Comparison of self-stigma and quality of life in patients with depressive disorders and schizophrenia spectrum disorders – a cross-sectional study by Holubova M, Prasko J, Matousek S, Latalova K, Marackova M, Vrbova K, Grambal A, Slepecky M, Zatkova M

“…Michaela Holubova,1,2 Jan Prasko,1 Stanislav Matousek,1 Klara Latalova,1 Marketa Marackova,1 Kristyna Vrbova,1 Aleš Grambal,1 Milos Slepecky,3 Marta Zatkova3 1Department of Psychiatry, Faculty of Medicine and Dentistry, Palacky University Olomouc, University Hospital Olomouc, Olomouc, 2Department of Psychiatry, Hospital Liberec, Liberec, Czech Republic; 3Department of Psychology Sciences, Faculty of Social Science and Health Care, Constantine the Philosopher University in Nitra, Nitra, Slovak Republic Background: The views of one’s self-stigma and quality of life (QoL) in patients with schizophrenia and depressive disorders are significant subjective notions, both being proven to affect patient’s functioning in life. The objective of this study was to investigate the QoL and self-stigma in connection with demographic factors and compare the two groups of patients in terms of those variables. …”
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Aspirin Exerts Its Antitumor Effect in Esophageal Squamous Cell Carcinoma by Downregulating the Expression of ATAD2 and KIF4A by Man Zhang, Zhenzhen Ren, Xianzeng Wang, Cong Liu, Zhaoyang Zheng, Junwei Zhao, Hongchun Liu

“…Objective. To investigate the expression of ATPase family AAA domain-containing protein 2 (ATAD2) and kinesin family member 4A (KIF4A) in esophageal squamous cell carcinoma (ESCC) tissues and their association with clinicopathological features and to explore the role of ATAD2 in regulating KIF4A expression and biological functions in ESCC cells and the effect of aspirin on their expression. …”
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PTGS2 affects prognosis of colon cancer patients through regulation of cell proliferation and antioxidant capacity by HE Yangzhige, JIANG Xu, ZHANG Zhiwen, GONG Yiyi

“…Objective To investigate the effect and potential molecular mechanism of PTGS2 on the prognosis of colon cancer patients. …”
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LncRNA SNHG15 targets miR-200a-3p affects the proliferation, apoptosis, migration, and invasion of cervical cancer cells by Songtao Han, Yajuan Qin, YuJiao He, Ming Li, Jing Ma, Ning Luo, Yishan Huo, Xinling Meng, Yunmei Liu

“…SNHG15 has been found and proven to have important functions in many cancers. Related studies have shown that miR-200a-3p plays an important role in tumor development. …”
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The amino acid composition of Polygonum hydropiper L. and Polygonum persicaria L. herbs of Ukrainian flora by I. A. Lukina, O. V. Mazulin, H. P. Smoilovska, H. V. Mazulin, I. N. Shevchenko

“…Plant amino acids play an important role in the functioning of various systems and organs of the human body and are characterized by distinct pharmacological properties, as well as contribute to more rapid absorption and potentiate the effect of other biologically active compounds present in plants. …”
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The Effectiveness of Acth Therapy According to Etiology in Patients with West Syndrome and Its Long-Term Effects on Bone Mineral Metabolism and Adrenal Pathway by Mesut Güngör, Mine Düzgöl, Hülya Maraş Genç, Emek Uyur Yalçın, Filiz Mine Çizmecioğlu Jones, Bülent Kara

“…Objective: West syndrome is the most common infantile epileptic encephalopathy, and ACTH or oral corticosteroids are frequently used in its treatment. …”
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Review and Comparative Evaluation of Mobile Apps for Cardiovascular Risk Estimation: Usability Evaluation Using mHealth App Usability Questionnaire by Adrijana Svenšek, Lucija Gosak, Mateja Lorber, Gregor Štiglic, Nino Fijačko

“…Based on the apps’ characteristics (ie, developed for health care professionals or patient use) and their functions (single or multiple CVD risk calculators), we conducted a descriptive analysis. …”
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Impact of pancreatic cell-engineered constructs on the islet apparatus in recipient rats with type I diabetes mellitus by N. V. Baranova, L. A. Kirsanova, G. N. Bubentsova, A. S. Ponomareva, A. O. Nikolskaya, Yu. B. Basok, V. I. Sevastianov

“…Morphological examination of the pancreatic islet apparatus in the experimental animals revealed that implantation of the PCEC had a be- neficial effect on restoration of the recipient’s pool of functionally active beta cells, serving as a trigger for the regenerative process.…”
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Improving transparency in malaria programme funds: A business case for connected diagnostics in Kenya by Charlotte M. Dieteren, Emmanuel Milimo, Angela Siteyi, Shannen van Duijn, Leon Stijvers, Lilyana Dayo, Gregory Ganda, Tobias F. Rinke de Wit

“…Background: International vertical health financing programmes risk functioning in parallel with existing domestic funding in low- and middle-income countries (LMICs), leading to inefficient service delivery and concomitant poor health outcomes. …”
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Upregulation of Peripheral Blood NLRP3 and IL‐18 in Patients With Acute Kidney Injury in Sepsis and Its Clinical Significance by Jing Zhou, Yibin Ye, Zhipeng Chen, Yong Liu, Baozheng Wu, Haiping Huang

“…KEGG and GO analysis were used to identify enriched molecular functions and pathways. The study included 62 SA patients admitted to the Department of Intensive Care Medicine of our hospital from February 2021 to June 2022, including 34 non‐AKI cases and 28 AKI cases, and 25 healthy volunteers were used as the control group. …”
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Psychometric Hepatic Encephalopathy Tests and Electroencephalogram Results Among Cirrhotic Patients by Alaa Aboud Mohamed, Mostafa M. Elkholy, Ola O. Mangoud, Ahmed R. N. Ibrahim, Marwa O. Elgendy, Ali M. Abdel Fattah

“…<i>Background and Objectives</i>: Patients with cirrhosis who seem normal during physical examinations may still have abnormalities in their electroencephalogram (EEG) or show pathological results in neuropsychological tests. …”
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Developing Heterogeneous Porous 3D-Printed SiO₂-Pd-K₂SiO₃ Monolithic Catalyst via Surface MOF Growth and Pyrolysis for the Synthesis of Antitumoral... by Alexandrina Druta, Rania Bouhmala, Teqwa Ragdi, Mariangel Luna, Manuel Bañobre-López, Christian F. Masaguer, Manuel Amorín, Silvia Barbosa, Pablo Taboada, Alberto Coelho

“…<b>Background/Objectives</b>: The isatin nucleus is a privileged scaffold in drug discovery, particularly due to its proven relevance in anticancer research. …”
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Genome-wide association study identifies loci and candidate genes for root traits in rice grown in Brazil by Gabriel Brandão das Chagas, Latóia Eduarda Maltzahn, Josiane Vargas de Oliveira Maximino, Viviane Kopp da Luz, Ariano Martins de Magalhães Junior, Antonio Costa de Oliveira, Luciano Carlos da Maia, Camila Pegoraro

“…Root system is a key trait for rice yield, as it is responsible for water uptake, absorption, transportation of nutrients from soil, and other vital functions. Root dry weight (RDW) and root length (RL) are related to crop yields. …”
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A novel GJA3 mutation causing autosomal dominant congenital perinuclear cataracts by Yanan Zhu, Nanlan Li, Ke Yao, Wei Wang, Jinyu Li

“…Abstract Objective To identify the cause of congenital perinuclear cataracts in a Chinese family and its underlying mechanism. …”
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Protective Effect of Low-molecular-weight Fucoidan on Lead-induced Oxidative Damage in HepG2 Cells Based on Cellular Metabolomics by Fan YU, Na LI, Yingying GUO, Xinyue DAI, Wenjia ZHU, Lin YAO, Yanhua JIANG, Lianzhu WANG

“…Objective: This study aimed to investigate the protective effects and metabolic regulatory mechanisms of low-molecular-weight fucoidan sulfate (F1) on lead (Pb)-induced oxidative damage in HepG2 cells. …”
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Analysis on related risk factors for cardiocerebral vascular diseases in patients with diabetic kidney disease by ZHANG Zhi-xu, GAO Ai-qing, RAO Xiao-pang

“…Objective To investigate the epidemiology and related risk factors for cardiocerebral vascular diseases in patients with diabetic kidney diseases（DKD）.Methods A total of 800 patients with DKD hospitalized in Chengyang District People’s Hospital of Qingdao from January 2016 to December 2017 were enrolled in this study.Based on complications of cardiocerebral vascular diseases, the patients were divided into the cardiocerebral vascular disease group（n=558） and group without cardiocerebral vascular diseases（n=242）.The general information,including gender,age,body mass,height,systolic blood pressure（SBP）, diastolic blood pressure（DBP）,drinking history and smoking history, and laboratory test indicators, including fasting blood glucose（FBG）, glycosylated hemoglobin（HbA1 C）, liver and kidney functions, total cholesterol（TCH）, triglyceride（TG）, low density lipoprotein cholesterol（LDL-C）, high density lipoprotein cholesterol（HDL-C）, Lipoprotein A（Apoa）,parathyroid hormone（PTH）, C-reactive protein（CRP）, hemoglobin（Hb）, white blood cells（WBC）, brain natriuretic peptide（BNP）, urinary microalbumin/urinary creatinine ratio（UACR） and serum β₂-microglobulin（β₂-MG）were detected. …”
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Gestión de los Colegios Profesionales de Educación Física y Deporte desde una perspectiva interna (Management of Professional Colleges of Physical Education and Sport from an inte... by Roberto Silva Piñeiro, Jorge Fernando García Unanue

“…Objectives. To describe the current situationt of a part of the internal management of the COLEF. …”
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Blue Light and Green Light Fundus Autofluorescence, Complementary to Optical Coherence Tomography, in Age-Related Macular Degeneration Evaluation by Antonia-Elena Ranetti, Horia Tudor Stanca, Mihnea Munteanu, Raluca Bievel Radulescu, Simona Stanca

“…Despite identical acquisition times and nearly indistinguishable workflows, G-FAF is notably underutilized in clinical practice. <b>Objectives:</b> This narrative review critically compares green and blue FAF in terms of their diagnostic utility relative to OCT, with a focus on lesion detectability, macular pigment interference, and clinical decision-making in retinal disorders. …”
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Bovine milk consumption affects the transcriptome of porcine adipose stem cells: Do exosomes play any role? by Katherine Swanson, Jimmy Bell, David Hendrix, Duo Jiang, Michelle Kutzler, Brandon Batty, Melanie Hanlon, Massimo Bionaz

“…Of the 900 identified miRs in porcine plasma exosomes, only 3 miRs were differentially abundant between the two groups and could target genes associated with neuronal functions. We could not detect exosomal miRs or mRNA transfer from milk to porcine-circulating plasma exosomes. …”
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Association of DGAT1 and POU1F1 Gene Polymorphisms With the Milk Traits in the Cross‐Bred Hamdani Sheep Bred Under Extensive Management by Ali Osman Turgut, Davut Koca, Mehmet Eroğlu

“…POU1F1 affects pituitary gland functions and hormone secretion, indirectly impacting milk production. …”
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