Gallium-68-labeled fibroblast activation protein inhibitor-46 PET in patients with resectable or borderline resectable pancreatic ductal adenocarcinoma: A phase 2, multicenter, sin... by Aashna Karbhari, Sherly Mosessian, Kamaxi H Trivedi, Frank Valla, Mark Jacobson, Mark J Truty, Nandakumar G Patnam, Diane M Simeone, Elcin Zan, Tracy Brennan, Hongli Chen, Phillip H Kuo, Ken Herrmann, Ajit H Goenka

“…Histopathology and FAP immunohistochemistry (IHC) of initial diagnostic biopsy and resected tumor samples will serve as the truth standards. Primary objective is to assess the sensitivity, specificity, and accuracy of [68Ga]FAPI-46 PET for detecting FAP-expressing CAFs. …”
Get full text

Translocation of probiotics via gut–lung axis enhanced pulmonary immunity of weaned piglets exposed to low concentrations of ammonia by Jiajun Yang, Jing Wang, Peng Shang, Zongliang Liu, Bo Zhang, Dongsheng Yang, Hao Zhang

“…Objective: Lactobacillus salivarius is a probiotic bacteria strain in human and animal diets. …”
Get full text

Reference Whole Genome Sequence Analyses and Characterization of a Novel <i>Carnobacterium maltaromaticum</i> Distinct Sequence Type Isolated from a North American Gray Wolf (<i>Ca... by C. Cristoph Klews, Jessika L. Bryant, Jennifer McCabe, Ariel N. Atchley, Thomas W. Cousins, Maya Barnard-Davidson, Mark R. Ackermann, Michael Netherland, Nur A. Hasan, Peter A. Jordan, Evan S. Forsythe, Patrick N. Ball, Bruce S. Seal

“…We hypothesize that bacteria isolated from free-ranging animals could potentially be useful for practical applications. To meet this objective a Gram-positive bacterium was isolated from the gastrointestinal (GI) tract of a Gray Wolf (<i>Canis lupus</i>) using Brucella broth with hemin and vitamin K (BBHK). …”
Get full text

Understanding the Occurrence and Fate of Atmospheric Microplastics and Their Potential Risks to Human Health: Protocol for a Cross-Sectional Analysis by Shaikh Sharif Hasan, Abdus Salam, Mohammad Moniruzzaman, Md Aynul Bari, Nirupam Aich, Farjana Jahan, Mahbubur Rahman, Zubayer Islam, Md Humayun Kabir, Md Aftab Ali Shaikh, Rubhana Raqib, Sarker Masud Parvez

“…Human exposure will be assessed by detecting the metabolites of bisphenol and phthalates from urine samples using liquid chromatography–tandem mass spectrometry and thoroughly evaluating endocrine, reproductive, respiratory, and renal functions. …”
Get full text

Bone mineral density in patients with early axial spondyloarthritis by E. E. Gubar, T. V. Dubinina, A. D. Demina, O. A. Rumyantseva, M. M. Urumova, S. V. Shubin, A. A. Godzenko, A. V. Smirnov, S. I. Glukhova, Sh. F. Erdes

“…Objective: to study bone mineral density (BMD) of the lumbar spine (LS) and femoral neck (FN) in patients with early axial spondyloarthritis (SpA) and to reveal its association with inflammatory disease activity.Subjects and methods. …”
Get full text

Lung Pathology in Antiphospholipid Syndrome by T. M. Reshetnyak, S. G. Radenska-Lopovok, Ye. N. Aleksandrova, L. V. Kondratyeva, I. B. Shtivelband, A. A. Novikov, E. S. Mach, Ye. L. Nasonov

“…Functional lesions of organs depend on the size of a diseased vessel and frequently require the use of intensive therapy methods. …”
Get full text

Effects of Walnut Protein Peptides on Promotion of White Adipose Tissue Browning and Prevention of Obesity by Yankun FU, Yuzheng CAI, Zhiqiang FENG, Siru CHEN, Tianlin WANG, Lianjun SONG, Tiange LI

“…Objective: The aim of this study was to investigate the effect of walnut protein peptides (WPP) on the promotion of white adipose tissue (WAT) browning to prevent obesity. …”
Get full text

Role of ferroptosis in acute cadmium-induced liver injury in mice by YIN Qizi, TANG Yuting, ZHANG Saijun, GUO Siyu, LI Jing, WANG Ziyue, JI Yanli

“…Objective To investigate the role of ferroptosis in acute liver injury induced by cadmium (Cd) exposure in mice. …”
Get full text

Delta opioid peptide [D-ala2, D-leu5]-Enkephalin’s ability to enhance mitophagy via TRPV4 to relieve ischemia/reperfusion injury in brain microvascular endothelial cells by Xiaoyu Chen, Ran Zhang, Bing Shen, Yang Fang, Zhongfang Deng, Lingchao Kong, Jizheng Guo, Lesha Zhang

“…These protective effects of DADLE can be blocked by a TRPV4 inhibitor HC067047 or RNAi of TRPV4.Conclusion DADLE can promote mitophagy in BMECs through TRPV4, improving mitochondrial function and relieving I/R injury.…”
Get full text

Effector Responses Induced by Pattern Recognition Receptors (PRRs) for Disease Protection by L. Chi, Ya. Chi

“…Pattern Recognition Receptors (PRRs) represent fundamental components of the innate immune system responsible for detecting pathogenassociated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). …”
Get full text

Diagnosis and treatment of 23 cases of acute nephritis syndrome with lung injury by 张媛媛, 袁发焕

“…Objective To study the etiology, clinical characteristics, treatment and prognosis of Acute nephritis syndrome with lung injury, so as to improve identification and clinical diagnosis and treatment levels of this disease. …”
Get full text

Ginkgo biloba extract alleviates oxygen and glucose deprivation/reperfusion injury in cardiac microvascular endothelial cells by regulating NF-κB and CHOP signaling pathways throug... by Mukaddas ABDURAHMAN, Zhenyang GUO, Junbo GE, Hua LI

“…The expressions of PERK/eIF2α/CHOP, nuclear factor kappa B (NF-κB), and endothelial cell function markers were detected by Western blotting. …”
Get full text

Assessment of Mean Platelet Volume in Children with Celiac Disease on a Gluten-Free Diet by Meltem Cömert, Ersin Sayar, Meltem Gümüş, Ahmet Sert

“…Mean platelet volume (MPV) is a marker of platelet activation and function, and is considered a marker of inflammation. …”
Get full text

Investigation of the expression of the C-terminal cross-linking telopeptide of type I collagen (CTXI) in saliva during early and delayed loading of dental implants by Dania Hamid, Shaheen Ahmed, Abdul Hafeez Shaikh, Sadaf Nisar, Raheel Memon, Samreen Malik

“…The intervention involved functional loading of the implants according to the assigned group. …”
Get full text

The role and mechanism of CLEC7A in regulating PD-L1 to promote ovarian cancer growth by CHEN Yao, SUN Sibai, XU Jun, HE Jie

“…Objective To elucidate the role of C-type lectin domain family 7 member A （CLEC7A） in high-grade serous ovarian carcinoma （HGSOC） and its underlying mechanisms. …”
Get full text

American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score: a study protocol for the translation and validation of the Dutch language version by Cornelis H Van der Vlies, Esther M M van Lieshout, Michael H J Verhofstad, Duncan E Meuffels, A Siebe de Boer, Wim E Tuinebreijer, P Ted Den Hoed

“…A research physician or research assistant will complete the AOFAS Ankle-Hindfoot Score-DLV based on interview for the subjective part and a physical examination for the objective part. In addition, patients will be asked to complete the Foot Function Index (FFI) and the Short Form-36 (SF-36). …”
Get full text

Development of the ultrasonic sensor based modification coordination test device. by Widiastuti Widiastuti, Muhamad Syamsul Taufik, Yasep Setiakarnawijaya, Kuswahyudi Kuswahyudi, Muhammad Zulqarnain Mohd Nasir, Hendro Wardoyo, Karisdha Karisdha, Adi Wijayanto, Sunanto Sunanto, Nur Ahmad Muharram, Heni Yuli Handayani, Abdul Hafidz, Rivan Saghita Pratama, Septyaningrum Putri Purwoto

“…The placement of each LED depends on the user's needs. The function of the sensor is to detect objects around the sensor. …”
Get full text

MTHFD2-mediated redox homeostasis promotes gastric cancer progression under hypoxic conditions by Hai-Yu Mo, Ruo-Bing Wang, Meng-Yao Ma, Yi Zhang, Xin-Yu Li, Wang-Rong Wen, Yi Han, Tian Tian

“…Objectives: Cancer cells undergo metabolic reprogramming to adapt to high oxidative stress, but little is known about how metabolic remodeling enables gastric cancer cells to survive stress associated with aberrant reactive oxygen species (ROS) production. …”
Get full text

Evaluation of immune response to hepatitis B vaccine and its determinants among immunized anti-HBc-negative children in Ethiopia: A community-based cross-sectional study by Adane Adugna, Desalegn Abebaw, Mohammed Jemal

“…Generalized linear models with a Poisson distribution, log link function, and robust standard errors were used for multivariable analysis, with 95 % confidence intervals. …”
Get full text

Daily rhythms of glucose, insulin, and nonesterified fatty acid responses to an intravenous glucose tolerance test in dairy cows by Anay D. Ravelo, Cesar Matamoros, Kevin J. Harvatine, Isaac J. Salfer

“…A zero-amplitude test was used to determine the fit of a 24-h cosine function and cosinor rhythmometry was used to determine the amplitude and acrophase of the 24-h rhythm. …”
Get full text