TWO CASES OF PRIMARY AMYLOIDOSIS PRESENTING WITH VERTEBRAL AMYLOIDOMA by Ebru Kavak Yavuz, Vehbi Demircan, Abdullah Karakus, Orhan Ayyildiz

“…Objective: Amyloidosis is a rare disease in which symptoms occur due to protein misfolding and the accumulation of amyloid fibrils in organs and tissues. 20 types of amyloid proteins have been identified. …”
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Effect and mechanism of HER2 antibody-drug conjugate combined with anti-PD-1 antibody in mouse bladder cancer models by HE Shuo, TAO Lu, WU Yue

“…At day 28, blood and tumor samples (n=5) were collected to detect myeloid-derived suppressor cells (MDSCs; CD11b⁺Gr1⁺) and regulatory T cells (Tregs; CD4⁺CD25⁺FOXP3⁺) with flow cytometry, tumor-infiltrating CD3⁺T, CD8⁺T, and FOXP3⁺T cells with immunohistochemical assasy, and liver/kidney functions [alanine aminotransferase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN), creatinine (CRE)] and tissue damage indicators [lactate dehydrogenase isoenzyme (LDH-L)]. …”
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Identification and Expression Analysis of the Phospholipase D Gene Family in Rice by Huasheng CAO, Tang LI, Liang XIONG, Fujun WANG, Shuguang LI, Haiyong GU, Gao HE, Shihu LIANG, Wenyong LUO

“…【Objective】Phospholipase D (PLD) plays a crucial role in plant growth, development, and stress response. …”
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Exploring the mechanism of triptolide inhibiting the motility of fibroblast-like synoviocytes in rheumatoid arthritis via RhoA/Rho-associated kinase axis, based on network pharmaco... by Jiacheng Shen, Jiacheng Shen, Jiacheng Shen, Yuxuan Fang, Yuxuan Fang, Nan Xu, Nan Xu, Hongyi Chen, Hongyi Chen, Miao Zhu, Miao Zhu, Dan Li, Dan Li, Zewen Chu, Masataka Sunagawa, Yanqing Liu, Yanqing Liu, Haibo Wang, Haibo Wang, Guoqing Li, Guoqing Li

“…Background and objectiveRheumatoid arthritis (RA) is a chronic autoimmune disease characterized by the hyperproliferation and invasive behavior of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS), which contributes to the degradation of articular cartilage and bone. …”
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Analysis of differences in physicochemical properties and bacterial community characteristics of rhizosphere soil in apple orchards under different cover treatments by HU Zhifang, CHENG Lijun, LI Yunguo, HUANG Guoyan, CAI Rongjing, MA Miandi, MA Jing, CHEN Chen, YANG Yanqun, LU Xingkai, QUAN Yong

“…[Objective] Cover cropping is a widely adopted soil management technique used in fruit tree cultivation. …”
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Reproducibility and validity of adapted clinical tests for the assessment of muscle strength in community-dwelling older adults living with Alzheimer’s disease by Marcos Paulo Braz de Oliveira, Letícia Bojikian Calixtre, Natália Oiring de Castro Cezar, Carla Lima-Truax, Brendon David Truax, Anielle Cristhine de Medeiros Takahashi, Tatiana de Oliveira Sato, Paulo Henrique Silva Pelicioni, Paula Regina Mendes da Silva Serrão, Larissa Pires de Andrade

“…Abstract Background Older adults living with Alzheimer’s disease (AD) have impaired executive functions and can therefore have greater difficulty following the instructions of assessment tests. …”
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RhIL-11 reverses liver damage in septic mice by STAT3-mediated M-MDSCs induction modulated by a parallel mTORC1 signaling branch by Yuefang Liu, Shujun Gao, Zhanghui Li, Lei Yin, Shiyao Ge, Yangjing Zhao, Hui Wang, Bing Wan, Qixiang Shao

“…Abstract Background and objective Hyperinflammatory response in early stage of sepsis was the key factor leading to multi-organ injury. …”
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Effect of polystyrene micro/nanoplastics on mesenchymal phenotypic transformation in testicular Sertoli cells by CAI Jing, WEN Yixian, ZHANG Huilian

“…Objective‍　‍To investigate the effects and potential mechanisms of polystyrene micro/nanoplastics (PS-MNPs) on testicular Sertoli cells. …”
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Mechanisms and network pharmacological analysis of Yangyin Fuzheng Jiedu prescription in the treatment of hepatocellular carcinoma by Yuqing Xie, Fengna Yan, Xinhui Wang, Lihua Yu, Huiwen Yan, Qing Pu, Weihong Li, Zhiyun Yang

“…Abstract Objective To identify the key drugs of Yangyin Fuzheng Jiedu prescription (YFJP) and investigate their therapeutic effects against hepatocellular carcinoma (HCC) and the potential mechanism using network pharmacology. …”
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Identification of Clusters in a Population With Obesity Using Machine Learning: Secondary Analysis of The Maastricht Study by Maik JM Beuken, Melanie Kleynen, Susy Braun, Kees Van Berkel, Carla van der Kallen, Annemarie Koster, Hans Bosma, Tos TJM Berendschot, Alfons JHM Houben, Nicole Dukers-Muijrers, Joop P van den Bergh, Abraham A Kroon, Iris M Kanera

“…For cluster 3 (n=1149), the most significant continuous variable was overall higher cognitive functioning (mean 0.2349, SD 0.5702 vs mean –0.3088, SD 0.7212; P<.001), and educational level was the most significant categorical variable (P<.001). …”
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The light-harvesting chlorophyll a/b-binding proteins of photosystem II family members are responsible for temperature sensitivity and leaf color phenotype in albino tea plant by Jing-Jing Ye, Xin-Yi Lin, Zi-Xian Yang, Ying-Qi Wang, Yue-Rong Liang, Kai-Rong Wang, Jian-Liang Lu, Peng Lu, Xin-Qiang Zheng

“…This study could provide a reference for further studies of the functions of the CsLHCB family and contribute to research on the mechanism of the albino in tea plant.…”
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Environmentally friendly synthesis of nanoporous silica materials using quercetin as a morphogenetic agent by A.R. Zare Hoseinabadi, E. Rafiei Taqanaki, S. Hafez Ghoran, A.M. Amani, H. Kamyab, A. Razmfarsa, E. Khalili, M. Yusuf, S. Rajendran

“…BACKGROUND AND OBJECTIVES: The synthesis of mesoporous silica nanoparticles using non-surfactant agents is gaining popularity owing to the easier purification and lower toxicity of this method compared to traditional surfactant-based ones. …”
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Validación de una encuesta de opinión sobre la eficacia de la simulación para participantes by Aida Camps-Gómez, Anna González-Fernández, Jennifer Morata-Serrano, Katherina M. Faundez-Inostroza, Carmen Gomar-Sancho, Marina Mateu-Capell

“…Abstract: Introduction: The participant's self-perception of a training is indicative of the achievement of its objectives, but the functionality and applicability of the instrument used to evaluate it must be submitted to a process of qualitative and quantitative analysis. …”
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Sodium arsenite influences proliferation and apoptosis in normal thyroid cells via modulation of ER-PI3K/AKT signaling pathway by Zhihong JIANG, Hongyun LI, Xiaowei MA, Yuanyan LAI, Jun WU

“…BackgroundRecent advances in understanding the toxic effects of inorganic arsenic have revealed that arsenic exposure impacts multiple endocrine organs, thereby altering their functions. However, the mechanisms underlying arsenic-induced thyroid injury remain unclear. …”
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Effectiveness of interventions for improving educational outcomes for people with disabilities in low‐ and middle‐income countries: A systematic review by Xanthe Hunt, Ashrita Saran, Howard White, Hannah Kuper

“…Such interventions involve a wide range of initiatives, from those focused on the individual level – such as teaching assistance to make mainstream classes more accessible to children with specific learning needs – to those which address policy or advocacy. Objectives The objectives of this review were to answer the following research questions: (1) What is the nature of the interventions used to support education for people with disabilities in LMICs? …”
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Growth Toxic Effects of Metal Nanoparticles on Bacillus subtilis and Vibrio parahaemolyticus by Shiyu CHEN, Bin XIA, Lin ZHU, Shuang LI, Qiufen LI, Xuemei SUN, Wei DAI

“…Based on the ecological roles and functions of these two bacteria in marine microbial communities, this study used B. subtilis and V. parahaemolyticus isolated from Bohai Bay as test organisms. …”
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Study on factors affecting fruit development of seedless ponkan cultivar Huagan No.4 by LIU Chenglang, LI Gangqiu, LI Shunxin, WEI Ranran, LU Yan, CHENG Chao, TANG Zheng, LIU Baoyan, YE Junli, CHAI Lijun, DENG Xiuxin, XIE Zongzhou

“…[Objective] Ponkan (Citrus reticulata Blanco.) is one of the main Mandarins cultivars in China. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…This ‘clinic model’ might operate at the single practice or cluster of practices level. Objective 6: potential National Health Service costs involved in the new pathway We were unable to meet this objective as originally intended. …”
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Regional Design by Verena Balz

“…A distance between actors with roles in these functions is required to enhance legitimacy and accountability. …”
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Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…Background High-risk patients with complex anorexia nervosa are managed in inpatient/day patient care, but re-admission rates are high, and new treatments are needed. Objective(s) To examine the effectiveness of a digital augmentation of aftercare (ECHOMANTRA). …”
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