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Suggested Topics within your search.
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2381
Effects of N-glycosylation site removal in archaellins on the assembly and function of archaella in Methanococcus maripaludis.
Published 2015-01-01“…Disruption of the N-linked glycosylation pathway is known to cause defects in archaella assembly or function. Here, we explored the potential requirement of N-glycosylation of archaellins on archaellation by investigating the effects of eliminating the 4 N-glycosylation sites in the wildtype FlaB2S2 protein in all possible combinations either by Asn to Glu (N to Q) substitution or Asn to Asp (N to D) substitutions of the N-glycosylation sequon asparagine. …”
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2382
Lateralization of memory function in temporal lobe epilepsy using scene memory fMRI
Published 2024-12-01“…Abstract Functional magnetic resonance imaging (fMRI) offers an alternative to the traditional Wada test for presurgical language and memory lateralization that carries almost no risk. …”
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2383
Mechanical Design of a Novel Functionally Graded Lattice Structure for Long Bone Scaffolds
Published 2025-05-01“…The implantation of porous scaffolds is essential for treating large bone defects and must mimic natural bone’s geometric and mechanical behaviour. Functionally graded lattice structures offer spatial variation in mechanical properties, making them suitable for biomedical applications. …”
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2384
Synergistic effects produced by certain antioxidants in valuable functional foods from the Romanian markets
Published 2025-06-01“…Today, people should change their lifestyles and nutrition to prevent metabolic diseases characteristic of our century. Functional foods, rich in antioxidants, greatly help combat everyday stress and ensure optimal nutritional density. …”
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2385
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2386
Non-employment over the working life: Implications for cognitive function and decline in later life
Published 2025-06-01“…Linear regression was used to test associations between non-employment duration and cognitive function at age 60–64, and conditional change models were used to examine associations between non-employment and cognitive decline from age 60–64 to 69. …”
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2387
A Surrogate Piecewise Linear Loss Function for Contextual Stochastic Linear Programs in Transport
Published 2025-06-01“…To address this limitation, inspired by the smart predict-then-optimize framework, we introduce a novel tunable piecewise linear loss function (PLLF). Rather than directly incorporating decision loss into the learning objective based on specific problem, PLLF serves as a general feedback mechanism that guides the prediction model based on the structure and sensitivity of the downstream optimization task. …”
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2388
Developmental family functions and cognitive emotion regulation in adolescents with conduct disorder and normal peers
Published 2025-06-01“…The results of all MANOVA significance tests were positive, indicating that the subscales of family developmental functioning and cognitive emotion regulation strategies have a multivariate effect on the severity of conduct disorder symptoms. …”
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2389
The Effect of Eight Weeks Pilates Training on Functional Indicators and Postural Abnormalities in Older Men
Published 2025-01-01“…This study investigates the effect of eight weeks of Pilates exercise training on functional indicators and postural abnormalities in older men. …”
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2390
The Effect of Psychological Stress on Mucosal IL-6 and Helicobacter pylori Activity in Functional Dyspepsia
Published 2017-08-01“…The correlation of each variable in the group experiencing psychological stress and non-stress was analyzed using Chi-square test. Results: there were 40 patients with functional dyspepsia with average age of 37.58(SD 11.82) years old. …”
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2391
Curcumin Promotes the Recovery of Motor Function After Brachial Plexus Avulsion Injury in Rats
Published 2025-08-01“…After conducting the Terzis grooming test (TGT) to assess the recovery of motor function, the anterior horn of the spinal cord was collected for detecting the inflammatory responses using Western blot, the musculocutaneous nerves were collected for detecting the motor neuron survival and myelination using Luxol fast blue (LFB) staining or real‐time quantitative PCR (qRT‐PCR), and the biceps brachii were collected for detecting muscle atrophy using hematoxylin and eosin (H&E) staining. …”
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2392
Study on Friction and Wear Performance of Bionic Function Surface in High-Speed Ball Milling
Published 2025-07-01“…This study confirms the feasibility of fabricating biomimetic functional surfaces via high-speed ball-end milling and establishes an integrated surface engineering approach combining biomimetic design, efficient manufacturing, and parameter optimization. …”
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2393
Importance of the actual plant height in modulating the within-community spectrum of plant form and function
Published 2025-07-01“…Maximum height (Hmax) is a principal driver or correlate of interspecific variation in many plant functional traits. Still, it remains unclear why leaf resource economic traits are invariant with Hmax at global scale and why broad-scale interspecific trait correlations are not retained at local scale. …”
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2394
Effects of prior air pollution exposure on functional recovery after a myocardial infarction
Published 2025-01-01“…Air pollution is a major cardiovascular risk factor leading to higher rates of heart failure and myocardial infarction (MI), but its effects on functional recovery after an MI remain unknown. Cardiac rehabilitation is a cornerstone of post-MI care and leads to better performance and quality of life, but its benefits may be hampered in heavily polluted environments. …”
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2395
Direction-aware functional class scoring enrichment analysis of infinium DNA methylation data
Published 2024-12-01“…Infinium Methylation BeadChip arrays remain one of the most popular platforms for epigenome-wide association studies, but tools for downstream pathway analysis have their limitations. Functional class scoring (FCS) is a group of pathway enrichment techniques that involve the ranking of genes and evaluation of their collective regulation in biological systems, but the implementations described for Infinium methylation array data do not retain direction information, which is important for mechanistic understanding of genomic regulation. …”
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2396
Melatonin Improves Quality of Life, Oxidative Stress, and Cardiovascular Function in Pulmonary Arterial Hypertension
Published 2025-04-01“…The principal endpoint was change in walking distance (WD) in the 6‐min walking test (6MWT). Secondary endpoints were functional class (FC), quality of life (QoL), performance of right ventricle (RV), and plasma antioxidant capacity. …”
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2397
Pain and functional disability after lumbar microdiscectomy and their correlations with gender, depression and recovery expectations
Published 2022-01-01“…The following questionnaires were used for examinations: for assessment of pain and its intensity and character – PainDETECT Test; for functional disability – Oswestry Low Back Pain Disability Questionnaire; for the presence and degree of depression – Beck Depression Inventory-II; and questionnaire for the assessment of personal expectations (pessimistic/optimistic) about the treatment results. …”
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2398
Human Clustering Based on Graph Embedding and Space Functions of Trajectory Stay Points on Campus
Published 2025-03-01“…These methods are not effective in revealing human groups who move among spaces at different locations but with the same functions. Function, as one semantic attribute of spaces, is a major driver of most human movements. …”
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2399
The combined effects of sleep and extreme heat exposure on cognitive function among older adults
Published 2025-01-01“…Extreme heat was defined as periods ≥ 3 days with daily minimum temperatures above the 92.5th percentile during the warm season. Cognitive function was assessed with the Mini-Mental State Examination (MMSE). …”
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2400
Spillover Effects of Paid Functions on Physicians’ Unpaid Knowledge Activities: Quasi-Experimental Approach
Published 2024-12-01“…The paid function led to a decrease in the consistency between titles and content (–115.5%; P<.001). …”
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