Association of D-dimer to albumin ratio with adverse cardiovascular outcomes in ischaemic heart failure patients with diabetes mellitus: a retrospective cohort study by Xiaolong Lin, Jinghua Liu, Siyuan Chen, Qiuyu Li, Xiaowen Bo, Donghui Zhao, Qian Fan

“…The cumulative incidence functions, Cox regression, restricted cubic spline and receiver operating characteristic curves were used to determine the association between DAR and outcomes. …”
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A Discrete-Event Based Power Management System Framework for AC Microgrids by Paolo C. Erazo Huera, Thamiris B. de Paula, João M. T. do Amaral, Thiago M. Tuxi, Gustavo S. Viana, Emanuel L. van Emmerik, Robson F. S. Dias

“…A detailed step-by-step methodology is provided, which covers the entire process from defining discrete events, modeling microgrid components, synthesizing supervisory controllers, and realizing them in MATLAB (R2024b) Stateflow. …”
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PediaTrac V.3.0 protocol: a prospective, longitudinal study of the development and validation of a web-based tool to measure and track infant and toddler development from birth thr... by H Gerry Taylor, Renee Lajiness-O'Neill, Seth Warschausky, Alissa Huth-Bocks, Judith Brooks, Angela Lukomski, Trivellore Eachambadi Raghunathan, Patricia Berglund, Angela D Staples, Laszlo Erdodi, Stephen Schilling

“…Parameter estimates of our items and latent traits (eg, sensorimotor) will be estimated by theta using item response theory-graded response modelling. Participants also will complete legacy (ie, established) measures of development and caregiver health and functioning, used to provide evidence for construct (discriminant) validity. …”
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Surface charge modulation in metal-crosslinked sodium alginate-chitosan composite adsorbent: Optimized anionic-to-cationic polysaccharide component ratio for Cd and Cr removal from... by Aminat Mohammed Ahmed, Mhamed Berrada, Menbere Leul Mekonnen, Ayalew H. Assen, Ephriem Tadesse Mengesha, Redouane Beniazza, Kebede Nigussie Mekonnen, Youssef Belmabkhout

“…The Zr/Fe-SA/CS beads were characterized by FTIR, XRD, SEM-EDX, BET, and TGA to confirm that the polysaccharides were well incorporated and functionalized within the adsorbent. The composite beads were employed in batch mode for adsorptive removal of Cd2+ and Cr3+, offering the maximum uptakes of 77.88 mgCd2+/g and 66.36 mgCr3+/g. …”
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DATA 5.0—Data Acquisition, Translation & Analysis—a prospective urooncological data warehouse for the 21st century by Viktoria Schütz, Christine Geisler, Mathias Rath, Sarah Böning, Thomas Treber, Albrecht Stenzinger, Alexander Brobeil, Oliver Reinhard, Anette Duensing, Anette Duensing, Stefan Duensing, Stefan Duensing, Markus Hohenfellner, Magdalena Görtz

“…However, the transfer of existing data into a new environment proved to be technically challenging.ObjectiveTo migrate the existing data into a modern data warehouse (DATA 5.0) while maintaining data extraction functions. Additional requirements included FHIR connectivity, big data analyses and AI applications.MethodsTogether with SAP SE, DATA 5.0 was developed. …”
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EURAD state-of-the-art report: thermo-hydro-mechanical behaviour of clay buffers at high temperatures by María Victoria Villar, Katerina Cernochova, Jaime Cuevas, Antonio Gens, Natalia Gimeno, Caroline Graham, Jon Harrington, Vlastislav Kašpar, Stephan Kaufhold, Olivier Leupin, David Mašín, Jan Najser, Markus Olin, Heini Reijonen, Šárka Šachlová, Sergey Sayenko, Daniel Svensson, Jiri Svoboda, Gianni Vettese, Janne Yliharju, Borys Zlobenko

“…Given that being able to tolerate higher temperatures would have significant advantages, the work package HITEC of the EURAD project aimed at determining the influence of temperature above 100°C on buffer properties, trying to establish if the safety functions are unacceptably impaired. A synthesis of the state of knowledge on the thermo-hydro-mechanical and chemical behaviours of different buffer materials at different temperatures is presented, along with the progress made in this area during HITEC. …”
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Spatiotemporal analysis of Anopheles gambiae larval sites and malaria transmission in Djilakh, Central Senegal by Assane Ndiaye, Camille Morlighem, Aminata Niang Diène, Moussa Kane, Abdoulaye Diallo, Fassiatou Tairou, Mohamed Abderemane Nourdine, Pape Cheikh Sarr, Lassana Konaté, Ousmane Faye, Oumar Gaye, El Hadji Amadou Niang, Catherine Linard, Ousmane Sy

“…The correlation between malaria morbidity and functioning breeding sites varied throughout the rainy season, depending on the size and stability of the existing breeding sites. …”
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Single-nucleus RNA sequencing reveals the specific molecular signatures of myeloid cells responding to brain injury after microglial replacement by Xiao-Yi Xiong, Xiao-Yi Xiong, Xiao-Yi Xiong, Haicheng Yuan, Ying Mu, Yi He, Fang Xie, Xiao-Shuang Feng, Jia-Xin Xie, Xin-Ru Pan, Yu-Fei Wang, Jian Gong, Xiaoming Zheng, Peng-Fei Wang

“…Gene Ontology (GO) analysis showed that one term directly related to the “immune response” was shared between upregulated genes in Rep-MG and Rep-Mo/MΦ, while the other terms related to immune functions and other biofunctions were different between Rep-MG and Rep-Mo/MΦ, indicative of significantly different immune responses to brain injury between MG and MΦ. …”
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The role of mangroves in early-life trophic interactions supporting fishery production in the Galapagos by José Pontón-Cevallos, José Pontón-Cevallos, Anna-Maria Vafeiadou, Nicolas Moity, Jorge Ramírez-González, María José Rendón, Mercy J. Borbor-Cordova, Tom Moens, Jorge R. Bermudez-Monsalve, Peter Goethals

“…These results highlight the dominant role of local hydrophysical conditions and water quality in shaping mangrove nursery functions, surpassing the influence of broader regional factors. …”
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Climate, soil and management factors drive the quantitative relationships between soil fertility and spring maize water productivity in northern China by Jiao Shi, Minggang Xu, Xinhua He, Huaiping Zhou, Jianhua Li

“…The potential QRs determined by boundary functions were reached up to 6.2, 5.26 and 6.12 kg m−3 in NW, at dry years and under NPK, respectively. …”
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Fc-competent TIGITx4-1BB bispecific antibody exerts potent long-lasting antitumor activity by potentiating CD8+ T cell activity and Fcγ receptor-mediated modulation of the tumor mi... by Sang Hoon Lee, Jonghwa Won, Sora Kim, Wonjun Son, Yangsoon Lee, Yelim Park, Kyeong-Su Park, Hyunseong Youn, Arim Seo, Byungje Sung

“…This study investigated whether ABL112, an Fc-competent bispecific antibody targeting TIGIT and 4-1BB (TIGITx4-1BB), would enhance antitumor activity via Fcγ receptor (FcγR)-mediated macrophage activation and antibody-dependent cell-mediated functions.Methods TIGIT-dependent 4-1BB activation and TIGIT-blocking activity were assessed using reporter Jurkat T cell lines expressing 4-1BB and TIGIT, respectively. …”
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Plasma microRNA signatures of aging and their links to health outcomes and mortality: findings from a population-based cohort study by Lieke M. Kuiper, Michelle M. J. Mens, Julia W. Wu, Jaap Goudsmit, Yuan Ma, Liming Liang, Albert Hofman, Trudy Voortman, M. Arfan Ikram, Jeroen G. J. van Rooij, Joyce B. J. van Meurs, Mohsen Ghanbari

“…Elevated scores on these microRNA-based aging biomarkers were associated with unfavorable health outcomes, including lower subjective physical functioning and self-reported health and increased mortality and frailty risk, but not with first- or multi-morbidity. …”
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Legal Challenges of Marine Insurance Laws in the Use of Unmanned Ships by Mahsa Bahadoran- Baghbaderani, Masoud Shirani, Reza Soltani

“…Additionally, the research underscores the need for insurers to reevaluate the functionality of conventional hull insurance and explore the design of new insurance models that account for emerging risks and the interplay between hull insurance and other coverage types. …”
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Shifting sands to sustainable soils: Spatial dynamics of soil water and salinity in a desert oasis ecotone by Qiqi Cao, Tao Liu, Jiangbao Xia, Junran Li, Sujith Ravi, Zhiming Xin, Huijie Xiao

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Short communication: Nanoscale heterogeneity of U and Pb in baddeleyite from atom probe tomography – ²³⁸U series alpha recoil effects and U atom clustering by S. Denyszyn, D. W. Davis, D. Fougerouse

“…To constrain alpha recoil distance, a forward-modelling approach is presented where <span class="inline-formula">²⁰⁶</span>Pb redistribution functions were determined for a range of possible recoil distances. …”
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Characterization of bronchus-associated lymphoid tissue induced by co-exposure to Asian sand dust and ovalbumin: a study using 3D serial section imaging by Yoshikazu Mikami, Manabu Hayatsu, Etsushi Kuroda, Hiromasa Tsuda, Taku Toriumi, Yusuke Mizutani, Takamichi Ichinose, Akiko Honda, Hirohisa Takano, Hirohisa Takano, Hirohisa Takano

“…IntroductionInducible bronchus-associated lymphoid tissue (iBALT) develops with different morphologies and functions depending on the type of antigen, in which various cytokines, such as interleukin (IL)-1 and IL-17, and the cells producing them, such as T helper 17 (Th17) and T follicular helper (Tfh) cells, play an important role. …”
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Preliminary study of the mechanism of isolinderalactone inhibiting the malignant behavior of bladder cancer by Qun Wang, Wenkai Xu, Lu Ying, Hongjin Shi, Yuxin Sun, Wei Feng, Haole Xu, Jun Xie, Hairong Wei, Zhao Yang, Haifeng Wang

“…Isolinderalactone (ILL), extracted from the dried tubers of Linderae aggregate, has multiple functions, such as antioxidation, antitumor, and anti-infection effects. …”
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miR‐32533 Reduces Cognitive Impairment and Amyloid‐β Overload by Targeting CREB5‐Mediated Signaling Pathways in Alzheimer's Disease by Li Zeng, Zhongdi Cai, Jianghong Liu, Kaiyue Zhao, Furu Liang, Ting Sun, Zhuorong Li, Rui Liu

“…Bioinformatics and confirmatory experiments revealed that miR‐32533 had a novel 23‐base sequence with minimal coding potential, functioning within the Drosha ribonuclease III (Drosha)/Dicer 1, ribonuclease III (Dicer)‐dependent canonical pathway and identifiable via northern blot. miR‐32533 was abundantly brain‐distributed and downregulated in diverse AD‐related models, including APP/PS1 and five familial AD (5×FAD) mouse brains and AD patient plasma. …”
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RPL35A Downregulation Suppresses Hepatocellular Carcinoma Cell Proliferation via NCAPG2 Inactivation by Liang Chen, Yujie Lin, Yu Lai, Yanshan Li, Tao Chen, Xingxi Luo, Yibiao Ye

“…Beyond its canonical role, increasing evidence suggests that ribosomal proteins such as RPL35A may also exert extraribosomal functions that contribute to tumorigenesis. Methods We investigated RPL35A expression in HCC using tissue samples and cell lines. …”
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How topographic factors regulate vegetation vigor in reservoir drawdown zones with different levels of hydrological disturbances? by Xu Zhou, Zhaofei Wen, Shengjun Wu

“…Topography plays a fundamental role in shaping vegetation distribution, community structure, and ecosystem functioning. This influence remains significant in hydrologically complex environments, particularly in reservoir drawdown zones (RDZs). …”
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