Structure-Function Relationship of the Ryanodine Receptor Cluster Network in Sinoatrial Node Cells by Alexander V. Maltsev, Valeria Ventura Subirachs, Oliver Monfredi, Magdalena Juhaszova, Pooja Ajay Warrier, Shardul Rakshit, Syevda Tagirova, Anna V. Maltsev, Michael D. Stern, Edward G. Lakatta, Victor A. Maltsev

Subjects: Get full text

Generalizing Robust Control Barrier Functions From a Controller Design Perspective by Anil Alan, Tamas G. Molnar, Aaron D. Ames, Gabor Orosz

Subjects: “…Control barrier function…”
Get full text

Computational modeling of epidemiological count data using Non-Homogeneous Poisson Processes and functional data by Santiago Ortiz, Juan Esteban Chavarría, Henry Velasco

Subjects: “…Intensity Function…”
Get full text

Study of CdTe detector response functions using different MCNPX computational modeling detailing by A. M. Antunes, B. M. Mendes, P. L. Squair, M. S. Nogueira, A. T. Almeida-Jr, M. A. S. Lacerda

“…The spectra measured with cadmium telluride (CdTe) detectors show high spectral distortions that must be corrected by applying a mathematical algorithm along with the detector's response functions. Simplified computational modeling of the CdTe detector is generally used to obtain its response functions. …”
Get full text

Prediction of the 180 day functional outcomes in aneurysmal subarachnoid hemorrhage using an optimized XGBoost model by Weichong Zhou, Xingfu Liao, Hui Shi, Mingfeng Wang, Yunchong Xiao, Xilu Yu, Yilong Wu, YanYi Liu, Yin Peng, Hai Su

Get full text

Impaired cognitive function and decreased monoamine neurotransmitters in the DNAJC12 gene knockout mouse model by Shunan Wang, Ming Shen, Bo Pang, Bo Zhou, Yuan Yuan, Mei Lu, Xiangling Deng, Min Yang, Shufang Liu, Qiong Wang, Mei Xue, Qisheng Xia, Zhixin Zhang

“…Based on the patients’ mutation location, we established the first DNAJC12 gene knockout mouse model. The knockout mice exhibit hyperphenylalaninemia, impaired cognitive function, and decreased monoamine neurotransmitters. …”
Get full text

Agarose Hydrogels Enriched by Humic Acids as a Functional Model for the Transport of Pharmaceuticals in Nature Systems by Martina Klučáková, Petra Závodská

Get full text

Development and Verification of Prognostic Prediction Models for Patients with Brain Trauma Based on Coagulation Function Indexes by Lanjuan Xu, Tingting An, Chengjian Li, Xin Shi, Bo Yang

Get full text

A New Mathematical Model for Flank Wear Prediction Using Functional Data Analysis Methodology by Sonja Jozić, Branimir Lela, Dražen Bajić

“…Regression coefficients of the model are in the form of time dependent functions that have been determined through the use of functional data analysis methodology. …”
Get full text

Instantaneous Metabolic Energetics: Data-Driven Modeling Using Function-Based Surrogates and Gradient Boosting by Christopher Buglino, William Z. Peng, Stacy Ashlyn, Hyunjong Song, Howard J. Hillstrom, Joo H. Kim

“…A gradient-boosted machine-learning model was then trained on the surrogate functions’ outputs. …”
Get full text

Establishment and functional studies of a model of cardiomyopathy with cardiomyocyte-specific conditional knockout of Arhgef18 by Xiaoqiong Fu, Wenjing Yuan, Jiajin Li, Kun Wan, Mei Ge, Bo Pan, Tiewei Lu

Get full text

Computation of the Domain of Attraction for Suboptimal Immunity Epidemic Models Using the Maximal Lyapunov Function Method by Chang Phang, Yonghong Wu, Benchawan Wiwatanapataphee

“…We are concerned with the estimation of the domain of attraction (DOA) for suboptimal immunity epidemic models. We establish a procedure to determine the maximal Lyapunov function in the form of rational functions. …”
Get full text

Identification of methionine metabolism related prognostic model and tumor suppressive functions of BHMT in hepatocellular carcinoma by Wenli Liu, Kaiheng Hu, Yaqing Fu, Tianmin Zhou, Qingmei Zhong, Wu Wang, Yang Gui, Ping Zhang, Di Yao, Xiaohong Yang, Weifeng Zhu, Zhuoqi Liu, Daya Luo, Yingqun Xiao

“…In summary, this study innovatively provides first methionine metabolism-related prognostic model and unveils the tumor suppressive function of BHMT in HCC, providing potential mechanism by which BHMT exert its function.…”
Get full text

Counterfactual explanations of tree based ensemble models for brain disease analysis with structure function coupling by Shaolong Wei, Zhen Gao, Hongcheng Yao, Xiaoyu Qi, Mingliang Wang, Jiashuang Huang

“…Abstract Convergent evidence has suggested that the disruption of either structural connectivity (SC) or functional connectivity (FC) in the brain can lead to various neuropsychiatric disorders. …”
Get full text

Functional Test Scales for Evaluating Cell-Based Therapies in Animal Models of Spinal Cord Injury by Woon Ryoung Kim, Minjin Kang, Heejoo Park, Hyun-Joo Ham, Hyunji Lee, Dongho Geum

“…However, as there is no cure for the deficits produced by SCI, various therapeutic strategies have been examined using animal models. Due to the lack of standardized functional assessment tools for use in such models, it is important to choose a suitable animal model and precise behavioral test when evaluating the efficacy of potential SCI treatments. …”
Get full text

FANTASIA leverages language models to decode the functional dark proteome across the animal tree of life by Gemma I. Martínez-Redondo, Francisco M. Perez-Canales, Belén Carbonetto, José M. Fernández, Israel Barrios-Núñez, Marçal Vázquez-Valls, Ildefonso Cases, Ana M. Rojas, Rosa Fernández

“…Abstract Protein functional annotation is crucial in biology, but many protein-coding genes remain uncharacterized, especially in non-model organisms. …”
Get full text

Asymptotic Stability of a Rumor Spreading Model with Three Time Delays and Two Saturation Functions by Teng Sheng, Chunlong Fu, Xiaofan Yang, Yang Qin, Luxing Yang

“…In this article, a rumor spreading model with three time delays and two saturation functions is proposed. …”
Get full text

Immuno-enhancing effects of surimi products including functional ingredients in vitro and in vivo zebrafish model by Dong-Hyeon Kim, Heeseob Lee, Hye-Won Yang, You-Jin Jeon

Get full text

MIXED GEOGRAPHICALLY WEIGHTED REGRESSION (MGWR) WITH ADAPTIVE WEIGHTING FUNCTION IN POVERTY MODELING IN NTT PROVINCE by Petrus Kanisius Ola, Atiek Iriany, Suci Astutik

“…The study findings show that the MGWR model with an adaptive weighting function offers better estimates than the global regression and GWR models. …”
Get full text

Functional Prediction of Hypothetical Proteins from and Validation of the Predicted Models by Using ROC Curve Analysis by Md. Amran Gazi, Sultan Mahmud, Shah Mohammad Fahim, Mohammad Golam Kibria, Parag Palit, Md. Rezaul Islam, Humaira Rashid, Subhasish Das, Mustafa Mahfuz, Tahmeed Ahmeed

Get full text