Blueberry Attenuates Liver Fibrosis, Protects Intestinal Epithelial Barrier, and Maintains Gut Microbiota Homeostasis by Zhiqiang Yan, Fang Yang, Zhu Hong, Shishun Wang, Zhang Jinjuan, Bing Han, Rujia Xie, Feiyun Leng, Qin Yang

“…The liver weight and body weight were measured, the liver function was monitored by ALT and AST activity, protein and mRNA were determined by western blot and RT-qPCR, and the gut microbiome was detected by Miseq. …”
Get full text

Development and validation of a machine learning model based on multiple kernel for predicting the recurrence risk of Budd-Chiari syndrome by Weirong Xue, Bing Xu, Hui Wang, Xiaoxiao Zhu, Jiajia Qin, Guangshuang Zhou, Peilin Yu, Shengli Li, Yingliang Jin

“…The test set was used to compare kernel function combinations, with the area under the curve (AUC), sensitivity, specificity, and accuracy as evaluation metrics. …”
Get full text

Feasibility study of a novel wireless localization technique using radiofrequency identification markers for small and deeply located lung lesionsCentral MessagePerspective by Yojiro Yutaka, MD, PhD, Toshihiko Sato, MD, PhD, Satona Tanaka, MD, PhD, So Miyahara, MD, PhD, Akihiro Yoshizawa, MD, PhD, Satoshi Morita, MD, PhD, Hiroshi Date, MD, PhD

“…Objectives: To evaluate the safety and efficacy of a novel wireless localization technique that uses radiofrequency identification markers for small and deep lung lesions. …”
Get full text

Mechanisms of adaptation to intensive loads of 400 meters’ hurdles runners at stage of initial basic training by A.S. Rovniy, V.M. Lastochkin

“…It was shown that for determination of functional potentials for such kind of functioning it is necessary to apply special loads. …”
Get full text

Genomic signal selection analysis reveals genes related to the lambing trait of Hotan sheep by XinKun Wang, Wei Li, QiaoYan Huang, HuiPing Sun, LeXiao Zhu, RuoHuai Gu, Feng Xing

“…We identified 290 selected regions and 332 genes across the Hotan sheep genome by using two widely adopted selective scanning detection methods (FST statistics and Piratio). Functional annotation and enrichment analysis of these genes identified 13 genes associated with the lambing rate, which were enriched in pathways such as the transforming growth factor-β signaling pathway (BMPR2, ID2, SMAD7, THBS1, and RBX1), renal cell carcinoma (PAK1, ELOC), inositol phosphate metabolism (PLCZ), non-homologous terminal junction (RAD50), ABC transporters (ABCC4), and the NET pathway (H2B, H4, and H2A). …”
Get full text

Postimplementation Evaluation in Assisted Living Facilities of an eHealth Medical Device Developed to Predict and Avoid Unplanned Hospitalizations: Pragmatic Trial by Jacques-Henri Veyron, François Deparis, Marie Noel Al Zayat, Joël Belmin, Charlotte Havreng-Théry

“…Nurse assistants (NAs) at the assisted living facilities used a smartphone app to complete a questionnaire on the functional status of the patients, comprising electronic patient-reported outcome measures (ePROMs); these were analyzed in real time by a previously designed machine learning algorithm. …”
Get full text

The Role of Scintigraphy and Hybrid Single-Photon Emission Tomography in Comparison with Laboratory Data in a Comprehensive Examination of Patients with Secondary Hyperparathyroidi... by V. Е. Prokina, А. А. Ansheles, A. V. Tarasov, A. S. Ametov, V. B. Sergienko

“…Objective: to estimate the possibilities and determine the diagnostic value of scintigraphy and single-photon emission computed tomography combined with computed tomography (SPECT/CT) in the assessment of the functional state of parathyroids in comparison with laboratory data in patients with secondary hyperparathyroidism (SHPT).   …”
Get full text

Assessment of some cytokines levels in a pauci-immune crescentic glomerulonephritis patients by Dina A. A. Al-Roubaey, Hawraa Ghaleb Idreess, Eman Hasani AL-Salami, Nadia Habeeb Sarhan, Ibtihal Riyadh Najeeb

“…These results indicate a functional role of IL-6, IL-17, IL-18, and INF-γ in ANCA-mediated neutrophil activation by the interdependence of IL-6, IL-17, IL-18, and INF-γ priming for ANCA responses. …”
Get full text

Proteomic and In Silico Analyses Highlight Complement System’s Role in Bladder Cancer Immune Regulation by Tuğcan Korak, İbrahim Halil Baloğlu, Murat Kasap, Elif Damla Arisan, Gurler Akpinar, Serdar Arisan

“…Protein network analysis and hub protein detection were performed using Cytoscape (v.3.10.3), while functional annotation was carried out using EnrichR. …”
Get full text

Describing Pulmonary Nodules Using 3D Clustering by Amera Al-Funjan, Farid Meziane, Rob Aspin

“…This paper combines algorithms to cluster and define nodule’s features in 3D visualization. Applying some 3D functions to the objects, clustered using the K-means technique of CT lung images, provides a 3D visual exploration of the nodule shape and location. …”
Get full text

Efficacy and neural mechanism of acupuncture treatment in older adults with subjective cognitive decline: study protocol for a randomised controlled clinical trial by Jun Wang, Ping Zhou, Xu Wang, Chao-Qun Yan, Jian Feng Tu, Shang-Qing Hu, Jian-Wei Huo, Zhong-Yan Wang, Guang-Xia Shi, Ya-Nan Zhang, Jun-Qiu Li, Cun-Zhi Liu

“…At this very early stage of decline, intervention could slow the rate of incipient decline to prolong and preserve cognitive and functional abilities. However, there is no effective treatment recommended for individuals with SCD. …”
Get full text

To study the prevalence of metabolic-associated fatty liver disease in a tertiary hospital in Bundelkhand region by Neha Rathore, Kuldeep Chandel, Ajeet Singh, Aniket Ashok Satale, Gaurav Singh

“…Its prevalence is increasing, particularly in developing regions, necessitating early detection and intervention. Aims and Objectives: This study aims to determine the prevalence of MAFLD in a tertiary care hospital and assess the demographic profile and associated risk factors in the Bundelkhand region. …”
Get full text

Primary vitrectomy in total and subtotal hemophthalmos of traumatic etiology by S. N. Subbotina, S. S. Shamkin, A. B. Stepanyants

“…An unfavorable outcome (lacking or incorrect light perception) was observed in 4 cases (9.75%), a relatively favorable functional outcome in the form of objective vision less than 0.1, in 17 cases (41.5%), a favorable outcome with visual acuity above 0.15 in 20 cases (49%). …”
Get full text

Therapeutic effect of cardiac rehabilitation on patients with long COVID combined with coronary heart disease: a retrospective study by Hui Du, Xia Du, Xinyu Lei, Gang Wang, Zhengtao Wang, Yiting Du, Fangfang Bai, Dajiang Yuan

“…ObjectivesTo investigate the efficacy of cardiac rehabilitation in patients with long COVID combined with coronary heart disease (CHD).MethodsThis retrospective study included 89 patients with long COVID, who were divided into CHD group and non-CHD group. …”
Get full text

Preventing respiratory illness in cerebral palsy: Results of a pilot randomized controlled trial. by Ryan J Coller, Kristina Singh-Verdeflor, Jens Eickhoff, Paul J Chung, Heidi M Kloster, Christopher C Cushing, Danielle M Gerber, Barbara J Katz, Siem Ia, Teresa Wagner, Roxana Delgado-Martinez, Gemma Warner, Lorena Porras-Javier, Thomas S Klitzner, Carlos F Lerner

“…This study's objective was to determine RE-PACT's feasibility, acceptability, fidelity, and estimated effect size.…”
Get full text

Serum miR-155–5p assists the diagnostic sensitivity and accuracy of low-dose spiral CT imaging in early lung cancer by Fei Li, Wenwen Han, Hailong Sun

“…MicroRNAs have been considered an approach for screening cancers, and the function of miR-155–5p in lung cancer has been previously revealed. …”
Get full text

Comprehensive analysis of SQOR involvement in ferroptosis resistance of pancreatic ductal adenocarcinoma in hypoxic environments by Quan Lin, Shiwei Guan, Minghui Peng, Kailun Zhang, Hewei Zhang, Taoming Mo, Haibo Yu

“…In vitro hypoxia cell models, SQOR knockdown experiments and nude mouse xenograft models were used to verify the regulatory function of SQOR on ferroptosis.ResultsPDAC exhibited significantly higher hypoxia levels than normal tissues, correlating with reduced overall survival in patients. …”
Get full text

Monitoring SARS-CoV-2 seroprevalence over time among pregnant women admitted to delivery units: Suitability for surveillance. by Mariana Yumi Miyadahira, Maria de Lourdes Brizot, Neal Alexander, Ester Cerdeira Sabino, Lea Campos de Oliveira da Silva, Mara Sandra Hoshida, Ana Maria da Silva Sousa Oliveira, Ana Claudia Silva Farche, Rossana Pulcineli Vieira Francisco, Philippe Mayaud

“…SARS-CoV-2 seroprevalence was computed as smooth spline function over time with 95% confidence intervals (CI). …”
Get full text

Vision-Related Quality of Life among Patients Attending the Diabetes and Eye Clinics in Kenyatta National Hospital, Kenya by Nerice Emade, Joseph Nyamori, Margaret Njuguna, Lucy Njambi, Stephen Gichuhi

“…Visual impairment, patients’ worries, and restrictions due to diabetes mellitus and diabetic retinopathy may affect patients’ quality of life. Objective. Our main objective was to determine the overall vision-related quality of life (VRQoL) among patients with diabetes mellitus attending the diabetes and eye clinics in Kenyatta National Hospital, Kenya. …”
Get full text

The range of clinical manifestations of congenital glaucoma found in people seeking consultation at the Helmholtz National Medical Research Center of Eye Diseases by L. A. Katargina, A. A. Sorokin, N. N. Arestova, A. Yu. Panova, T. B. Kruglova, L. V. Kogoleva, T. V. Sudovskaya

“…The timing of CG manifestation is determined by the degree of congenital abnormalities in the eye drainage system that, together with secondary structural changes of eyes (cornea, axial length, retina and ONH) entail a more severe prognosis of PCG in case of an early disease onset. New objective criteria are needed to assess the severity and prognosis of PCG, which is important for the preservation of visual functions, prevention of low vision and blindness.…”
Get full text