The Effect of Nicotinamide Mononucleotide and Riboside on Skeletal Muscle Mass and Function: A Systematic Review and Meta‐Analysis by Konstantinos Prokopidis, Frank Moriarty, Gülistan Bahat, Joseph McLean, David D. Church, Harnish P. Patel

“…ABSTRACT Introduction Sarcopenia is associated with the loss of skeletal muscle function and mass. Nicotinamide precursors, such as nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR), have received attention for their potential to improve NAD+ levels and mitigate age‐related sarcopenia in preliminary models, though evidence on their effects in older adults remains inconclusive. …”
Get full text

Intrinsic capacity, functional and psychosocial aspects of older adults participating in a multicomponent physical exercise program by Sarah Giulia Bandeira Felipe, Clarisse Bielh Printes, Fabiane de Oliveira Brauner, Douglas Katusohi Sato, Rafael Reimann Baptista, Rafael Reimann Baptista

“…This study aimed to evaluate the effects of such a program on IC, functional, and psychosocial aspects in older adults.MethodsThis pre- and post-study assessed older adults in Brazil enrolled in a multicomponent training program, evaluating IC as the main outcome using specific tests for each domain. …”
Get full text

Utilisation of Rosehip Waste Powder as a Functional Ingredient to Enrich Waffle Cones with Fibres, Polyphenols, and Carotenoids by Alexandra Raluca Borşa (Bogdan), Adriana Păucean, Melinda Fogarasi, Floricuța Ranga, Andrei Borșa, Anda Elena Tanislav, Vlad Mureșan, Cristina Anamaria Semeniuc

“…The solid waste generated from processing rosehip fruits into jam is valuable due to its rich content in fibres, polyphenols, and carotenoids; it could be valorised as a functional ingredient in a powder form to enrich food products. …”
Get full text

The nasal mycobiome of individuals with allergic rhinitis and asthma differs from that of healthy controls in composition, structure and function by Marcos Pérez-Losada, Marcos Pérez-Losada, Eduardo Castro-Nallar, Eduardo Castro-Nallar, Jenaro García-Huidobro, José Laerte Boechat, José Laerte Boechat, Luis Delgado, Luis Delgado, Luis Delgado, Tiago Azenha Rama, Tiago Azenha Rama, Manuela Oliveira, Manuela Oliveira

Get full text

A Two-Way Mendelian Randomization Analysis on the Link between Thyroid Activity Function and Coronary Atherosclerosis by Le-tai Li, Jia-jie Leng, Yu-xiang Luo, Rong-jia Liu, Zhuo-xuan Song, Meng Ye, Zhen-han Li, Zhen-rui Cao, Ying-jiu Jiang, Hong-tao Tie

“…Coronary atherosclerosis is not related to increased risk of five thyroid function phenotypes in reverse MR analysis. The sensitivity analysis provided relatively reliable evidence to reinforce the validity of our findings. …”
Get full text

Prediction of antipsychotic drug efficacy for schizophrenia treatment based on neural features of the resting-state functional connectome by Song Liu, Meng Wang, Weiyi Han, Anran Chen, Xuzhen Liu, Kang Liu, Xue Li, Yi Chen, Luwen Zhang, Qing Liu, Xiaoge Guo, Xiujuan Wang, Ning Kang, Yong Han, Yuanbo Li, Xi Su, Luxian Lv, Bing Liu, Wenqiang Li, Yongfeng Yang

“…These functional features can be used to predict the PANSS total score reduction rate of SZ patients through a model. …”
Get full text

Salivary mycobiome alterations in HIV-infected MSM: dominance of Pseudogymnoascus and functional shifts across disease stages by Ying Guo, Ying Guo, Lu Lin, Miao Zhang, Yixi Yu, Yan Wang, Jie Cao, Yuchen Li, Xintong Sun, Meilin Guan, Shuo Wen, Xin Wang, Zhen Fang, Wenshan Duan, Junyi Duan, Tao Huang, Wei Xia, Shan Guo, Feili Wei, Dongxiang Zheng, Xiaojie Huang

“…Functional analysis revealed 113 shared KEGG pathways, of which 69 were unique to Stage 3, primarily related to metabolic and disease-related processes. …”
Get full text

Study on the Relationship between Swallowing-Related Muscle Activity and Respiratory Muscle Function in Stroke Patients with Dysphagia by SU Panpan, HE Chuan, FENG Min, JIA Yuanyuan, WANG Tiantian, MENG Dianhuai

“…Maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) of all subjects were assessed using a pulmonary function tester. The 40 stroke patients were divided into non-respiratory muscle weakness group (MIP≥70% and/or MEP≥70% of predicted values) of 15 patients and respiratory muscle weakness group (MIP<70% and MEP<70% of predicted values) of 25 patients based on the results of MEP and MIP tests. sEMG was used to collect the signals from the submental muscles and infrahyoid muscles on both the healthy and affected sides of all subjects while swallowing 5 mL of water. …”
Get full text

Functional Outcome of Epidural Steroid Injection in the Treatment of Chronic Low Backache due to Intervertebral Disc Prolapse by R Sahaya Jose, SL Binesh, N Kattu Bava, M Syed Moosa

“…Version 20.0 of SPSS was employed for the analysis. The Chi-squared test will be used to determine the statistical significance of the relationship between the functional outcome of an ESI and qualitative indicators. …”
Get full text

Innovative machine learning-based prediction of early airway hyperresponsiveness using baseline pulmonary function parameters by Hua Yang, Xingru Zhao, Zhuochang Chen, Lihong Yang, Guihua Zhao, Chenxiao Xu, Jinyi Xu

“…This study explores the potential of baseline pulmonary function parameters, particularly small airway indices, in predicting AHR and develops a machine learning-based model to improve screening efficiency and reduce unnecessary BPT referrals.MethodsThis retrospective study analyzed baseline pulmonary function data and BPT results from Henan Provincial People’s Hospital (May to September 2024). …”
Get full text

Relationships between blood pressure indicators and fluid biomarkers of brain aging in functionally intact older adults by Anna M. VandeBunte, Bailey L. Ortiz, Emily W. Paolillo, Rowan Saloner, Valentina Diaz, Shubir Dutt, Claire J. Cadwallader, Coty Chen, Argentina Lario Lago, Julio C. Rojas, Brandon Chan, Isabel Sible, Joel H. Kramer, Kaitlin B. Casaletto

“…Separate regression models evaluated plasma biomarkers as a function of each blood pressure metric, adjusting for age and biological sex. …”
Get full text

Interactions between gut microbiota, plasma metabolome and brain function in the setting of a HIV cure trial by Alessandra Borgognone, Anna Prats, Anna Prats, Ashish Arunkumar Sharma, Ignacio Martinez-Zalacaín, Ignacio Martinez-Zalacaín, Carles Soriano-Mas, Carles Soriano-Mas, Carles Soriano-Mas, Christian Brander, Christian Brander, Christian Brander, Christian Brander, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, José Moltó, José Moltó, José Moltó, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Rafick-Pierre Sekaly, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Jose A. Muñoz-Moreno, Jose A. Muñoz-Moreno, Jose A. Muñoz-Moreno

“…Here, we analyzed longitudinal gut microbiome, plasma metabolome and brain functioning data to identify potential associations and novel putative biomarkers of HIV-associated neurocognitive disorders (HAND).MethodsData from fecal shotgun metagenomics, plasma metabolome, cognitive (standardized neuropsychological test score covering 6 cognitive domains, NPZ-6), functional (neuropsychiatric symptoms) and neuroimaging assessments were obtained and evaluated in 18 participants before and after RMD administration, and at the study end (post-MAP follow-up) in the BCN02 trial.ResultsParticipants with neurocognitive impairment (Lower vs. …”
Get full text

Functionalized Boron Carbide Nanoparticles as Active Boron Delivery Agents Dedicated to Boron Neutron Capture Therapy by Rudawska A, Szermer-Olearnik B, Szczygieł A, Mierzejewska J, Węgierek-Ciura K, Żeliszewska P, Kozień D, Chaszczewska-Markowska M, Adamczyk Z, Rusiniak P, Wątor K, Rapak A, Pędzich Z, Pajtasz-Piasecka E

“…Therefore, we propose the use of boron carbide (B4C) nanoparticles functionalized with antibodies directed against receptors overexpressed in cancer cells, such as the low-density lipoprotein receptor (LDLR) and the epidermal growth factor receptor (EGFR).Methods: Hydrodynamic diameter measurements confirmed the stability of functionalized B4C nanoparticles in culture media during biological tests lasting up to 72 hours. …”
Get full text

Comparative effect of ARNI and ACEI/ARB on left ventricular diastolic function in patients with hypertensive heart disease by YANG Hao, HE Yi, WANG Fangjuan

“…Objective‍　‍To investigate whether there exist differences in the improvement of left ventricular diastolic function between angiotensin receptor-neprilysin inhibitor (ARNI) and angiotensin-converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB) in patients with hypertensive heart disease (HHD). …”
Get full text

Bone mineral density in comparison to anthropometric parameters and level of gross motor function in children with cerebral palsy by Zvekić-Svorcan Jelena, Stojšić Mirjana, Krasnik Rastislava, Nenadov Nataša, Demeši-Drljan Čila, Mikov Aleksandra, Radovanov Maja

“…The aim of this work was to estimate bone mineral density in relation to the anthropometric parameters and the level of gross motor function in the children with cerebral palsy. Methods. …”
Get full text

Exploring the role of methylation-driven gene IFFO1 in pancreatic adenocarcinoma diagnosis, prognosis and cellular functions by XU Ziqi, HU Ruizhi, LI Junjian, WANG Hongxia, SANG Youzhou

Get full text

DIAGNOSTICS OF COGNITIVE DYSFUNCTION IN PATIENTS IN THE INTENSIVE CARE WARDS by A. A. Ivkin, E. V. Grigoriev, D. L. Shukevich

Subjects: “…cognitive functions…”
Get full text

A Novel Nature-Inspired Optimization Algorithm: Grizzly Bear Fat Increase Optimizer by Moslem Dehghani, Mokhtar Aly, Jose Rodriguez, Ehsan Sheybani, Giti Javidi

Subjects: Get full text

Lymphocyte‐to‐C‐reactive protein ratio and score in patients with heart failure: Nutritional status, physical function, and prognosis by Daichi Maeda, Yuya Matsue, Nobuyuki Kagiyama, Yudai Fujimoto, Tsutomu Sunayama, Taishi Dotare, Taisuke Nakade, Kentaro Jujo, Kazuya Saito, Kentaro Kamiya, Hiroshi Saito, Yuki Ogasahara, Emi Maekawa, Masaaki Konishi, Takeshi Kitai, Kentaro Iwata, Hiroshi Wada, Masaru Hiki, Takatoshi Kasai, Hirofumi Nagamatsu, Tetsuya Ozawa, Katsuya Izawa, Shuhei Yamamoto, Naoki Aizawa, Kazuki Wakaume, Kazuhiro Oka, Shin‐ichi Momomura, Tohru Minamino

“…Nutritional status and physical function were evaluated using several indices and tests. …”
Get full text

Development and Training of Mindfulness and Its Relationship with Executive Function in Chinese Rural Upper-Grade Elementary School Students by Sihui Zheng, Bin Zhang, Haichun Zhou, Mingyi Wang

“…The purpose of this study was to explore the development and relationship between mindfulness and executive function (EF) in students in grades 4–5 and investigate mindfulness training’s impact on mindfulness and EF in grade 4 students in rural China. …”
Get full text