A Combinatorial Functional Precision Medicine Platform for Rapid Therapeutic Response Prediction in AML by Noor Rashidha Binte Meera Sahib, Jameelah Sheik Mohamed, Masturah Bte Mohd Abdul Rashid, Jayalakshmi, Yihao Clement Lin, Yen Lin Chee, Bingwen Eugene Fan, Sanjay De Mel, Melissa Gaik Ming Ooi, Wei‐Ying Jen, Edward Kai‐Hua Chow

“…ABSTRACT Background Despite advances made in targeted biomarker‐based therapy for acute myeloid leukemia (AML) treatment, remission is often short and followed by relapse and acquired resistance. Functional precision medicine (FPM) efforts have been shown to improve therapy selection guidance by incorporating comprehensive biological data to tailor individual treatment. …”
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Estimation for spatial semi-functional partial linear regression model with missing response at random by Benchikh Tawfik, Almanjahie Ibrahim M., Fetitah Omar, Attouch Mohammed Kadi

“…The aim of this article is to study a semi-functional partial linear regression model (SFPLR) for spatial data with responses missing at random (MAR). …”
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Stress Response of Aspergillus niger Spores to Copper Surfaces and the Implications for Antifungal Surface Functionalization by Stella Marie Timofeev, Katharina Siems, Daniel Wyn Müller, Aisha Saddiqa Ahmed, Alessa Schiele, Kristina Brix, Carolin Luisa Krämer, Franca Arndt, Ralf Kautenburger, Frank Mücklich, Stefan Leuko

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Computational modeling of the relationship between morphological heterogeneity and functional responses in mouse hippocampal astrocytes by Anna Freund, Alexander Mayr, Peter Winkler, Rene Weber, Aapo Tervonen, Ron Refaeli, Kerstin Lenk, Kerstin Lenk

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Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response. by Monica Sueiro-Olivares, Jennifer Scott, Sara Gago, Dunja Petrovic, Emilia Kouroussis, Jasmina Zivanovic, Yidong Yu, Marlene Strobel, Cristina Cunha, Darren Thomson, Rachael Fortune-Grant, Sina Thusek, Paul Bowyer, Andreas Beilhack, Agostinho Carvalho, Elaine Bignell, Milos R Filipovic, Jorge Amich

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Evaluation of clopidogrel responsiveness using the Platelet Function Analyzer-200 (PFA-200) in dogs by Joon-Ho Shin, Hyun-Jung Han, Hyun-Jung Han

“…We aimed to evaluate the prevalence of clopidogrel resistance in hypercoagulable dogs using the Platelet Function Analyzer-200 (PFA-200) P2Y cartridge; further, we aimed to assess the utility of hematocrit (HCT), platelet count (PLT), prothrombin time (PT), activated partial thromboplastin time (aPTT), thromboelastography (TEG) parameters, and D-dimer level as indicators of clopidogrel efficacy. …”
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Identification and Preliminary Functional Analysis of Responsive Genes to Short-term Heat Stress in Lettuce by Shuping He, Guotao Huo, Guojun Ge, Li Du, Du Long, Lijun Luo, Ping Long, Shiwei Wei

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Identification and functional analysis of light-responsive unique genes and gene family members in rice. by Ki-Hong Jung, Jinwon Lee, Chris Dardick, Young-Su Seo, Peijian Cao, Patrick Canlas, Jirapa Phetsom, Xia Xu, Shu Ouyang, Kyungsook An, Yun-Ja Cho, Geun-Cheol Lee, Yoosook Lee, Gynheung An, Pamela C Ronald

“…This list was further refined by mining gene expression data to exclude genes that had potential functional redundancy due to co-expressed family members (12 genes) and genes that had inconsistent light responses across other publicly available microarray datasets (five genes). …”
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Heart Failure Impairs Bone Marrow Hematopoietic Stem Cell Function and Responses to Injury by Tina B. Marvasti, Faisal J. Alibhai, Grace J. Yang, Shu‐Hong Li, Jun Wu, Terrence Yau, Ren‐Ke Li

“…Conclusions HF alters the BM composition, adversely affects cell reconstitution potential, and alters cellular responses to injury. Further studies are needed to determine whether restoring BM function can impact disease progression or improve cellular responses to injury.…”
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Linking the neural signature of response time variability to Alzheimer’s disease pathology and cognitive functioning

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Function of eEF-1γ in the nucleus in response to insulin in hepatocellular carcinoma cells by Abu Jubayer Hossain, Amir Hamza, Rokibul Islam, Oyungerel Dogsom, Jae-Bong Park

“…Chromatin immunoprecipitation PCR (ChIP-PCR) confirmed eEF-1γ association with RBP4 promoter. Functionally, si-eEF-1γ reduced cell proliferation and deceased c-Myc and cyclin D1 protein levels. …”
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A Diseased Three-Species Harvesting Food Web Model with Various Response Functions by Thangavel Megala, Thangaraj Nandha Gopal, Manickasundaram Siva Pradeep, Arunachalam Yasotha

“…The Crowley–Martin and Beddington–DeAngelis functional responses are used by predators to consume both susceptible and infected prey. …”
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Dynamics of a Stochastic SIRS Epidemic Model with Regime Switching and Specific Functional Response by Amine EL Koufi, Abdelkrim Bennar, Noura Yousfi

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Response to Training in Emotion Recognition Function for Mild TBI/PTSD Survivors: Pilot Study by J. Kay Waid-Ebbs, Kristen Lewandowski, Yi Zhang, Samantha Graham, Janis J. Daly

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Breadth and function of antibody response to acute SARS-CoV-2 infection in humans. by Kuan-Ying A Huang, Tiong Kit Tan, Ting-Hua Chen, Chung-Guei Huang, Ruth Harvey, Saira Hussain, Cheng-Pin Chen, Adam Harding, Javier Gilbert-Jaramillo, Xu Liu, Michael Knight, Lisa Schimanski, Shin-Ru Shih, Yi-Chun Lin, Chien-Yu Cheng, Shu-Hsing Cheng, Yhu-Chering Huang, Tzou-Yien Lin, Jia-Tsrong Jan, Che Ma, William James, Rodney S Daniels, John W McCauley, Pramila Rijal, Alain R Townsend

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Impact of prey species, host plant, and predator sex on the functional response of Orius strigicollis by Yi-Ting Hung, Cheng-Kang Tang, Yi-Ting Chung, Wei-Han Lai, Han-Yan Ding, Ali Güncan, Pavel Saska, Shu-Jen Tuan

“…O. strigicollis consistently exhibited a Type II functional response when fed on both of thrip larvae and spider mites on eggplant and runner bean. …”
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Different functional responses in populations of Polylepis quadrijuga (Rosaceae) as a consequence of anthropogenic disturbance by Yessica D. Hoyos, Natalia Vargas, Adriana Sanchez

“…Despite their role in regulating water flow and forming biodiverse, endemic biotic communities, there are few studies on their functional responses to stress caused by anthropogenic disturbance and climate change. …”
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Fault diagnosis of nonlinear analog circuits using generalized frequency response function and LSSVM by Jialiang Zhang, Yaowang Yang

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A novel GMMA-based gonococcal vaccine demonstrates functional immune responses in mice by Marco Spinsanti, Elisabetta Monaci, Giacomo Romagnoli, Giada Buffi, Andrea Guido Oreste Manetti, Filippo Carboni, Giovanna Tuscano, Lucia Eleonora Fontana, Sara Tomei, Marta Zambelli, Rossella Cuffaro, Marianna Taccone, Chiara Sammicheli, Claudia Gianfaldoni, Francesca Angiolini, Maria Giuliani, Sara Marchi, Silvia Senesi, Christian Matano, Ivan Pisoni, Nathalie Norais, Maria Rosaria Romano, Silvia Rossi Paccani, Silvana Savino, Alessandro Muzzi, Federico Fontani, Davide Serruto, Michela Brazzoli, Giulia Giordano, Monica Fabbrini, Ugo D’Oro, Oretta Finco, Immaculada Margarit, Isabel Delany, Erika Bartolini

“…NgG induced a robust immune response in mice and outperformed the comparator vaccine 4CMenB in several serological and functional tests. …”
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The relationship of systemic inflammatory response with structural and functional changes in the myocardium in patients with pulmonary tuberculosis by D. V. Kolchin, V. I. Ruzov, L. N. Savonenkova, V. A. Razin

“…There is no direct relationship between the severity of the systemic inflammatory response and structural and functional changes in the heart.…”
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