Comorbidity Between Hikikomori and Autistic Traits May Be Identified as a Phenotypical Presentation Characterized by Greater Severity by Liliana Dell’Osso, Benedetta Nardi, Dario Muti, Chiara De Felice, Valeria Tognini, Francesca Parri, Federico Giovannoni, Filippo Del Grande, Chiara Bonelli, Gabriele Massimetti, Stefano Pini, Andrea Fiorillo, Barbara Carpita

“…<b>Objectives</b>: Hikikomori is a condition characterized by extreme social withdrawal, functional impairment, and mental distress, which has gained increasing recognition worldwide. …”
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Coping Styles and Defense Mechanisms in Healthy Young Adults—Correlations with tPA-BDNF Pathway by Julia Pilecka, Jedrzej Wojciechowski, Weronika Bargiel, Maria Terczynska, Przemyslaw Zakowicz, Dawid Bojarski, Karolina Wasicka-Przewozna, Maria Skibinska

“…Correlations of DSQ-40 scores with BDNF, proBDNF, MMP-9, and total serpin E1/PAI-1 were detected. Conclusions: Our findings indicate that there are functional associations between the proteins we studied and various coping styles, as well as mature, immature, and neurotic defense mechanisms.…”
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Case Report: Prolonged survival in Schinzel–Giedion syndrome featuring megaureter and de novo SETBP1 mutation by Glenda M. Beaman, Glenda M. Beaman, Benjamin W. Jarvis, Anju Goyal, David J. B. Keene, Max Cervellione, Filipa M. Lopes, Kay A. Metcalfe, Adrian S. Woolf, William G. Newman, William G. Newman

“…SETBP1 may drive the functional differentiation of the human fetal ureter.…”
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A Systematic Search for Candidate Supermassive Black Hole Binaries Using Periodic Mid-infrared Light Curves of Active Galactic Nuclei by Di Luo, Ning Jiang, Xin Liu

“…Analyzing a parent sample of 48,932 objects selected from about half a million AGNs, we have identified 28 candidate periodic AGNs with periods ranging from 1268 to 2437 days (in the observer frame), by fitting their WISE light curves with sinusoidal functions. …”
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CME Velocity Field Calculation Model Based on an Unsupervised Transformer Optical Flow Network by Qingyang Chen, Hong Lin, Zhenping Qiang, Hui Liu, Kaifan Ji, Zhenhong Shang

“…Most OF calculations are applied to the motion of labeled rigid objects and are not suitable for velocity detection of high-energy particles, such as in a coronal mass ejection (CME). …”
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Resveratrol Increases Cisplatin Sensitivity in Pancreatic Cancer Cells by Modulating Dihydroorotatede Hydrogenase-Mediated Ferroptosis by ZHENG Yanxia, LÜ Siyi, LI Tingting, DING Yusong

“…The fluorescent probe JC-1 was used to detect mitochondrial membrane potential (MMP) to explore the changes of mitochondrial function in cells. …”
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An Innovative Bio-Vehicle for Resveratrol and Tocopherol Based on Quinoa 11S Globulin—Nanocomplex Design and Characterization by Alejandra J. Rubinstein, Guadalupe Garcia Liñares, Valeria Boeris, Oscar E. Pérez

“…Nanocomplexes, which possess immense potential to function as nanovehicles, can link diverse ligand compounds. …”
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Puerarin alleviates renal ischemia/reperfusion injury by inhibiting apoptosis and endoplasmic reticulum stress via Nrf2/HO-1 pathway by Jingsong Wang, Qingyuan Zheng, Jun Jian, Xiuheng Liu, Zhiyuan Chen, Shanshan Wan, Lei Wang

“…Immunohistochemistry, immunocytochemistry, and Western blot analysis were used to detect the protein associated with apoptosis and endoplasmic reticulum stress.Results: Puerarin could improve renal function and attenuate tissue structural damage after renal I/R. …”
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The Mobile Complex of Chemical Control as the Basis of Technical Equipment of the Mobile Diagnostic Group of the 33 Central Scientific Research Test Institute of the Ministry of De... by V. A. Inozemtsev, A. K. Zhokhov, A. Yu. Boyko, A. S. Samorodov, A. V. Zhidyaev, A. A. Braginets

“…The complex is capable of detecting both low-hazard and emergency concentrations of practically all known toxic chemicals in various samples, and identifying these substances in environmental objects.…”
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Gamified mHealth System for Evaluating Upper Limb Motor Performance in Children: Cross-Sectional Feasibility Study by Md Raihan Mia, Sheikh Iqbal Ahamed, Samuel Nemanich

“…We developed MoEvGame, a mobile health (mHealth) gamification software system for the iPad, as a potential advanced technology to assess UL motor functions. ObjectiveThis feasibility study examines whether MoEvGame can assess children’s whole-limb movement, fine motor skills, manual dexterity, and bimanual coordination. …”
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In vitro experimental study of NUDT1 promoting the proliferation of oral squamous cell carcinoma cells by GUO Haobing, LU Lili, HAO Yacui, ZHAO Bowen, GAO Yihan, PIAO Songlin

“…[Objective:] To investigate the effect of Nudix hydrolase 1 (NUDT1) on the proliferation of oral squamous cell carcinoma (OSCC) cells, and its mechanism of function was tentatively explored. …”
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Retinoic and ascorbic acids induce osteoblast differentiation from human dental pulp mesenchymal stem cells by Lina M. Escobar, José Daniel Escobar, Zita Bendahan, Jaime E. Castellanos

“…Previous studies have suggested an important role of retinoic acid (RA) and ascorbic acid (AA) in the stimulation of osteoblastic differentiation; however, the function of RA and AA in the osteogenic differentiation from human dental pulp (hDPSCs) remains unclear. …”
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394 Inclusion of cytomegalovirus viral Fc gamma receptors in a glycoprotein B protein subunit vaccine improves Fc-mediated effector responses by Claire Otero, Mackensie Gross, Savannah Herbek, Megan Connors, Philipp Kolb, Sallie Permar

“…Objectives/Goals: We hypothesized that adding cytomegalovirus (CMV) viral Fc gamma receptors (vFcγRs) to a glycoprotein B (gB) protein subunit vaccine would improve vaccine-elicited Fc mediated effector functions such as antibody dependent cellular phagocytosis (ADCP) and cytotoxicity (ADCC), over gB subunit alone. …”
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Pyroptosis-Mediator GSDMD in Plasma: A Potent Biomarker Lung Cancer Diagnosis and Prognosis Assessment by Liu X, Yu F, Ding N, Wei C, Cui Y, Huo L

“…This study aimed to evaluate the diagnostic efficacy of Gasdermin D (GSDMD) in lung cancer and explore its biological functions.Methods: A total of 114 lung cancer patients, 87 patients with pulmonary nodules, and 100 healthy controls were enrolled. …”
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Data Mining–Based Model for Computer-Aided Diagnosis of Autism and Gelotophobia: Mixed Methods Deep Learning Approach by Mohamed Eldawansy, Hazem El Bakry, Samaa M Shohieb

“…ObjectiveThis study aimed to develop a deep learning–based diagnostic system that integrates facial emotion recognition with validated questionnaires to detect gelotophobia in individuals with or without ASD. …”
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Serum Levels of Asymmetric Dimethylarginine and Apelin as Potential Markers of Vascular Endothelial Dysfunction in Early Rheumatoid Arthritis by Manuela Di Franco, Francesca Romana Spinelli, Alessio Metere, Maria Chiara Gerardi, Virginia Conti, Francesca Boccalini, Cristina Iannuccelli, Francesco Ciciarello, Luciano Agati, Guido Valesini

“…Objectives. Impaired endothelial function represents the early stage of atherosclerosis, which is typically associated with systemic inflammatory diseases like rheumatoid arthritis (RA). …”
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RESULTS OF LIFE’S QUALITY RESEARCH AT PATIENTS WITH GLOSSODYNIA by V.N. Kulygina, I. A. Dorosh

“…In component of physical health: physical functioning (PF), role-functioning due to physical condition (RPC), the intensity of pain (IP) and general health (GH), in psychological - vitality (PV), social function (SF), role functioning due emotional state (RES) and mental health (MH). …”
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Minimally Invasive Fetoscopic Resection of Life-Threatening Amniotic Band Constrictions in a Human Fetus at 22 + 2 Weeks of Gestation Complicated by Subtotal Chorioamniotic Separat... by Nadja Riehle, Oliver Nowak, Leila Messroghli, Samantha Wakerlin, Thomas Schaible, Thomas Kohl

“…At almost three years of age, the child remains healthy and demonstrates normal function of the formerly constricted leg. Conclusions: Our case shows that the combination of tested percutaneous fetoscopic techniques, high-risk obstetrics, and modern neonatology can overcome multiple obstacles in order to save a fetal patient stuck in a near-hopeless situation.…”
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Norepinephrine Enhances Aerobic Glycolysis and May Act as a Predictive Factor for Immunotherapy in Gastric Cancer by Yangyang Wang, Shuchang Wang, Qin Yang, Jun Li, Fengrong Yu, Enhao Zhao

“…We aimed to explore the function of neurotransmitters in gastric cancer and identify a suitable target to treat gastric cancer patients in the future. …”
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Minimally invasive technologies for surgical treatment of kidney cancer by S. A. Rakul, P. N. Romashchenko, K. V. Pozdnyakov, N. A. Maistrenko, R. A. Eloev

“…The OBJECTIVE was to analyze the developmental trends, possibilities and outcomes of applying minimally invasive technologies in surgical treatment for kidney cancer.METHODS AnD MATERIALS. …”
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