Development and Validation of a Brain Aging Biomarker in Middle-Aged and Older Adults: Deep Learning Approach by Zihan Li, Jun Li, Jiahui Li, Mengying Wang, Andi Xu, Yushu Huang, Qi Yu, Lingzhi Zhang, Yingjun Li, Zilin Li, Xifeng Wu, Jiajun Bu, Wenyuan Li

“…Brain age gap exhibited clinical feasibility combined with Functional Activities Questionnaire, with improved discriminative capacity in models achieving lower MAEs (AUC of 0.945 vs 0.923 and 0.911; AUC of 0.935 vs 0.900 and 0.881). …”
Get full text

Evaluation of the Antistaphylococcal Activity of the Pyrimidine Derivative by A. A. Tsibizova, A. L. Yasenyavskaya, I. N. Tyurenkov, A. A. Ozerov, O. A. Baskina, M. A. Samotrueva

“…Also, the advantage of pyrimidines is the simplicity of the synthesis of new compounds based on them by attaching various functional groups to the heterocycle.Aim. Evaluation of antistaphylococcal activity of a new pyrimidine derivative in vitro and in vivo.Materials and methods. …”
Get full text

Features of Changes of Main Indices in Acne Patients Systemic Immunity and Their Dependence on Clinical Forms of Dermatosis Course by Syzon O., Dashko M.

“…Acne is a chronic recurrent dermatosis represented with a complex of multifactorial subjective and objective symptoms pathogenetically united in a pathologic process, which is accompanied by the functional abnormalities of sebaceous glands and propagation of Propionibacterium acne, psycho-emotional disorders, and torpidity of treatment. …”
Get full text

EEG-fMRI neurofeedback versus motor imagery after stroke, a randomized controlled trial by Simon Butet, Mathis Fleury, Quentin Duché, Elise Bannier, Giulia Lioi, Lou Scotto di Covella, Emilie Lévêque-Le Bars, Anatole Lécuyer, Pierre Maurel, Isabelle Bonan

“…Thirty stroke survivors, exhibiting partial upper-limb motor impairment with a Fugl-Meyer Assessment Upper Extremity score (FMA-UE) > 21 and partially functional corticospinal tract (CST) were randomly allocated to the NF and MI groups. …”
Get full text

PRALINE: study protocol for a phase IIb inpatient stroke rehabilitation randomized controlled trial investigating longitudinal outcomes after progressive abduction loading therapy by Heidi R. Roth, Carolina Carmona, Gina Clark, Jane E. Gyarmaty, Julius P. A. Dewald, Elise Giblin, Richard L. Harvey, Jacquelyn Jaskiewicz, Kwang-Youn A. Kim, Nicola Lancki, Alexis Luhrsen, Ahalya Mandana, Deepali Manikonda, Andrew Morris, Sonia Sheth, Mary Ellen Stoykov, Amanda C. Young, Donna Zielke, Michael D. Ellis

“…Primary outcomes include change in reaching function of the affected upper extremity, measured by kinematic evaluation. …”
Get full text

The right temporoparietal junction during a cooperation dilemma: An rTMS study by Shisei Tei, Junya Fujino, Takashi Itahashi, Yuta Y. Aoki, Haruhisa Ohta, Manabu Kubota, Shuji Sawajiri, Ryu-ichiro Hashimoto, Hidehiko Takahashi, Nobumasa Kato, Motoaki Nakamura

“…Although published functional magnetic resonance imaging studies have shown the involvement of the right temporoparietal junction (TPJ) in resolving a dilemma through cooperation, a causal relationship between the two has rarely been explored. …”
Get full text

إدارة الأزمة ومكونات المنظمة - دراسة حالة في واقعة الطف by علي عبد الحسين الفضل, غسان رشاد دوش

“…The highlights of the research objectives were: 1. highlight the role for some administrative groups that formed in the light of the behind-Husseini and the reference to the most important roles and functions entrusted to each group. 2. Determine the role of coherent components of the organization, which has led to a typical overcome the crisis, which hinder the achievement of important objectives. …”
Get full text

Effectiveness of case-area targeted interventions including vaccination on the control of epidemic cholera: protocol for a prospective observational study by Lauren D'Mello-Guyett, Ruwan Ratnayake, Andrew S Azman, Yap Boum, Francesco Checchi, W John Edmunds, Placide Okitayemba Welo, Nicolas Peyraud, Iza Ciglenecki, Etienne Gignoux, Maria Lightowler, Primitive Gakima, Jean Patrick Ouamba, Joseph Amadomon Sagara, Rollin Ndombe, Nana Mimbu, Alexandra Ascorra, Elisabeth Mukamba Musenga, Berthe Miwanda, Francisco Luquero, Klaudia Porten, Flavio Finger, Miriam Alia, Bachir Assao, Catherine Bachy, Rob D'hondt, Karl Njuwa Fai, Caroline Henry-Ostian, Abdoul-Moumouni Issa-Soumana, Danish Malik, Herbert Mutubuki, Rodrigue Ntone, Isabella Panunzi, Issaka Soumana, Oumar Touré, Mamady Traore

“…We will compare the cumulative incidence among rings as a function of response delay, as a proxy for performance. …”
Get full text

Diagnostic significance of TGF-β1 in kidney recipients with graft dysfunction by О. P. Shevchenko, S. О. Sharapchenko, D. A. Velikiy, О. Е. Gichkun, E. S. Stolyarevich, N. P. Mozheiko, D. A. Saydulaev, R. М. Kurabekova, E. A. Vakurova, A. A. Mamedova, M. A. Osoblivaya

“…Kidney recipients included 95 patients with laboratory and clinical signs of graft dysfunction, who underwent biopsy of the transplanted kidney, followed by morphological examination, and 34 recipients with normal graft function. Serum TGF-β1 levels in the kidney recipients were significantly higher than in their healthy counterparts (p = 0.00001); it did not correlate with most blood test parameters; with the glomerular filtration rate (GFR). …”
Get full text

Antithrombotic Therapy in Patients with Malignant Lymphoproliferative Disorders Treated with Ibrutinib by EI Emelina, GE Gendlin, IG Nikitin

“…The use of ibrutinib influencing the platelet function constitutes an additional bleeding risk. A crucial task consists in risk minimization of both hemorrhagic complications and thrombosis while sticking to ibrutinib treatment. …”
Get full text

Unmanned trackless rubber wheeler based on LD improved Cartographer mapping algorithm underground SLAM autonomous navigation method and test by Fangwei LI, Jiusheng BAO, Chen WANG, Xiaoming YUAN, Yan YIN, Shirong GE, Maosen WANG, Yuhan LV

“…In addition, the local path planning is carried out by TEB algorithm to realize the obstacle avoidance function in the real-time environment of unmanned trackless rubber wheeler. …”
Get full text

Construction and validation of frailty risk prediction model in elderly patients with colorectal cancer by Yuxiao Xia, Mengzhang He, Yiqun Guo, Fenghua Zhang, Xiongting Wu, Rong Chen, Linli Duan, Fang Chen, Xuewei Yang, Xiuli Feng

“…Conclusion Age, comorbidity, sleep quality, anxiety, and cognitive function were identified as independent predictors of frailty in elderly colorectal cancer patients. …”
Get full text

Comparative effectiveness of different transarterial embolization therapies alone or in combination with local ablative or adjuvant systemic treatments for unresectable hepatocellu... by Konstantinos Katsanos, Panagiotis Kitrou, Stavros Spiliopoulos, Ioannis Maroulis, Theodore Petsas, Dimitris Karnabatidis

“…All analyses complied with the ISPOR-AMCP-NCP Task Force Report for good practice in NMA.<h4>Findings</h4>The network of evidence included 55 RCTs (12 direct comparisons) with 5,763 patients with preserved liver function and unresectable HCC (intermediate to advanced stage). …”
Get full text

A COMPARATIVE ANALYSIS OF THE ASSORTMENT OF DIFFERENT MEDICATION GROUPS USED IN THE CENTRAL REGIONAL HOSPITAL OF THE MUNICIPAL REGION AND THE REGIONAL HOSPITAL OF THE FEDERAL STATE... by B. G. Bochkarev, I. V. Kalinin, T. I. Kabakova

“…Providing quality pharmaceutical care is a key task of healthcare; any medical organization must respond efficiently to a change in both external and internal factors that affect the medical support of patients. …”
Get full text

Adaptive Model Predictive Control for 4WD-4WS Mobile Robot: A Multivariate Gaussian Mixture Model-Ant Colony Optimization for Robust Trajectory Tracking and Obstacle Avoidance by Hayat Ait Dahmad, Hassan Ayad, Alfonso García Cerezo, Hajar Mousannif

“…Trajectory tracking is a crucial task for autonomous mobile robots, requiring smooth and safe execution in dynamic environments. …”
Get full text

Attentional dysfunction arises from right frontocentral and occipital network connectivity in Parkinson's disease by Isobel Timothea French, Kuo-Hsuan Chang, Wei-Kuang Liang, Wen-Sheng Chang, Yen-Shi Lo, Yi-Ru Wang, Mei-Ling Cheng, Norden E. Huang, Hsiu-Chuan Wu, Siew-Na Lim, Chiung-Mei Chen, Chi-Hung Juan

“…Conclusions: These visuospatial attention deficits of PD revealed with the advanced analytical method of the HHSA and HHCFPC may inaugurate further neurophysiological biomarkers for cognitive function evaluation in PD and related movement disorders.…”
Get full text

A designed predictive modelling strategy based on data decomposition and machine learning to forecast solar radiation by Mumtaz Ali, Ramendra Prasad, Salman Alamery, Aitazaz Ahsan Farooque

“…Subsequently, the statistically significant lagged subseries at a week ahead forecasting horizon (t – 1) of the low-frequency PFs with residual components are extracted individually, via partial autocorrelation function (PACF), to capture the historical behaviour of frequency-resolved SR component in order to build a robust modelling framework. …”
Get full text

Harnessing deep learning to detect bronchiolitis obliterans syndrome from chest CT by Mateusz Koziński, Doruk Oner, Jakub Gwizdała, Catherine Beigelman-Aubry, Pascal Fua, Angela Koutsokera, Alessio Casutt, Argyro Vraka, Michele De Palma, John-David Aubert, Horst Bischof, Christophe von Garnier, Sahand Jamal Rahi, Martin Urschler, Nahal Mansouri

“…Abstract Background Bronchiolitis Obliterans Syndrome (BOS), a fibrotic airway disease that may develop after lung transplantation, conventionally relies on pulmonary function tests (PFTs) for diagnosis due to limitations of CT imaging. …”
Get full text

Gut microbiome features in pediatric food allergy: a scoping review by Margherita Farnetano, Laura Carucci, Laura Carucci, Serena Coppola, Serena Coppola, Franca Oglio, Franca Oglio, Antonio Masino, Antonio Masino, Marica Cozzolino, Marica Cozzolino, Rita Nocerino, Rita Nocerino, Rita Nocerino, Roberto Berni Canani, Roberto Berni Canani, Roberto Berni Canani, Roberto Berni Canani

Get full text

Guidelines for the clinical application of the Xihuang pill for the prevention and treatment of breast hyperplasia diseases by Hongmei Tang, Qin Lu, Shiyin Feng, Zhiwei Xiao, Wanyin Wu, Gaofeng Chen, Li Deng, Tianqi Yu, Junyan Wu, Hua Lin, Bo Ji, Jietao Lin, Chengguang Zhang, Liming Li, Tao Liu, Yong Ouyang, Kaijun Lei, Jun Chen, Weiwen Peng, Zhenwen Qiu, Qingqun Cai, Qi Liang, Cuiling Liu, Yuzhen Li, Lixia Zhu, Zexin Zhang, Xueting Liu, Lizhu Lin, Zhihua Zheng

“…Safety indicators, including blood analysis and liver and kidney function monitoring, should be performed regularly during treatment.Conclusions Current clinical evidence suggests that XHP can be used as a standalone treatment or in conjunction with other medications to prevent and manage breast hyperplasia diseases. …”
Get full text