Damage Diagnosis in 3D Structures Using a Novel Hybrid Multiobjective Optimization and FE Model Updating Framework by Nizar Faisal Alkayem, Maosen Cao, Minvydas Ragulskis

“…Modal characteristics are employed to develop the objective function by considering two subobjectives, namely, modal strain energy (MSTE) and mode shape (MS) subobjectives. …”
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Bearing Fault Diagnosis Method based on Self-adaptive Stochastic Resonance of Genetic Algorithm and VMD by Zhang Chao, He Yuanyuan

“…And then,the signal-to-noise ratio of output signal is defined as the objective function. By using the genetic algorithm,the a and b that are structure parameter of re-scaling stochastic resonance are optimized,and the optimal value is selected to drag-in the re-scaling stochastic resonance,the de-noising of measured signal is carried out,Finally,the de-noising signal is decomposed by VMD,from the component spectrum diagram of each IMF,the bearing fault characteristic frequency can be found. …”
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A case of severe Epstein-Barr viral hepatitis with the development of hepatic cell failure and encephalopathy in a 1-year old child by L. V. Kramar

“…Objective: The article describes a clinical case of severe Epstein-Barr viral hepatitis in a child aged 1.Materials and methods. …”
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Diagnostic model for COPD patients with nocardia infection: a study based on clinical features and risk factors by Kai Zhang, Kangli Yang, Hongmin Wang

“…Demographic, laboratory, pulmonary function, and imaging data were collected. Multivariate logistic regression identified independent predictors, which informed a nomogram model. …”
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Clinical features and prognostic analysis of AKI in the internal medicine departments by XUE Xian, TANG Xiao-jing, ZHANG Di, SHEN Ai-wen, MEI Chang-lin

“…Objective To explore the clinical features of patients with acute kidney injury(AKI)in the internal medicine departments.Methods The kidney function indexes of the internal medicine patients were collected in Shanghai Changzheng Hospital from 2011 to 2012.According to the AKI diagnostic criteria of KDIGO in 2012,we screened out the AKI patients who met the criteria.By retrospectively studying their clinical data,we analyzed and summarized their clinical characteristics and the factors affecting the prognosis.Results From January 2011 to December 2012,there were a total of 33 332 cases of internal medicine patients in our hospital and 245 of them met the criteria of AKI.The incidence of AKI was 0.74%in internal medicine departments while the detection rate of AKI was 35.92%.The proportions of patients with AKI stage 1 to 3 were 42.45%,20.41% and 37.14%,respectively.Among all the internal medicine departments,patients in the department of nephrology accounted for 33.47%,followed by the department of cardiology(20.00%),gastroenterology(11.84%)and infectious disease(10.61%).The incidence of AKI from high to low was infection disease department(1.70%),nephrology department(1.37%),and cardiology department(1.11%).Of all the hospitalized patients with AKI,71.84% discharged with a better health condition and the kidney function discovered in only 34.69% of the discharged patients;28.16% died or gave up treatment.The most common departments with high fatality rate were the department of infectious disease(21.74%),gastroenterology and cardiology.Infection was the main cause of the AKI in internal medicine departments.Logistic regression analysis showed that higher AKI stage,more AKI risk factors,combination with liver disease or tumor were risk factors for death and giving up treatment,while chronic kidney disease was the protective factor.ConclusionsAKI is common in internal medicine system,with a high mortality rate and a higher recognition rate than perioperative AKI.Except for the department of nephrology,cardiology,departments of infectious disease and gastroenterology have heavy burden of AKI.The advanced stage of AKI,more risk factors,and comorbidities such as liver disease or tumor were associated with poor prognosis.…”
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Sensitivity and Specificity of Three Measures of Intrinsic Capacity in Older People Aged 80 and Over in Nursing Homes by Ma L, Zheng E, Fang Y, Chen H, Zhou C, Cai S, Luo F, Jiang W, Wang J, Ning X, Tu H, Yin Z

“…IC spans five function domains: Locomotor, psychological, cognitive, vitality, and sensory (including vision and hearing). …”
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Exploring Factors Related to Social Isolation Among Older Adults in the Predementia Stage Using Ecological Momentary Assessments and Actigraphy: Machine Learning Approach by Bada Kang, Min Kyung Park, Jennifer Ivy Kim, Seolah Yoon, Seok-Jae Heo, Chaeeun Kang, SungHee Lee, Yeonkyu Choi, Dahye Hong

“…Individuals with subjective cognitive decline and mild cognitive impairment represent predementia stages in which functional decline may still be reversible. Therefore, identifying factors related to social isolation in these at-risk groups is crucial, as early detection and intervention can help mitigate the risk of further cognitive decline. …”
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Multimodal Imaging of Brain Metastasis-Derived Extracellular Vesicles Using Superparamagnetic Iron Oxide Nanoparticle Labeling by Feginn Berle B, Juliussen S, Castilho Á, Solel E, Sdik Saed H, Vanderpoorten O, Lunavat TR, Thorsen F, Rigg E

“…The labeled EVs were characterized using transmission electron microscopy (TEM), colorimetric iron assays, dynamic light scattering and nanoparticle tracking analysis (NTA) in Nanospacer devices. The functionality and visualization of SPION-labeled EVs were assessed in fetal rat brain organoids (FRBOs) using Prussian blue staining, TEM, and MRI. …”
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Investigating the Role of the Zinc Finger Protein ZC2HC1C on Autism Spectrum Disorder Susceptibility by Simone Treccarichi, Mirella Vinci, Antonino Musumeci, Rosanna Galati Rando, Carla Papa, Salvatore Saccone, Concetta Federico, Pinella Failla, Martino Ruggieri, Francesco Calì, Agata Polizzi, Andrea Praticò

“…<i>Conclusions</i>: Further analyses are needed via in vitro functional assays or by <i>ZC2HC1C</i> gene knockout to validate its functional role.…”
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Assessment of molecular and morphological dynamics during long-time in vitro cultivation of cryopreserved human ovarian tissue: risk of genetic alterations by Wanxue Wang, Wanxue Wang, Plamen Todorov, Evgenia Isachenko, Gohar Rahimi, Gohar Rahimi, Markus Merzenich, Nina Mallmann-Gottschalk, Yang Zhou, Yang Zhou, Jilong Yao, Xuemei Li, Volodimir Isachenko

“…This technology includes the following stages: saturation by permeable cryoprotectants, freezing, thawing, removal of cryoprotectants, as well as tissues in vitro or in situ culture.ObjectiveEvaluation of quality of tissue after cryopreservation and in vitro culture with the aim of detection of genetic and molecular changes in cells.MethodsOvarian tissue was frozen in 6% ethylene glycol and 6% dimethyl sulfoxide with speed of cooling 0.3°C/min and thawed at 100°C. …”
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Contrast-Enhanced Mammography Accuracy in Assessing Preoperative Breast Tumor Size by M. Balbino, A. Ancona, F. Masino, S. Suriano, S. Cantore, M. Montatore, G. Guglielmi

“…Imaging techniques (ultrasound, mammography, and magnetic resonance imaging (MRI)) play a crucial role in tumor detection and evaluation. The last emerging technique is contrast-enhanced mammography (CEM) which provides both morphological and functional information.Objective: to evaluate CEM accuracy in measuring breast tumor lesions. …”
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Comprehensive bioinformatics analysis identified HMGB3 as a promising immunotherapy target for glioblastoma multiforme by Libin Wang, Peizhi Xu, Xinglong Li, Qinghua Zhang

“…Abstract Objective Glioblastoma multiforme (GBM) presents significant therapeutic challenges due to its heterogeneous tumorigenicity, drug resistance, and immunosuppression. …”
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Elite Tennis Players with a Weak Rotator Cuff: The Paradox of Infraspinatus Atrophy - A Clinical Commentary and Practical Approach by Yannick Lambrecht, Leon Philipp Knoche, Lukas Höller

“…Diagnosis involves visual inspection, palpation, and functional tests, though ultrasound imaging offers a more objective assessment of infraspinatus muscle thickness. …”
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Prevalence and Symmetry of Positional Anomalies in Second Permanent Molars: Study of Romanian Patients by Rahela Tabita Moca, Abel Emanuel Moca, Mihai Juncar

“…Background/Objectives: This study aimed to investigate the prevalence and characteristics of positional anomalies in second permanent molars among Romanian patients. …”
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Intranasal administration of stem cell derivatives for the treatment of AD animal models: a systematic review and meta-analysis by Zilin Hua, Nan Zhou, Zijing Zhou, Zewei Fu, Ruiyun Guo, Herman Yao Akogo, Jiayin Yang, Meixuan Yu, Yujie Jiang, Siyi Lan, Haixia Chang, Jun Ma, Huixian Cui

“…Auxiliary outcomes CD68 and GFAP also exhibited decreased expression levels. Improved cognitive function was evident, as measured by increased target quadrant dwell time (MD = 10.17, p < 0.00001) and decreased escape latency (MD = -15.74, p = 0.003) in behavioral experiments, and enhanced recognition in the Novel Object Recognition Test (NORT) (SMD = 1.10, p = 0.006). …”
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Correlação entre os achados clínicos da deglutição e os achados da tomografia computadorizada de crânio em pacientes com acidente vascular cerebral isquêmico na fase aguda da doenç... by Anna Flávia Ferraz Barros, Soraia Ramos Cabette Fábio, Ana Maria Furkim

“…In 50% of the patients with functional deglutition and in 46% of the dysphagics the lesion was in the left hemisphere. …”
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LINC00313 promotes the aggressiveness and tumorigenesis of cholangiocarcinoma through targeting miR-320b and MITF by Ziyu Wang, Jiao Li, Jing Xu, Tingqiu Wan, Yunjin Ya, Xi Li, Xi Wang, Yan Jin

“…Methods Clinical samples were collected to examine the expression pattern of LINC00313, miR-320b, and MITF using RT-qPCR and western blot analysis. Functional experiments, including cell proliferation, migration, and invasion assays, as well as apoptosis detection, were performed to assess the malignant properties of cholangiocarcinoma cells. …”
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Ulinastatin modulates TRPM4 expression and apoptosis to mitigate cognitive dysfunction in aged perioperative neurocognitive disorder rats by Xiaohui Xia, Jiayi Li, Mengmeng Zhang, Chunyan Zhang, Keliang Lu, Huirong han

“…Forty eighteen-month-old male Sprague‒Dawley rats were randomly divided into four groups: the sham group, surgery group (internal fixation of tibial fracture), ulinastatin group (ulinastatin + surgery), and 9-phenanthrol group (TRPM4 channel inhibitor 9-phenanthrol + surgery). The neurocognitive function of the rats was detected using the Y-maze and new object recognition (NOR) tests. …”
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Pattern-Reversal Visual Evoked Potentials Tests in Persons with Type 2 Diabetes Mellitus with and without Diabetic Retinopathy by Raghda S. Al-Najjar, Nehaya M. Al-Aubody, Salah Z. Al-Asadi, Majid Alabbood

“…Currently, diabetic retinopathy (DR) has a wide recognition as a neurovascular rather than a microvascular diabetic complication with an increasing need for enhanced detection approaches. Pattern-reversal visual evoked potentials (PRVEPs) test, as an objective electrophysiological measure of the optic nerve and retinal function, can be of great value in the detection of diabetic retinal changes. …”
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Contribution of contrast-enhanced ultrasound in the diagnosis of adnexal torsion (AGATA): protocol for a prospective comparative study by Marine Beaumont, Olivier Morel, Charline Bertholdt, Gabriela Hossu, Aboubaker Cherifi, Rémi Pillot, Kévin Guillez, Anne-Laure Fijean

“…The secondary objectives are: (1) to describe the perfusion parameters of the ovaries by contrast-enhanced ultrasound, (2) to compare diagnostic performance of contrast ultrasound with bidimensional (2D) Doppler for the detection of adnexal torsion, (3) to describe the perfusion parameters of the ovarian as a function of the degree of adnexal torsion, (4) to compare perfusion parameters before and after ovarian detorsion and (5) to describe perfusion parameters of the ovarian by using MicroVascular Flow technique.Methods and analysis This is a monocentric, prospective comparative, non-randomised, open and interventional study. …”
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