Expression of ApoE and Spp1 in the cochlea and auditory cortex of age-related hearing loss mice by Yingxue Yuan, Junhong Zhang, Jingyi Zhao, Xiru Zhang, Zhixin Cao

“…GO and KEGG enrichment analyses revealed significant enrichment of differentially expressed proteins in functions and signaling pathways associated with neurodegenerative diseases and neurotransmission. …”
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An investigation into the frequency and risk factors of low back pain following surgical treatment of isolated calcaneal fractures by Dilek Bayraktar, Cengizhan Özgürbüz, Anıl Murat Öztürk, Salih Kemal Aktuğlu, Nadir Özkayın

“…Objective: This study aimed to determine the frequency of low back pain after calcaneal fractures treated with open reduction internal fixation (ORIF) and the risk factors that cause this condition. …”
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Differential involvement of neurotransmitter pathways in AD, bvFTD and MCI: Whole-brain MRI analysis by Ricardo Félix Morais, José Maria Sousa, Cemal Koba, Leon Andres, Tiago Jesus, Inês Baldeiras, Tiago Gil Oliveira, Isabel Santana

“…Background and objectives: Neurodegenerative diseases, including Alzheimer's disease (AD), mild cognitive impairment (MCI), and frontotemporal dementia (FTD), are a growing public health challenge, with dementia incidence projected to triple in the coming decades. …”
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Extracellular vesicle tissue factor and tissue factor pathway inhibitor are independent discriminators of sepsis-induced coagulopathy by Anna K. Tobiasch, Georg F. Lehner, Clemens Feistritzer, Andreas Peer, Birgit Zassler, Viktoria M. Neumair, Sebastian J. Klein, Michael Joannidis

“…Only EV-associated and functionally active TF and not TF antigen levels showed a predictive potential regarding DIC. …”
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Construction of a novel radioresistance-related signature for prediction of prognosis, immune microenvironment and anti-tumour drug sensitivity in non-small cell lung cancer by Yanliang Chen, Chan Zhou, Xiaoqiao Zhang, Min Chen, Meifang Wang, Lisha Zhang, Yanhui Chen, Litao Huang, Junjun Sun, Dandan Wang, Yong Chen

“…Background Non-small cell lung cancer (NSCLC) is a fatal disease, and radioresistance is an important factor leading to treatment failure and disease progression. The objective of this research was to detect radioresistance-related genes (RRRGs) with prognostic value in NSCLC.Methods The weighted gene coexpression network analysis (WGCNA) and differentially expressed genes (DEGs) analysis were performed to identify RRRGs using expression profiles from TCGA and GEO databases. …”
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Vitamin C, Sugar Content, Color Intensity and Some Physicochemical Properties of Watermelon and Orange Peels by Selvican Gökçe, İsa Arslan Karakütük, Memnune Şengül

“…Objective: Peels generated as waste during the consumption and processing of fruits and vegetables contribute to both nutritional losses and environmental pollution. …”
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Non-invasive urinary proteomic biomarkers for prognostic assessment in sepsis by Qingbo Zeng, Nianqing Zhang, Junjie Zeng, Lincui Zhong, Qingwei Lin, Longping He, Xiaomin Song, Jingchun Song

“…Abstract Early identification of the death risk of sepsis may improve short-term prognosis. The objective of this study was to identify urinary proteomic biomarkers and create a model to predict short-term outcomes in sepsis patients. …”
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MicroRNA-18b-5p Inhibits the Malignant Progression of Prostate Cancer Through Downregulating TRAF5 by Wang X, Yu X, Wang Y, Lian J, Li Z, Dong C, Song H, Zhang L, Zhang H, Wang Y

“…Herein, miR-18b-5p/TRAF5 axis-oriented exploration in PCa has been launched.Methods: miR-18b-5p and TRAF5 expression in PCa tissues and cells was detected by RT-qPCR. In-vitro experiments were conducted to investigate the biological functions of miR-18b-5p and TRAF5 in PCa cells. …”
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Longitudinal Network Relationships Between Symptoms of Deviant Peer Affiliation and Internet Gaming Disorder in Adolescents: Prospective Cohort Study by Tingting Gao, Fengtong Qian, Rui Li, Yimeng Lyu, Yingying Su

“…Targeted interventions could disrupt the cycle of maladaptive behavior by focusing on improving both peer and social functioning during critical developmental periods, ultimately preventing the exacerbation of these behavioral issues over time.…”
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Identification and expression characterization of apple β-tubulin gene family in apple by HUANG Huiling, WANG Yanxiang, WANG Yue, NING Qinqin, LI Ming, HAO Pengbo, CONG Liu, BAI Tuanhui, SHI Jiangli, JIAO Jian, WANG Miaomiao, LIU Yu, ZHAO Yujie, WAN Ran, SHEN Yawen, ZHANG Hengtao, ZHANG Kunxi, ZHENG Xianbo

“…[Objective] Microtubule is composed of α-and β-tubulin heterodimers. …”
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Pan-cancer analysis identified CD248 as a potential target for multiple tumor types by Li Guo, Yan Liao, Xuyang Zhang, Rongjuan Guo, Zheng Wang, Deqin Yang, Deqin Yang, Deqin Yang

“…ObjectiveTumors remain a major cause of death worldwide due to late-stage presentation and late diagnosis. …”
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Effect of SNORD113-3/ADAR2 on glycolipid metabolism in glioblastoma via A-to-I editing of PHKA2 by Zheng Cui, Xiaobai Liu, Tiange E, Hongda Lin, Di Wang, Yunhui Liu, Xuelei Ruan, Ping Wang, Libo Liu, Yixue Xue

“…However, the precise functions of snoRNAs and ADARs in glycolipid metabolism within GBM cells remain elusive. …”
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Early Digital Engagement Among Younger Children and the Transformation of Parenting in the Digital Age From an mHealth Perspective: Scoping Review by Nafisa Anjum, Md Mehedi Hasan, Nursat Jahan, Sheikh Iqbal Ahamed, Allison Garefino, Nazmus Sakib

“…This study provides valuable insights into improving obedience to healthy screen use and fostering a digital ecosystem where technology itself functions as an advocate of child progress, instead of an obligation.…”
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Variabilidad espacial y diaria del contenido de humedad en el suelo en tres sistemas agroforestales Spatial and daily variability of soil moisture content in three agroforestry sys... by Mariela Rivera Peña, Edgar Amézquita Collazos, Idupulapati Rao, Juan Carlos Menjivar Flores

“…The geo-statistical analysis showed that the random component of the spatial dependence was predominant over the nugget effect. The functions of semivariograms, structured for each variable were used to generate maps of interpolated contours at a fine scale. …”
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Impaired sensitivity to thyroid hormones is associated with increased body fat mass/muscle mass ratio (F/M) in the euthyroid population by Ying Li, Qianqian Zhang, Li Chen, Yue Wang, Qibao Ye, Wei Liu, Yan Liu, Guojuan Wang

“…Biochemical indexes including blood glucose, blood lipids, liver and kidney functions and thyrotropic hormones (THs) were detected. …”
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Effect of bile acids on digestion by O. O. Stremoukhov

“…Studying the effects of different bile acids in the body in recent years significantly increased the understanding of their physiological functions. The role of bile acids is to transfer to Striated border of enterocytes lipids in high micellar concentration and subsequent return them to the water layer in the molecular form. …”
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Short-term use of ceftriaxone sodium leads to intestinal barrier disruption and ultrastructural changes of kidney in SD rats by Wenli Zou, Yueming Liu, Wei Zhang, Bo Lin, Wei Shen, Yiwen Li, Qiang He, Juan Jin

“…Objective Antibiotic treatments are known to disturb gut microbiota, but their effects on the mucosal barrier and extraintestinal diseases are rarely discussed. …”
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A stratified therapeutic model incorporated with studies on regulatory B cells for elderly patients with newly diagnosed multiple myeloma by Wenjiao Tang, Yan Li, Zhongqing Zou, Jian Cui, Fangfang Wang, Yuhuan Zheng, Li Hou, Ling Pan, Bing Xiang, Hong Chang, Li Zhang, Ting Niu

“…Abstract Objective Despite the availability of new agents, elderly patients with multiple myeloma (MM) usually present with poor outcomes due to the heterogeneity of disease conditions, especially immune deficiency. …”
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Modified transforaminal epidural steroid injection combined with pulsed radiofrequency: an effective treatment measure for lumbar radiculopathy by Qi Yan, Xianggu Zhong, Jiarong Li, Leyu Zhao, Junjie Niu, Dawei Song, Jinning Wang, Yun Teng, Tianyi Wu, Xiao Sun, Rui Chen, Shuangfei Wang, Jun Zou

“…Consequently, clinicians require an expedited and efficacious approach to address radicular discomfort resulting from lumbar radiculopathy and promptly reinstate the patient's normal functionality.ObjectivesThis study seeks to assess the effectiveness of a modified transforaminal epidural steroid injection (TFESI) in conjunction with pulsed radiofrequency (PRF) for treating lumbar radiculopathy using a retrospective analysis.MethodsOur study examined patients with unilateral lower limb radicular pain persisting for three months or more due to LDH, in whom conservative therapies were ineffective, from January 1, 2023, to October 31, 2023. …”
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Cardioprotective Effect of Growth Differentiation Factor 15 Against Isoproterenol-Induced Cardiomyocyte Apoptosis via Regulation of the Mitochondrial Fusion by Yan Zhang, Zhu Mei, Xiaodong Jia, Haixu Song, Jing Liu, Xiaoxiang Tian, Tianyu Xu, Xiaoxia Fu

“…Abstract. Objective:. Pressure overload-induced myocardial apoptosis is a critical pathologically initiated process leading to heart failure (HF). …”
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