Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations. by Chisom Soremekun, Tafadzwa Machipisa, Opeyemi Soremekun, Fraser Pirie, Nashiru Oyekanmi, Ayesha A Motala, Tinashe Chikowore, Segun Fatumo

“…<h4>Background</h4>Liver disease is any condition that causes liver damage and inflammation and may likely affect the function of the liver. Vital biochemical screening tools that can be used to evaluate the health of the liver and help diagnose, prevent, monitor, and control the development of liver disease are known as liver function tests (LFT). …”
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Simvastatin-Loaded Chitosan-Functionalized PLGA Nanoparticles: Characterization and Use in Intimal Hyperplasia Therapy by Ashley A. Peters, Chanpreet Kaur, Maleen Cabe, Kelly A. Langert, Kristopher Maier, Vivian Gahtan

“…<b>Background</b>: Statins have beneficial pleiotropic effects, including reducing intimal hyperplasia (IH), but off-target effects remain a concern. Here, we tested the hypothesis that chitosan-functionalized polymeric nanoparticles (NPs) loaded with simvastatin (SL-cNPs) would (1) readily associate with endothelial cells (ECs) and vascular smooth muscle cells (VSMCs); (2) affect EC and VSMC function; and (3) reduce IH compared to systemic simvastatin. …”
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FUNCTIONAL STATE OF THE MASTICATORY MUSCLES OF PATIENTS WITH DEFECTS OF DENTITION, WHICH ARE COMPLICATED BY DENTOALVEOLAR DEFORMITIES by O. V. Bida, Yu. I. Zabuha

“…Morphological disorders are accompanied by functional violations of biodynamic balance of masticatory muscles, often in the stage of decompensation. …”
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Prospective Evaluation of the Impact of Sedation During LAAO on Cognitive Function Using Oculomotor Biomarkers by Agata Sularz, MB, BChir, Alejandra Chavez-Ponce, MD, Ghasaq Saleh, MD, Gurpreet Singh, MD, Bilal Unar, MD, Trevor Simard, MD, Matias Shulz, MScEng, Gerardo Fernandez, PhD, Danilo Verge, MD, MBA, Mohamad Alkhouli, MD, MBA

“…We examined differences in cognitive function as measured by 2 oculomotor tests (Go/No Go and N-Back), within each group between V1 vs V2 and V1 vs V3. …”
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Dysphagia is a strong predictor of death and functional dependence at three months post-stroke by Aline Cristina PACHECO-CASTILHO, Rubia Poliana Crisóstomo MIRANDA, Ana Maria Queirós NORBERTO, Diandra Bosi FAVORETTO, Brunna Pileggi RIMOLI, Luciana Bezerra de Mello ALVES, Karina Tavares WEBER, Taiza Elaine Grespan SANTOS, Julio Cesar MORIGUTI, João Pereira LEITE, Roberto Oliveira DANTAS, Rosemary MARTINO, Octávio Marques PONTES-NETO

“…Swallowing was evaluated by speech language pathologists using Volume-Viscosity Swallow Test. General function at three months post-stroke was assessed using the following instruments: Modified Rankin scale, Barthel Index and Functional Independence Measure. …”
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The Use of Diagnostic Transcranial Magnetic Stimulation as a Predictor of the Functional Outcome in Ischemic Stroke by I. V. Pogonchenkova, S. S. Petrikov, E. V. Kostenko, A. G. Kashezhev, L. V. Petrova, M. V. Sinkin

“…Navigational transcranial magnetic stimulation (nTMS) has been proposed as a method for PR determination in after-stroke patients.THE AIM. was to study the importance of navigational diagnostic transcranial magnetic stimulation as a neurofunctional predictor of motor function recovery after ischemic stroke.MATERIAL AND METHODS. …”
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Functional Outcome of Arthroscopic Anterior Cruciate Ligament Reconstruction Using Quadriceps Tendon Autograft by Varrdhaman H Dhariwal, Ashokan Chandran, Aravinth Thamizholi, Ajith Kumar, Mohan K Kannaiyan

“…Aims and background: To analyze the functional outcomes of anterior cruciate ligament (ACL) reconstruction arthroscopically using a quadriceps tendon (QT) graft, the assessment is conducted based on standardized scoring systems. …”
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Urine Periostin Level and Renal Function in Malignancy Patients Treated with High-Dose Cisplatine by Harry Yusuf, Andhika Rachman, M Bonar Marbun, Hamzah Shatri, Putri Aliya Ahadini

“…Urine periostin levels and other kidney function indicators did not significantly correlate (p>0.05), according to the correlation test, and several domains had negative directions. …”
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FUNCTIONAL AND METABOLIC FEATURES OF BLOOD PHAGOCYTES AT DIFFERENT FORMS OF TUBERCULAR INFLAMMATORY PROCESS OF LUNGS by O. V. Berdyugina, A. V. Yershova

“…Various clinical variants of tubercular inflammatory process necessitate further studies of functional and metabolic features of blood phagocytes in the patients with different forms of lung tuberculosis, being the main goal of this study. …”
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Sex differences in loneliness, social isolation, and their impact on psychiatric symptoms and cognitive functioning in schizophrenia by Jinghui Chi, Nannan Liu, Tian Tian, Qiaona Jiang, Chenghao Lu, Yanzhe Li, Xiaofei Zhang, Yanyan Ma, Lili Wang, Shen Li

“…This study aimed to explore sex differences in loneliness and social isolation among Chinese chronic SCZ patients, and to investigate their relationships with psychiatric symptoms and cognitive functioning. Methods A total of 323 SCZ patients, comprising 136 males and 187 females, were recruited. …”
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Association between physical activity and executive function of Chinese adolescents aged 13–18 by Yuan Liu, Xiaojian Yin, Yi Sun, Feng Zhang, Feng Zhang, Cunjian Bi, Yaru Guo, Yaru Guo, Pengwei Sun, Pengwei Sun, Hong Jun, Hong Jun, Yanyan Hu, Yanyan Hu, He Liu, He Liu

“…Participants completed execution function test and PA questionnaire survey. Data were analyzed using one-way ANOVA, Pearson correlation analysis, and 30-minute isotemporal substitution models (ISM) to assess the association between PA and EF.ResultsDaily moderate-to-vigorous physical activity (MVPA) time in both boys and girls was negatively correlated with inhibitory control RTs (r = −0.279, −0.173, P &lt; 0.01), 2back-RTs (r = −0.367, −0.268, P &lt; 0.01), and cognitive flexibility RTs (r = −0.283, −0.305, P &lt; 0.01). …”
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Pharmacogenetics of statin therapy and the endothelial function parameters in patients with type 2 diabetes mellitus by Nadezhda O. Lebedeva, Olga K. Vikulova, Alexei G. Nikitin, Minara Sh. Shamkhalova, Marina V. Shestakova, Ivan I. Dedov

“…To investigate the association of variation in lipid-lowering response and endothelial function (EF) parameters after atorvastatin therapy in patients with type 2 diabetes mellitus (T2DM) with genetic markers of atherosclerosis.Methods. …”
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Association between oxidative balance score and lung function and FeNO and mortality in the US population by Chang Liu, Dan Liang, Guoan Xiang, Kun Xiao, Lixin Xie

“…A limited number of studies have examined the association between OBS and lung function and FeNO, and we aimed to investigate the possible relationship between OBS and lung function and FeNO. …”
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The role of dietary monoglycerides and tributyrin in enhancing performance and intestinal health function in nursery piglets by Keila Abadia Barbosa, Jansller Luiz Genova, Mayara Larissa Pazdziora, Julia Fairuz Hennig, Liliana Bury de Azevedo, Bruno Rafael de Melo Veiga, Gustavo de Amorim Rodrigues, Silvana Teixeira Carvalho, Diovani Paiano, Alysson Saraiva, Newton Tavares Escocard de Oliveira, Paulo Levi de Oliveira Carvalho

“…This study was conducted to assess the effects of dietary monoglycerides and tributyrin on performance, blood metabolites, and intestinal health function in nursery piglets. A total of 96 crossbred entire male piglets (7.70 ± 0.49 kg) were allotted for 35 d in a complete block design to one of four treatments: (1) negative control (NC): no feed additive, (2) positive control (PC) containing 60 mg halquinol/kg diet, (3) diet containing 2 g monoglyceride blend/kg diet (MGD), and (4) diet containing 2 g tributyrin/kg diet (TBT). …”
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Endothelial Dysfunction, Functional Structural Changes in the Vessels in Patients with the Unstable Angina with Arterial Hypertension by Denesiuk O.

“…One of the most actual problems of modern cardiology is the study of endothelial function, functional and structural changes in arteries, especially in patients with arterial hypertension (AH), the atherosclerotic process primarily affects the arteries of the elastic type (aorta) and slightly less – of the muscle type (brachial artery). …”
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Relationship between indicators of carotid artery rigidity and cognitive functions in arterial hypertension patients by N. Ya. Dotsenko, S. S. Boev, I. A. Shekhunova, A. V. Molodan, L. V. Gerasimenko, A. Ya. Malynovskaya

“…The Montreal Scale (MoCA test) was used to assess cognitive functions. The state of the carotid artery was studied with the help of sonography with recording the thickness of the intima-media complex; Peterson and Young modules, linear tensile properties, radial tension of the vessel wall, parameter β, local pulse wave velocity were calculated. …”
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Effect of vestibular symptoms on balance and walking function in patients with acute brain stem infarction by HUANG Mao‐juan, CUI Li‐ling, WANG Fei, CHEN Jun‐ying, ZHANG Yue, WU Jia‐ling

“…Objective To investigate the correlation between vestibular symptoms and balance/ walking function in patients with acute brain stem infarction. …”
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Anatomical and functional study of the musculus psoas major and nervus femoralis in correlation with pelvic diameters by Vojvodić Aleksandar, Matić Aleksandar, Mihailović Jelena, Bjelogrlić Predrag, Puškaš Laslo, Stijak Lazar, Aleksić Dubravka, Filipović Branka, Vukomanović-Đurđević Biserka, Kapor Slobodan

“…This muscle is the major flexor of the hip joint, and it is functionally essential for proper posture, walking, running, and other physical activities. …”
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Gut microbiota regulates exercise-induced hormetic modulation of cognitive functionResearch in context by Elisa Cintado, Pablo Muela, Lucía Martín-Rodríguez, Ignacio Alcaide, Patricia Tezanos, Klara Vlckova, Benjamín Valderrama, Thomaz F.S. Bastiaanssen, María Rodríguez-Muñoz, María L. de Ceballos, María R. Aburto, John F. Cryan, José Luis Trejo

“…Summary: Background: Lifestyle factors, particularly physical exercise, significantly influence brain structure and cognitive function through a hormetic effect —a phenomenon where low to moderate doses of a stimulus (in this case, exercise) induce beneficial adaptations, while excessive doses could lead to detrimental effects. …”
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Fc-effector functional antibody assays for SARS-CoV-2 variants of concern by Xuemin Chen, Grace Li, Caroline Ciric, Theda Gibson, Larry J. Anderson, Larry J. Anderson, Christina A. Rostad, Christina A. Rostad

“…The greatest increase in neutralizing antibodies was against the XBB.1.5 strain, while Fc-effector functional antibodies had similar fold-increases in antibody titers against the breadth of SARS-CoV-2 variants tested. …”
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