APOLLO-Live: A multi-criteria-based webtool for synchronous group decision making and consensus support in energy and climate policy deliberations [version 2; peer review: 1 approv... by Anastasios Soursos, Konstantinos Koasidis, Álvaro Labella, Georgios Xexakis, Alexandros Nikas, Anastasios Karamaneas

“…We highlight the functionalities of the webtool, including how it can be used to advance stakeholder dialogues, in two use cases targeting the preferences of the youth in terms of (a) actions to advance climate action and (b) investments to be prioritised. …”
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Identification, Detection, and Management of Soft Rot Disease of Ginger in the Eastern Himalayan Region of India by Utpal Dey, Shatabhisa Sarkar, Durga Prasad Awasthi, Mukesh Sehgal, Ravinder Kumar, Biman De, Nayan K. Adhikary, Abhijit Debnath, Rahul Kumar Tiwari, Milan Kumar Lal, Subhash Chander, Ph. Ranjit Sharma, Amulya Kumar Mohanty

“…BCAs can suppress the phytopathogenic fungi and modulate different functions in plants.…”
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EDEN: Exploring Disks Embedded in N-body Simulations of Milky Way–mass Halos from Symphony by Yunchong Wang, Philip Mansfield, Ethan O. Nadler, Elise Darragh-Ford, Risa H. Wechsler, Daneng Yang, Hai-Bo Yu

“…We find that disks near the median disk-to-halo mass ratio of our sample ( M _*,Disk / M _vir,host  = 2%) reduce subhalo peak mass functions within 100 kpc by about 10% for peak masses above 10 ^8 M _⊙ . …”
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Insights Into Cryoconite Community Dynamics on the Alpine Glacier Throughout the Ablation Season by Tereza Novotná Jaroměřská, Roberto Ambrosini, Dorota Richter, Miroslawa Pietryka, Przemyslaw Niedzielski, Juliana Souza‐Kasprzyk, Piotr Klimaszyk, Andrea Franzetti, Francesca Pittino, Lenka Vondrovicová, Antonella Senese, Krzysztof Zawierucha

“…However, the lack of seasonal observations of cryoconite biota limits our knowledge of glacial ecosystem functioning. We studied photoautotrophs, consumers and sediment characteristics (community structure, biomass, elemental composition, organic matter content, δ13C, δ15N) from cryoconite holes in the upper and lower parts of the Forni Glacier ablation zone (Italy) throughout the ablation season. …”
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The N‐terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism by Xue Wang, Chunyou Ning, Xingyi Cheng, Zhengzhong Wu, Dongbo Wu, Xuemei Ding, Cunxiang Ju, Zhihang Zhou, Lingfeng Wan, Wei Zhao, Peiliang Shi

“…We analyzed differentially expressed genes by RNA sequencing and explored their biological functions. The efficacy of obeticholic acid (OCA) in the treatment of liver fibrosis was assessed. …”
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What patients with lung cancer with comorbidity tell us about interprofessional collaborative care across healthcare sectors: qualitative interview study by Michel Wensing, Johanna Forstner, Michael Thomas, Jasmin Bossert, Matthias Villalobos, Anja Siegle, Corinna Jung, Nicole Deis, Katja Krug

“…All data were managed and organised in MAXQDA.Results In 15 interviews, participants reported that cross-sectoral collaboration functioned well, if treatments occurred as planned. …”
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Radial Profiles of Σ*, ΣSFR, Gas Metallicity, and Their Correlations across the Galactic Mass–Size Plane by Lin Lin, Shiyin Shen, Hassen M. Yesuf, Ye-Wei Mao, Lei Hao

“…Radial profiles of stellar mass surface density (Σ _* ) and star formation rate surface density (Σ _SFR ) as functions of the effective radius ( R / R _e ) reveal that compact galaxies display steeper gradients and higher values, resulting in elevated specific star formation rates (sSFRs) in their inner regions compared to their outskirts. …”
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A model for the cognitive assessment of physicians by Victor A. Del Bene, Victor A. Del Bene, George Howard, David S. Geldmacher, Elizabeth Turnipseed, Catherine Brown, Catherine Brown, Kathleen Lowry, Trevor Starling, Kate Bryan, T. Charles Fry, Keith A. Jones, Keith A. Jones, Keith A. Jones, Ronald M. Lazar, Ronald M. Lazar

“…Existing age-corrected methods from the general population can potentially mask cognitive impairment in medical professionals.…”
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Proactive and reactive movement behaviours shape the antipredator sequence in a large herbivore by Charlotte Vanderlocht, Benjamin Robira, Andrea Corradini, Simone Dal Farra, Federico Ossi, Davide Righetti, Heidi C. Hauffe, Luca Pedrotti, Francesca Cagnacci

“…Using an exhaustive inventory of red deer hunting events and very high-resolution canopy cover density (LiDAR), we combined movement metric (displacement and path length) models and integrated step selection functions to investigate antipredator movement responses to lethal risk on various spatiotemporal scales, considering a dynamic landscape of risk. …”
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APOLLO-Live: A multi-criteria-based webtool for synchronous group decision making and consensus support in energy and climate policy deliberations [version 3; peer review: 1 approv... by Anastasios Soursos, Konstantinos Koasidis, Álvaro Labella, Georgios Xexakis, Alexandros Nikas, Anastasios Karamaneas

“…We highlight the functionalities of the webtool, including how it can be used to advance stakeholder dialogues, in two pilot use cases targeting the preferences of the youth in terms of (a) actions to advance climate action and (b) investments to be prioritised. …”
Get full text

Deep brain stimulation-entrained gamma oscillations in chronic home recordings in Parkinson's disease by Maria Olaru, Amelia Hahn, Maria Shcherbakova, Simon Little, Wolf-Julian Neumann, Reza Abbasi-Asl, Philip A. Starr

“…Conclusion: Stimulation-entrained gamma oscillations are functionally and physiologically distinct from levodopa-induced gamma oscillations that occur in the absence of deep brain stimulation. …”
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Unveiling the heightened susceptibility: Exploring early hypophosphatemia in critically ill trauma patients by Chi-Ju Yang, Chia-Ming Chang, Gyu-Ping Chang, Huei-Ting Tsai, Ting-Yu Yu, Yin-Yi Han

“…Background: Phosphorus is a vital mineral crucial for various physiological functions. Critically ill trauma patients frequently experience hypophosphatemia during the immediate post-traumatic phase, potentially impacting outcomes. …”
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Stimulus-responsive biomaterials for Helicobacter pylori eradication by Tiantian Shan, Xi Chen, Xinxuan Zhou, Nanxi Wang, Biao Ren, Lei Cheng

“…Stimulus-responsive biomaterials can respond to chemical, biological or physical cues in the environment with corresponding changes in their own properties and functions, highlighting a more intelligent, targeting and efficient aspect for H. pylori therapy.Aim of Review: This review describes the critical obstacles in the current treatment of H. pylori, summarizes the recent advances in stimulus-responsive biomaterials against H. pylori by elucidating their working mechanisms and antibacterial performances under different types of stimuli (pH, enzymes, light, magnetic and ultrasound irradiations), and attempts to analyze the future prospects of such smart biomaterial for H. pylori eradication.Key Scientific Concepts of Review: Any characteristic property or change in the biomilieu at the H. pylori infected site (endogenous stimuli) or specific iatrogenic conditions in vitro (exogenous stimuli) can act as cues to activate or potentiate the antibacterial activity of responsive biomaterials. …”
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GFAPβ and GFAPδ Isoforms Expression in Mesenchymal Stem Cells, MSCs Differentiated Towards Schwann-like, and Olfactory Ensheathing Cells by Nidia Jannette Carrillo González, Gabriela Stefania Reyes Gutierrez, Tania Campos-Ordoñez, Rubén D. Castro-Torres, Carlos Beas Zárate, Graciela Gudiño-Cabrera

“…These cells express the Glial fibrillary acidic protein (GFAP), a type of cytoskeletal protein that significantly regulates many cellular functions, including those that promote cellular plasticity needed for regeneration. …”
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Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study. by Darren M Lipnicki, John D Crawford, Rajib Dutta, Anbupalam Thalamuthu, Nicole A Kochan, Gavin Andrews, M Fernanda Lima-Costa, Erico Castro-Costa, Carol Brayne, Fiona E Matthews, Blossom C M Stephan, Richard B Lipton, Mindy J Katz, Karen Ritchie, Jacqueline Scali, Marie-Laure Ancelin, Nikolaos Scarmeas, Mary Yannakoulia, Efthimios Dardiotis, Linda C W Lam, Candy H Y Wong, Ada W T Fung, Antonio Guaita, Roberta Vaccaro, Annalisa Davin, Ki Woong Kim, Ji Won Han, Tae Hui Kim, Kaarin J Anstey, Nicolas Cherbuin, Peter Butterworth, Marcia Scazufca, Shuzo Kumagai, Sanmei Chen, Kenji Narazaki, Tze Pin Ng, Qi Gao, Simone Reppermund, Henry Brodaty, Antonio Lobo, Raúl Lopez-Anton, Javier Santabárbara, Perminder S Sachdev, Cohort Studies of Memory in an International Consortium (COSMIC)

“…<h4>Background</h4>The prevalence of dementia varies around the world, potentially contributed to by international differences in rates of age-related cognitive decline. …”
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Humic acids as drivers of plant growth: regulating root development and photobiology through redox modulation by Daniel Basílio Zandonadi, Hiarhi Monda, Jason Gralian, Aletia James, Richard T. Lamar, Mirella Pupo Santos

“…These effects may be attributed to the interplay between the pro-oxidant (e.g., quinones and semiquinone radicals) and the antioxidant functionalities (e.g., polyphenols) inherent in HA, both contributing to the observed eustress response. …”
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Synthesis of 5-Fluorouracil (5-FU) coated platinum nanoparticles and apoptotic effects on U87 human glioblastoma cells by Atena Abed, Merat Karimi, Majid Nejati, Michael R. Hamblin, Seyed Abbas Mirzaei, Mostafa Sarvizadeh, Hamed Mirzaei

“…Conclusion PtNPs effectively functioned as a delivery platform for 5-FU, improving its release kinetics and promoting apoptotic responses while potentially minimizing systemic toxicity. …”
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Assessment of the TGF-β gene and its target miR-1908-5p gene expression and its role in the treatment of beta-thalassemia in Iraqi patients by Manal Lafta Abdulhassn, Hiba Muneer Abdel Hassan Al-Khafaji, Maryam Qasim Mohammed

“…BACKGROUND: Thalassemia is potentially inherited fatal anemia and can cause health problems when left untreated. …”
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235 Root cause analysis of barriers and facilitators to accrual to a pragmatic, EHR-embedded clinical trial by Lindsay Lennox, Bethany M Kwan, Adit A Ginde, Thomas W. Flaig, Sarah V Kautz, Matthew Mimnall, Andrew Nicklwsky, Goldie Komaie, Christine Velez, Aaron Babour, Laurie Blmberg-Romero, Cecilia C. Low Wang

“…Discussion/Significance of Impact: While pragmatic EHR-embedded trials are often characterized as lower-burden, these trials still require active engagement by providers, as well as ongoing attention from both research and informatics teams to ensure that EHR-embedded processes are functioning as designed, and that they are effective in recruiting study participants.…”
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Barleria extracts containing barlerin and verbascoside boost immunity and regulate CYP450 gene in prostate cancer by Sanit Kaewdaungdee, Zi Wei Sham, Hao Xuan Ho, Shiou Yih Lee, Tawatchai Tanee, Yannick D. Benoit, Thomas Liehr, Sakda Daduang, Runglawan Sudmoon, Arunrat Chaveerach

“…This study provides a comprehensive analysis of six Barleria leaf extracts, namely B. cristata, B. lupulina, B. prionitis, B. repens, B. siamensis, and B. strigosa, to elucidate their metabolite composition, toxicity, immunomodulatory functions, and roles in cytochrome P450 (CYP) gene expression. …”
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