As a phenomenon: Ramadan fasting improves olfactory performance by Doğan Çakan, Hüseyin Baki Yılmaz, Harun Cansız, Haluk Çevik, Michael C. F. Tong, Begüm Bahar Yılmaz, Zeliha Kübra Çakan

“…Abstract Objective The present study objectived to investigate the influence of Ramadan fasting (RF) on olfactory function. …”
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Circ-PDE1C/miR-766-3p/SGTB axis regulates the IL-1β-induced apoptosis, inflammation and oxidative stress in human chondrocytes by Lixia Gao, Tao He, Qingkui Hu, Yan Ma

“…Circ-PDE1C could interact with miR-766-3p to serve as miRNA sponge. The function of si-circ-PDE1C was attributed to the inhibition of miR-766-3p. …”
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Non-invasive visualisation of long-lasting brain metabolic alterations in murine pseudo-infection model using parahydrogen-polarised [1-13C] pyruvate MRI by Hayate Tomiyama, Masaki Yamasaki, Takayuki Isagawa, Norihiko Takeda, Takuya Hashimoto, Hiroshi Hirata, Shingo Matsumoto

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The Association of Reactive Oxygen Species with High-Risk Human Papilloma Virus Infection and Some Sperm Parameters in a Samples of Iraqi Idiopathic Infertile Males by Mustafa Dawood, Arwa Al-Shuwaikh, Ula Al-Kawaz

“…This OS may impact sperm function and fertility in men. Objective: To find out the association of ROS with HR-HPV infection and sperm parameters with group of infertile Iraqi patients with unknown causes. …”
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Hepatic enzyme alterations as prognostic markers in neonates with hypoxic-ischemic encephalopathy: A hospital-based prospective cohort study. by Dr . Eaka Mahesh, Dr. Ragini Mutukulla, Dr . Durgesh Velupula, Dr. Bindhu Vechangi

“…HIE staging was performed using the modified Sarnat and Sarnat criteria. Liver function tests, including serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), and alkaline phosphatase (ALP), were measured on Days 1 and 3. …”
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Immunohistochemical features of cyclooxygenase-2 expression in endometrial hyperplasia without atypia by N. Ye. Horban, T. D. Zadorozhna, I. B. Vovk, V. K. Kondratiuk, S. M. Kilichevych

“…Hyperplastic processes of the endometrium without atypia have been an urgent problem for researchers around the world for a long time, given the current position of cancer alertness and violations of reproductive function. Objective. To study immunohistochemically the expression level of the new biomarker - cyclooxygenase-2 (COX-2) in various types of endometrial hyperplasia without atypia in samples of altered endometrial tissue from 30 patients of reproductive age (39.47 ± 1.1 years). …”
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RNA-seq analysis reveals key genes associated with downregulation of APE1 in esophageal squamous cell carcinoma by Alan Chu, Xiao Liu, Shijia Liu, Mengxi Li, Rui Song, Lanlan Gan, Yongtai Wang, Zongwen Liu, Chen Sun

“…The three core genes of FN1, TNF, and IL-6 were confirmed using qRT-PCR and Western blotting, and the results were consistent with the transcriptome sequencing results.ConclusionKnocking out APE1 can affect the function, related pathways, and downstream target gene expression of ESCC cells. …”
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SHOULD DISEASE-MODIFYING THERAPY BE STOPPED IN PATIENTS WITH RHEUMATOID ARTHRITIS BEFORE ENDOPROSTHETIC JOINT REPLACEMENT? by N. A. Savenkova, V. N. Amirdzhanova, S. A. Makarov, A. L. Logunov, M. A. Makarov, V. V. Kolomatsky, D. V. Goryachev

“…Objective: to analyze disease activity, functional state, quality of life (QL), and the frequency of infectious complications in methotrexate (MT) – or leflunomide (LF)-treated patients with rheumatoid arthritis (RA) who had undergone endoprosthetic replacement of the large joints of the lower limbs. …”
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OGT-induced O-GlcNAcylation of NEK7 protein aggravates osteoarthritis progression by enhancing NEK7/NLRP3 axis by Chunlei He, Qiang Wu, Zhaogan Zeng, Yadong Yang, Huabin He, Meiyu Hu, Sheng Liu

“…However, its specific functions in osteoarthritis (OA) progression remain undetermined.Objective This study focused on the target proteins of OGT-induced O-GlcNAcylation in OA and the specific functional mechanism.Methods The levels of total O-GlcNAc and OGT were measured in both in vitro and in vivo OA models using western blot. …”
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Effect of simvastatin on microinflammation in patients with uremia by SU Bo, LI Yi

“…Objective To analyze the effect of simvastatin on microinflammation in patients with uremia.Methods Randomly The selected 76 patients with chronic renal failure in our hospital from January 2015 to January 2017 were divided into the control group and the observation group.The control group was treated with basic treatment and dialysis.The observation group was treated with simvastatin on the basis of the basic treatment program.The serum levels of inflammatory factors,nutritional indexes,blood lipid,renal function and cardiac function indexes were detected.Results Before the treatment,there was no significant difference between the two groups in IL-6,TNF-α,hs-CRP and Alb contents.After treatment,IL-6,TNF-α,hs-CRP and Alb contents were significantly increased in both two groups as compared with those before treatment,but IL-6,hs-CRP and TNF-αlevels were significantly lower,and Alb was significantly higher in the observation group than those in the control group(P<0.05).Before treatment,there was no significant difference in the renal function and blood lipid indexes between two groups.After treatment,the renal function indexes and blood lipid indicators were improved significantly in the two groups as compared with those before treatment.SCr,HDL-C,TG,LDL-C and TC were significantly better in the observation group than those in the control group(P<0.05).Before treatment,there was no significant difference in IVST,LVM and LVMI between two groups(P>0.05).After treatment,IVST,LVM and LVMI indexes in the two groups were decreased,but the decrease was not obvious with the difference being not statistically significant(P >0.05).Conclusions Simvastatin exerts good anti-inflammatory effects,and its combination with basic dialysis for uremia patients could effectively improve the microinflammatory state of patients,improve renal function and blood lipid indexes,and reduce the incidence of adverse reactions.…”
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Traditional Chinese exercises for the treatment of neuropsychiatric symptoms in Parkinson’s disease: A systematic review and meta-analysis by Weiqiang Tan, Zhaoquan Pan, Jiawei He, Tiexiong Wu, Feng Wu, Yachen Xu, Lisha Liu, Ziyu Yang, Chunrui Li, Yuechen Hu, Muxi Liao

“…Objective: To systematically evaluate the efficacy of traditional Chinese exercises (TCEs) for neuropsychiatric symptoms (NPSs) in patients with Parkinson’s disease. …”
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Correlation of the FIB-4 Liver Biomarker Score with the Severity of Heart Failure by Roxana Buzas, Paul Ciubotaru, Alexandra Corina Faur, Marius Preda, Melania Ardelean, Doina Georgescu, Patrick Dumitrescu, Daniel Florin Lighezan, Mihaela-Diana Popa

“…<i>Background and Objectives</i>: Heart failure is associated with high morbidity and mortality and linked with several pre-existing health conditions and risk factors. …”
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ACTIVE, ACTUATED, AND ASSISTIVE: A SCOPING REVIEW OF EXOSKELETONS FOR THE HANDS AND WRISTS by Angel Galbert, Arjan Buis

“…The design and method of device function of 121 devices were analysed. Muscle and joint movement detection were highly used to control device movement. …”
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Transponder: Support for Localizing Distressed People through a Flying Drone Network by Antonello Calabrò, Eda Marchetti

“…<i>Results:</i> The Transponder functionalities have been proven to enhance and expedite the detection of missing persons. …”
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Methylglyoxal-induced RNA modifications decrease RNA stability and translation and are associated with type 2 diabetes by Edwin De Jesus Lopez Gonzalez, SWT Lai, Kelani Sun, Caree R. Carson, Carlos Hernandez-Castillo, Tala Zoukari, Kassandra Lopez, Jianying Zhang, Thomas Blevins, John Termini, Sarah C. Shuck

“…Objectives: Methylglyoxal (MG), a reactive aldehyde generated as a byproduct of glucose and lipid metabolism, is known to modify nucleic acids and proteins, altering their structure and function. …”
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Human umbilical cord mesenchymal stem cells improve disease characterization of Sjogren's syndrome in NOD mice through regulation of gut microbiota and Treg/Th17 cellular immunity by Yao Zou, Wei Xiao, Dongzhou Liu, Xianyao Li, Lihua Li, Lijuan Peng, Ying Xiong, Haina Gan, Xiang Ren

“…Mesenchymal stem cells (MSCs) and derived exosomes (MSCs‐exo) have exhibited promising results in treating SS. Object This study aimed to investigate the effect and mechanism of human umbilical cord MSCs (UC‐MSCs) on SS. …”
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Research on small target ship recognition based on feature fusion method and hybrid attention model by Ronghui YAN, Qian GUO, Ming LEI, Yanxiang CAI, Jianfeng YANG

“…ObjectiveThis paper addresses a problem affecting small target ship detection in which network models have a low recognition rate caused by the insignificance of features in small target ships. …”
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Epigenetic-modification associated hnRNPA3 acts as a prognostic biomarker and promotes malignant progression of HCC by Xufan Cai, Weihui Guo, Fang Wu, Weilang Xu, Tao Ding, Yizhe Diao, Lei Wang, Zhenyuan Qian, Guangyuan Song

“…Abstract Objective hnRNPA3 is highly expressed in numerous malignancies, including hepatocellular carcinoma (HCC), but its function and mechanism has not been elucidated. …”
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Features of ankylosing spondylitis at different stages in men and women by I. A. Cherentsova, E. N. Otteva

“…The incidence of ankylosing spondylitis (AS) has recently increased with a substantial rise in the proportion of female patients, making this investigation relevant.Objective: to investigate the clinical and laboratory parameters of inflammatory activity and functional status in male and female patients with AS at different stages of the disease.Patients and methods. …”
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Effect of Jiawei Fuzi Lizhong decoction on Cys C,T lymphocyte subsets and vWF of patients with acute drug-induced renal damage by LAN Fang, XIE Li-ping, XIE Yong-xiang, TAO Zhi-hu, SHI Wei

“…Blood samples were taken to detect T lymphocyte subsets and v WF. Results After treatment,the renal function of treatment group and control group were improved,and the levels of BUN,SCr and Cys C decreased as compared with those before treatment,with the difference being statistically significant. …”
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