Coexposure to microplastic and Bisphenol A exhacerbates damage to human kidney proximal tubular cells by Daniela Verzola, Noemi Rumeo, Stefano Alberti, Fabrizio Loiacono, Sebastiano La Maestra, Mario Passalacqua, Cristina Artini, Elisa Russo, Enrico Verrina, Andrea Angeletti, Simona Matarese, Nicoletta Mancianti, Paolo Cravedi, Micaela Gentile, Francesca Viazzi, Pasquale Esposito, Edoardo La Porta

“…In addition, heat shock protein (HSP90), a chaperone involved in multiple cellular functions, was reduced (by Western Blot and immunocytochemistry), while aryl hydrocarbon receptor (AHR) expression, a transcription factor which binds environmental ligands, was increased (RT-PCR and immunofluorescence). …”
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Digital transformation of population administration: Enhancing data accessibility in local communities by Ozzi Suria, Putri Taqwa Prasetyaningrum, Irfan Pratama

“…In the evaluation phase, the system was tested and refined based on feedback from the community leader to ensure functionality and usability. …”
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Development of Secure API to Support ICD-10 Based Electronic Medical Records Interoperability by I Gusti Ngurah Lanang Wijayakusuma, Made Sudarma, I Ketut Gede Darma Putra, Oka Sudana, Minho Jo, I Putu Winada Gautama

“…To address this, the research team has devised the Application Programming Interface (API). Functioning as a crucial bridge, this API facilitates interoperability among diverse systems. …”
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Synthesis of Antimicrobial and Antioxidant Zinc Oxide Hydrogel for Drug Delivery Applications by Krithika Ramesh, Jeyanthi Ponnusamy, Pazhanisamy Periasamy

“…The hydrogel's water solubility, non-toxicity, and antioxidant properties suggest it could be safe and effective throughout the drug delivery process, contributing both passive and reactive targeting functions.…”
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Indicator‐based natural capital reporting to inform decision‐making in the Brazilian Pantanal by Alison J. Fairbrass, Victor Moretti, Elvander Quaresma, Celma Ribeiro, Fabio deOliveira Roque, Claudio Oller, Julia Tomei

“…However, we identify significant gaps in indicators on the condition and economic value of the biome, the human investment required to derive benefits from the biome, emissions produced by the industries that exploit the biome, and the ecosystem services that maintain the functioning of the biome, such as nutrient cycling and biodiversity. …”
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Probiotic Lactobacillus Strains Stimulate the Inflammatory Response and Activate Human Macrophages by L. M. Rocha-Ramírez, R. A. Pérez-Solano, S. L. Castañón-Alonso, S. S. Moreno Guerrero, A. Ramírez Pacheco, M. García Garibay, C. Eslava

“…Lactobacilli have been shown to promote health functions. In this study, we analyzed the mechanism by which four different strains of probiotics affected innate immunity, such as regulation of ROS, cytokines, phagocytosis, bactericidal activity, signaling by NF-κB pp65, and TLR2 activation. …”
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A Multi-Strategy Adaptive Coati Optimization Algorithm for Constrained Optimization Engineering Design Problems by Xingtao Wu, Yunfei Ding, Lin Wang, Hongwei Zhang

“…Comparative experiments with many existing algorithms are conducted using the CEC2017 test functions, and the proposed algorithm is applied to seven representative engineering design problems. …”
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AetherGeo: A Spectral Analysis Interface for Geologic Mapping by Gonçalo Santos, Joana Cardoso-Fernandes, Ana C. Teodoro

“…It provides the user with a set of tools for spectral data analysis through classical approaches, such as band ratios and RGB combinations, but also more elaborate techniques, such as endmember extraction and unsupervised image classification with partial spectral unmixing techniques. While it has been tested on visible and near-infrared (VNIR), short-wave infrared (SWIR), and VNIR-SWIR datasets, the functions implemented have the potential to be applied to other spectral ranges. …”
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Design and Fabrication of Cylindrical Fiber Backplanes with 2T1C Pixel Circuits for Truly Wearable Woven Displays by Jiseong Lee, Soyoon Park, Seong Uk Kong, Jiwoo Park, Daehyun Kim, Kyung Cheol Choi

“…This design demonstrates exceptional potential for high‐density integration, advanced functionality, and scalability in next‐generation electronic systems. …”
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A UV-C LED Lamp Driver Circuit Applied to a Direct-Current-Input Voltage Source for Sterilization and Germicidal Applications by Chun-An Cheng, Chien-Hsuan Chang, Hung-Liang Cheng, En-Chih Chang, Wen-Yi Yan, Long-Fu Lan

“…The experimental results from the prototype circuit, tested at an 18 V DC input, confirm the functionality of the proposed electronic driver for UV-C LED sterilization and germicidal lighting. …”
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Reference for determining Phillip's constant values and peak enhancement factor for the use of JONSWAP spectrum in Western Java Sea waters by Satriyo Panalaran, Suntoyo, Aries Sulisetyono, Dhany Arifianto, Andri Ramdhani, Widi Agoes Pratikto

“…The procedures carried out in this study include: adjustment of the values of the key parameters of the JONSWAP spectrum (α and γ); matching against a number of spectrum models; evaluation of the distribution functions to define the values of α and γ; as well sensitivity test. …”
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A Framework for Business Model Design by Porrandokht Niroomand, Mahbobeh Ranjbar, Seyed Mohamad Aeraby, Behnaz Hajisadeghi

“…Finallywhile introducing a recommended model for designing a business model;business model functions have investigated in conceptual framework. …”
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On the Flow Behavior in Rotor-Stator System with Superposed Flow by Roger Debuchy, Fadi Abdel Nour, Gérard Bois

“…Thus, two innovative weighting functions are tested, leading to new analytical laws relating the core swirl ratio K to the coefficient of flow rate Cqr introduced by Poncet et al. (2005). …”
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Nonalcoholic Steatohepatitis in a Patient with Ataxia-Telangiectasia by Trinidad Caballero, Mercedes Caba-Molina, Javier Salmerón, Mercedes Gómez-Morales

“…A-T patients have inactivation of ataxia-telangiectasia-mutated (ATM) protein, which controls DNA double-strand break repair and is involved in oxidative stress response, among other functions; dysfunctional control of reactive oxygen species may be responsible for many of the clinical manifestations of this disease. …”
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De Novo Assembly, Characterization and Comparative Transcriptome Analysis of the Mature Male and Female Gonads in <i>Acrossocheilus parallens</i> by Weiqian Liang, Lanyuan Liu, Dingxian Chen, Kaifeng Wang, Shengyue Lin, Weijian Chen, Sixun Li, Binhua Deng, Qiang Li, Chong Han

“…These results provide basic data for further research on the functions of the genes and pathways related to sex differentiation and gonad development in <i>A. parallens</i>.…”
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Genetic and molecular insights in oral squamous cell carcinoma therapy - Advancing the horizon by Prathiksha Srikanthan, Suresh Malakondaiah, Iadalin Ryntathiang, Mukesh Kumar Dharmalingam Jothinathan

“…Research shows that PD-1/PD-L1 inhibitors have the possibility to be used in OSCC treatment, and they mainly focus on improving immune functions. In this regard, salivary biomarkers provide early detection approaches with high sensitivity, especially chemerin and matrix metalloproteinase (MMP-9). …”
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Design and validation of a selective binding 3D printer for bio-based construction materials by Valentine Danché, Mamma Bouaouich, Abdeslam Benamara, Alexandre Pierre, Khadim Ndiaye, T.T. Ngo

“…This study offers a new design that accepts different powder and bio-based materials to enhance the functionality of construction elements. We developed a system in which a numerical controlled machine is coupled with a 6 axis articulated-arm to selectively bind a mineral powder bed with liquid's droplets. …”
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Smart Leather Using Thermoresponsive Cholesteric Liquid Crystals in Surface Finishing by Cosmin-Andrei Alexe, Carmen Gaidau, Ioana Rodica Stanculescu, Cristina Burducea, Viorel Cîrcu

“…The chromatic transition properties responsive to various external stimuli have become not only of great aesthetic value but also a first step toward smart sensor functions, for thermal, pressure or environmental toxicity warning. …”
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Design of improved JAYA algorithm for cigarette finished product logistics delivery by Jun Wen, Yewei Hu, Le Li, Zongrui Wu, Guangwei Xiao, Kai Guo, Lei Li

“…Experimental results demonstrated that the improved Jaya algorithm achieved approximately 40 %-60 % faster convergence compared to the traditional Jaya algorithm and the dynamic segmentation-based sine cosine algorithm across multiple benchmark test functions. In real-world cigarette logistics distribution scenarios, the improved algorithm reduced total distribution mileage by approximately 21 %, lowered fuel consumption by about 29 %, shortened delivery time by approximately 16 %, and increased on-time delivery rates by 7 %-12 %. …”
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Correction of oxidative stress enhances enzyme replacement therapy in Pompe disease by Antonietta Tarallo, Carla Damiano, Sandra Strollo, Nadia Minopoli, Alessia Indrieri, Elena Polishchuk, Francesca Zappa, Edoardo Nusco, Simona Fecarotta, Caterina Porto, Marcella Coletta, Roberta Iacono, Marco Moracci, Roman Polishchuk, Diego Luis Medina, Paola Imbimbo, Daria Maria Monti, Maria Antonietta De Matteis, Giancarlo Parenti

“…In addition to glycogen storage, secondary dysregulation of cellular functions, such as autophagy and oxidative stress, contributes to the disease pathophysiology. …”
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