Deep Learning Algorithm for Optimized Sensor Data Fusion in Fault Diagnosis and Tolerance by M. Elhoseny, Deepak Dasaratha Rao, Bala Dhandayuthapani Veerasamy, Noha Alduaiji, J. Shreyas, Piyush Kumar Shukla

“…The enhanced RPN also has a loss function (object detection loss, bounding box loss and target classification loss), an estimate of ROI and feature extraction network (FEN). …”
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Object fine-grained discrimination as a sensitive cognitive marker of transentorhinal integrity by Emma Delhaye, Gabriel Besson, Mohamed Ali Bahri, Christine Bastin

“…Understanding its role in cognition is key to detecting early cognitive impairments in AD. This study tested the hypothesis that the tErC supports fine-grained representations of unique individual objects, sensitively to the granularity of the demanded discrimination, influencing both perceptual and mnemonic functions. …”
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Optimizing staging of Meniere’s disease: integrating electrocochleography with vestibular tests by Muchen Huang, Muchen Huang, Xianren Wang, Xianren Wang, Minqi Chen

“…ObjectivesThis study aimed to evaluate the diagnostic and staging efficacy of integrating electrocochleography (ECochG) with vestibular function tests—specifically cervical and ocular vestibular evoked myogenic potentials (cVEMP and oVEMP), caloric test (CT), and video head impulse test (vHIT)—for Ménière’s disease (MD).DesignData were collected from 54 MD patients (66 affected ears) admitted to a hospital between January 2023 and January 2024. …”
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Empirical Evaluation and Analysis of YOLO Models in Smart Transportation by Lan Anh Nguyen, Manh Dat Tran, Yongseok Son

“…You Only Look Once (YOLO) and its variants have emerged as the most popular real-time object detection algorithms. They have been widely used in real-time smart transportation applications due to their low-latency detection and high accuracy. …”
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Assessment of functional disability and associated factors among people with severe mental illness attending care at public hospitals in Harar town, Eastern Ethiopia: a cross-secti... by Betelhem Mulugeta Worku, Niguse Yigzaw, Getachew Tesfaw, Seblewongel Tinsae, Abiy Mulugeta

“…Objective This study aimed to assess functional disability and associated factors among people with severe mental illness attending public hospitals in Harar town, Eastern Ethiopia.Setting An institution-based cross-sectional study was conducted in public hospitals found in Harar town, Eastern Ethiopia, from 1 April to 10 May 2023.Participants A total of 342 patients with severe mental illness attending public hospitals in Harar town, Eastern Ethiopia, were included.Outcome measure The main outcome of this study was functional disability, which was measured using a 12-item version of the WHO Disability Assessment Schedule.Results In this study, the mean (±) score of functional disability among patients with severe mental illness was 31.8 (±9.6) (95% CI: 30.7 to 32.8). …”
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Cognitive costs in motor-cognitive performance assessments depend on movement complexity and cognitive task design by Gülsa Erdogan, Lutz Vogt, Florian Giesche, David Friebe, Winfried Banzer, Winfried Banzer, Andreas Mierau, Andreas Mierau, Thorben Hülsdünker, Thorben Hülsdünker

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Functional role of pyruvate kinase M2 in cell cycle arrest and extracellular matrix secretion of renal tubular epithelial cell induced by transforming growth factor-β1 by Wu Hong-luan, An Ning, Chen Xiao-cui, Pang Hao-wen, Yang Chen, Liu Hua-feng

“…Objective To explore the functional role of pyruvate kinase M2（PKM 2） in cell cycle arrest and extracellular matrix secretion of renal tubular epithelial cell induced by transforming growth factor-β1（TGF-β1）.Methods HK-2 cells were stimulated by TGF-β1 for establishing an in vitro model of renal tubulointerstitial fibrosis.The function of dimeric PKM2 was suppressed by a PKM2 allosteric agent TEPP-46 or its antagonist shikonin.The expressions of fibronectin, collagen I and connective tissue growth factor（CTGF） were detected by Western blot.The ratio of HK-2 cells in cycle phase was performed by propidium iodide staining and analyzed by flow cytometry.Also the expression of cell cycle inhibitor p21 was detected by Western blot.Results As compared with control-treated cells, a treatment of TGF-β1 significantly boosted the levels of extracellular matrix fibronectin, collagen I,pro-fibrotic CTGF and dimeric PKM2.By contrast, TEPP-46 or shikonin markedly suppressed the elevations of fibronectin, collagen I and CTGF.Moreover, an inhibition of dimeric PKM2 by TEPP-46 or shikonin remarkably suppressed the proportion of TGF-β1-treated HK-2 cells in G1 phase through a down-regulation of p21.Conclusion Dimeric PKM2 promotes cell cycle arrest and extracellular matrix secretion of renal tubular epithelial cell induced by TGF-β1.And targeting dimeric PKM2 may represent a novel therapeutic strategy for delaying the progression of renal tubulointerstitial fibrosis.…”
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Therapeutic efficacy and mechanism of artesunate for mouse model of polycystic ovary syndrome by WANG Xueling, WANG Xueling, ZHONG Peiling, ZHONG Peiling, ZHAO Zhipeng

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Prognostic value of matrix metalloproteinases and transforming growth factor – β in kidney cancer by A. I. Tarasenko, A. N. Rossolovskiy, O. L. Berezinets, A. B. Bucharskaya, S. S. Pakhomiy, A. O. Efimova, G. N. Maslyakova

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Gender-specific and age-specific associations of the homoeostasis model assessment for IR (HOMA-IR) with albuminuria and renal function impairment: a retrospective cross-sectional... by Wen-Cheng Li, Jau-Yuan Chen, Wei Yu, Yu-Ping Liu, Yi-Chuan Chen, Hsiung-Ying Huang, Chieh-An Lin, Xue-Jie Xiong

“…Objectives The study aimed to investigate the association of insulin resistance (IR), which was estimated by the homoeostasis model assessment for IR (HOMA-IR), with albuminuria and renal function impairment in a general Chinese population.Design A retrospective cross-sectional study.Setting and participants A total of 13 742 adults (age: ≥18 years) who underwent a health check-up at a hospital in Southeast China during 2013–2014 were enrolled. 216 subjects were excluded due to lack of enough fasting time, be pregnant, have chronic diseases influencing metabolic functions or have glomerulonephritis, renal cancer, kidney transplant. …”
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Evaluation of the Vestibulocochlear System in Patients with Pseudoexfoliation Syndrome by Mustafa Değer Bilgeç, Nagehan Erdoğmuş Küçükcan, Leman Birdane, Armağan İncesulu, Nilgün Yıldırım

“…Objectives:Patients with pseudoexfoliation syndrome (PES) can also have sensorineural hearing loss as well as balance problems. …”
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Cognitive Decline in Patients With Trigeminal Neuralgia: A Resting‐State fMRI Study by Xueyun Deng, Lihua Liu, Jiafei Chen, Zhi Liu, Hua Feng

“…ABSTRACT Objective This study utilized functional magnetic resonance imaging (fMRI) data to investigate cognitive function changes in trigeminal neuralgia (TN) patients and healthy controls (HCs), and to elucidate the potential mechanism. …”
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Quantifying task-locked information transmission between cortical areas with TMS-EEG by Zhaohuan Ding, Wenbo Ma, Leixiao Feng, Mingsha Zhang, Xiaoli Li

“…Objective: This study aims to develop TMS-EEG (Transcranial magnetic stimulation combined with EEG) technology to detect task-locked neural network activation and dynamically quantify information transmission. …”
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Disrupted synaptic gene expression in Fabry disease: Findings from RNA sequencing by Laura López-Valverde, María E. Vázquez-Mosquera, Cristóbal Colón-Mejeras, J. Víctor Álvarez, Beatriz Martín López-Pardo, Lluis Lis López, Rosario Sánchez-Martínez, Manuel López-Mendoza, Mónica López-Rodríguez, Eduardo Villacorta-Argüelles, María A. Goicoechea-Diezhandino, Francisco J. Guerrero-Márquez, Saida Ortolano, Elisa Leao-Teles, Álvaro Hermida-Ameijeiras, María L. Couce

“…Functional enrichment analysis highlighted processes related to synaptic function, specifically concerning chemical synaptic transmission and membrane potential regulation. …”
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Utilizing multiple diffusion metrics in evaluation of corticospinal tract injury in patients with glioblastoma by Ting Chen, Peipei Wang, Eryuan Gao, Jie Bai, Guohua Zhao, Kai Zhao, Gaoyang Zhao, Yu Zhang, Yong Zhang, Mengzhu Wang, Guang Yang, Boyan Xu, Xiaoyue Ma, Jingliang Cheng, Jingliang Cheng

“…ObjectivesThis study aimed to evaluate the efficacy of diffusion tensor imaging (DTI), diffusion kurtosis imaging (DKI), neurite orientation dispersion and density imaging (NODDI), and mean apparent propagator-magnetic resonance imaging (MAP-MRI) in detecting CST injury caused by GBM and to compare their performances.Materials and methodsWe enrolled 76 patients diagnosed with GBM with motor weakness (MW, n = 22) or normal motor (NM, n = 54). …”
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Effect of a compound nutrition preparation on wound healing after acute trauma in rats by XIN Wenbin, BAI Qian, NI Xiangmin

“…Objective‍　‍To explore the efficacy of a compound nutrition preparation on wound healing after acute trauma and investigate the underlying mechanism primarily. …”
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The Effect of Cerebellar Vermal rTMS with TBS Paradigm on Negative Symptoms, Cognitive Function and Serum Inflammatory Factors in Elderly Patients with Chronic Schizophrenia: a Ran... by DONG Xiaomei, ZHAO Hongyan, GENG Zhongli, XU Tianchao, WANG Qi

“…Objective Observing the effects of cerebellar vermis rTMS with theta burst stimulation (TBS) paradigm on negative symptoms, cognitive function, and serum inflammatory cytokine levels in elderly CSZ patients. …”
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Distortion-Tolerant 3-Dimensional Object Recognition Using Hybrid Joint Transform Correlator by Jyoti Bikash Mohapatra, Ram Kumar, Naveen K. Nishchal

“…The synthetic discriminant function is seamlessly integrated with the FJTC to ensure distortion-invariant 3-dimensional object recognition. …”
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基于IMU信号的人工智能上肢多关节运动状态识别系统构建——卒中后人工智能运动功能评估与检测系统建设前导研究 Construction of an Artificial Intelligence Upper Limb Multi-Joint Motion State Recognition System Based on IMU Signals—A Pre... by 程相鑫1，张烁1，杜松骏1，刘子阳1，周宏宇2，3，贾伟丽2，3，李子孝2，3，刘涛1 (CHENG Xiangxin1, ZHANG Shuo1, DU Songjun1, LIU Ziyang1, ZHOU Hongyu2,3, JIA Weili2,3, LI Zixiao2,3, LIU Tao1 )

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Development of a General Composite Scale (GENCOMS) for Progressive Neurodegenerative Diseases and Implications for the Assessment of Disease-Modifying Therapies by Samuel P. Dickson, Craig H. Mallinckrodt, Basia Rogula, Lauren C. Powell, Michele H. Potashman, Vladimir Coric, Gilbert J. L’Italien, Suzanne B. Hendrix

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