Variants in Neurotransmitter-Related Genes Are Associated with Alzheimer’s Disease Risk and Cognitive Functioning but Not Short-Term Treatment Response by Tirso Zúñiga-Santamaría, Blanca Estela Pérez-Aldana, Ingrid Fricke-Galindo, Margarita González-González, Zoila Gloria Trujillo-de los Santos, Marie Catherine Boll-Woehrlen, Rosalía Rodríguez-García, Marisol López-López, Petra Yescas-Gómez

“…<i>BCHE</i> rs1803274 was associated with worse cognitive functioning. None of the genetic and non-genetic factors studied were associated with the response to pharmacological treatment. …”
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Characterization of Prejunctional Muscarinic Receptors: Effects on the Release of VIP and Functional Responses and Receptor Expression in the Ovine Submandibular Gland by Anders T. Ryberg, Ondrej Soukup, Gunnar Tobin

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Functional Relationships Reveal Large Differences in Streamflow Response to eCO2‐Vegetation in Global Water Models by Haoshan Wei, Yongqiang Zhang, Qi Huang, Changming Liu, Thorsten Wagener

“…To study these differences, we compared model outputs against observations from 1,116 small, unimpacted catchments. Functional relationships between climate variables, such as precipitation (P), aridity, and temperature (T), and eCO2‐vegetation‐driven streamflow (QCO2) changes show large deviations between models and observations, especially in response to changing leaf area index (LAI). …”
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Effects of Rumen-Protected Taurine Supplementation on Ruminal Fermentation, Hematological Profiles, Liver Function, and Immune Responses in Yaks by Shoupei Zhao, Lianghao Lu, Yuanyuan Chen, Huaming Yang, Bao Zhang, Mingyu Cao, Wenju Chao, Wanchao Xue, Xiaorong Fan, Jianxin Xiao, Rui Hu, Quanhui Peng, Lizhi Wang, Zhisheng Wang, Bai Xue

“…The present study evaluated the effects of dietary rumen-protected taurine (RPT) supplementation on ruminal fermentation, hematological parameters, liver function, stress-related hormones, and immune responses in yaks. …”
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Gut response to the dietary supplementation with sodium butyrate in broiler chickens: morphology and microbiota composition and predictive functional groups by Giulia Zardinoni, Almudena Huerta, Marija Boskovic Cabrol, Angela Trocino, Elisa Fonsatti, Cristina Ballarin, Martina Bortoletti, Marco Birolo, Francesco Bordignon, Piergiorgio Stevanato, Daniel Julian, Gerolamo Xiccato

“…This study investigated the effects of Na-butyrate supplementation (0 vs. 150 vs. 300 mg/kg) and the dietary fat level (7.7% vs. 6.7% in the grower diet; 8.9% vs. 7.7% in the finisher diet) in 900 broiler chickens of both sexes, out of which 108 were used to evaluate gut morphology and immune response on jejunum tissues at 14, 28, and 40 days of age, and caecal microbiota composition according to 16S rRNA gene multi-amplicon sequencing and the predictive functional bacteria groups at 40 d of age. …”
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Prediction of Head Injury Criteria in Pedestrian Crashes Using Frequency Response Function-Based Deep Neural Networks by Seon-Hong Kim, Seounghyun Lee, Taewung Kim, Je-Heon Han

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Complement mediated signaling on pulmonary CD103(+) dendritic cells is critical for their migratory function in response to influenza infection. by Matheswaran Kandasamy, Poon C Ying, Adrian W S Ho, Hermi R Sumatoh, Andreas Schlitzer, Timothy R Hughes, David M Kemeny, B Paul Morgan, Florent Ginhoux, Baalasubramanian Sivasankar

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Gut microbiota‐CRAMP axis shapes intestinal barrier function and immune responses in dietary gluten‐induced enteropathy by Zhengnan Ren, Li‐Long Pan, Yiwen Huang, Hongbing Chen, Yu Liu, He Liu, Xing Tu, Yanyan Liu, Binbin Li, Xiaoliang Dong, Xiaohua Pan, Hanfei Li, Yu V Fu, Birgitta Agerberth, Julien Diana, Jia Sun

“…These results highlight microbiota‐CRAMP axis in the modulation of barrier function and immune responses in GIE. Hence, modulating CRAMP may represent a therapeutic strategy for celiac disease.…”
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Response of Soil Microbial Diversity, Community Structure, and Functional Potential to Primary Forest Conversion in Northwestern Hunan Province by XIAO Huacui, SHENG Hao, SU Guohui, ZHOU Ping

“…[Results] Comparing to the primary forest, the bacterial diversity was increased by 29%—34% in cultivated lands, while the fungal diversity was decreased by 42%—49% in the orchards. The response direction and magnitude of soil bacterial and fungal predicted function depended on the specific soil function and converted land-use type. …”
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Phyllosphere Bacterial Communities in Wheat and Faba Bean Intercropping: Structural and Functional Mechanisms in Response to Stripe Rust Infection by Lili Mao, Pranita Mhaske, Jingxiu Xiao, Li Tang, Ling Qian, Yi Zheng

“…Although evidence suggests that intercropping enhances nutrient efficiency and recruits beneficial bacteria at the root-soil interface, limited research has explored changes in the phyllosphere microbiome in response to foliar diseases. Pot experiments were conducted to investigate how wheat stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), affects shoot biomass, total nitrogen, and total potassium content; changes of phyllosphere bacteria; co-occurrence networks; and ecological functions in wheat and faba bean intercropping using 16S amplicon sequencing. …”
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Correction: Identification of SRS transcription factor family in Solanum lycopersicum, and functional characterization of their responses to hormones and abiotic stresses by Wang Lu, Yan Wang, Yuan Shi, Qin Liang, Xiangyin Lu, Deding Su, Xin Xu, Julien Pirrello, Ying Gao, Baowen Huang, Zhengguo Li

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Positive Steady States of a Strongly Coupled Predator-Prey System with Holling-(n+1) Functional Response by Xiao-zhou Feng, Zhi-guo Wang

“…This paper discusses a predator-prey system with Holling-(n+1) functional response and the fractional type nonlinear diffusion term in a bounded domain under homogeneous Neumann boundary condition. …”
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A single transcription factor regulates evolutionarily diverse but functionally linked metabolic pathways in response to nutrient availability by Amy K Schmid, David J Reiss, Min Pan, Tie Koide, Nitin S Baliga

“…Here, we demonstrate that a single TrmB family transcription factor in Halobacterium salinarum NRC‐1 globally coordinates functionally linked enzymes of diverse phylogeny in response to changes in carbon source availability. …”
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Analytical strength-duration curve for the spiking response of the LIF neuron to an alpha-function-shaped excitatory current pulse by Alexander Paraskevov

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Dynamic Analysis of a Delayed Reaction-Diffusion Predator-Prey System with Modified Holling-Tanner Functional Response by Xinhong Pan, Min Zhao, Chuanjun Dai, Yapei Wang

“…A predator-prey model with modified Holling-Tanner functional response and time delays is considered. By regarding the delays as bifurcation parameters, the local and global asymptotic stability of the positive equilibrium are investigated. …”
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Changing grizzly bear space use and functional connectivity in response to human disturbance in the southern Canadian Rocky Mountains by Eric C. Palm, Clayton D. Apps, Tal Avgar, Melanie Dickie, Bruce N. McLellan, Joseph M. Northrup, Michael A. Sawaya, Julie W. Turner, Jesse Whittington, Erin L. Landguth, Katherine A. Zeller, Clayton T. Lamb

“…Our study builds upon existing work simulating animal space use from fitted iSSFs by incorporating individual‐level variation into population‐level simulations and by fitting functional responses that help capture broad‐scale variation in behavior and improve model transferability to new areas. …”
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Association of item‐level responses to cognitive function index with tau pathology and hippocampal volume in the A4 Study by Idris Demirsoy, Elham Ghanbarian, Babak Khorsand, Bhargav T. Nallapu, Kellen K. Petersen, Richard B. Lipton, S. Ahmad Sajjadi, Laura A. Rabin, Ali Ezzati

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White matter properties in fronto-parietal tracts predict maladaptive functional activation and deficient response inhibition in ADHD by Daniel Smullen, Andrew P. Bagshaw, Lilach Shalev, Shlomit Tsafrir, Tamar Kolodny, Carmel Mevorach

“…Recently, it has been suggested that a specific fronto-parietal functional circuitry between the inferior frontal gyrus (IFG) and the intraparietal sulcus (IPS), dictates the recruitment of the IPS during response inhibition in ADHD. …”
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Real-World Data on Morphological and Functional Responses After Switching to Faricimab in Recalcitrant, Chronic Diabetic Macular Edema by Viktoria Deiters, Anna Lorger, Franziska Eckardt, Jakob Siedlecki, Benedikt Schworm, Siegfried G. Priglinger, Tina R. Herold

“…Abstract Introduction This study aimed to assess the morphological and functional effects of faricimab in patients with chronic diabetic macular edema (DME) who had an insufficient response to previous treatments. …”
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Exploring the functional diversity and metabolic activities of the human gut microbiome in Thai adults in response to a prebiotic diet by Amornthep Kingkaw, Preecha Patumcharoenpol, Narissara Suratannon, Massalin Nakphaichit, Sittiruk Roytrakul, Wanwipa Vongsangnak

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