PENGEMBANGAN LKPD FUNGSI KUADRAT BERBASIS PEMBUKTIAN DENGAN MODEL ARGUMENTASI TOULMIN UNTUK MEMFASILITASI KEMAMPUAN ARGUMEN MATEMATIS by Debi Suci Putri, Cecil Hiltrimartin, Yusuf Hartono, Nyimas Aisyah

“…The following research aims to obtain proof-based student worksheet on quadratic functions in high school that is valid and practical and has a potential effect on students' mathematical argumentation abilities. …”
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Analytical assessment of metagenomic workflows for pathogen detection with NIST RM 8376 and two sample matrices by Jason G. Kralj, Stephanie L. Servetas, Samuel P. Forry, Monique E. Hunter, Jennifer N. Dootz, Scott A. Jackson

“…Surprisingly, when we compared the linear response of the same taxa in the two different sample types, we found those functions to be the same, despite large differences in LODs. …”
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Positive impact of early-probiotic administration on performance parameters, intestinal health and microbiota populations in broiler chickens by M. Hussain, O. Aizpurua, A. Pérez de Rozas, N. París, M. Guivernau, A. Jofré, N. Tous, Z.W. Ng'ang'a, A. Alberdi, E. Rodríguez-Gallego, M.H. Kogut, J. Tarradas

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The dynamic patterns of groundwater storage in Horqin Sandy Land are driven primarily by climate factors but threatened by human activity by Xueping Chen, Xueyong Zhao, Yanming Zhao, Jiannan Lu, Ruixiong Wang, Xiaowen Zhu, Liya Bai, Yulai Qiao

“…Study focus: This study assessed groundwater storage anomaly (GWSA) in HQSL under climate change and human activity, using Gravity Recovery and Climate Experiment (GRACE) satellite data, Global Land Data Assimilation System (GLDAS) models and in-situ well observations. Herein, Mann–Kendall test, Empirical Orthogonal Functions (EOFs) and Partial Least Squares Structural Equation Modeling (PLS-SEM) model were applied to analyze the seasonal and long-term trend changes of GWSA and quantify the process of GWSA in HQSL. …”
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Development of an Automated Aquarium Monitoring System with an IoT Interface using Google Sheets by Theodore Tochuckwu Chiagunye, Somtochukwu Francis Ilo, Godspower Ikechukwu Ndukwe, Henrietta Uchenna Udeani, Ogobuchi Daniel Okey

“… This paper presents the development of an automated aquarium monitoring system with an IOT interface using google sheets; the system autonomously monitors key water quality parameters temperature, pH, and turbidity while automating fish feeding and water replacement functions. An ESP32 microcontroller serves as the system’s core, control unit which is programmed using C++ to transmit environmental data to a cloud-based Google Sheet. …”
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Prospects of digital scientific publishing on blockchain: The concept of DAP [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved] by Zorislav Šojat, Karolj Skala, Davor Davidović, Josip Maričević, Tomislav Zubčić, Viktor Bojović, Draško Tomić, Branimir Kolarek, Mario Pecimotika, Tadej Slapnik, Dario Pažin

“…Results The DAP platform is in the development phase, with the design and functionalities of all modules defined. An exception is the central component of DAP, the Scholarly Wallet module, whose first prototype has already been created, tested and published. …”
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The Effect of Piracetam Administration on Cerebral Palsy Prevention in Rat Fetuses Born To Pregnant Rats by Determining Bdnf Levels in Brain Tissue by Dudy Aldiansyah, Sarma Nursani Lumbanraja, Khairul Putra Surbakti, Isti Ilmiati Fujiati, Agus Sulistyono

“…Brain-derived neurotrophic factor (BDNF) is potent modulator of many neuronal functions that protect the newborn or developing brain from ischemic injury. …”
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The critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network by Yi Wang, Yi Wang, Moran Xu, Xiaoli Zuo, Sheng Wang, Yong Yu, Zhaobing Gao, Zhaobing Gao, Jingbo Qie, Ye Jiang, Fang Huang, Bingqing Xia, Bingqing Xia

“…However, the mechanisms by which MLKL functions in the process of intracerebral hemorrhage (ICH)-induced damage remain unclear.MethodsHere, we explored the correlation between MLKL and pathological damage in ICH patients through histopathological staining and RT-qPCR. …”
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Characterization and genomic analysis of a Herelleviridae bacteriophage UHP46 infecting mastitis-causing Staphylococcus aureus by Sara Najeeb, Imran Khan, Javed Muhammad, Muhammad Jahangir, Iqbal Ahmad Alvi, Anza Abbas, Aman Ullah, Arif Ullah, Wajiha Sajjad, Hashir Khan, Amjad Khan, Amjad Khan

“…In organic stability test, UHP46 showed stability in DMSO and acetone. …”
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Experiences of Home‐Based Pulmonary Rehabilitation With mHealth and Centre‐Based Pulmonary Rehabilitation in People With Chronic Obstructive Pulmonary Disease: A Qualitative Study... by Hannah Rutherford, Marita Dale, Sally Wootton, Rashmi Pithavadian, Sarah Dennis, Sarah Brown, Jennifer A. Alison, Andrew S. L. Chan, Ian A. Yang, Zoe McKeough

“…Motivators for both programmes included improved fitness levels, feeling accountable to the programme and reinforcement from staff and peers. The m‐PR in‐app functionalities such as the daily task list were additionally motivational. m‐PR participants arranged the programme around their schedule while centred‐based participants arranged their schedule around the programme. …”
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Inhibitory deficits in Klinefelter syndrome are secondary to deficits in the auditory and motor domain by René J. Huster, Christina Thunberg, Anne-Kristin Solbakk, Claus H. Gravholt, Krister Fjermestad

“…Verbal deficits are among the most characteristic cognitive impairments of KS, yet other cognitive domains also exhibit deficits. Executive functions, especially working memory capacity and inhibitory control, are frequently affected as well. …”
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Cognitive deficits in treatment-resistant depression: protocol for a systematic review and meta-analysis by Maximilian Kiebs, Richard Porter, Katie Douglas, Eivind Haga Ronold, Daniel Jensen, Anders Lillevik L Thorsen, Rune Raudeberg, Leif Oltedal, Åsa Hammar, Marco Hirnstein

“…It is expected that TRD will show more severe cognitive deficits than generally reported in MDD and deficits in all cognitive functions are expected.Methods and Analysis A systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines will be performed of the databases Embase, Pubmed/MEDLINE, PsychINFO and Cochrane including peer-reviewed studies on humans using standardised cognitive tests. …”
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Significant Inverse Correlation of Serum Levels of Osteoprotegerin (OPG) and Transferrin Saturation in Thalassemia Dependent Transfusion (TDT) Patients by Indra Wijaya, M Lucky Nurdiansyah Prameswara, Dimmy Prasetya, Laniyati Hamijoyo, Bachti Alisjahbana, Andri Reza Rahmadi

“…OPG is a glycoprotein that functions as a feedback receptor for the Receptor Activator of Nuclear Factor kappa B Ligand (RANKL), which is an alpha tumor necrosis factor receptor. …”
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Utilization of universal-targeting mSA2 CAR-T cells for the treatment of glioblastoma by Alexandros Kourtesakis, Eileen Bailey, Hiu Nam Hannah Chow, Hannah Rohdjeß, Normann Mussnig, Dennis Alexander Agardy, Dirk Carsten Frieder Hoffmann, Yu-Chan Chih, Rainer Will, Leon Kaulen, Melissa Hahn, Robin Wagener, Denise Reibold, Sonja Pusch, Felix Sahm, Tim Sauer, Michael Schmitt, Lukas Bunse, Michael Platten, Wolfgang Wick, Tobias Kessler

“…Finally, the mSA2 CAR-T cell-mediated anti-tumor functions were demonstrated in vivo. Immunocompromised mice orthotopically implanted with CD70+ or CD276+ GB cells and treated with mSA2 CAR-T cells pre-armed with antibodies against these two antigens exhibited control of tumor growth and induction of GB cell apoptosis after therapy. …”
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Development of Speech and Communication in Polish Children with 22q11.2 Deletion Syndrome: A Cross-Sectional Study by Natalia Moćko, Marcin Rudzki, Zuzanna Miodońska, Julia Olesiak, Katarzyna Jochymczyk-Woźniak, Michał Kręcichwost

“…Methods: Individuals affected with 22q11DS may show difficulties in functioning, including speech and hearing. Therefore, we prepared a speech development questionnaire and employed it to obtain data from parents (or legal guardians) of 54 children with 22q11DS. …”
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Targeted Delivery of Bortezomib Using Retinoid-Based Nanoparticle: Modulating Liver Fibrosis through the TGF-β1/Smad3 Pathway by Samaneh Siapoush, Mohammad Rahmati, Morteza Milani, Behzad Hatami, Nosratollah Zarghami, Abbas Ebrahimi-Kalan, Mohammad Reza Zali, Kaveh Baghaei

“…Purpose: Hepatic stellate cells (HSCs) play a crucial role in fibrosis progression. we have developed a targeted delivery approach using A-functionalized nanoparticles for bortezomib (BTZ) specifically for activated HSCs in a mouse model of liver fibrosis. …”
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Design, Fabrication, and Performance Evaluation of a Food Solar Dryer by Md. Suman Rana, A. N. M. Arifur Rahman, Rakib Ahmed, Md. Pallob Hossain, Md. Salim Shadman, Pranta Kumar Majumdar, Kh. Shafiqul Islam, Jonathan Colton

“…The dryer was produced and tested within the context of Bangladesh, unlike other commercial devices. …”
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In-depth chromatographic and spectrally defined phytocompounds in super-critical-CO2 extracted Phyllanthus emblica seeds oil show robust anti-microbial/biofilm effects in the non-m... by Acharya Balkrishna, Priya Rani Maheswari, Monali Joshi, Yash Varshney, Himanshu Jangid, Manisha Kabdwal, Savita Lochab, Pardeep Nain, Anurag Varshney

“…Additionally, the Ames assay, a bacterial mutagenicity test, showed that PeSSO is non-mutagenic in nature. …”
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Ketorolac, melatonin and latanoprost tri-loaded PLGA microspheres for neuroprotection in glaucoma by Miriam Ana González-Cela-Casamayor, María J. Rodrigo, Marco Brugnera, Inés Munuera, Teresa Martínez-Rincón, Catalina Prats-Lluís, Pilar Villacampa, Julián García-Feijoo, Luis E. Pablo, Irene Bravo-Osuna, Elena Garcia-Martin, Rocío Herrero-Vanrell

“…Treated glaucomatous rats reached the lowest intraocular pressure, enhanced functionality of bipolar and retinal ganglion cells and showed greater neuroretinal thickness by optical coherence tomography (p < 0.05) compared to not treated glaucomatous rats at 24 weeks follow-up. …”
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Changes in the distribution of elements in the liver and various brain regions in suicides from southeastern Poland by Jacek Baj, Alicja Forma, Kaja Karakuła, Wojciech Flieger, Michał Flieger, Beata Kowalska, Iwona Kamińska, Dariusz Majerek, Grzegorz Teresiński, Ryszard Maciejewski, Elżbieta Radzikowska-Büchner, Jolanta Flieger

“…Many of them play a key role in the proper functioning of the brain by controlling oxidative metabolism, neurotransmission and the production of neurotransmitters. …”
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