A Predictive Model of the HIV Infection Course by E. I. Veselova, G. D. Kaminskiy, K. A. Kocharyan, A. B. Peregudova, O. V. Lovacheva, A. G. Samoylova

“…A predictive model formula was generated using those factors: D = -5.288-0.001 CD8+1.342VL+0.08 HIV DNA. With discriminant function D>0.065, the patient has a high probability of RV after 12 months of ART; with D ≤0.065, the probability of RV is low. …”
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Predicting Social Frailty in Older Adults Using Fitbit-Derived Circadian and Heart Rate Biomarkers: Cross-Sectional Study by Hiroki Maekawa, Yu Kume

“…Standardized questionnaires were used to assess physical functions, cognitive functions, and social frailty, and based on the scores, the participants were categorized into 3 groups: robust, social prefrailty, and social frailty. …”
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The Protective Effect of Cx43 Protein-Mediated Phosphocreatine on Myocardial Ischemia/Reperfusion Injury by Chen-xi Wang, Jun-jun Guo, An-jie Di, Yu Zhu, Wei-min Han, An-ran Cheng, Cheng Li, Rui-chan Si, Tian-shu Lan, Ran Zhang, Hong-li Liu, Guo-liang Yan

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Designing a Logistic Regression Model for a Dataset to Predict Diabetic Foot Ulcer in Diabetic Patients: High-Density Lipoprotein (HDL) Cholesterol Was the Negative Predictor by Seyyed Amir Yasin Ahmadi, Razieh Shirzadegan, Nazanin Mousavi, Ermia Farokhi, Maryam Soleimaninejad, Mehrzad Jafarzadeh

“…Objectives. Although the risk factors for diabetic neuropathy and diabetic foot ulcer have been detected, there was no practical modeling for their prediction. …”
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Joint Optimization of the 3D Model and 6D Pose for Monocular Pose Estimation by Liangchao Guo, Lin Chen, Qiufu Wang, Zhuo Zhang, Xiaoliang Sun

“…To achieve joint optimization, this paper builds the objective function based on the minimization of the reprojection error. …”
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Development of a deep learning model to predict smoking status in patients with chronic obstructive pulmonary disease: A secondary analysis of cross-sectional national survey by Sudarshan Pant, Hyung Jeong Yang, Sehyun Cho, EuiJeong Ryu, Ja Yun Choi

“…Objective This study aims to develop and validate a deep learning model to predict smoking status in patients with chronic obstructive pulmonary disease (COPD) using data from a national survey. …”
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Construction of a myocardial and skeletal muscle-specific Cyr61 gene knockout mouse model by XU Diyan, ZHANG Wenli, ZUO Yidan, SU Zhen

“…The skeletal muscle function of Cyr61 knockout mice was evaluated and following related indicators in the myocardium and skeletal muscle were detected by Western blot: Aging (p53, p21),inflammatory response (TNF-α,IL-18,IL-1β),fibrosis (vimentin,TGF-β,α-SMA,COL1). …”
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Glutamate activates the MAPK pathway by inhibiting LPAR1 expression and promotes anlotinib resistance in thyroid cancer by Bin Liu, Ying Peng, Yanjun Su, Chang Diao, Liansheng Cha, Ruochuan Cheng

“…Methods Glutamate was used to treat TC cell lines and TC-anlotinib-resistant cell lines, and changes in cell function and effects on the expression of LPAR1 and MAPK pathway-related proteins were assessed. …”
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Investigating Glial Fibrillary Acidic Protein Expression and Cell Morphology in a Rat Brain Following Exposure to a Weak Electromagnetic Field and Nitric Oxide Modulation During De... by Stephanie M. Sissons, Nirosha J. Murugan, Blake T. Dotta

“…Background/Objectives: Nitric oxide (NO) and electromagnetic fields (EMFs) have been reported to influence central nervous system (CNS) function and organization. …”
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Inhibitory effects of Caveolin-1-m ediated atorvastatin on vasoconstriction of interlobar renal artery in SHR rats by XIE Xiao-ping, ZHANG Hai-jun, GUO Yi-bin, ZHANG Xi, CHANG Yao-ming, BAO Jun-xiang

“…Isometric force recording system was used to detect the vascular function. Western blotting was conducted toexamine the protein abundance of caveolin-1 or angiotensin Ⅱ type 1 receptor（ AT₁）. …”
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Effect of high and low flux hemodialysis on vascular endothelial cell growth factor and interleukin-1 beta levels in maintenance hemodialysis patients by WANG Wen-zheng, ZHANG Jin-ping, WANG Jia, YANG Xiao-ping

“…Objective To invesigate the effects of the different dialysis procedures on vascular endothelial growth factor(VEGF) and interleukin-1 beta(IL-1β) levels in maintenance hemodialysis(MHD) patients to provide a theoretical basis for a reasonable choice for dialysis,and for improving the prognosis of patients with hemodialysis.Methods From June 2012 to June 2014 in the Blood Purification Center of the First Affiliated Hospital of Shihezi University,32 patients with MHD were selected,including high flux hemodialysis group of 16 cases,and low flux hemodialysis group of 16 cases.The 16 healthy volunteers served as control group.Related biochemical indexes were determined,and ELISA was used to detect the plasma levels of VEGF and IL-1β.Results As compared with control group,the plasma VEGF level in patients with MHD was significantly increased(P<0.05),and that in HFHD group was significantly lower than in LFHD group(P<0.05).The single factor correlation analysis showed that plasma VEGF level was positively correlated with dialysis age,intact parathyroid hormone(iPTH),and low density lipoprotein(r= 0.65,0.605,and 0.284,P<0.05).As compared with control group,plasma IL-1β was significantly increased,and that was statistically reduced in HFHD group as compared with LFHD group(P<0.05).The single factor correlation analysis showed there was a negative correlation between IL-1β and age(r=-0.261,P<0.05),but a positive correlation between IL-1β with low density lipoprotein,dialysis age,iPTH and VEGF(r =0.274,0.722,0.658,and 0.783,P<0.01).Single factor correlation analysis showed that plasma VEGF and IL-lβ levels showed a positive correlation(r = 0.783,P<0.01).Conclusions As compared with LFHD,HFHD can reduce micro-inflammatory state in MHD patients and protect endothelial function more effectively,and improve the prognosis of patients.…”
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The Expression and Regulatory Role of lncRNA CRNDE in Ischemic Stroke by Yuan Cheng, Qiujun Lu, Yuanyuan Su, Runxi Xu, Shuqi Huang, Chong Yang, Yunhua Hao, Jun Yang

“…The role of lncRNA CRNDE in IS remains unclear. Objective This study focused on investigating the function of lncRNA CRNDE in IS. …”
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Exposure to house dust endotoxin and allergic sensitization in allergic and nonallergic children living in Adana, Turkey by Mustafa Yilmaz, Derya Ufuk Altintaş, Gülbin Bingöl-Karakoç, Ayfer Inal, Mehmet Kiliç, Zeynel Sütolukta, Seval Güneşer-Kendirli

“…These children attended the study center again to complete a detailed questionnaire and medical examination including skin prick test and pulmonary function test. Of these children, 65 had allergen sensitization. …”
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Upregulation of miR-152 inhibits proliferation and migration of human vascular smooth muscle cells induced by ox-LDL by ZHOU Jing, QU Miao

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Gestational age and neonatal brain microstructure in term born infants: a birth cohort study. by Birit F P Broekman, Changqing Wang, Yue Li, Anne Rifkin-Graboi, Seang Mei Saw, Yap-Seng Chong, Kenneth Kwek, Peter D Gluckman, Marielle V Fortier, Michael J Meaney, Anqi Qiu, GUSTO Study Group

“…<h4>Objective</h4>Understanding healthy brain development in utero is crucial in order to detect abnormal developmental trajectories due to developmental disorders. …”
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Oridonin relieves renal damage of diabetic rats through modulation of oxidative stress and lipid metabolism by WU Lan, BAO Li-ping, LI Ju-shuang, WU Xiao-yan

“…Objective To investigate the protective effect and mechanism of oridonin on kidney of diabetic rats. …”
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MicroRNA-221 protects myocardial contractility in myocardial ischemia/reperfusion injury through phospholamban. by Hongyu Li, Jimiao Qiu, Chang Liu, Guobing Yu, Danyu Wu, Yichun Chu, Kai Wang

“…<h4>Objective</h4>To investigate the effects and mechanisms of miRNA 221 on myocardial ischemia/reperfusion injury (MIRI) in mice through the regulation of phospholamban (PLB) expression.…”
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THE IMPACT OF FIXED DENTURES ON THE TISSUES OF THE ORAL CAVITY AND THE COURSE OF GASTROINTESTINAL DISEASES by V.Yu. Davydenko, H.M. Davydenko, Ye.S. Khilinich, B.Yu. Sylenko

“…The relevance of the work lies in the fact that orthopedic treatment not only eliminates aesthetic defects, restores the impaired function of the dentoalveolar system, but also has a significant preventive value for the prevention of gastrointestinal diseases. …”
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Letter and Word Processing in Developmental Dyslexia: Evidence from a Two-Alternative Forced Choice Task by Daniela Traficante, Pierluigi Zoccolotti, Chiara Valeria Marinelli

“…Background/Objectives: The present study aimed to investigate letter processing in children with dyslexia and typically developing readers as a function of the type of orthographic context. …”
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Incidence, complications and therapeutic evaluation of clinical hypothyroidism in different breeds of dogs by Gehad E. Elgalfy, Mohamed M. Ghanem, Mahmoud A. Y. Helal, Heba M. El-khaiat

“…Abstract Background Hypothyroidism is one of the most common endocrine disorders in dogs, that is caused by reduction in thyroxine hormone production. Objectives This study aimed to detect the incidence of clinical hypothyroidism among cases suffering from dermatological changes or obesity, investigate the complications in severely affected hypothyroid dogs and evaluate the response to levothyroxine treatment. …”
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