Triptolide protects against podocyte injury in diabetic nephropathy by activating the Nrf2/HO-1 pathway and inhibiting the NLRP3 inflammasome pathway by Chenlei Lv, Tianyang Cheng, Bingbing Zhang, Ke Sun, Keda Lu

“…Objectives Diabetic nephropathy (DN) is the most common microvascular complication of diabetes mellitus. …”
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Generation of Cas9 Knock-In <i>Culex quinquefasciatus</i> Mosquito Cells by Elizabeth Walsh, Tran Zen B. Torres, Brian C. Prince, Claudia Rückert

“…In comparison to the RNAi-mediated gene silencing of <i>dicer-2</i>, <i>argonaute-2b</i>, and <i>piwi5</i>, our Cas9/sgRNA approach showed an enhanced ability to detect antiviral effects. <b>Conclusions</b>: We propose that this cell line offers a new tool for studying gene function in <i>Cx. quinquefasciatus</i> mosquitoes that avoids the use of RNAi. …”
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Differences in efficacies of continuous renal replacement therapy and intermittent hemodialysis upon urinary levels of insulin-like growth factor binding protein 7，neutrophil gelat... by Wang Xiang, Zhang Zhi-min, Li Jian-guo, Song Ya-jun

“…Observation group underwent CRRT while control group had IHD. All cardiac function tests were completed and blood biochemical parameters detected during treatment. …”
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Prevalence and treatment tactics of nonspecific urinary tract infection in tuberculosis patients by Z. R. Rashidov, S. I. Azimov

“…When choosing a therapeutic tactic, it is necessary to take into account the presence of structural and functional changes in the urinary tract which reduce treatment efficacy.…”
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Eye movements in mild traumatic brain injury: Ocular biomarkers by Matthew A. McDonald, Helen V Danesh-Meyer, Samantha Holdsworth

“…There is an urgent need to identify an objective biomarker which can not only detect injury, but inform prognosis and recovery. …”
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THE PROBLEM OF OSTEOPOROSIS IN PATIENTS WITH RHEUMATOID ARTHRITIS by Irina Mikhailovna Marusenko, O Yu Barysheva, N N Vezikova

“…Objective. To estimate the frequency and degree of osteopenia and osteoporosis (OP) in patients with rheumatoid arthritis (RA) versus those in patients with osteoarthrosis (OA). …”
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Electromagnetic Imaging in Half-Space Using U-Net with the Iterative Modified Contrast Scheme by Chien-Ching Chiu, Ching-Lieh Li, Po-Hsiang Chen, Yen-Chun Li, Eng-Hock Lim

“…IMCS is an innovative inversion technique that utilizes contrast functions to improve the visibility of target regions and reconstruct the internal structure of objects. …”
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Cerebral Near-Infrared Spectroscopy as a Measure of Nociceptive Evoked Activity in Critically III Infants by Manon Ranger, Celeste C Johnston, Catherine Limperopoulos, Janet E Rennick, Adre J du Plessis

“…Due to the subtlety or absence of predictable, objective signs of pain in critically ill infants, health care professionals must often rely on observations of behavioural or nonspecific physiological signals. …”
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Alterations of static and dynamic changes in intrinsic brain activity and its relation to behavioral outcomes in subcortical ischemic stroke after one-month intervention by Yongxin Li, Jianping Wang, Maohua Yao, Yun Ran

“…To achieve this goal, we combined static and dynamic functional imaging indicators for the comprehensive analysis. …”
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Research on Interference Resource Optimization Based on Improved Whale Optimization Algorithm by Xuyi Chen, Mingxi Ma, Chengkui Liu, Haifeng Xie, Shaoqi Wang

“…In this problem, this paper establishes an interference resource optimization model with radar detection probability, interference effectiveness, and interference bandwidth utilization as the objective functions. …”
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Early Attrition Prediction for Web-Based Interpretation Bias Modification to Reduce Anxious Thinking: A Machine Learning Study by Sonia Baee, Jeremy W Eberle, Anna N Baglione, Tyler Spears, Elijah Lewis, Hongning Wang, Daniel H Funk, Bethany Teachman, Laura E Barnes

“…ObjectiveThis paper aims to identify participants at a high risk of dropout during the early stages of 3 web-based trials of multisession CBM-I and to investigate which self-reported and passively detected feature sets computed from the participants interacting with the intervention and assessments were most informative in making this prediction. …”
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Research review of digital modeling technologies with 3D spatial visualization for pipelines by Xin LIU, Shengwen TU, Yanfang HOU, Dong LIN, Jie SHU, Yu TANG

“…These developments have resulted in more comprehensive functionalities for visualization systems and improved operational and maintenance efficiency. …”
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Correlation between brain imaging features and cognitive impairment in end-stage renal disease patients based on susceptibility-weighted imaging by GU Liangrui, YAN Bicong, FANG Tonglei, WU Jinliang

“…Among those with cognitive impairment, the number of CMBs in the cortical and subcortical areas was significantly negatively correlated with cognitive function (r=-0.718, P=0.030).Conclusion·The number and distribution of CMBs detected by SWI in ESRD patients are associated with both the presence and severity of cognitive impairment. …”
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Photosynthetic pigments and phenolic potential of Rhodiola rosea L. from plant communities of different ecology and geography by Sergeeva Irina Yu., Zaushintsena Alexandra V., Bryukhachev Evgeniy N.

“…Therefore, food biotechnology requires new data on the photosynthetic potential of plants with good functional prospects. The research objective was to study the qualitative and quantitative profile of biologically active compounds of Rhodiola rosea L. harvested from various plant communities in order to define the potential of their extracts and minor compounds for food technologies. …”
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Optimization of Platelet-Rich Plasma Fraction Selection for Surgical Treatment of Macular Holes by V. N. Kazaykin, N. S. Demchenko, A. Yu. Kleimenov

“…Objective: based on clinical and morpho — functional analysis of retinal restoration and assessment of the cellular composition of platelet-rich plasma, to determine its optimal fraction for surgical treatment of macular hole. …”
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Accuracy of warm ischemia time measurement using a surgical intelligence software in partial nephrectomies: A validation study by Archan Khandekar, Joao G. Porto, Jean C. Daher, Pedro F. S. Freitas, Dotan Asselman, Maritza M. Suarez, Mark L. Gonzalgo, Dipen J. Parekh, Sanoj Punnen

“…Abstract Objectives The objectives of this study are to compare the accuracy of warm ischemia times (WITs) derived by a surgical artificial intelligence (AI) software to those documented in surgeon operative reports during partial nephrectomy procedures and to assess the potential of this technology in evaluating postoperative renal function. …”
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Growth and Form Trait Variation Analysis Among Different Clones of Michelia chapensis by Zhixi DENG, Baishuan LYU, Rong HUANG, Limin ZHOU, Runhui WANG, Li CHEN, Zhijun LAI, Jiaqi CHEN, Jie ZHU, Ruping WEI, Huiquan ZHENG

“…【Objective】The study was aimed at the screening of superior germplasmls of Michelia chapensis with an objective to lay a foundation of the selection and breeding project of this species.…”
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Assessment of Limb Imbalance in Professional Soccer Players by Adrián Moreno-Villanueva, Alejandro Soler-López, Jose Carlos Cuartero-Martínez, Jose Pino-Ortega

“…The FMS (Functional Motion Screen) test is inversely related to the performance in jump tests; thus, its combination can help to detect asymmetries in power generation. …”
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The Role of Anti-Interferon-α Autoantibodies in Severe COVID-19: Implications for Vaccination Prioritization by Xin Rong Lim, Shiyu Liu, Hwee Siew Howe, Khai Pang Leong, Elampirai Elangovan, Chiung-Hui Huang, Kok Ooi Kong, Bernard Yu Hor Thong, Shawn Vasoo, Bernard Pui Lam Leung

“…<b>Background/Objectives</b>: Neutralizing autoantibodies against type I interferons, particularly interferon-alpha (IFN-α), have been implicated in severe COVID-19 outcomes. …”
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Association between herbicide exposure and liver enzyme levels in a middle-aged and elderly population by Weiya LI, Zhuoya ZHAO, Xu CHENG, Jun AN, Shiyang ZHANG, Chengyong JIA, Meian HE

“…The liver is an important organ for the detoxification of environmental pollutants; however, studies on the association between herbicide exposure and liver function are limited.ObjectivesTo investigate the association between baseline serum herbicide levels and changes in liver enzyme levels and liver enzyme abnormalities over a 5-year period in middle-aged and older adults.MethodsThis study was based on a nested case-control population of type 2 diabetes established in the Dongfeng-Tongji cohort, with a total of 1388 subjects included in this study and followed up for 5 years. …”
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