Application of Deep Learning to the Classification of Stokes Profiles: From the Quiet Sun to Sunspots by Ryan J. Campbell, M. Mathioudakis, Carlos Quintero Noda, P. H. Keys, D. Orozco Suárez

“…Asymmetrical (symmetrical) profiles are less (more) common in GREGOR than DKIST or Hinode data, consistent with narrower response functions in the 1564.85 nm line. Single-lobed profiles are extremely rare in GREGOR data. …”
Get full text

Dietary supplementation with glutamate improves the flesh quality of gibel carp (Carassius gibelio) by altering muscle texture characteristics and increasing the deposition of flav... by Wanjie Cai, Xing Wang, Haokun Liu, Luohai Hua, Dong Han, Xiaoming Zhu, Junyan Jin, Zhimin Zhang, Yunxia Yang, Shouqi Xie

“…Metabolomics confirmed that Glu promoted the deposition of muscle-flavoured substances and purine metabolic pathway most functioned, echoed by the upregulation of key genes (ampd, ppat and adsl) in purine metabolism. …”
Get full text

Rapeseed Green Manure Coupled with Biochar and Vermicompost Enhances Soil Aggregates and Fungal Communities in Gleyed Paddy Fields by Zhenhao Zhu, Shihong Gao, Yuhao Zhang, Guohan Si, Xiangyu Xu, Chenglin Peng, Shujun Zhao, Wei Liu, Qiang Zhu, Mingjian Geng

“…The GMB strategy mitigates reductive stress, enhances nutrient availability, and activates microbial functionality. These findings offer insights and frameworks for sustainable soil management in subtropical rice agroecosystems.…”
Get full text

Intravitreal bevacizumab injection alone or combined with macular photocoagulation compared to macular photocoagulation as primary treatment of diabetic macular edema by Jovanović Sandra, Čanadanović Vladimir, Sabo Ana, Grgić Zorka, Mitrović Milena, Rakić Dušan

“…Treatment with bevacizumab alone or within combined treatment is more effective in treating DME than conventional macular laser treatment alone, both anatomically and functionally.…”
Get full text

Good Manufacturing Practice Validation and Radiation Dosimetry for the Clinical Application of a Novel α7-nAChR Radioligand: [¹¹C]KIn83 by Zhisheng Jia, Martin Bolin, Anton Forsberg Morén, Prodip Datta, Heba Asem, Hans Ågren, Bengt Långström, Agneta Nordberg, Christer Halldin, Sangram Nag

“…Nicotinic acetylcholine receptor (α7-nAChR) plays a crucial role in cognitive functions like memory and attention. Positron emission tomography (PET) imaging of α7-nAChR is gaining attraction for understanding and monitoring central nervous system disorders, such as Alzheimer’s disease, Parkinson’s disease, and schizophrenia. …”
Get full text

An enhanced multi-objective reactive power dispatch for hybrid Wind-Solar power system using Archimedes optimization algorithm by Prisma Megantoro, Syahirah Abd Halim, Nor Azwan Mohamed Kamari, Lilik Jamilatul Awalin, Ramizi Mohamed, Hazwani Mohd Rosli

“…The uncertainties of wind and solar power generation were modelled using Weibull and lognormal probability density functions (PDFs), respectively, and the optimization model was tested using a scenario-based method. …”
Get full text

Predictive model for coronavirus disease 2019 severity based on blood biomarkers: a retrospective study by Liu Xiaoyan, Bao Zhongying, Duan Shuhong, Sun Jing, Zhang Yijie, Zhang Jie, Liu Jingxin

“…Emergency department data functioned as an independent external validation set to test the model’s generalizability.ResultsThe study included 1,007 patients, with 778 in the training set and 229 in the validation set. …”
Get full text

Genome Insights into Beneficial Microbial Strains Composing SIMBA Microbial Consortia Applied as Biofertilizers for Maize, Wheat and Tomato by Lisa Cangioli, Silvia Tabacchioni, Andrea Visca, Alessia Fiore, Giuseppe Aprea, Patrizia Ambrosino, Enrico Ercole, Soren Sørensen, Alessio Mengoni, Annamaria Bevivino

“…The annotation of the genomes revealed the presence of genes that are implicated in functions related to antagonism, pathogenesis and other secondary metabolites possibly involved in plant growth promotion and gene clusters for protection against oxidative damage, confirming the plant-growth-promoting (PGP) activity of selected strains. …”
Get full text

Plasma and MRI biomarkers capture neuronal damage in former professional boxers by Suzie Kamps, Suzan van Amerongen, Elena R. Blujdea, Marloes I. Hoppen, Bram Bongers, Kasper H. Schelvis, Dewi K. Caton, Marsh Königs, Charlotte E. Teunissen, Philip Scheltens, Rik Ossenkoppele, Everard G. B. Vijverberg

“…Cognitive performance was assessed in memory and executive functioning (EF) domains. Five boxers had follow-up measurements after ~ 7 years. …”
Get full text

Release Profile and Antibacterial Activity of <i>Thymus sibthorpii</i> Essential Oil-Incorporated, Optimally Stabilized Type I Collagen Hydrogels by Caglar Ersanli, Ioannis Skoufos, Konstantina Fotou, Athina Tzora, Yves Bayon, Despoina Mari, Eleftheria Sarafi, Konstantina Nikolaou, Dimitrios I. Zeugolis

“…Herein, the potential of <i>Thymus sibthorpii</i> EO incorporated in functionalized antibacterial collagen hydrogels was investigated. …”
Get full text

A novel integrated TDLAVOA-XGBoost model for tool wear prediction in lathe and milling operations by Zhongyuan Che, Chong Peng, Chi Wang, Jikun Wang

“…TDLAVOA was validated against classical and modern algorithms on benchmark functions. Subsequently, the XGBoost-TDLAVOA model was developed by employing TDLAVOA to auto-tune seven critical XGBoost hyperparameters using MSE loss, which enhances adaptability and robustness. …”
Get full text

Model Identification, Dynamic Positioning, and Thrust Allocation System for the milliAmpere1 Autonomous Ferry Prototype: Field Trial Results by Miguel Hinostroza, Camilla Fruzzetti, Andreas Gudahl Tufte, Simon J. N. Lexau, Alexey Gusev, Egil Eide, Edmund F. Brekke, Anastasios M. Lekkas, Roger Skjetne, Michele Martelli, Morten Breivik

“…The TA is formulated as a quadratic programming problem, which includes cost functions for power consumption. A third-order reference guidance system is implemented to ensure smooth and continuous signals for the DP desired position, velocity, and acceleration. …”
Get full text

Self-beneficial transactional social dynamics for cooperation in Shwachman-Diamond syndrome: a mixed-subject analysis using computational pragmatics by Arthur Trognon, Arthur Trognon, Arthur Trognon, Natacha Stortini, Natacha Stortini, Coralie Duman, Coralie Duman, Nami Koïdé, Ewa Skupinska, Ewa Skupinska, Hamza Altakroury, Alizée Poli, Alizée Poli, Loann Mahdar-Recorbet, Loann Mahdar-Recorbet, Blandine Beaupain, Jean Donadieu, Michel Musiol, Michel Musiol, Michel Musiol

“…These findings underscore the need for targeted interventions to enhance pragmatic skills and adaptive functioning in SDS, given their unique interaction profiles.…”
Get full text

Development of PD3 and PD3-B for PDEδ inhibition to modulate KRAS activity by Jungeun Lee, Ho Jin Lee, Yeongcheol Lee, Bumhee Lim, Jongsik Gam, Dong-Chan Oh, Jeeyeon Lee

“…For the verification of new therapeutic strategies, chemical probes with the dual functions of visualisation and pharmacological inhibition against oncogenic proteins are enormously valuable to understand cellular events related to cancer. …”
Get full text

Automated protocol templates with efficient schedule of activities table generation for healthy volunteer trials by Kyongeun Shin, Sungpil Han, Hyerim Choe, Suein Choi, Seunghoon Han

“…Additionally, a web-based SoA generator (developed with React.js) was created, featuring user-friendly functions for flexible start day adjustments, trial parameter settings, and automatic annotations. …”
Get full text

PlastidHub: An integrated analysis platform for plastid phylogenomics and comparative genomics by Na-Na Zhang, Gregory W. Stull, Xue-Jie Zhang, Shou-Jin Fan, Ting-Shuang Yi, Xiao-Jian Qu

“…In comparison with existing tools, key novel functionalities in PlastidHub include: (1) standardization of quadripartite structure; (2) improvement of annotation flexibility and consistency; (3) quantitative assessment of annotation completeness; (4) diverse extraction modes for canonical and specialized sequences; (5) intelligent screening of molecular markers for biodiversity studies; (6) gene-level visual comparison of structural variations and annotation completeness. …”
Get full text

An international Phase IV field study - psychometric properties of the updated module on assessing quality of life of patients with breast cancer EORTC QLQ-BR42 by Vesna Bjelic-Radisic, Fatima Cardoso, Joachim Weis, Katarzyna Pogoda, Juan Ignacio Arraras, Elfriede Greimel, Andrew Bottomley, David Cameron, Etienne Brain, Sue Hartup, René Aloisio da Costa Vieira, Nicolette Hoefnagels, Chi-Cheng Huang, Omar Shamieh, Monica Pinto, Yared Belete Belay, Samantha Serpentini, Eveline Bleiker, Manjunath Nookala Krishnamurthy, Akihiko Shimomura, Elisabeth C. Sturm-Inwald, Mikiyas Amare Getu, Brigitte Bliem, Guro Astrup, Ofir Morag, Yuichiro Kikawa, Karin Kuljanic, Nora Nevries, Mirjam Sprangers, Neil K. Aaronson, Parisa Sinai, Krzysztof Tomaszewski, Razvan Galalae, Thierry Conroy, Francois Duhoux, Wei-chu Chie, Galina Velikova

“…The psychometric analyses resulted in a final questionnaire containing 42 items divided into 10 scales: Breast Symptoms, Body Image, Sexual Functioning, Arm Symptoms, Systemic Chemotherapy Side Effects, Hand/Feet Symptoms/Neuropathy, Skeletal Symptoms, Endocrine Symptoms, Breast Satisfaction, Vaginal Symptoms, and 3 single items: Weight Gain, Sexual Enjoyment and Future Perspective. …”
Get full text

Investigation of the stemness and wound-healing potential of long-term cryopreserved stromal vascular fraction cells by Naoki Inafuku, Yoshihiro Sowa, Tsunao Kishida, Seiji Sawai, Edward Hosea Ntege, Toshiaki Numajiri, Kenta Yamamoto, Yusuke Shimizu, Osam Mazda

“…Long-term cryopreservation offers a potential solution by allowing the banking of SVF from younger donors for future use; however, the impact of this process on SVF functionality remains elusive. This study investigates the stemness and wound-healing potential of SVF following prolonged cryopreservation. …”
Get full text

Fusion of SARS-CoV-2 neutralizing LCB1 peptide with Bacillus amyloliquefaciens RNase improves antiviral efficacy by Nikita N. Kostin, Tatyana V. Bobik, Elena V. Konovalova, Milita V. Kocharovskaya, Maria A. Simonova, Natalia Yu Rushkevich, Yuliana A. Mokrushina, George A. Skryabin, Roman S. Kalinin, Sergey I. Kovalchuk, Rustam H. Ziganshin, Leonid A. Kaluzhskiy, Oksana V. Gnedenko, Evgeniy O. Yablokov, Alexis S. Ivanov, Aleksandr S. Chernov, Vitaly A. Kazakov, Oksana N. Khokhlova, Arkady N. Murashev, Senlian Hong, Elena I. Shramova, Alexey A. Schulga, Ekaterina N. Lyukmanova, Mikhail P. Kirpichnikov, Ivan V. Smirnov, Alexey A. Belogurov, Yuri P. Rubtsov, Alexey V. Stepanov, Hongkai Zhang, Alexander G. Gabibov, Sergey M. Deyev

“…However, limited avidity, lack of effector functions, short circulatory half-life, and restricted administration routes make them inferior compared to neutralizing antibodies. …”
Get full text

NRICM101 in combatting COVID-19 induced brain fog: Neuroprotective effects and neurovascular integrity preservation in hACE2 mice by Cher-Chia Chang, Yea-Hwey Wang, Jiin-Cherng Yen, Chia-Ching Liaw, Keng-Chang Tsai, Wen-Chi Wei, Wen-Fei Chiou, Chun-Tang Chiou, Kuo-Tong Liou, Yuh-Chiang Shen, Yi-Chang Su

“…However, NRICM101 treatment in these animals ameliorated all these cognitive functions. S1 protein administration in mice induced notable inflammation, leading to the death of neurons (NeuN+) and neural stem cells (DCX+) in hACE2 transgenic mice. …”
Get full text