with rheumatoid arthritis
Published 2004-06-01“…To evaluate influence of combination therapy with prospidin (P) and methotrexate (MTX) on X-ray progression, functional status (FS) and quality of life (QL) in patients with rheumatoid arthritis (RA) in comparison with MTX monotherapy. …”
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3548
Exploring undue advantage of differential item functioning in high-stakes assessments: Implications on sustainable development goal 4
Published 2025-01-01“…In ensuring equity of measurement between subgroups at the item level, Differential Item Functioning (DIF) analysis is essential. However, discounting DIF affects validity, thereby making Sustainable Development goal 4 (SDG4) challenging to attain. …”
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3549
Transient expression of goose IFN-α gene in COS-7 cells and primary investigation of its antiviral function
Published 2011-07-01“…To elucidate the character and functions of goose interferon-alpha gene (IFN-α), the gene IFN-α of Tianfu meat goose open reading frame (ORF) was cloned into eukaryotic expression vector pcDNA3.1 (+) to generate the recombinant plasmid pcDNA3.1-goIFN-α, which was then transfected into the COS-7 cells by lipofectin transfection. …”
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3550
Changes in the health status and functional outcomes in acute traumatic hand injury patients, during physical therapy treatment
Published 2011-01-01“…Statistical Analysis Used: A One-way ANOVA test. Results: At end of 6 months, among eight subscales of SF-36, there is improvement in mean scores of physical functioning (39.1%). …”
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3551
Setting Reaction of Dental Resin-Modified Glass Ionomer Restoratives as a Function of Curing Depth and Postirradiation Time
Published 2015-01-01“…The results showed that the depth of cure increased over time by the continuous acid-base reaction rather than photopolymerization or chemical polymerization. Microhardness tests seemed less suitable for studying the setting reaction as a function of postirradiation time, probably due to softening from the humidity. …”
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3552
A Riemannian framework for incorporating white matter bundle prior in orientation distribution function based tractography algorithms.
Published 2025-01-01“…Moreover, the fiber reconstruction may be improved on clinical data, informed by prior extracted on high quality data, and therefore could help in the study of brain anatomy and function.…”
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3553
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3554
Effect of rituximab on the manifestations of activity and pulmonary function in patients with systemic sclerosis: one-year follow-up evaluation
Published 2019-07-01“…We were the first to show the association of positive changes in the measures of pulmonary function tests with the dose of RTM.…”
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3555
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3556
Plantar Pressure Distribution among Older Persons with Different Types of Foot and Its Correlation with Functional Reach Distance
Published 2016-01-01“…The plantar pressure (maxP) and contact area were analyzed using Footscan® RSScan platform. The Kruskal-Wallis test was used to compare the plantar pressure between foot types and Spearman’s correlation coefficient was used to correlate plantar pressure with the functional reach distance. …”
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3557
The flexibility of SABRE, a new quantitative receptor function model, when fitting challenging concentration-effect data
Published 2025-06-01“…The Signal Amplification, Binding affinity, and Receptor-activation Efficacy (SABRE) model is the most recent general and quantitative model of receptor function, which enables the determination of Kd (the equilibrium dissociation constant of the agonist-receptor complex) and q (the fraction of the operable receptors after a partial irreversible receptor inactivation) from purely functional data. …”
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3558
Variation in leaf functional trait and ecological strategies in two seedling species in disturbed forest fragments in Eastern Amazonia
Published 2025-05-01“…We tested whether the functional traits and ecological strategies of the species Bactris hirta Mart. and Tetracera sp. in the seedling stage respond to water and soil nutrient availability and landscape variation. …”
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3559
Effectiveness of a training program for caregivers of institutionalized older people on sedentary behavior, physical activity, and functionality of residents
Published 2024-10-01“…Primary outcomes: Sedentary behavior (accelerometry) and functional mobility (Timed Up and Go). Secondary: physical function (SPPB), the performance of activities of daily living (Barthel Index), physical activity (accelerometer), handgrip strength, and anthropometric measurements. …”
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3560
Evaluation of silicon nitride as a substrate for culture of PC12 cells: an interfacial model for functional studies in neurons.
Published 2014-01-01“…Therefore, our study of the interaction of the silicon nitride surface with PC12 cells provides important information for the production of devices that need to have optimal cell culture-supporting properties in order to be used in the study of neuronal functions.…”
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